Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 13601 - 13650 OF 15397 RESULTS

January 1, 1994

The contribution of open extremity fractures to infection in multiply injured patients

Injury, ISSN: 00201383

Naziri; William G. Cheadle; David H. Livingston; Jorge L. Rodriguez; Karen M. Starko; Hiram C. Polk

January 1, 1994

Assessment of aerosol delivery systems for recombinant human deoxyribonuclease

S.T.P. Pharma Sciences, ISSN: 11571489

Cipolla; Clark; Chan; Gonda; Steven J. Shire

January 1, 1994

Development of effective therapy for Alzheimer's disease based on neurotrophic factors

Neurobiology of Aging, ISSN: 01974580

Franz Hefti

January 1, 1994

Identification and characterization of batk, a predominantly brain‐specific non‐receptor protein tyrosine kinase related to Csk

Journal of Neuroscience Research, ISSN: 10974547 03604012

Sophia S. Kuo; Paul Moran; Gripp; Armanini; Phillips; Goddard; Caras

January 1, 1994

Inhibition of TNF by a TNF receptor immunoadhesin: Comparison to an anti- TNF monoclonal antibody

Journal of Immunology, ISSN: 00221767

Haak-Frendscho; Scot A. Marsters; Joyce Mordenti; Brady; Nancy Gillett; Chen; Avi Ashkenazi

January 1, 1994

Protection against rat endotoxic shock by p55 tumor necrosis factor (tnf) receptor immunoadhesin: Comparison with anti-tnf monoclonal antibody

Journal of Infectious Diseases, ISSN: 15376613 00221899

Hongkui Jin; Renhui Yang; Scot A. Marsters; Bunting; Florian M. Wurm; Steven M. Chamow; Avi Ashkenazi

January 1, 1994

Neurotrophic‐4/5 is a survival factor for embryonic midbrain dopaminergic neurons in enriched cultures

Journal of Neuroscience Research, ISSN: 10974547 03604012

Mary Hynes; Kris Poulsen; Armanini; Lucy R. Berkemeier; Phillips; Rosenthal

January 1, 1994

TGFβ2 and TGFβ3 are potent survival factors for midbrain dopaminergic neurons

Neuron, ISSN: 08966273

Kris Poulsen; Armanini; Robert D. Klein; Mary Hynes; Phillips; Rosenthal

January 1, 1994

Validation of a Variable Direction Hysteresis Minimization Pharmacodynamic Approach: Cardiovascular Effects of Alfentanil

Pharmaceutical Research, ISSN: 1573904X 07248741

Modi; Veng-Pedersen

January 1, 1994

Do antiidiotypic antibodies mimic antigen?

Research in Immunology, ISSN: 09232494

Amzel; Garcia; Desiderio

January 1, 1994

Major Degradation Products of Basic Fibroblast Growth Factor: Detection of Succinimide and Iso-aspartate in Place of Aspartate15

Pharmaceutical Research, ISSN: 1573904X 07248741

Shahrokh; Eberlein; Doug Buckley; Paranandi; Aswad; Stratton; Ron Mischak; Y. John Wang

January 1, 1994

ELISA for the neuropeptide degrading endopeptidase 3.4.24.11 in human serum and leukocytes

Peptides, ISSN: 01969781

Minzhong Zhang; Jochen Niehus; Thomas Schnellbacher; Silke Müller; Kristof Graf; Klaus D. Schultz; Claus R. Baumgarten; Catherine Lucas; Gert Kunkel

January 1, 1994

Pharmacokinetics and pharmacodynamics of recombinant proteins and peptides

Journal of Controlled Release, ISSN: 01683659

Modi

January 1, 1994

Feasibility Study on Spray-Drying Protein Pharmaceuticals: Recombinant Human Growth Hormone and Tissue-Type Plasminogen Activator

Pharmaceutical Research, ISSN: 1573904X 07248741

Mumenthaler; Chung C. Hsu; Rodney Pearlman

January 1, 1994

Cytokine regulation of lactate dehydrogenase-elevating virus: inhibition of viral replication by interferon-γ

Antiviral Research, ISSN: 01663542

William A. Cafruny; Sarahann E. Bradley; James J. Broen; Grace H.W. Wong

January 1, 1994

The Met Repressor‐Operator Complex: DNA Recognition by β‐Strands

Annals of the New York Academy of Sciences, ISSN: 17496632 00778923

Somers; Rafferty; PHILLIPS; Strathdee; He; McNALLY; Manfield; Navratil; Old; Saint-Girons; Stockley; Phillips

January 1, 1994

Immunological effects of insulin-like growth factor-I - Enhancement of immunoglobulin synthesis

Clinical and Experimental Immunology, ISSN: 00099104

Robbins; McCabe; Scheiner; Strasser; Ross Clark; Paula Jardieu

January 1, 1994

Effect of Recombinant Human Insulin-like Growth Factor I and Early Total Parenteral Nutrition on Immune Depression Following Severe Head Injury

Archives of Surgery, ISSN: 15383644 00040010

Kenneth A. Kudsk; Christine Mowatt Larssen; Julie Bukar; Timothy Fabian; Sherryl Oellerich; Daniel L. Dent; Rex Brown

January 1, 1994

Agrin-like proteins of the neuromuscular junction

Neurochemistry International, ISSN: 01970186

László Patthy; Nikolics

January 1, 1994

Pharmaco-toxicological expert report. Pulmozyme(®) rhDNase, Genentech, Inc.

Human and Experimental Toxicology, ISSN: 01445952

Green

January 1, 1994

rse, A novel receptor-type tyrosine kinase with homology to Ax1/Ufo, is expressed at high levels in the brain

Journal of Biological Chemistry, ISSN: 00219258

Melanie R Mark; David T. Scadden; Wang; Qimin Gu; Goddard; Godowski

January 1, 1994

Analytical considerations in the development of protein purification processes.

Bioprocess technology, ISSN: 08887470

Vincent R. Anicetti; William S. Hancock

January 1, 1994

Growth hormone-binding protein levels: Studies of children with short stature

Metabolism: Clinical and Experimental, ISSN: 00260495

Nelly Mauras; Carlsson; Suzanne Murphy; Thomas J. Merimee

January 1, 1994

Development of a single-shot subunit vaccine for HIV-1

AIDS Research and Human Retroviruses, ISSN: 08892229

Cleland; Powell; Lim; Barron; Berman; Eastman; Nunberg; Wrin; Vennari

January 1, 1994

The precision of anthropometric assessment of body fat distribution in children

Annals of Human Biology, ISSN: 03014460

Mueller; Kaplowitz

January 1, 1994

The interferon-γ receptor extracellular domain. Non-identical requirements for ligand binding and signaling

Journal of Biological Chemistry, ISSN: 00219258

Axelrod; Gibbs; David V. Goeddel

January 1, 1994

Artificial bone graft formulation for rhTGF-β1

Proceedings of the Controlled Release Society, ISSN: 10760458

Tue H. Nguyen; Cromwell; Wong; L. Steven Beck; Plouhar; Ongpipattanakul

January 1, 1994

Ron is a heterodimeric tyrosine kinase receptor activated by the HGF homologue MSP

EMBO Journal, ISSN: 02614189

Giovanni Gaudino; Antonia Follenzi; Luigi Naldini; Chiara Collesi; Massimo Santoro; Kathleen A. Gallo; Godowski; Paolo M. Comoglio

January 1, 1994

Regulation of experimental autoimmune neuritis by transforming growth factor-β1

Cellular Immunology, ISSN: 00088749

Shahik K. Gregorian; Wyne P. Lee; L. Steven Beck; Abdolmohamad Rostami; Edward P. Amento

January 1, 1994

An interleukin-4-induced transcription factor: IL-4 Stat

Science, ISSN: 00368075

Jinzhao Hou; Ulrike Schindler; William J. Henzel; Tze Chun Ho; Mike Brasseur; Steven L. McKnight

January 1, 1994

Neutrophil and B cell expansion in mice that lack the murine IL-8 receptor homolog

Science, ISSN: 00368075

Cacalano; James Lee; Kristine Kikly; Anne Ryan; Sharon Pitts-Meek; Hultgren; William I. Wood; Mark Moore

January 1, 1994

Effect of Interferon Gamma on Infection-Related Death in Patients With Severe Injuries: A Randomized, Double-blind, Placebo-Controlled Trial

Archives of Surgery, ISSN: 15383644 00040010

David J. Dries; Gregory J. Jurkovich; Ronald V. Maier; Terry P. Clemmer; Steven N. Struve; John A. Weigelt; Gregory G. Stanford; Daniel L. Herr; Howard R. Champion; Frank R. Lewis; David Hoyt; John Hansbrough; Albert E. Yellin; Thomas V. Berne; Donald D. Trunkey; Howard S. Jaffe; Catherine Munera; Peggy Fisher; Karen M. Starko

January 1, 1994

Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand

Nature, ISSN: 00280836

Frederic J. De Sauvage; Hass; Spencer; Malloy; Austin L. Gurney; Steven A. Spencer; Darbonne; William J. Henzel; Suzy C. Wong; Wun-Jing Kuang; Karl J. Oles; Hultgren; Lawrence A. Solberg Jr.; David V. Goeddel; Dan L. Eaton

January 1, 1994

Structure of the RGD protein decorsin: Conserved motif and distinct function in leech proteins that affect blood clotting

Science, ISSN: 00368075

Andrzej M. Krezel; Gerhard Wagner; Jana Seymour-Ulmer; Lazarus

January 1, 1994

Thrombocytopenia in c-mpl-deficient mice

Science, ISSN: 00368075

Austin L. Gurney; Karen Carver-Moore; Frederic J. De Sauvage; Mark Moore

January 1, 1994

Decreased sensitivity to tumour-necrosis factor but normal T-cell development in TNF receptor-2-deficient mice

Nature, ISSN: 00280836

Sharon Erickson; Frederic J. De Sauvage; Kristine Kikly; Karen Carver-Moore; Sharon Pitts-Meek; Nancy Gillett; Kathleen C. Sheehan; Schreiber; David V. Goeddel; Mark Moore

January 1, 1994

Delayed-type hypersensitivity response in experimental autoimmune neuritis treated with peptide-coupled spleen cells

Journal of Neuroimmunology, ISSN: 01655728

Shahik K. Gregorian; Abdolmohamad Rostami

January 1, 1994

Assay Systems for the Growth Hormone-Binding Protein

Proceedings of the Society for Experimental Biology and Medicine, ISSN: 15353699 00379727

Carlsson; Moises Mercado; Gerhard Baumann; Mark Stene; Kenneth M. Attie; Marcel Reichert; Kerstin Albertsson-Wikland; Kelly Dawson; Wai Lee T. Wong

January 1, 1994

IV. Yeast sequencing reports. Nucleotide sequence of the SAC2 gene of Saccharomyces cerevisiae

Yeast, ISSN: 10970061 0749503X

Ralf Kölling; Angela Lee; Ellson Y. Chen; David Botstein

January 1, 1994

A liquid‐phase binding analysis for L‐selectin: A strong dependency on highly clustered sulfate groups

European Journal of Biochemistry, ISSN: 14321033 00142956

Tomoaki YOSHIDA; Christopher Fennie; Lasky; Yuan C. LEE

January 1, 1994

The stoichiometry of growth hormone-binding protein complexes in human plasma: Comparison with cell surface receptors

Journal of Clinical Endocrinology and Metabolism, ISSN: 19457197 0021972X

Gerhard Baumann; Henry B. Lowman; Moises Mercado; James A. Wells

January 1, 1994

Receptor dimerization determines the effects of growth hormone in primary rat adipocytes and cultured human IM-9 lymphocytes

Endocrinology, ISSN: 00137227

Mapoko M. Ilondo; Anders B. Damholt; Cunningham; James A. Wells; Pierre De Meyts; Ronald M. Shymko

January 1, 1994

Structural Characterization of a Novel Tetrasaccharide Attached to Ser-61 of Human Factor IX by Mass Spectrometry and 1H NMR Spectroscopy

Techniques in Protein Chemistry, ISSN: 10808914

Reed J. Harris; Basa; Victor Ling; Spellman; Kenneth J. Smith; John Glushka; Russell W. Carlson; Van Halbeek

January 1, 1994

Identification of 2-D Gel Proteins at the Femtomole Level by Molecular Mass Searching of Peptide Fragments in a Protein Sequence Database

Techniques in Protein Chemistry, ISSN: 10808914

William J. Henzel; Todd M. Billeci; Stults; Susan C. Wong; Christopher Grimley; Colin K. Watanabe

January 1, 1994

Variable Success of Peptide-Resin Cleavage and Deprotection Following Solid-Phase Synthesis

Techniques in Protein Chemistry, ISSN: 10808914

Gregg B. Fields; Ruth H. Angeletti; Steve A. Carr; Alan J. Smith; Stults; Lynn C. Williams; Janis D. Young

January 1, 1994

Functional role of type I and type II interferons in antiviral defense

Science, ISSN: 00368075

Ulrike Müller; Ulrich Steinhoff; Luiz F. L. Reis; Silvio Hemmi; Jovan Pavlovic; Rolf M. Zinkernagel; Michel Aguet

January 1, 1994

Addition of a bacterial alginate lyase to purulent cf sputum in vitro can result in the disruption of alginate and modification of sputum viscoelasticity

Pulmonary Pharmacology, ISSN: 09520600

Mrsny; Lazazzera; Daugherty; Schiller; Thomas W. Patapoff

December 15, 1993

Expression of GlyCAM-1, an endothelial ligand for L-selectin, is affected by afferent lymphatic flow

Journal of Immunology, ISSN: 00221767

Mebius; Dowbenko; Angelica Williams; Christopher Fennie; Lasky; Susan R. Watson

December 5, 1993

Affinity maturation of human growth hormone by monovalent phage display

Journal of Molecular Biology, ISSN: 00222836

Henry B. Lowman; James A. Wells

December 5, 1993

Comparison of a structural and a functional epitope

Journal of Molecular Biology, ISSN: 00222836

Cunningham; James A. Wells

Join Our Team

The little things we do every day add up to big breakthroughs. Making a difference in the lives of millions starts when you make a change in yours.

Two Scientists Walk Into a Bar

Two Scientists Walk Into a Bar

Listen to our podcast, where researchers talk about their work answering the toughest questions in human biology.