Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 14051 - 14100 OF 15397 RESULTS

January 1, 1992

Relaxin alone and in conjunction with interferon-γ decreases collagen synthesis by cultured human scleroderma fibroblasts

Journal of Investigative Dermatology, ISSN: 15231747 0022202X

Elaine N. Unemori; Eugene A. Bauer; Edward P. Amento

January 1, 1992

Conjugation of soluble CD4 without loss of biological activity via a novel carbohydrate-directed cross-linking reagent

Journal of Biological Chemistry, ISSN: 00219258

Steven M. Chamow; Timothy P. Kogan; Peers; Hastings; Randal A. Byrn; Avi Ashkenazi

January 1, 1992

Systematic mutational analysis of cAMP-dependent protein kinase identifies unregulated catalytic subunits and defines regions important for the recognition of the regulatory subunit

Journal of Biological Chemistry, ISSN: 00219258

Gibbs; Knighton; Sowadski; Taylor; Zoller

January 1, 1992

Endocytosis of glycophospholipid-anchored and transmembrane forms of CD4 by different endocytic pathways

EMBO Journal, ISSN: 02614189

Gilbert-Andre Keller; Mark Siegel; Caras

January 1, 1992

Bioequivalence

Pharmaceutical Research, ISSN: 1573904X 07248741

Rescigno

January 1, 1992

Osteoblast-specific expression of growth hormone stimulates bone growth in transgenic mice

Molecular and Cellular Biology, ISSN: 02707306

Baker; Hollingshead; Sharon Pitts-Meek; Hansen; Taylor; Stewart

January 1, 1992

Randomized angiographic trial of recombinant tissue-type plasminogen activator (alteplase) in myocardial infarction

Journal of the American College of Cardiology, ISSN: 07351097

Robert J. Carney; Gregory A. Murphy; Thomas R. Brandt; Patrick J. Daley; Ernest Pickering; Harvey J. White; Timothy J. McDonough; Suzanne K. Vermilya; Sam L. Teichman; The Raami Study Investigators

January 1, 1992

Tumor necrosis factor receptor signaling. A dominant negative mutation suppresses the activation of the 55-kDa tumor necrosis factor receptor

Journal of Biological Chemistry, ISSN: 00219258

Louis A. Tartaglia; David V. Goeddel

January 1, 1992

Natural history of human immunodeficiency virus type 1 infection in children: Prognostic value of laboratory tests on the bimodal progression of the disease

Pediatric Infectious Disease Journal, ISSN: 08913668

A-M. Duliege; Messiah; Blanche; Tardieu; Griscelli; Spira

January 1, 1992

Estimation of Permanence Time, Exit Time, Dilution Factor, and Steady-State Volume of Distribution

Pharmaceutical Research, ISSN: 1573904X 07248741

Joyce Mordenti; Rescigno

January 1, 1992

Interleukin 8 in rheumatoid and osteoarthritis

Scandinavian Journal of Rheumatology, ISSN: 03009742

Symons; Wai Lee T. Wong; Michael A. Palladino; Duff

January 1, 1992

Six-year results of a randomized, prospective trial of human growth hormone and oxandrolone in Turner syndrome

Journal of Pediatrics, ISSN: 00223476

Rosenfeld; James France; Kenneth M. Attie; Jo Anne Brasel; Stephen Burstein; Cara; Chernausek; Ronald W. Gotlin; Joyce Kuntze; Barbara M. Lippe; Patrick C. Mahoney; Wayne V. Moore; Saenger; Ann J. Johanson

January 1, 1992

Cytokine stimulation of human basophil histamine release.

Immunology series, ISSN: 00926019

Haak-Frendscho; Allen P. Kaplan

January 1, 1992

CD4 immunoadhesins in anti-HIV therapy: New developments

International journal of cancer. Supplement = Journal international du cancer. Supplement, ISSN: 00207136

Steven M. Chamow; A-M. Duliege; Arthur J. Ammann; Kahn; Allen; Eichberg; Randal A. Byrn; Capon; Ward; Avi Ashkenazi

January 1, 1992

The colon as a site for drug delivery

Journal of Controlled Release, ISSN: 01683659

Mrsny

January 1, 1992

Transplacental passage of a human relaxin administered to rhesus monkeys

Obstetrical and Gynecological Survey, ISSN: 15339866 00297828

Cossum; Hill; Bailey; Anderson; Slikker

January 1, 1992

An evaluation of the functions of the 22-kilodalton (Kda), the 20-kda, and the n-terminal polypeptide forms of human growth hormone using transgenic mice

Endocrinology, ISSN: 19457170 00137227

Stewart; Shirley Clift; Sharon Pitts-Meek; Martin; Timothy G. Terrell; Denny Liggitt; Oakley

January 1, 1992

A randomized prospective clinical trial to determine the efficacy of interferon-γ in severely injured patients

American Journal of Surgery, ISSN: 00029610

Hiram C. Polk; William G. Cheadle; David H. Livingston; Jorge L. Rodriguez; Karen M. Starko; Allen Izu; Howard S. Jaffe; Gerald Sonnenfeld

January 1, 1992

D-factor and growth hormone enhance tumor necrosis factor-induced increase of Mn superoxide dismutase mRNA and oxygen tolerance

Cytokine, ISSN: 10434666

Min-Fu Tsan; Julie E. White; Grace H.W. Wong

January 1, 1992

Photolabelling of Salmonella typhimurium LT2 sialidase: Identification of a peptide with a predicted structural similarity to the active sites of influenza-virus sialidases

Biochemical Journal, ISSN: 02646021

Warner; Reed J. Harris; Robert S. McDowell; Vimr

January 1, 1992

Engineering a humanized bispecific F(ab')2 fragment for improved binding to T cells

International Journal of Cancer, ISSN: 00207136

Maria L. Rodrigues; Shalaby; Winifred Werther; Presta; Paul J. Carter

January 1, 1992

Characterization of the recombinant human receptor for Escherichia coli heat-stable enterotoxin

Journal of Biological Chemistry, ISSN: 00219258

Frederic J. De Sauvage; Richard Horuk; Bennett; Quan; Burnier; David V. Goeddel

January 1, 1992

Antiviral activity of tumor necrosis factor (TNF) is signaled through the 55-kDa receptor, type I TNF

Journal of Immunology, ISSN: 00221767

Grace H.W. Wong; Louis A. Tartaglia; Lee; David V. Goeddel

January 1, 1992

Radioiodination of the active site of tissue plasminogen activator: A method for radiolabeling serine proteases with tyrosylprolylarginyl chloromethyl ketone

Analytical Biochemistry, ISSN: 10960309 00032697

Keyt; Lea Berleau; Hung V. Nguyen; William F. Bennett

January 1, 1992

Human recombinant transforming growth factor-β1 modulation of biochemical and cellular events in healing of ulcer wounds

Journal of Investigative Dermatology, ISSN: 15231747 0022202X

Theresa L. Chen; Rebecca L. Bates; Yvette Xu; Arthur J. Ammann; Steven Beck

January 1, 1992

Permeability Characteristics of Various Intestinal Regions of Rabbit, Dog, and Monkey

Pharmaceutical Research, ISSN: 1573904X 07248741

Nancy Jezyk; Rubas; George M. Grass

January 1, 1992

Regulation of growth of normal ovarian epithelial cells and ovarian cancer cell lines by transforming growth factor-β

American Journal of Obstetrics and Gynecology, ISSN: 00029378

Andrew Berchuck; Gus Rodriguez; George Olt; Regina Whitaker; Matthew P. Boente; Arrick; Daniel L. Clarke-Pearson; Robert C. Bast Jr.

January 1, 1992

Rapid evolution of peptide and protein binding properties in vitro

Current Opinion in Structural Biology, ISSN: 0959440X

James A. Wells; Henry B. Lowman

January 1, 1992

Growth hormone and renal glutamine and glutamate handling

Journal of the American Society of Nephrology, ISSN: 10466673

Welbourne; Horton; Cronin

January 1, 1992

Selecting: Interpreters of cell-specific carbohydrate information during inflammation

Science, ISSN: 00368075

Lasky

January 1, 1992

Molecular cloning of a retina-specific membrane guanylyl cyclase

Neuron, ISSN: 08966273

Andrew W. Shyjan; Frederic J. De Sauvage; Nancy Gillett; David V. Goeddel; David G Lowe

January 1, 1992

Rapid evolution of peptide and protein binding properties in vitro

Current Opinion in Biotechnology, ISSN: 09581669

James A. Wells; Henry B. Lowman

January 1, 1992

A zymogenic tissue plasminogen activator variant: The Phe305→ His mutation suppresses fibrin(ogen) stimulated plasminogen activation by one chain t-PA

Fibrinolysis and Proteolysis, ISSN: 02689499

Deborah L. Higgins; Young; Powers; Anderson

January 1, 1992

Comparison of second messenger formation in human keratinocytes following stimulation with epidermal growth factor and bradykinin

Second Messengers and Phosphoproteins, ISSN: 08957479

Johnson; King; Vera B. Morhenn

January 1, 1992

Pharmaceutics of protein drugs

Journal of Pharmacy and Pharmacology, ISSN: 00223573

Rodney Pearlman; Tue H. Nguyen

January 1, 1992

Conservation of the kinaselike regulatory domain is essential for activation of the natriuretic peptide receptor guanylyl cyclases

Molecular and Cellular Biology, ISSN: 02707306

Koller; Frederic J. De Sauvage; David G Lowe; David V. Goeddel

January 1, 1992

Human growth hormone and extracellular domain of its receptor: Crystal structure of the complex

Science, ISSN: 00368075

De Vos; Ultsch; Anthony A. Kossiakoff

January 1, 1992

A simple method for the preparation of single-stranded polydeoxynucleotides of desired length

BioTechniques, ISSN: 07366205

White; Drossman; Drayna

January 1, 1992

Cloning, expression during development, and evidence for release of a trophic factor for ciliary ganglion neurons

Neuron, ISSN: 08966273

Leung; Annette S. Parent; Cachianes; Esch; James N. Coulombe; Nikolics; Felix P. Eckenstein; Rae Nishi

January 1, 1992

Synthesis and biological activity of a 5,6-substituted teleocidin

Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X

Robert R. Webb II; Michael C. Venuti

January 1, 1992

The synthesis of a phorbol 12,13-bis-lactone

Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X

Thomas E. Rawson; Timothy P. Kogan

January 1, 1992

Human recombinant soluble decay accelerating factor inhibits complement activation in vitro and in vivo

Journal of Immunology, ISSN: 00221767

Paul Moran; Beasley; Gorrell; Martin; Gribling; Henry J. Fuchs; Nancy Gillett; Louis E. Burton; Caras

January 1, 1992

Integration and stability of CHO amplicons containing plasmid sequences

Developments in biological standardization, ISSN: 03015149

Florian M. Wurm; Maria G. Pallavicini; Arathoon

January 1, 1992

Strontium-90 induced bone tumours in beagle dogs: Effects of route of exposure and dose rate

International Journal of Radiation Biology, ISSN: 09553002

Nancy Gillett; Pool; Taylor; Muggenburg; Boecker

January 1, 1992

Nucleotide sequence selection for increased expression of heterologous genes in Escherichia coli

Methods, ISSN: 10959130 10462023

Yansura; Laura C. Simmons

January 1, 1992

Structure-function analysis of hepatocyte growth factor: Identification of variants that lack mitogenic activity yet retain high affinity receptor binding

EMBO Journal, ISSN: 02614189

Lokker; Melanie R Mark; Luis; Bennett; Robbins; Baker; Godowski

January 1, 1992

Molecular structural basis of ligand selectivity for 5-HT2 versus 5-HT1C cortical receptors

Naunyn-Schmiedeberg's Archives of Pharmacology, ISSN: 14321912 00281298

Pierce; Joanne Y. Kim; Peroutka

January 1, 1992

Paracrine Regulation of Reproductive Function by Inhibin and Activin

Proceedings of the Society for Experimental Biology and Medicine, ISSN: 15353699 00379727

Mather; Woodruff; Lynne Krummen

January 1, 1992

The cytoplasmic domain of tissue factor is phosphorylated by a protein kinase C-dependent mechanism

Journal of Biological Chemistry, ISSN: 00219258

Zioncheck; Roy; Gordon A. Vehar

January 1, 1992

The gene encoding human plasma carboxypeptidase B (CPB2) resides on chromosome 13

Genomics, ISSN: 10898646 08887543

Siao Ping Tsai; Drayna

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