Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 14201 - 14250 OF 15397 RESULTS

January 1, 1991

Molecular genetics and drug discovery.

Molecular genetic medicine, ISSN: 10572805

Michael C. Venuti

January 1, 1991

Crystal structure of recombinant rabbit interferon-γ at 2.7-Å resolution

Journal of Biological Chemistry, ISSN: 00219258

Cleopas T. Samudzi; Louis E. Burton; Rubin

January 1, 1991

The vascular endothelial growth factor family: Identification of a fourth molecular species and characterization of alternative splicing of rna

Molecular Endocrinology, ISSN: 19449917 08888809

Houck; Napoleone Ferrara; Jane Winer; Cachianes; Bing Li; Leung

January 1, 1991

Organ specific cytokine therapy: Local activation of mononuclear phagocytes by delivery of an aerosol of recombinant interferon-γ to the human lung

Journal of Clinical Investigation, ISSN: 00219738

Ari Jaffe; Roland Buhl; Andrea Mastrangeli; Kenneth J. Holroyd; Saltini; Dorothy Czerski; Howard S. Jaffe; Susan M. Kramer; Stephen A. Sherwin; Crystal

January 1, 1991

Monovalent phage display: A method for selecting variant proteins from random libraries

Methods, ISSN: 10959130 10462023

Henry B. Lowman; James A. Wells

January 1, 1991

Structure-activity relationship study of human interleukin-3: Role of the C-terminal region for biological activity

EMBO Journal, ISSN: 02614189

Lokker; Gerhard Zenke; Ulrike Strittmatter; Barbara Fagg; N. Rao Movva

January 1, 1991

West Coast Parenteral Drug Association Genetic Stability Symposium 10-12 April 1991, San francisco, California

Biologicals, ISSN: 10958320 10451056

Robert L. Garnick

January 1, 1991

Platelet-derived growth factor activity and mrna expression in healing vascular grafts in baboons association in vivo of platelet-derived growth factor mRNA and protein with cellular proliferation

Journal of Clinical Investigation, ISSN: 00219738

Michael A. Golden; Tina Au; Thomas R. Kirkman; Josiah N. Wilcox; Elaine W. Raines; Russell Ross; Alexander W. Clowes

January 1, 1991

Interspecies Scaling of Clearance and Volume of Distribution Data for Five Therapeutic Proteins

Pharmaceutical Research, ISSN: 1573904X 07248741

Joyce Mordenti; Chen; Moore; Ferraiolo; Green

January 1, 1991

Functional expression of mammalian adenosine cyclic monophosphate-dependent protein kinase in saccharomyces cerevisiae

Methods in Enzymology, ISSN: 15577988 00766879

Zoller; Karen E. Johnson; Wes M. Yonemoto; Levin

January 1, 1991

Fusion of sequence elements from non-anchored proteins to generate a fully functional signal for glycophosphatidylinositol membrane anchor attachment

Journal of Cell Biology, ISSN: 00219525

Paul Moran; Caras

January 1, 1991

Cloning and sequencing of the cDNA encoding the rubber elongation factor of hevea brasiliensis

Plant Physiology, ISSN: 00320889

Elisabeth Goyvaerts; Dennis; Light; Nam-Hai Chua

January 1, 1991

Bone morphogenetic protein‐2b stimulation of growth and osteogenic phenotypes in rat osteoblast‐like cells: Comparison with TGF‐β1

Journal of Bone and Mineral Research, ISSN: 15234681 08840431

Theresa L. Chen; Rebecca L. Bates; Andrew Dudley; Glenn Hammonds Jr.; Edward P. Amento

January 1, 1991

Structure and function in recombinant HIV-1 gp120 and speculation about the disulfide bonding in the gp120 homologs of HIV-2 and SIV

Advances in Experimental Medicine and Biology, ISSN: 0065275X

Timothy Gregory; James A. Hoxie; Watanabe; Spellman

January 1, 1991

Long-term inhibition of tumor growth by tumor necrosis factor in the absence of cachexia or T-cell immunity

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Teng; Ben H. Park; Koeppen; Kevin J. Tracey; Brian M. Fendly; Hans Schreiber

January 1, 1991

The Extracellular Domain of the Human Interferon Gamma Receptor Interacts with a Species-Specific Signal Transducer

Molecular and Cellular Biology, ISSN: 02707306

Gibbs; Steven R. Williams; Patrick W. Gray; Schreiber; Diane Pennica; Glenn C. Rice; David V. Goeddel

January 1, 1991

Defective endogenous retrovirus-like sequences and particles of Chinese hamster ovary cells.

Developments in biological standardization, ISSN: 03015149

Anderson; Yolanda S. Lie; Mari-Anne L. Low; Steven R. Williams; Florian M. Wurm; Dinowitz

January 1, 1991

Resistance of primary isolates of human immunodeficiency virus type 1 to soluble CD4 is independent of CD4-rgp120 binding affinity

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Avi Ashkenazi; Smith; Scot A. Marsters; Riddle; Timothy Gregory; David D. Ho; Capon

January 1, 1991

FAB assembly and enrichment in a monovalent phage display system

Bio/Technology, ISSN: 0733222X

Lisa J. Garrard; Yang; Mark P. O'Connell; Robert F. Kelley; Henner

January 1, 1991

Red blood cells are a sink for interleukin 8, a leukocyte chemotaxin

Journal of Clinical Investigation, ISSN: 00219738

Darbonne; Glenn C. Rice; Margorie A. Mohler; Ted Apple; Hébert; Anthony J. Valente; Baker

January 1, 1991

Nerve growth factor and the neostriatum

Progress in Neuro-Psychopharmacology and Biological Psychiatry, ISSN: 02785846

C.Anthony Altar

January 1, 1991

Interleukin 1 protects from cytosine arabinoside-induced alopecia in the rat model

FASEB Journal, ISSN: 08926638

Joaquin J. Jimenez; Grace H.W. Wong; Adel A. Yunis

January 1, 1991

Cytokines and growth factors positively and negatively regulate interstitial collagen gene expression in human vascular smooth muscle cells

Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN: 10795642

Edward P. Amento; Niloofar Ehsani; Helen Palmer; Peter Libby

January 1, 1991

Rational design of receptor-specific variants of human growth hormone

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Cunningham; James A. Wells

January 1, 1991

Inhibition of translation of transforming growth factor-β3 mRNA by its 5' untranslated region

Molecular and Cellular Biology, ISSN: 02707306

Arrick; Angela Lee; Richard L. Grendell; Rik Derynck

January 1, 1991

Mutations in human interferon gamma affecting inclusion body formation identified by a general immunochemical screen

Nature Biotechnology, ISSN: 0733222X

Wetzel; Jeanne Perry; Connie A. Veilleux

January 1, 1991

Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbloncogene product

Nature, ISSN: 00280836

Matthew J. Hart; Alessandra Eva; Tony Evans; Stuart A. Aaronson; Richard A. Cerione

January 1, 1991

The two different receptors for tumor necrosis factor mediate distinct cellular responses

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Louis A. Tartaglia; Weber; Figari; Reynolds; Michael A. Palladino; David V. Goeddel

January 1, 1991

Dimerization of the extracellular domain of the human growth hormone receptor by a single hormone molecule

Science, ISSN: 00368075

Cunningham; Ultsch; De Vos; Michael G. Mulkerrin; Karl R. Clauser; James A. Wells

January 1, 1991

Selection, expression, and nucleotide sequencing of the glutamate dehydrogenase gene of Peptostreptococcus asaccharolyticus

Journal of Bacteriology, ISSN: 00219193

Snedecor; Chu; Ellson Y. Chen

January 1, 1991

Identification of the human platelet GTPase activating protein for the CDC42Hs protein

Journal of Biological Chemistry, ISSN: 00219258

Matthew J. Hart; Katsuhiro Shinjo; Alan Hall; Tony Evans; Richard A. Cerione

January 1, 1991

Rapid publication TGF‐β1 induces bone closure of skull defects

Journal of Bone and Mineral Research, ISSN: 15234681 08840431

L. Steven Beck; Leo Deguzman; Wyne P. Lee; Yvette Xu; Lorrie L. Mcfatridge; Nancy Gillett; Edward P. Amento

January 1, 1991

Decreased metabolic clearance of endogenous growth hormone and specific alterations in the pulsatile mode of growth hormone secretion occur in prepubertal girls with turner’s syndrome

Journal of Clinical Endocrinology and Metabolism, ISSN: 19457197 0021972X

Johannes D. Veldhuis; Juan F. Sotos; Barry M. Sherman; Ann J. Johanson; Robert M. Blizzard; Barbara M. Lippe; Saenger

January 1, 1991

Cloning and expression of a divergent integrin subunit β8

Journal of Biological Chemistry, ISSN: 00219258

Matthew Moyle; Napier; McLean

January 1, 1991

The complement binding-like domains of the murine homing receptor facilitate lectin activity

Journal of Cell Biology, ISSN: 00219525

Susan R. Watson; Yasuyuki Imai; Christopher Fennie; Joyce Geoffrey; Mark S. Singer; Steven D. Rosen; Lasky

January 1, 1991

Sequence and functional characterization of the human purine nucleoside phosphorylase promoter

Nucleic Acids Research, ISSN: 03051048

Joh J. Jonsson; Steven R. Williams; R.Scott McIvor

January 1, 1991

Thermodynamics of ligand binding and denaturation for his64 mutants of tissue plasminogen activator kringle‐2 domain

Proteins: Structure, Function and Bioinformatics, ISSN: 10970134 08873585

Robert F. Kelley; Abraham M. Devos; Scott Cleary

January 1, 1991

Structure and functional expression of a human interleukin-8 receptor

Science, ISSN: 00368075

William E. Holmes; James Lee; Wun-Jing Kuang; Glenn C. Rice; William I. Wood

January 1, 1991

Cu,Zn superoxide dismutase is a peroxisomal enzyme in human fibroblasts and hepatoma cells

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Gilbert-Andre Keller; Warner; Steimer; Hallewell

January 1, 1991

Thrombin and parathyroid hormone mobilize intracellular calcium in rat osteosarcoma cells by distinct pathways

Endocrinology, ISSN: 19457170 00137227

Michael Babich; Hester Choi; Johnson; King; Gay E. Alford; Robert A. Nissenson

January 1, 1991

In vivo induction of bone by recombinant human transforming growth factor β1

Journal of Bone and Mineral Research, ISSN: 15234681 08840431

L. Steven Beck; Arthur J. Ammann; Thomas B. Aufdemorte; Leo Deguzman; Yvette Xu; Wyne P. Lee; Lorrie L. Mcfatridge; Theresa L. Chen

January 1, 1991

Evolutionary conservation of a microbody targeting signal that targets proteins to peroxisomes, glyoxysomes, and glycosomes

Journal of Cell Biology, ISSN: 00219525

Gilbert-Andre Keller; Skaidrite Krisans; Stephen J. Gould; Sommer; Ching C. Wang; Schliebs; Kunau; Stuart Brody; Suresh Subramani

January 1, 1991

Primary structure and biological activity of human brain-derived neurotrophic factor

Endocrinology, ISSN: 19457170 00137227

Rosenthal; David V. Goeddel; Tue H. Nguyen; Evelyn Martin; Louis E. Burton; Shih; Laramee; Florian M. Wurm; Anthony J. Mason; Nikolics; Winslow

January 1, 1991

Industrial scale harvest of proteins from mammalian cell culture by tangential flow filtration

Biotechnology and Bioengineering, ISSN: 10970290 00063592

Robert Van Reis; Lee C. Leonard; Chung C. Hsu; Stuart E. Builder

January 1, 1991

Engineering and design. Editorial overview

Current Opinion in Structural Biology, ISSN: 0959440X

F. Raymond Salemme; James A. Wells

January 1, 1991

Intravascular IL-8: Inhibitor of polymorphonuclear leukocyte accumulation at sites of acute inflammation

Journal of Immunology, ISSN: 00221767

Daniel H. Hechtman; Myron I. Cybulsky; Henry J. Fuchs; Baker; Gimbrone Jr.

January 1, 1991

Ovarian actions of tumor necrosis factor-α (TNFα): Pleiotropic effects of TNFα on differentiated functions of untransformed swine granulosa cells

Endocrinology, ISSN: 19457170 00137227

Johannes D. Veldhuis; James C. Garmey; Randall J. Urban; Laurence M. Demers; Aggarwal

January 1, 1991

The 16K fragment of prolactin specifically inhibits basal or fibroblast growth factor stimulated growth of capillary endothelial cells

Endocrinology, ISSN: 19457170 00137227

Napoleone Ferrara; Carmen Clapp; Richard Weiner

January 1, 1991

Prevention of HIV-1 IIIB infection in chimpanzees by CD4 immunoadhesin

Nature, ISSN: 00280836

Ward; Capon; Jett; Murthy; Joyce Mordenti; Catherine Lucas; Frie; Alfred M. Prince; Green; Eichberg

January 1, 1991

Effect of recombinant inhibin on androgen synthesis in cultured human thecal cells

Molecular and Cellular Endocrinology, ISSN: 03037207

Hillier; Yong; Peter J. Illingworth; Baird; Ralph H. Schwall; Anthony J. Mason

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