Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 14751 - 14800 OF 15397 RESULTS

November 1, 1988

Inhibitors of Cyclic AMP Phosphodiesterase. 4. Synthesis and Evaluation of Potential Prodrugs of Lixazinone (N-Cyclohexyl-N-methyl-4-[(1,2,3,5-tetrahydro-2-oxoimidazo[2,1-b]quinazolin-7-yl)-oxy]butyramide, RS-82856)

Journal of Medicinal Chemistry, ISSN: 15204804 00222623

Michael C. Venuti; Robert Alvarez; John J. Bruno; Arthur M. Strosberg; Leo Gu; Hi-Shi Chiang; Ian J. Massey; Nancy Chu; John H. Fried

November 1, 1988

Topical Nonsteroidal Antipsoriatic Agents. 2. 2,3-(Alkylidenedioxy)naphthalene Analogues of Lonapalene

Journal of Medicinal Chemistry, ISSN: 15204804 00222623

Michael C. Venuti; Brad E. Loe; Gordon H. Jones; John M. Young

November 1, 1988

Inhibitors of Cyclic AMP Phosphodiesterase. 3. Synthesis and Biological Evaluation of Pyrido and Imidazolyl Analogues of 1,2,3,5-Tetrahydro-2-oxoimidazo[2,1-b]quinazoline

Journal of Medicinal Chemistry, ISSN: 15204804 00222623

Michael C. Venuti; Robert A. Stephenson; Robert Alvarez; John J. Bruno; Arthur M. Strosberg

October 4, 1988

Enzyme-linked immunosorbent assays (ELISAs) for the determination of contaminants resulting from the immunoaffinity purification of recombinant proteins

Journal of Immunological Methods, ISSN: 00221759

Catherine Lucas; Nelson; Peterson; Frie; David Vetterlein; Timothy Gregory; Chen

September 30, 1988

Analysis of nucleotide sequences of two ligninase cDNAs from a white-rot filamentous fungus, Phanerochaete chrysosporium

Gene, ISSN: 03781119

Herman A. de Boer; Zhang; Collins; C.Adinarayana Reddy

September 26, 1988

The nucleotide sequence for the cDNA of bovine interleukin-1 alpha

Nucleic Acids Research, ISSN: 03051048

Leong; Gail W. Flaggs; Lawman; Patrick W. Gray

September 26, 1988

The nucleotide sequence for the cDNA of bovine interleukin-1 beta

Nucleic Acids Research, ISSN: 03051048

Leong; Gail W. Flaggs; Lawman; Patrick W. Gray

September 1, 1988

Resistance of tumor cells to tumor necrosis factor

Journal of Clinical Immunology, ISSN: 02719142 15732592

Shepard; Gail D. Lewis

August 26, 1988

Mutation of the insulin receptor at tyrosine 960 inhibits signal transmission but does not affect its tyrosine kinase activity

Cell, ISSN: 00928674

Morris F. White; James N. Livingston; Jonathan M. Backer; Vilma Lauris; Dull; Axel Ullrich; C. Ronald Kahn

August 26, 1988

Transforming growth factor α

Cell, ISSN: 00928674

Rik Derynck

August 17, 1988

Transplantation resistance to a rous sarcoma virus-induced tumor in mice immunized with v-src protein

Journal of the National Cancer Institute, ISSN: 00278874

Noboru Kuzumaki; Hisakazu Fujita; Hirotoshi Dosaka; Motoo Katabami; Levinson

August 15, 1988

Purification and characterization of the restriction endonuclease RsrI, an isoschizomer of EcoRI

Gene, ISSN: 03781119

Patricia J. Greene; Barry T. Ballard; Frank Stephenson; William J. Kohr; Rodriguez; John M. Rosenberg; Herbert W. Boyer

August 12, 1988

Analysis of host-virus interactions in AIDS with anti-gp120 T cell clones: Effect of HIV sequence variation and a mechanism for CD4+ cell depletion

Cell, ISSN: 00928674

Robert F. Siliciano; Trebor Lawton; Cindy Knall; Robert W. Karr; Berman; Timothy Gregory; Ellis L. Reinherz

August 1, 1988

The apolipoprotein(a) gene resides on human chromosome 6q26-27, in close proximity to the homologous gene for plasminogen

Human Genetics, ISSN: 03406717 14321203

Susan Lynn Frank; Ivana Klisak; Robert S. Sparkes; Mohandas; James E. Tomlinson; McLean; Lawn; Aldons J. Lusis

August 1, 1988

Tolerance and efficacy of recombinant human interferon gamma in the treatment of refractory genital warts

American Journal of Medicine, ISSN: 00029343

Philip K. Kirby; Nancy Kiviat; Ann Beckman; Denise Wells; Stephen A. Sherwin; Lawrence Corey

August 1, 1988

ANALYTICAL AND PROCESS CHROMATOGRAPHY IN PHARMACEUTICAL PROTEIN PRODUCTION.

Chemical Engineering Progress, ISSN: 03607275

Stuart E. Builder; William S. Hancock

July 1, 1988

1-(2,3-anhydro-β-D-lyxofuranosyl)cytosine derivatives as Potential Inhibitors of the Human Immunodeficiency Virus

Journal of Medicinal Chemistry, ISSN: 15204804 00222623

Thomas R. Webb; Hiroaki Mitsuya; Samuel Broder

June 24, 1988

A new Sst 1 RFLP associated with human insulin receptor locus

Nucleic Acids Research, ISSN: 03051048

Patel; O'Rahilly; Axel Ullrich; Turner; Wainscoat

June 10, 1988

Phosphoramidate analogues of DNA: Synthesis and thermal stability of heteroduplexes

Nucleic Acids Research, ISSN: 03051048

Froehler; Ng; Matteucci

May 1, 1988

Isolation, Cloning, and Sequencing of the Salmonella typhimurium ddlA Gene with Purification and Characterization of Its Product, D-Alanine:D-Alanine Ligase (ADP Forming)

Biochemistry, ISSN: 15204995 00062960

Elisabeth Daub; Laura E. Zawadzke; David Botstein; Christopher Walsh

April 1, 1988

Binding of α2-Macroglobulin-Thrombin Complexes and Methylamine-Treated α2-Macroglobulin to Human Blood Monocytes

Biochemistry, ISSN: 15204995 00062960

David L. Straight; Laszlo Jakoi; Patrick A. McKee; Ralph Snvderman

April 1, 1988

Suppression of immune cell function in vitro by recombinant human transforming growth factor-β

Cellular Immunology, ISSN: 10902163 00088749

Shalaby; Arthur J. Ammann

April 1, 1988

Tumor necrosis factor α/cachectin is a growth factor for thymocytes: Synergistic interactions with other cytokines

Journal of Experimental Medicine, ISSN: 15409538 00221007

Ranges; Albert Zlotnik; Espevik; Dinarello; Cerami; Michael A. Palladino

March 30, 1988

Activin stimulates secretion of follicle-stimulating hormone from pituitary cells desensitized to gonadotropin-releasing hormone

Biochemical and Biophysical Research Communications, ISSN: 10902104 0006291X

Ralph H. Schwall; Szonyi; Anthony J. Mason; Nikolics

March 11, 1988

Insulin-dependent diabetes mellitus induced in transgenic mice by ectopic expression of class II MHC and interferon-gamma

Cell, ISSN: 00928674

Sarvetnick; Liggitt; Pitts; Hansen; Stewart

March 11, 1988

Expression of the plasmid-encoded type I dihydrofolate reductase gene in cultured mammalian cells: A novel selectable marker

Nucleic Acids Research, ISSN: 03051048

Simonsen; Walter; Levinson

March 1, 1988

Photoaffinity Labeling of Pituitary GnRH Receptors: Significance of the Position of Photolabel on the Ligand

Biochemistry, ISSN: 15204995 00062960

Nikolics; Szonyi; Ramachandran

March 1, 1988

Immunopathogenesis of pediatric acquired immunodeficiency syndrome.

Journal of Perinatology, ISSN: 07438346

Arthur J. Ammann

February 29, 1988

Molecular cloning and amino acid sequence of human enkephalinase (neutral endopeptidase)

FEBS Letters, ISSN: 00145793

Bernard Malfroy; Wun-Jing Kuang; Peter H. Seeburg; Anthony J. Mason; Peter R. Schofield

February 15, 1988

Co-localization of the nerve growth factor precursor protein and mRNA in the mouse submandibular gland

Neuroscience Letters, ISSN: 03043940

Eleni Dicou; James Lee; Philippe Brachet

February 1, 1988

The determination of recombinant human tissue-type plasminogen activator activity by turbidimetry using a microcentrifugal analyzer

Analytical Biochemistry, ISSN: 10960309 00032697

Ronald H. Carlson; Robert L. Garnick; Andrew J.S. Jones; Meunier

January 1, 1988

Mutagenesis at the mRNA decoding site in the 16S ribosomal RNA using the specialized ribosome system in Escherichia coli.

EMBO Journal, ISSN: 02614189

Hui; Eaton; Herman A. de Boer

January 1, 1988

Approaches to nonradiometric assays for inhibin and activin.

Progress in clinical and biological research, ISSN: 03617742

Ralph H. Schwall; Bald; Szonyi; Anthony J. Mason; Nikolics

January 1, 1988

Lympotoxin and tumor necrosis factor influenced the B cell proliferation and differentiation in vitro

International Journal of Immunopharmacology, ISSN: 01920561

Morikawa; Shepart; Michael A. Palladino; Cooper

January 1, 1988

Epitope mapping of the human immunodeficiency virus type 1 gp120 with monoclonal antibodies

Journal of Virology, ISSN: 0022538X

Dowbenko; Nakamura; Christopher Fennie; Shimasaki; Riddle; Reed J. Harris; Timothy Gregory; Lasky

January 1, 1988

Plasminogen Activators

Annual Reports in Medicinal Chemistry, ISSN: 00657743

Ross; Grossbard; Adair Hotchkiss

January 1, 1988

HIV-infected cells are killed by rCD4-ricin A chain

Science, ISSN: 00368075

Mark A. Till; Victor Ghetie; Timothy Gregory; Patzer; James P. Porter; Jonathan W. Uhr; Capon; Ellen S. Vitetta

January 1, 1988

Sequence and functional expression of the GABAA receptor shows a ligand-gated receptor super-family

Nature, ISSN: 00280836

Peter R. Schofield; Mark G. Darlison; Norihisa Fujita; David R. Burt; F. Anne Stephenson; Rodriguez; Lucy M. Rhee; Ramachandran; Vincenzina Reale; Thora A. Glencorse; Peter H. Seeburg; Eric A. Barnard

January 1, 1988

A single receptor binds both insulin-like growth factor II and mannose-6-phosphate

Science, ISSN: 00368075

Richard G. Macdonald; Suzanne R. Pfeffer; Lisa Coussens; Mark A. Tepper; Carol M. Brocklebank; John E. Mole; Jacqueline K. Anderson; Ellson Y. Chen; Michael P. Czech; Axel Ullrich

January 1, 1988

Chromosomal mapping of the gene for the type II insulin-like growth factor receptor/cation-independent mannose 6-phosphate receptor in man and mouse

Genomics, ISSN: 10898646 08887543

Geneviève Laureys; Barton; Axel Ullrich; Uta Francke

January 1, 1988

Recombinant expression and characterization of human activin a

Molecular Endocrinology, ISSN: 19449917 08888809

Ralph H. Schwall; Nikolics; Szonyi; Cornelia M. Gorman; Anthony J. Mason

January 1, 1988

Yeast: An experimental organism for modern biology

Science, ISSN: 00368075

David Botstein; Gerald R. Fink

January 1, 1988

Dissecting the catalytic triad of a serine protease

Nature, ISSN: 00280836

Paul J. Carter; James A. Wells

January 1, 1988

Subtilisin - an enzyme designed to be engineered

Trends in Biochemical Sciences, ISSN: 09680004

James A. Wells; David A. Estell

January 1, 1988

Antenatal serum levels of relaxin in patients having preterm labour

British Journal of Obstetrics and Gynaecology, ISSN: 14710528 14700328

Robin J. Bell; Lawrence W. Eddie; Arlene R. Lester; E.Carl Wood; Paul D. Johnston; Hugh D. Niall

January 1, 1988

Membrane guanylate cyclase is a cell-surface receptor with homology to protein kinases

Nature, ISSN: 00280836

Singh; David G Lowe; David S. Thorpe; Rodriguez; Wun-Jing Kuang; Lawrence J. Dangott; Michael Chinkers; David V. Goeddel; Garbers

January 1, 1988

Tertiary structure is a principal determinant to protein deamidaton

Science, ISSN: 00368075

Anthony A. Kossiakoff

January 1, 1988

Production and auto-induction of transforming growth factor-α in human keratinocytes

Nature, ISSN: 00280836

Robert J. Coffey; Rik Derynck; Josiah N. Wilcox; Timothy S. Bringman; A. Scott Goustin; Moses; Mark R. Pittelkow

January 1, 1988

Structural and functional basis for GABAA receptor heterogeneity

Nature, ISSN: 00280836

Edwin S. Levitan; Peter R. Schofield; David R. Burt; Lucy M. Rhee; William Wisden; Martin Köhler; Norihisa Fujita; Rodriguez; Anne Stephenson; Mark G. Darlison; Eric A. Barnard; Peter H. Seeburg

January 1, 1988

Protein products from yeast.

Biochemical Society Transactions, ISSN: 03005127

Ronald A. Hitzeman; Chung N. Chang; Christina Y. Chen; Arjun Singh; Etcheverry; Chisholm; William J. Kohr; Gordon A. Vehar; Renz; Dowbenko

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