Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 14651 - 14700 OF 15397 RESULTS

January 1, 1989

Expression and secretion of gro/MGSA by stimulated human endothelial cells

EMBO Journal, ISSN: 02614189

Duanzhi Wen; Rowland; Rik Derynck

January 1, 1989

Vgr-1, a mammalian gene related to Xenopus Vg-1, is a member of the transforming growth factor β gene superfamily

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Karen M. Lyons; Graycar; Angela Lee; Hashmi; Patricia B. Lindquist; Ellson Y. Chen; Brigid L.M. Hogan; Rik Derynck

January 1, 1989

Characterization and affinity cross-linking of receptors for human recombinant lymphotoxin (tumor necrosis factor-β) on a human histiocytic lymphoma cell line, U-937

Journal of Biological Chemistry, ISSN: 00219258

Stauber; Aggarwal

January 1, 1989

Intralesional recombinant tumor necrosis factor-a for AIDS-associated kaposis sarcoma: A randomized, double-blind trial

Journal of Acquired Immune Deficiency Syndromes, ISSN: 10779450 15254135

Kahn; Lawrence D. Kaplan; Paul Volberding; John L. Ziegler; Suzanne Crowe; Samuel Saks; Donald Abrams

January 1, 1989

Human atrial natriuretic peptide receptor defines a new paradigm for second messenger signal transduction

EMBO Journal, ISSN: 02614189

David G Lowe; Chang; Renate Hellmiss; Ellson Y. Chen; Singh; Garbers; David V. Goeddel

January 1, 1989

Multiple actions of recombinant activin-a in vivo

Endocrinology, ISSN: 19457170 00137227

Ralph H. Schwall; Charles H. Schmelzer; Matsuyama; Anthony J. Mason

January 1, 1989

The gene encoding GnRH and its associated peptide GAP: Some insights into hypogonadism

Journal of Steroid Biochemistry, ISSN: 00224731

Peter H. Seeburg; Anthony J. Mason; Young III; Stewart; Nikolics

January 1, 1989

Localization of enkephalinase mRNA in rat brain by in situ hybridization: Comparison with immunohistochemical localization of the protein

Neuropeptides, ISSN: 01434179

Josiah N. Wilcox; Pollard; Moreau; Jean-Charles Schwartz; Bernard Malfroy

January 1, 1989

Tau consists of a set of proteins with repeated C-terminal microtubule-binding domains and variable N-terminal domains

Molecular and Cellular Biology, ISSN: 02707306

Himmler; Drechsel; Kirschner; Martin Jr.

January 1, 1989

Characterization of the human growth hormone receptor gene and demonstration of a partial gene deletion in two patients with Laron-type dwarfism

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Godowski; Leung; Meacham; Galgani; Renate Hellmiss; Keret; Rotwein; Parks; Laron; William I. Wood

January 1, 1989

Expression of human plasminogen cDNA in a baculovirus vector-infected insect cell system

Archives of Biochemistry and Biophysics, ISSN: 10960384 00039861

Joann Whitefleet-Smith; Elliot Rosen; James McLinden; Victoria A. Ploplis; Malcolm J. Fraser; James E. Tomlinson; McLean; Francis J. Castellino

January 1, 1989

Cloning of the cDNA of a human neutrophil bactericidal protein. Structural and functional correlations

Journal of Biological Chemistry, ISSN: 00219258

Patrick W. Gray; Gail W. Flaggs; Leong; Gumina; Weiss; Ooi; Elsbach

January 1, 1989

Tumor necrosis factor-α inhibits growth hormone secretion from cultured anterior pituitary cells

Endocrinology, ISSN: 19457170 00137227

Walton; Cronin

January 1, 1989

Identification of the ral and rac1 gene products, low molecular mass GTP-binding proteins from human platelets

Journal of Biological Chemistry, ISSN: 00219258

Paul G. Polakis; Weber; Nevins; Didsbury; Tony Evans; Ralph Snyderman

January 1, 1989

Characterization of human growth hormone by capillary electrophoresis

Journal of Chromatography A, ISSN: 00219673

John Frenz; Shiaw-Lin Wu; William S. Hancock

January 1, 1989

Interferon-gamma in a family with X-linked lymphoproliferative syndrome with acute Epstein-Barr virus infection

Journal of Clinical Immunology, ISSN: 02719142 15732592

Motohiko Okano; Geoffrey M. Thiele; Roger H. Kobayashi; Jack R. Davis; Mark S. Synovec; Helen L. Grierson; Howard S. Jaffe; David T. Purtilo

January 1, 1989

Inhibition of tumor cell growth by interferon-γ is mediated by two distinct mechanisms dependent upon oxygen tension: Induction of tryptophan degradation and depletion of intracellular nicotinamide adenine dinucleotide

Journal of Clinical Investigation, ISSN: 00219738

Aune; Pogue

January 1, 1989

Interleukin 2 responsive lymphocytes in patients with adenosine deaminase deficiency

Clinical Immunology and Immunopathology, ISSN: 00901229

Morton J Cowan; Wayne Smith; Arthur J. Ammann

January 1, 1989

Current status of recombinant cytokines as clinical therapeutics

Drugs of Today, ISSN: 00257656

Howard S. Jaffe; Stephen A. Sherwin

January 1, 1989

The pharmacokinetics and pharmacodynamics of a human relaxin in the mouse pubic symphysis bioassay

Endocrinology, ISSN: 19457170 00137227

Ferraiolo; Cronin; Bakhit; Michael Roth; Chestnut; Lyon

January 1, 1989

p185(HER2) monoclonal antibody has antiproliferative effects in vitro and sensitizes human breast tumor cells to tumor necrosis factor

Molecular and Cellular Biology, ISSN: 02707306

Hudziak; Gail D. Lewis; Marcy Winget; Brian M. Fendly; Shepard; Axel Ullrich

January 1, 1989

Acetylcholine analogue stimulates DNA synthesis in brain-derived cells via specific muscarinic receptor subtypes

Nature, ISSN: 00280836

Avi Ashkenazi; Ramachandran; Capon

January 1, 1989

Downstream processing of proteins: Recent advances

Biotechnology Advances, ISSN: 07349750

John R. Ogez; James C. Hodgdon; Marc P. Beal; Stuart E. Builder

January 1, 1989

Accelerated growth after recombinant human growth hormone treatment of children with chronic renal failure

Journal of Pediatrics, ISSN: 00223476

Vera H. Koch; Barbara M. Lippe; Pauline A. Nelson; M.Ines Boechat; Barry M. Sherman; Richard N. Fine

January 1, 1989

Synthesis of novel polycyclic nucleoside analogs

Nucleosides and Nucleotides, ISSN: 07328311

Norbert Bischofberger; Matteucci

January 1, 1989

Effect of Dose and Immunization Schedule on Immune Response of Baboons to Recombinant Glycoprotein 120 of HIV-1

Journal of Infectious Diseases, ISSN: 15376613 00221899

Anderson; Catherine Lucas; Cari V. Hanson; Londe; Allen Izu; Timothy Gregory; Arthur J. Ammann; Berman; Eichberg

January 1, 1989

Mapping of genes for inhibin subunits α, βA, and βB on human and mouse chromosomes and studies of jsd mice

Genomics, ISSN: 10898646 08887543

Barton; Yang-Feng; Anthony J. Mason; Peter H. Seeburg; Uta Francke

January 1, 1989

Intervening sequence-specific in situ hybridization: detection of the pro-opiomelanocortin gene primary transcript in individual neurons

Molecular Brain Research, ISSN: 0169328X

Robert T. Fremeau Jr.; Dominic J. Autelitano; Mariann Blum; Josiah N. Wilcox; James L. Roberts

January 1, 1989

Purification and characterization of early pregnancy factor from human pregnancy sera

Journal of Biological Chemistry, ISSN: 00219258

Mehta; Eessalu; Aggarwal

January 1, 1989

Effects of bombesin on human small cell lung cancer cells: Evidence for a subset of bombesin non‐responsive cell lines

Journal of Cellular Biochemistry, ISSN: 10974644 07302312

Helen Kado-Fong; Bernard Malfroy

January 1, 1989

Human homologs of two testes-expressed loci on mouse chromosome 17 map to opposite arms of chromosome 6

Genomics, ISSN: 10898646 08887543

Kirsten B. Bibbins; Jen-Yue Tsai; John Schimenti; Sarvetnick; Huda Y. Zoghbi; Peter Goodfellow; Lee M. Silver

January 1, 1989

Competency-based education in thrombolytic therapy: A modular approach

Journal of Cardiovascular Nursing, ISSN: 15505049 08894655

Theresa M. Gaffney

January 1, 1989

Periplasmic secretion of human growth hormone by Escherichia coli

Biochemical Society Transactions, ISSN: 03005127

Chang; Roger Pai; William F. Bennett; Bochner

January 1, 1989

Endogenous retroviruses of continuous cell substrates.

Developments in biological standardization, ISSN: 03015149

Lubiniecki; Dinowitz; Nelson; Wiebe; May; John R. Ogez; Stuart E. Builder

January 1, 1989

A dominant phenocopy of hypopituitarism in transgenic mice resulting from central nervous system synthesis of human growth hormone

Endocrinology, ISSN: 19457170 00137227

Hollingshead; Martin; Pitts; Stewart

January 1, 1989

Cloning and expression of ovine placental lactogen

Molecular Endocrinology, ISSN: 19449917 08888809

Colosi; Thordarson; Renate Hellmiss; Singh; Forsyth; Peter Gluckman; William I. Wood

January 1, 1989

Molecular characterization of a new immunoglobulin superfamily protein with potential roles in opioid binding and cell contact

EMBO Journal, ISSN: 02614189

Peter R. Schofield; McFarland; Hayflick; Josiah N. Wilcox; Cho; Roy; Lee; Loh; Peter H. Seeburg

January 1, 1989

Receptor and antibody epitopes in human growth hormone identified by homolog-scanning mutagenesis

Science, ISSN: 00368075

Cunningham; Jhurani; Ng; James A. Wells

January 1, 1989

Tumor necrosis factor-α as a proliferative signal for an IL-2-dependent T cell line: Strict species specificity of action

Journal of Immunology, ISSN: 00221767

Ranges; Bombara; Aiyer; Glenn C. Rice; Michael A. Palladino

January 1, 1989

Model for intracellular folding of the human immunodeficiency virus type 1 gp120

Journal of Virology, ISSN: 0022538X

Christopher Fennie; Lasky

January 1, 1989

Genomic Cloning and Heterologous Expression of Human Differentiation-Stimulating Factor

DNA, ISSN: 15577430 01980238

David G Lowe; Wylla Nunes; Bombara; McCabe; Ranges; William J. Henzel; Tomida; Yuri Yamamoto-Yamaguchi; Hozumi; David V. Goeddel

January 1, 1989

Chronic therapy with recombinant tumor necrosis factor-α in autoimmune NZB/NZW F1 mice

Clinical Immunology and Immunopathology, ISSN: 00901229

Gordon; Ranges; John S. Greenspan; David Wofsy

January 1, 1989

Cytoplasmic domains determine signal specificity, cellular routing characteristics and influence ligand binding of epidermal growth factor and insulin receptors

EMBO Journal, ISSN: 02614189

Riedel; Dull; Honegger; Schlessinger; Axel Ullrich

January 1, 1989

The Use of α-Aminoboronic Acid Derivatives to Stabilize Peptide Drugs During Their Intranasal Absorption

Pharmaceutical Research, ISSN: 1573904X 07248741

Munir A. Hussain; Ashok B. Shenvi; Susan M. Rowe; Eli Shefter

January 1, 1989

Purification and characterization of recombinant human parathyroid hormone-related protein

Journal of Biological Chemistry, ISSN: 00219258

R. Glenn Hammonds; McKay; Winslow; Diefenbach-Jagger; Grill; Glatz; Rodda; Moseley; William I. Wood; Martin

January 1, 1989

Chromosome mapping of the growth hormone receptor gene in man and mouse

Cytogenetic and Genome Research, ISSN: 1424859X 14248581

Barton; Foellmer; Woodland; Uta Francke

January 1, 1989

The primary structure of a protein carboxyl methyltransferase from bovine brain that selectively methylates L-isoaspartyl sites

Journal of Biological Chemistry, ISSN: 00219258

William J. Henzel; Stults; Hsu; Aswad

January 1, 1989

Analysis of the signal for attachment of a glycophospholipid membrane anchor

Journal of Cell Biology, ISSN: 00219525

Caras; Weddell; Steven R. Williams

January 1, 1989

Variability in the quantitation of circulating growth hormone using commercial immunoassays

Journal of Clinical Endocrinology and Metabolism, ISSN: 19457197 0021972X

Abbie Celniker; Chen; Wert Jr.; Barry M. Sherman

January 1, 1989

HER2 cytoplasmic domain generates normal mitogenic and transforming signals in a chimeric receptor

EMBO Journal, ISSN: 02614189

James Lee; Dull; Lax; Schlessinger; Axel Ullrich

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