Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 14001 - 14050 OF 15397 RESULTS

Loss of gene function through rapid mitotic cycles in the Drosophila embryo
Nature, ISSN: 00280836
Mike Rothe; Michael Pehl; Heike Taubert; Herbert Jäckle
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Activin-a inhibits progesterone production by macaque luteal cells in culture
Journal of Clinical Endocrinology and Metabolism, ISSN: 19457197 0021972X
John D. Brannian; Woodruff; Mather; Richard L. Stouffer
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Signal transduction by the platelet integrin αiibβ3: Induction of calcium oscillations required for protein-tyrosine phosphorylation and ligand-induced spreading of stably transfected cells
Molecular Biology of the Cell, ISSN: 10591524
Pelletier; Bodary; Levinson
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The effect of anorexia nervosa and refeeding on growth hormone-binding protein, the insulin-like growth factors (IGFs), and the IGF-binding proteins
Journal of Clinical Endocrinology and Metabolism, ISSN: 19457197 0021972X
Debra R. Counts; Harry Gwirtsman; Carlsson; Michael Lesem
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Characterization of two high affinity human interleukin-8 receptors
Journal of Biological Chemistry, ISSN: 00219258
James Lee; Richard Horuk; Glenn C. Rice; Bennett; Camerato; William I. Wood
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Structural consequences of mutation
Current Opinion in Biotechnology, ISSN: 09581669
Eigenbrot; Anthony A. Kossiakoff
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Variability of conformations at crystal contacts in BPTI represent true low‐energy structures: Correspondence among lattice packing and molecular dynamics structures
Proteins: Structure, Function and Bioinformatics, ISSN: 10970134 08873585
Anthony A. Kossiakoff; Michael Randal; Guenot; Charles Eignebrot
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Altered metabolic and adhesive properties and increased tumorigenesis associated with increased expression of transforming growth factor β1
Journal of Cell Biology, ISSN: 00219525
Arrick; Alfredo R. Lopez; Fred Elfman; Reinhard Ebner; Caroline H. Damsky; Rik Derynck
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K‐252b Selectively Potentiates Cellular Actions and trk Tyrosine Phosphorylation Mediated by Neurotrophin‐3
Journal of Neurochemistry, ISSN: 14714159 00223042
Beat Knüsel; David R. Kaplan; Winslow; Rosenthal; Louis E. Burton; Klaus D. Beck; Stuart Rabin; Nikolics; Franz Hefti
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Effects of recombinant insulin-like growth factor-I (IGF-I) and growth hormone on serum IGF-binding proteins in calorically restricted adults
Journal of Clinical Endocrinology and Metabolism, ISSN: 19457197 0021972X
Simon C. J. Young; Louis E. Underwood; Abbie Celniker; David R. Clemmons
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Editorial overview
Current Opinion in Structural Biology, ISSN: 0959440X
Raymond Salemme; James A. Wells
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Transcription and recombination of the murine RS element
Journal of Immunology, ISSN: 00221767
Loren E. Daitch; Mark Moore; Denise M. Persiani; Jeannine M. Durdik; Erik Selsing
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Conformational Effects in the Reversed-Phase Chromatographic Behavior of Recombinant Human Growth Hormone (rhGH) and N-Methionyl Recombinant Human Growth Hormone (Met-hGH)
Analytical Chemistry, ISSN: 15206882 00032700
Peter Oroszlan; Wicar; Shiaw-Lin Wu; Karger; Glen Teshima; Wu; William S. Hancock
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An isoform of protein disulfide isomerase isolated from chronic myelogenous leukemia cells alters complex formation between nuclear proteins and regulatory regions of interferon-inducible genes
Journal of Biological Chemistry, ISSN: 00219258
Johnson; William J. Henzel; Albert Deisseroth
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Polyethylene glycol enhanced refolding of bovine carbonic anhydrase B. Reaction stoichiometry and refolding model
Journal of Biological Chemistry, ISSN: 00219258
Cleland; Hedgepeth; Daniel I. C. Wang
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Effects of recombinant human insulin-like growth factor-I (rhIGF-I) on total and free IGF-I concentrations, IGF-binding proteins, and glycemic response in humans
Journal of Clinical Endocrinology and Metabolism, ISSN: 19457197 0021972X
Steven A. Lieberman; Julie Bukar; Chen; Abbie Celniker; Peter G. Compton; Cook; Albu; Andrew J. Perlman; Andrew R. Hoffman
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Neutralization of multiple laboratory and clinical isolates of human immunodeficiency virus type 1 (HIV-1) by antisera raised against gp120 from the MN isolate of HIV-1
Journal of Virology, ISSN: 0022538X
Berman; Matthews; Riddle; Mark Champe; Hobbs; Nakamura; Jennifer Mercer; Eastman; Catherine Lucas; Alphonse J. Langlois; Florian M. Wurm; Timothy Gregory
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α-Isoenzyme of alcohol dehydrogenase from monkey liver. Cloning, expression, mechanism, coenzyme, and substrate specificity
Journal of Biological Chemistry, ISSN: 00219258
Light; Dennis; Ian J. Forsythe; Liu; Green; Darla Ann Kratzer; Bryce V. Plapp
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Rational design of potent antagonists to the human growth hormone receptor
Science, ISSN: 00368075
Fuh; Cunningham; Rikiro Fukunaga; Shigekazu Nagata; David V. Goeddel; James A. Wells
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Molecular cloning and expression of the murine RANTES cytokine: structural and functional conservation between mouse and man
European Journal of Immunology, ISSN: 15214141 00142980
Thomas J. Schall; Simpson; John Mak
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Multiple elements within the glucocorticoid regulatory unit of the rat α1-acid glycoprotein gene are recognition sites for C/EBP
Journal of Biological Chemistry, ISSN: 00219258
Thomas Ratajczak; Williams; Diego DiLorenzo; Gordon M. Ringold
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Identification of heregulin, a specific activator of p185erbB2
Science, ISSN: 00368075
William E. Holmes; Mark X. Sliwkowski; Robert W. Akita; William J. Henzel; James Lee; Park; Yansura; Nasrin Abadi; Helga Raab; Gail D. Lewis; Shepard; Wun-Jing Kuang; William I. Wood; David V. Goeddel; Richard L. Vandlen
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Diagnostic utility of DNA content flow cytometry in follicular neoplasms of the thyroid
Journal of Surgical Oncology, ISSN: 10969098 00224790
Harlow; Duda; Kenneth D. Bauer
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Gonadotropin-releasing hormone, inhibin, and activin in human placenta: Evidence for a common cellular localization
Journal of Clinical Endocrinology and Metabolism, ISSN: 19457197 0021972X
Petraglia; Woodruff; Giovanna Botticelli; Annibale Botticelli; Andrea R. Genazzani; Kelly E. Mayo; Wylie Vale
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Homeodomain-independent activity of the fushi tarazu polypeptide in Drosophila embryos
Nature, ISSN: 00280836
V. Danial Fitzpatrick; Anthony Percival-Smith; C. James Ingles; Henry M. Krause
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Properties of spontaneous growth hormone secretory bursts and half-life of endogenous growth hormone in boys with idiopathic short stature. Genentech Collaborative Group
Journal of Clinical Endocrinology and Metabolism, ISSN: 19457197 0021972X
Johannes D. Veldhuis; Alan D. Rogol; Paul M. Martha Jr.; Ann J. Johanson; Robert M. Blizzard; Cara; James W. Frane; Gertner; Hintz; Chernausak; Nancy Hopwood; Selna Kaplan; Kirkland; Barbara M. Lippe; Leslie Plotnick; Saenger; Barry M. Sherman
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Expression of serum insulin-like growth factors, insulin-like growth factor-binding proteins, and the growth hormone-binding protein in heterozygote relatives of Ecuadorian growth hormone receptor deficient patients
Journal of Clinical Endocrinology and Metabolism, ISSN: 19457197 0021972X
Fielder; Jaime Guevara-Aguirret; Arlan L. Rosenbloom; Carlsson; Hintz; Rosenfeld
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Dominant negative mutants of transforming growth factor-β1 inhibit the secretion of different transforming growth factor-β isoforms
Molecular and Cellular Biology, ISSN: 02707306
Alfredo R. Lopez; Cook; Prescott L. Deininger; Rik Derynck
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Characterization of the human 5-hydroxytryptamine(1B) receptor
Journal of Biological Chemistry, ISSN: 00219258
Hui Jin; Donna Oksenberg; Avi Ashkenazi; Peroutka; Alessandra M. V. Duncan; Richard Rozmahel; Yilli Yang; Mengod; Jose M. Palacios; Brian F. O'Dowd
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Association of the M(r) 58,000 postsynaptic protein of electric tissue with Torpedo dystrophin and the M(r) 87,000 postsynaptic protein
Journal of Biological Chemistry, ISSN: 00219258
Margaret H. Butler; Karen Douville; Amy Murnane; Kramarcy; Jonathan B. Cohen; Robert Sealock; Stanley C. Froehner
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Identification of cysteine-rich domains of the type 1 tumor necrosis factor receptor involved in ligand binding
Journal of Biological Chemistry, ISSN: 00219258
Scot A. Marsters; Frutkin; Simpson; Brian M. Fendly; Avi Ashkenazi
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Effects of intravenous IL-8 administration in nonhuman primates
Journal of Immunology, ISSN: 00221767
Kimberly J. Van Zee; Eva Fischer; Arthur S. Hawes; Hébert; Timothy G. Terrell; Baker; Stephen F. Lowry; Lyle L. Moldawer
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Identification of proteins binding to interferon-inducible transcriptional enhancers in hematopoietic cells
Journal of Biological Chemistry, ISSN: 00219258
Andrzej Wedrychowski; William J. Henzel; Laurel Huston; Paslidis; Debra Ellerson; Michele McRae; David Seong; O. M. Zack Howard; Albert Deisseroth
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Natural bovine osteogenin and recombinant human bone morphogenetic protein-2B are equipotent in the maintenance of proteoglycans in bovine articular cartilage explant cultures
Journal of Biological Chemistry, ISSN: 00219258
Frank P. Luyten; Yu M. Yu; Masaki Yanagishita; Slobodan Vukicevic; R. Glenn Hammonds; Reddi
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Prevention of HIV-1 infection in chimpanzees by gpl20 V3 domain-specific monoclonal antibody
Nature, ISSN: 00280836
Emini; Schleif; Nunberg; Conley; Eda; Tokiyoshi; Putney; Matsushita; Cobb; Jett; Eichberg; Murthy
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Genetic linkage of Werner's syndrome to five markers on chromosome 8
Nature, ISSN: 00280836
Makoto Goto; Mark Rubenstein; James Weber; Kathryn Woods; Drayna
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High level Escherichia coli expression and production of a bivalent humanized antibody fragment
Bio/Technology, ISSN: 0733222X
Paul J. Carter; Robert F. Kelley; Maria L. Rodrigues; Snedecor; Michael Covarrubias; Mark Velligan; Wai T. Wong Lee; Rowland; Claire Kotts; Monique E. Carver; Yang; James H. Bourell; Michael Shepard; Henner
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Predictors of mortality among HIV-infected women in Kigali, Rwanda
Annals of Internal Medicine, ISSN: 00034819
Christina P. Lindan; Susan Allen; Antoine Serufilira; Alan R. Lifson; Philippe Van De Perre; Amy Chen Rundle; Jean Batungwanayo; Francois Nsengumuremyi; Joseph Bogaerts; Stephen Hulley
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Characterization of complementary DNA clones encoding the rabbit IL-8 receptor
Journal of Immunology, ISSN: 00221767
James Lee; Wun-Jing Kuang; Glenn C. Rice; William I. Wood
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Mechanism of polyethylene glycol interaction with the molten globule folding intermediate of bovine carbonic anhydrase B
Journal of Biological Chemistry, ISSN: 00219258
Cleland; Theodore W. Randolph
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Molecular and biological properties of the vascular endothelial growth factor family of proteins
Endocrine Reviews, ISSN: 0163769X 0163769X
Napoleone Ferrara; Houck; Lyn B. Jakeman; Leung
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Delivery of recombinant human growth hormone to rats during exposure to microgravity on NASA Space Shuttle Discovery.
Physiologist, ISSN: 00319376
Cronin; John E. Battersby; William S. Hancock; Ralph H. Schwall; Ross Clark
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Stage-specific binding of inhibin and activin to subpopulations of rat germ cells
Endocrinology, ISSN: 19457170 00137227
Woodruff; James Borree; Kenneth M. Attie; Edward T. Cox; Glenn C. Rice; Mather
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Uncoupling of cytokine mRNA expression and protein secretion during the induction phase of T cell anergy
Journal of Immunology, ISSN: 00221767
Thomas J. Schall; O'Hehir; David V. Goeddel; Jonathan R. Lamb
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Transforming growth factor-β1 inhibits postischemic increases in splanchnic vascular resistance
Biotechnology Therapeutics, ISSN: 08982848
G. Roger Thomas; Thibodaux
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Quality control issues in the analysis of lyophilized proteins.
Developments in biological standardization, ISSN: 03015149
Baffi; Robert L. Garnick
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Involvement of residues 296-299 in the enzymatic activity of tissue-type plasminogen activator
Protein Engineering, Design and Selection, ISSN: 17410134 17410126
Nicholas; Canio; Brady; Luis; Hung; Elizabeth; Adriana; Florian; Robert Reis; David Botstein; William
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The Disposition of a Human Relaxin (hRlx-2) in Pregnant and Nonpregnant Rats
Pharmaceutical Research, ISSN: 1573904X 07248741
Cossum; Dwyer; Michael Roth; Chen; Moffat; Richard L. Vandlen; Ferraiolo
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HepG2 cells predominantly express the type II interleukin 1 receptor (biochemical and molecular characterization of the IL-1 receptor)
Cytokine, ISSN: 10434666
Judith G. Giri; Richard Robb; Wai Lee T. Wong; Richard Horuk
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Evidence for a third transcript from the human factor VIII gene
Genomics, ISSN: 10898646 08887543
Barbara Levinson; Susan Kenwrick; Pamela Gamel; Karen L. Fisher; Jane Gitschier
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