Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 13751 - 13800 OF 15397 RESULTS

January 1, 1993

Differential effects of transforming growth factor‐β1 and bone morphogenetic protein 4 on gene expression and differentiated function of preosteoblasts

Journal of Cellular Physiology, ISSN: 10974652 00219541

Hong Zhou; R. Glenn Hammonds; David M. Findlay; Martin; Ng

January 1, 1993

Multiple defects of immune cell function in mice with disrupted interferon-γ genes

Science, ISSN: 00368075

Dyana K. Dalton; Sharon Pitts-Meek; Satish Keshav; Figari; Allan Bradley; Stewart

January 1, 1993

Mechanism-based design of prolactin receptor antagonists

Journal of Biological Chemistry, ISSN: 00219258

Fuh; Colosi; William I. Wood; James A. Wells

January 1, 1993

Expression of the cytokine RANTES in human rheumatoid synovial fibroblasts. Differential regulation of RANTES and interleukin-8 genes by inflammatory cytokines

Journal of Biological Chemistry, ISSN: 00219258

Palaniswami Rathanaswami; Mohamed Hachicha; Michael D Sadick; Thomas J. Schall; Shaun R. McColl

January 1, 1993

Regulation of neutrophil interleukin 8 gene expression and protein secretion by LPS, TNF‐α, and IL‐1β

Journal of Cellular Physiology, ISSN: 10974652 00219541

Seitaro Fujishima; Andrew R. Hoffman; Thanh Vu; K.Jin Kim; Hui Zheng; David Daniel; Youngmee Kim; Ellen F. Wallace; James W. Larrick; Thomas A. Raffin

January 1, 1993

Factors predicting the response to growth hormone (GH) therapy in prepubertal children with GH deficiency

Journal of Clinical Endocrinology and Metabolism, ISSN: 19457197 0021972X

Sandra L. Blethen; Peter G. Compton; Barbara M. Lippe; Rosenfeld; Gilbert P. August; Ann J. Johanson

January 1, 1993

P- and E-selectin use common sites for carbohydrate ligand recognition and cell adhesion

Journal of Cell Biology, ISSN: 00219525

David V. Erbe; Susan R. Watson; Presta; Barry A. Wolitzky; Carroll Foxall; Brian K. Brandley; Lasky

January 1, 1993

Sulphation requirement for GlyCAM-1, an endothelial ligand for L-selectin

Nature, ISSN: 00280836

Yasuyuki Imai; Lasky; Steven D. Rosen

January 1, 1993

Neurotrophin gene expression by cell lines derived from human gliomas

Journal of Neuroscience Research, ISSN: 10974547 03604012

Wolfgang Hamel; Manfred Westphal; Szonyi; Escandon; Nikolics

January 1, 1993

Pharmacokinetic profile of recombinant human (Rh) inhibin a and activin a in the immature rat. i. serum profile of rh-inhibin a and rh-activin a in the immature female rat

Endocrinology, ISSN: 19457170 00137227

Woodruff; Lynne Krummen; Chen; Geralyn G. Deguzman; Lyon; Deborah L. Baly; David E. Allison; Shaily Garg; Wai Lee T. Wong; Nora Hebert; Mather; Cossum

January 1, 1993

Pharmacokinetic profile of recombinant human (Rh) inhibin a and activin a in the immature rat. ii. tissue distribution of [125i]rh-inhibin a and [125i]rh-activin a in immature female and male rats

Endocrinology, ISSN: 19457170 00137227

Woodruff; Lynne Krummen; Chen; Lyon; Hansen; Geralyn G. Deguzman; Covello; Mather; Cossum

January 1, 1993

Analysis of repeated measurement data using the nonlinear mixed effects model

Chemometrics and Intelligent Laboratory Systems, ISSN: 01697439

Davidian; Giltinan

January 1, 1993

Effects of G4120, a Arg-Gly-Asp containing synthetic platelet glycoprotein IIB/IIIA receptor antagonist, on arterial and venous thrombolysis with recombinant tissue-type plasminogen activator in dogs

Fibrinolysis and Proteolysis, ISSN: 02689499

Rapold; Herman K. Gold; Wu; Napier; Bunting; Desire Collen

January 1, 1993

Evidence for a rebound coagulation phenomenon after cessation of a 4-hour infusion of a specific thrombin inhibitor in patients with unstable angina pectoris

Journal of the American College of Cardiology, ISSN: 07351097

Herman K. Gold; Frank W. Torres; Harry D. Garabedian; Wendy Werner; Ik-Kyung Jang; Agha Khan; J.Nathan Hagstrom; Tsunehiro Yasuda; Robert C. Leinbach; John B. Newell; Edwin G. Bovill; David Stump; Desire Collen

January 1, 1993

The purely chronotropic effects of relaxin in the rat isolated heart

Journal of Pharmacy and Pharmacology, ISSN: 20427158 00223573

G. Roger Thomas; Richard L. Vandlen

January 1, 1993

Use of Single Photon Emission Computed Tomography in Aerosol Studies

Journal of Aerosol Medicine: Deposition, Clearance, and Effects in the Lung, ISSN: 15579026 08942684

Chan

January 1, 1993

Evidence supporting a role for cathepsin B in the generation of T cell antigenic epitopes of human growth hormone

Molecular Immunology, ISSN: 01615890

Gillian Bushell; Nelson; Chiu; Christopher Grimley; William J. Henzel; Burnier; Sherman Fong

January 1, 1993

Peritoneal fluid concentrations of the cytokine RANTES correlate with the severity of endometriosis

American Journal of Obstetrics and Gynecology, ISSN: 00029378

Omid Khorram; Robert N. Taylor; Isabelle P. Ryan; Thomas J. Schall; Daniel V. Landers

January 1, 1993

Comparative Pathology of Recombinant Murine Interferon-γ in Mice and Recombinant Human Interferon-γ in Cynomolgus Monkeys

International Review of Experimental Pathology, ISSN: 00747718

Timothy G. Terrell; Green

January 1, 1993

Analysis of polypeptides and proteins

Advanced Drug Delivery Reviews, ISSN: 0169409X

Andrew J.S. Jones

January 1, 1993

Regulation of insulin-like growth factor binding protein production by human luteinizing granulosa cells cultured in defined medium

Journal of Clinical Endocrinology and Metabolism, ISSN: 19457197 0021972X

Nicholas A. Cataldo; Woodruff; Linda C. Giudice

January 1, 1993

Identification and characterization of binding proteins for inhibin and activin in human serum and follicular fluids

Endocrinology, ISSN: 19457170 00137227

Lynne Krummen; Woodruff; Geralyn G. Deguzman; Edward T. Cox; Deborah L. Baly; Elizabeth Mann; Shaily Garg; Wai Lee T. Wong; Cossum; Mather

January 1, 1993

Hormonal induction of low affinity receptor guanylyl cyclase

EMBO Journal, ISSN: 02614189

Jewett; Koller; David V. Goeddel; David G Lowe

January 1, 1993

Generation and characterization of a competitive antagonist of human hepatocyte growth factor, HGF/NK1

Journal of Biological Chemistry, ISSN: 00219258

Lokker; Godowski

January 1, 1993

The Pharmacokinetics and Absorption of Recombinant Human Relaxin in Nonpregnant Rabbits and Rhesus Monkeys After Intravenous and Intravaginal Administration

Pharmaceutical Research, ISSN: 1573904X 07248741

Chen; Baron R. Reed; Tue H. Nguyen; Gaylord; Fuller; Joyce Mordenti

January 1, 1993

The Pharmacokinetics of Recombinant Human Relaxin in Nonpregnant Women After Intravenous, Intravaginal, and Intracervical Administration

Pharmaceutical Research, ISSN: 1573904X 07248741

Chen; Andrew J. Perlman; Spanski; Peterson; Sanders; Robert B. Jaffe; Martin; Yalcinkaya; Cefalo; Chescheir; Menard; Joyce Mordenti

January 1, 1993

Some general estimation methods for nonlinear mixed-effects models

Journal of Biopharmaceutical Statistics, ISSN: 15205711 10543406

Davidian; Giltinan

January 1, 1993

Recombinant porcine prorelaxin produced in Chinese hamster ovary cells is biologically active

Life Sciences, ISSN: 00243205

Ann L. Vu; Carla B. Green; Katherine F. Roby; Michael J. Soares; David T.W. Fei; Chen; Simon C.M. Kwok

January 1, 1993

Identification of a promiscuous inflammatory peptide receptor on the surface of red blood cells

Journal of Biological Chemistry, ISSN: 00219258

Kuldeep Neote; Darbonne; John R. Ogez; Richard Horuk; Thomas J. Schall

January 1, 1993

Ligand passing: The 75-kDa tumor necrosis factor (TNF) receptor recruits TNF for signaling by the 55-kDa TNF receptor

Journal of Biological Chemistry, ISSN: 00219258

Louis A. Tartaglia; Diane Pennica; David V. Goeddel

January 1, 1993

Recombinant human insulin-like growth factor binding protein-3 (rhIGFBP-3): Effects on the glycemic and growth promoting activities of rhIGF-1 in the rat

Growth Regulation, ISSN: 0956523X

Ross Clark; Deborah L. Mortensen; Reifsynder; Mohler; Etcheverry; Mukku

January 1, 1993

In Vitro Evaluation of Dexamethasone-β-D-Glucuronide for Colon-Specific Drug Delivery

Pharmaceutical Research, ISSN: 1573904X 07248741

Barbara Haeberlin; Rubas; Harold W. Nolen III; David R. Friend

January 1, 1993

Assignment of heregulin (HGL) to human chromosome 8p22-p11 by PCR analysis of somatic cell hybrid DNA

Genomics, ISSN: 08887543

James Lee; William I. Wood

January 1, 1993

Peptide Stability in Drug Development. II. Effect of Single Amino Acid Substitution and Glycosylation on Peptide Reactivity in Human Serum

Pharmaceutical Research, ISSN: 1573904X 07248741

Powell; Tracy Stewart; Laszlo Jr Otvos; Urge; Federico C. A. Gaeta; Alessandro Sette; Arrhenius; David Thoon; Ken Soda; Colon

January 1, 1993

Two FIA-based biosensor systems studied for bioprocess monitoring

Journal of Biotechnology, ISSN: 01681656

Scheper; Brandes; Hans E. Maschke; Plötz; Müller

January 1, 1993

RGD-containing peptides inhibit adhesion of 293 cells transfected with GpIIb/IIIa to fibrinogen: Comparison to inhibition of platelet aggregation

Blood Coagulation and Fibrinolysis, ISSN: 09575235

David T.W. Fei; John Lowe; Bodary; Bunting; McLean; Napier; Chen

January 1, 1993

Induction of somatostatin immunoreactivity in cultured ciliary ganglion neurons by activin in choroid cell-conditioned medium

Neuron, ISSN: 08966273

James N. Coulombe; Ralph H. Schwall; Annette S. Parent; Felix P. Eckenstein; Rae Nishi

January 1, 1993

A truncated erythropoietin receptor and cell death

Science, ISSN: 00368075

Schwall; Nakamura; Nakauchi

January 1, 1993

Growth response of children with non-growth-hormone deficiency and marked short stature during three years of growth hormone therapy

Journal of Pediatrics, ISSN: 00223476

Hopwood; Hintz; Gertner; Kenneth M. Attie; Ann J. Johanson; Joyce Baptista; Joyce Kuntze; Robert M. Blizzard; Cara; Chernausek; Selna L. Kaplan; Barbara M. Lippe; Plotnick; Saenger

January 1, 1993

Binding interactions of kistrin with platelet glycoprotein IIb‐IIIa: Analysis by site‐directed mutagenesis

Proteins: Structure, Function and Bioinformatics, ISSN: 10970134 08873585

Dennis; Paul J. Carter; Lazarus

January 1, 1993

Investigation of the processing of GLP-1(7-36)amide by membrane peptidases

Digestion, ISSN: 14219867 00122823

Gerard Patrick McGregor; Karin Hupe-Sodmann; Robert L. Bridenbaugh; Bodo Zimmermann; Hubert Thole; Burkhard Göke; Rüdiger Göke; Karlheinz Voigt

January 1, 1993

A slow clearing, Fibrin-Specific, PAI-1 resistant variant of t-PA (T103N, KHRR 296-299 AAAA)

Thrombosis and Haemostasis, ISSN: 03406245

Nicholas F. Paoni; Key; Refino; Alice M. Chow; Hung V. Nguyen; Lea Berleau; Julie M. Badillo; Luis Peña; Brady; Florian M. Wurm; John R. Ogez; William F. Bennett

January 1, 1993

An evaluation of mechanisms by which tolerance to organ-specific antigens is lost using a transgenic mouse model

Journal of Immunology, ISSN: 00221767

Martin; Mora-Worms; Catherine Lucas; Reynolds; Stewart

January 1, 1993

Functions of agrin and agrin-related proteins

Trends in Neurosciences, ISSN: 01662236

László Patthy; Nikolics

January 1, 1993

Structure-function studies of the t-PA molecule

Fibrinolysis and Proteolysis, ISSN: 02689499

William F. Bennett

January 1, 1993

Ultrasensitive plasmid mapping by high performance capillary electrophoresis

Electrophoresis, ISSN: 15222683 01730835

Hans E. Maschke; John Frenz; Belenkii; Karger; William S. Hancock

January 1, 1993

Separation of 21‐(R)‐ and 21‐(S)‐argatroban: Solubility and activity of the individual diastereoisomers

Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549

Thomas E. Rawson; Kimmie VanGorp; Yang; Timothy P. Kogan

January 1, 1993

Is rheumatoid arthritis driven by oligoclonal T cells?

Clinical and Experimental Rheumatology, ISSN: 0392856X

Edward P. Amento

January 1, 1993

Tissue-engineered, three-dimensional human dermis to study extracellular matrix formation in wound healing

Cutaneous and Ocular Toxicology, ISSN: 15569527

Francis C. Zeigler; Lee Landeen; Gail K. Naughton; Sandra R. Slivka

January 1, 1993

A 'roll' in acute inflammation

Current Biology, ISSN: 09609822

Lasky

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