Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 14601 - 14650 OF 15397 RESULTS

April 14, 1989

Characterization of G25K, a GTP-binding protein containing a novel putative nucleotide binding domain

Biochemical and Biophysical Research Communications, ISSN: 10902104 0006291X

Paul G. Polakis; Ralph Snyderman; Tony Evans

April 5, 1989

Are there more tumor necrosis factors?

Journal of the National Cancer Institute, ISSN: 00278874

Michael A. Palladino

April 1, 1989

Stimulus-specific production of cyclooxygenase and lipoxygenase metabolites of arachidonic acid by bovine alveolar macrophages

Inflammation, ISSN: 03603997 15732576

Laegreid; Taylor; Englen; Straub; Silflow; Liggitt; Leid

March 24, 1989

Cloning of a lymphocyte homing receptor reveals a lectin domain

Cell, ISSN: 00928674

Lasky; Mark S. Singer; Ted A. Yednock; Dowbenko; Christopher Fennie; Rodriguez; Nguyen; Scott E. Stachel; Steven D. Rosen

March 1, 1989

Effects of CKS-17, a synthetic retroviral envelope peptide, on cell-mediated immunity in vivo: Immunosuppression, immunogenicity, and relation to immunosuppressive tumor products

Cancer Immunology, Immunotherapy, ISSN: 03407004 14320851

Margaret Nelson; David S. Nelson; George J. Cianciolo; Ralph Snyderman

February 24, 1989

Transmembrane TGF-α precursors activate EGF/TGF-α receptors

Cell, ISSN: 00928674

Rainer Brachmann; Patricia B. Lindquist; Mariko Nagashima; William J. Kohr; Michael T. Lipari; Napier; Rik Derynck

February 15, 1989

Preferential cleavage of amino- and carboxyl-terminal oligopeptides from vasoactive intestinal polypeptide by human recombinant enkephalinase (neutral endopeptidase, EC 3.4.24.11)

Biochemical and Biophysical Research Communications, ISSN: 10902104 0006291X

Edward J. Goetzl; Sunil P. Sreedharan; Christoph W. Turck; Robert L. Bridenbaugh; Bernard Malfroy

February 10, 1989

Functionally distinct G proteins selectively couple different receptors to PI hydrolysis in the same cell

Cell, ISSN: 00928674

Avi Ashkenazi; Ernest G. Peralta; Winslow; Ramachandran; Capon

January 1, 1989

A yeast actin-binding protein is encoded by SAC6, a gene found by suppression of an actin mutation

Science, ISSN: 00368075

Alison E. M. Adams; David Botstein; Drubin

January 1, 1989

Absorption of human growth hormone from the rat lung.

Biotechnology Therapeutics, ISSN: 08982848

John R. Patton; McCabe; Hansen; Daugherty

January 1, 1989

Substrate Specificities of Growth Factor Associated Kallikreins of the Mouse Submandibular Gland

Biochemistry, ISSN: 15204995 00062960

Michael Blaber; Paul J. Isackson; James C. Marsters Jr.; Burnier; Ralph A. Bradshaw

January 1, 1989

Connective tissue metabolism including cytokines

Current Opinion in Rheumatology, ISSN: 10408711

Edward P. Amento

January 1, 1989

Lutropin-choriogonadotropin receptor: An unusual member of the G protein-coupled receptor family

Science, ISSN: 00368075

McFarland; Rolf Sprengel; Phillips; Martin Köhler; Nora Rosemblit; Nikolics; Deborah L. Segaloff; Peter H. Seeburg

January 1, 1989

Rapid Kinetics of α2-Adrenergic Inhibition of Adenylate Cyclase. Evidence for a Distal Rate-Limiting Step

Biochemistry, ISSN: 15204995 00062960

William J. Thomsen; Richard R. Neubig

January 1, 1989

Purification of Recombinant Human Tissue Factor

Biochemistry, ISSN: 15204995 00062960

Lisa R. Paborsky; Keri M. Tate; Reed J. Harris; Yansura; Louise Band; Glynis McCray; Cornelia M. Gorman; Donogh P. O'Brien; Judy H. Chang; James R. Swartz; Victor P. Fung; James N. Thomas; Gordon A. Vehar

January 1, 1989

Fragments of Bovine Insulin-like Growth Factors I and II Stimulate Proliferation of Rat L6 Myoblast Cells

Biochemistry, ISSN: 15204995 00062960

Yasuo Konishi; Claire Kotts; Lea Doerr Bullock; Jacob S. Tou; Debra A. Johnson

January 1, 1989

Generic trans-kingdom sex?

Nature, ISSN: 00280836

Scott E. Stachel; Patricia C. Zambryski

January 1, 1989

Purification and Characterization of Tissue Plasminogen Activator Kringle-2 Domain Expressed in Escherichia coli

Biochemistry, ISSN: 15204995 00062960

Scott Cleary; Michael G. Mulkerrin; Robert F. Kelley

January 1, 1989

The MHC-binding and gpl20-binding functions of CD4 are separable

Science, ISSN: 00368075

Daniel Lamarre; Avi Ashkenazi; Sylvain Fleury; Smith; Rafick-P. Sekaly; Capon

January 1, 1989

Human transforming growth factor-β3: Recombinant expression, purification, and biological activities in comparison with transforming growth factors-β1 and -β2

Molecular Endocrinology, ISSN: 19449917 08888809

Graycar; Duncan A. Miller; Arrick; Lyons; Moses; Rik Derynck

January 1, 1989

Protein Engineering of Disulfide Bonds in Subtilisin BPN'

Biochemistry, ISSN: 15204995 00062960

Colin Mitchinson; James A. Wells

January 1, 1989

Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer

Science, ISSN: 00368075

Dennis J. Slamon; William Godolphin; Lovell A. Jones; John A. Holt; Steven Wong; Duane E. Keith; Wendy J. Levin; Susan G. Stuart; Judy Udove; Axel Ullrich; Michael F. Press

January 1, 1989

Designing CD4 immunoadhesins for AIDS therapy

Nature, ISSN: 00280836

Capon; Steven M. Chamow; Joyce Mordenti; Scot A. Marsters; Timothy Gregory; Hiroaki Mitsuya; Randal A. Byrn; Catherine Lucas; Florian M. Wurm; Jerome E. Groopman; Samuel Broder; Smith

January 1, 1989

Fibroblasts transformed with v-src show enhanced formation of an inositol tetrakisphosphate

Science, ISSN: 00368075

Johnson; Wasilenko; Matringly; Weber; Garrison

January 1, 1989

Peptide-based radioimmunoassay for insulin receptor. Detection of insulin-stimulated downregulation in IM-9 lymphocytes

Diabetes, ISSN: 00121797

McFarland; Ramachandran; Grunfeld

January 1, 1989

Pharmacologic basis for the safety assessment of recombinant human proteins

Journal of the American College of Toxicology, ISSN: 07300913

Cossum

January 1, 1989

Monoclonal Antibodies: Production, Purification, and Technology

Advances in Clinical Chemistry, ISSN: 00652423

David Vetterlein

January 1, 1989

Synthesis of novel polycyclic nucleoside analogues incorporation into oligodeoxynucleotides, and interaction with complementary sequences

Journal of the American Chemical Society, ISSN: 15205126 00027863

Norbert Bischofberger; Matteucci

January 1, 1989

Cloning and expression of the cDNA for the murine interferon γ receptor

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Patrick W. Gray; Leong; Fennie; Farrar; Pingel; Fernandez-Luna; Schreiber

January 1, 1989

A fusion protein required for vesicle-mediated transport in both mammalian cells and yeast

Nature, ISSN: 00280836

Duncan W. Wilson; Celeste A. Wilcox; Gregory C. Flynn; Ellson Y. Chen; Wun-Jing Kuang; William J. Henzel; Marc R. Block; Axel Ullrich; James E. Rothman

January 1, 1989

A common language for physical mapping of the human genome

Science, ISSN: 00368075

Maynard Olson; Leroy Hood; Charles Cantor; David Botstein

January 1, 1989

Engineering subtilisin BPN′ for site‐specific proteolysis

Proteins: Structure, Function and Bioinformatics, ISSN: 10970134 08873585

Paul J. Carter; Björn Nilsson; Burnier; Burdick; James A. Wells

January 1, 1989

Endothelial interleukin-8: A novel inhibitor of leukocyte-endothelial interactions

Science, ISSN: 00368075

Gimbrone Jr.; Obin; Brock; Luis; Hass; Hébert; Yip; Leung; Lowe; William J. Kohr; Darbonne; Bechtol; Baker

January 1, 1989

1H NMR Structural Characterization of a Recombinant Kringle 2 Domain from Human Tissue-Type Plasminogen Activator

Biochemistry, ISSN: 15204995 00062960

In-Ja L. Byeon; Robert F. Kelley; Miguel Llinás

January 1, 1989

Inflammatory destruction of pancreatic β cells in γ-interferon transgenic mice

Cold Spring Harbor Symposia on Quantitative Biology, ISSN: 00917451

Sarvetnick; Shizuru; Liggitt; Stewart

January 1, 1989

Effect of residue 65 substitutions on thermal stability of tissue plasminogen activator kringle-2 domain

Biochemistry, ISSN: 15204995 00062960

Robert F. Kelley; Scott Cleary

January 1, 1989

Amino acid sequence of rubber elongation factor protein associated with rubber particles in Hevea latex.

Journal of Biological Chemistry, ISSN: 00219258

Dennis; William J. Henzel; Bell; William J. Kohr; Light

January 1, 1989

Purification of a prenyltransferase that elongates cis-polyisoprene rubber from the latex of Hevea brasiliensis.

Journal of Biological Chemistry, ISSN: 00219258

Light; Dennis

January 1, 1989

Rubber elongation factor from Hevea brasiliensis. Identification, characterization, and role in rubber biosynthesis.

Journal of Biological Chemistry, ISSN: 00219258

Dennis; Light

January 1, 1989

Rubber elongation by farnesyl pyrophosphate synthases involves a novel switch in enzyme stereospecificity.

Journal of Biological Chemistry, ISSN: 00219258

Light; Lazarus; Dennis

January 1, 1989

Purity analysis of protein pharmaceuticals produced by recombinant DNA technology

Trends in Biotechnology, ISSN: 01677799

Vincent R. Anicetti; Keytand; William S. Hancock

January 1, 1989

Production of human immune interferon by recombinant mammalian cells cultivated on microcarriers

Biotechnology and Bioengineering, ISSN: 10970290 00063592

Smiley; Hu; Daniel I. C. Wang

January 1, 1989

Prevention of the graft-versus-host reaction in newborn mice by antibodies to tumor necrosis factor-alpha

Transplantation, ISSN: 00411337

Shalaby; Brian M. Fendly; Kathleen C. Sheehan; Schreiber; Arthur J. Ammann

January 1, 1989

Analysis of calcium homeostasis in activated human polymorphonuclear leukocytes. Evidence for two distinct mechanisms for lowering cytosolic calcium

Journal of Biological Chemistry, ISSN: 00219258

Axel Perianin; Snydeman

January 1, 1989

Differential activation by atrial and brain natriuretic peptides of two different receptor guanylate cyclases

Nature, ISSN: 00280836

Chang; David G Lowe; Lewis; Renate Hellmiss; Ellson Y. Chen; David V. Goeddel

January 1, 1989

An enzyme-linked immunosorbent assay to study human relaxin in human pregnancy and in pregnant rhesus monkeys

Journal of Endocrinology, ISSN: 00220795

Catherine Lucas; Bald; Martin; Robert B. Jaffe; Drolet; Mora-Worms; Bennett; Chen; Paul D. Johnston

January 1, 1989

Intravenous recombinant tumor necrosis factor in the treatment of aids-related kaposi’s sarcoma

Journal of Acquired Immune Deficiency Syndromes, ISSN: 10779450 15254135

David Aboulafia; Steven A. Miles; Samuel Saks; Ronald T. Mitsuyasu

January 1, 1989

Characterization of a human homologue of the murine peripheral lymph node homing receptor

Journal of Cell Biology, ISSN: 00219525

Bowen; Nguyen; Lasky

January 1, 1989

Recombinant TGF-β1 is synthesized as a two-component latent complex that shares some structural features with the native platelet latent TGF-β1 complex

Growth Factors, ISSN: 08977194

Lalage M. Wakefield; Diane M. Smith; Susan D. Broz; Mark L. Jackson; Levinson; Michael B. Sporn

January 1, 1989

The human cytomegalovirus major immediate early promoter can be trans-activated by adenovirus early proteins

Virology, ISSN: 10960341 00426822

Cornelia M. Gorman; Gies; Glynis McCray; Huang

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