Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 14801 - 14850 OF 15397 RESULTS

January 1, 1988

Cloning and expression of the growth hormone-dependent insulin-like growth factor-binding protein

Molecular Endocrinology, ISSN: 19449917 08888809

William I. Wood; Cachianes; William J. Henzel; Genine Winslow; Steven A. Spencer; Renate Hellmiss; Martin; Baxter

January 1, 1988

Human immunodeficiency virus infections in infants and children.

Advances in pediatric infectious diseases, ISSN: 08849404

Arthur J. Ammann

January 1, 1988

The use of neutrons to show how proteins work.

Basic life sciences, ISSN: 00905542

Anthony A. Kossiakoff

January 1, 1988

A new type of transforming growth factor-beta, TGF-beta 3.

EMBO Journal, ISSN: 02614189

Rik Derynck; Patricia B. Lindquist; Angela Lee; Duanzhi Wen; Tamm; Graycar; Lucy M. Rhee; Anthony J. Mason; Duncan A. Miller; Robert J. Coffey

January 1, 1988

Functional role of muscarinic acetylcholine receptor subtype diversity

Cold Spring Harbor Symposia on Quantitative Biology, ISSN: 00917451

Avi Ashkenazi; Ernest G. Peralta; Winslow; Ramachandran; Capon

January 1, 1988

Localization of Bacillus subtilis sacU(Hy) mutations to two linked genes with similarities to the conserved procaryotic family of two-component signalling systems.

Journal of Bacteriology, ISSN: 00219193

Henner; Yang; Ferrari

January 1, 1988

Multiple early transcripts and splicing of the Autographa californica nuclear polyhedrosis virus IE-1 gene.

Journal of Virology, ISSN: 0022538X

Chisholm; Henner

January 1, 1988

Active immunoglobulin fragments synthesized in E.Coti—from Fab to scantibodies

Protein Engineering, ISSN: 17410134 17410126

Wetzel

January 1, 1988

Amplified expression of the HER2/ERBB2 oncogene induces resistance to tumor necrosis factor alpha in NIH 3T3 cells.

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Hudziak; Gail D. Lewis; Shalaby; Eessalu; Aggarwal; Axel Ullrich; Shepard

January 1, 1988

The three-dimensional structure of Bacillus amyloliquefaciens subtilisin at 1.8 A and an analysis of the structural consequences of peroxide inactivation.

Journal of Biological Chemistry, ISSN: 00219258

Bott; Ultsch; Anthony A. Kossiakoff; Graycar; Katz; Power

January 1, 1988

Rabbit liver growth hormone receptor and serum binding protein. Purification, characterization, and sequence.

Journal of Biological Chemistry, ISSN: 00219258

Steven A. Spencer; R. Glenn Hammonds; William J. Henzel; Rodriguez; Michael J. Waters; William I. Wood

January 1, 1988

Signal transduction in cells following binding of chemoattractants to membrane receptors

Virchows Archiv B Cell Pathology Including Molecular Pathology, ISSN: 03406075

Susan B. Dillon; Margrith W. Verghese; Ralph Snyderman

January 1, 1988

The human transforming growth factor alpha promoter directs transcription initiation from a single site in the absence of a TATA sequence

Molecular and Cellular Biology, ISSN: 02707306

Jakobovitis; Schlokat; Vannice; Rik Derynck; Levinson

January 1, 1988

Pharmacokinetics and tissue distribution of recombinant human tumor necrosis factor-α in mice

Drug Metabolism and Disposition, ISSN: 00909556

Ferraiolo; Moore; Crase; Gribling; Wilking; Baughman

January 1, 1988

Factor VIII-bypassing activity of bovine tissue factor using the canine hemophilic model

Journal of Clinical Investigation, ISSN: 00219738

Donogh P. O'Brien; Giles; Keri M. Tate; Gordon A. Vehar

January 1, 1988

Platelet-derived growth factor mRNA detection in human atherosclerotic plaques by in situ hybridization

Journal of Clinical Investigation, ISSN: 00219738

Josiah N. Wilcox; Smith; Williams; Schwartz; Gordon

January 1, 1988

Biodisposition and catabolism of tissue-type plasminogen activator in rats and rabbits

Fibrinolysis and Proteolysis, ISSN: 02689499

Bakhit; Derf A. Lewis; Busch; Tanswell; Mohler

January 1, 1988

Expression of membrane-associated and secreted variants of gp160 of human immunodeficiency virus type 1 in vitro and in continuous cell lines

Journal of Virology, ISSN: 0022538X

Berman; Nunes; Haffar

January 1, 1988

Efficacy of recombinant glycoprotein d subunit vaccines on the development of primary, recurrent, and latent genital infections with herpes simplex virus type 2 in guinea pigs

Journal of Infectious Diseases, ISSN: 15376613 00221899

Vogt; Timothy Gregory; Lasky; Kern; Berman

January 1, 1988

High-level expression of c-H-ras1 fails to fully transform rat-1 cells

Molecular and Cellular Biology, ISSN: 02707306

Ricketts; Levinson

January 1, 1988

Three-year results of a randomized prospective trial of methionyl human growth hormone and oxandrolone in Turner syndrome

Journal of Pediatrics, ISSN: 00223476

Rosenfeld; Hintz; Ann J. Johanson; Barry M. Sherman; Jo Anne Brasel; Stephen Burstein; Chernausek; Peter G. Compton; James W. Frane; Ronald W. Gotlin; Joyce Kuntze; Barbara M. Lippe; Patrick C. Mahoney; Wayne V. Moore; Maria I. New; Saenger; Virginia Sybert

January 1, 1988

Circulatory metabolism of recombinant tissue-type plasminogen activator in monkeys and rabbits

Fibrinolysis and Proteolysis, ISSN: 02689499

Mohler; Keri M. Tate; Timothy S. Bringman; Fuller; Keyt; Gordon A. Vehar; Adair Hotchkiss

January 1, 1988

Developmental expression of transforming growth factors alpha and beta in mouse fetus

Molecular and Cellular Biology, ISSN: 02707306

Josiah N. Wilcox; Rik Derynck

January 1, 1988

Improved Buccal Delivery of Opioid Analgesics and Antagonists with Bitterless Prodrugs

Pharmaceutical Research, ISSN: 1573904X 07248741

Munir A. Hussain; Bruce J. Aungst; Christopher A. Koval; Eli Shefter

January 1, 1988

In vivo anti-tumour activity of recombinant human tumour necrosis factor-alpha against Meth-A sarcoma requires L3T4-positive T cells

Annales de l'Institut Pasteur. Immunologie, ISSN: 07692625

Michael A. Palladino; Figari

January 1, 1988

Differential regulation of PI hydrolysis and adenylyl cyclase by muscarinic receptor subtypes

Nature, ISSN: 00280836

Ernest G. Peralta; Avi Ashkenazi; Winslow; Ramachandran; Capon

January 1, 1988

Role of the red blood cell in drug metabolism

Biopharmaceutics and Drug Disposition, ISSN: 1099081X 01422782

Cossum

January 1, 1988

Decreased locomotor activity produced by repeated, but not single, administration of murine-recombinant interferon-gamma in mice

Life Sciences, ISSN: 00243205

Susan B. Weinberger; Gery Schulteis; April G. Fernando; Bakhit; Joe L. Martinez Jr.

January 1, 1988

Equivalent potency and pharmacokinetics of recombinant human growth hormones with or without an n-terminal methionine

Endocrinology, ISSN: 19457170 00137227

Moore; Rudman; MacLachlan; Fuller; Belinda Burnett; James W. Frane

January 1, 1988

The direct conversion of 5′-O-trityl-3′-keto-2′-deoxythymidine to 1-(2-deoxy-3-methyl-beta-D-xylosyl)thymine

Tetrahedron Letters, ISSN: 00404039

Thomas R. Webb

January 1, 1988

Human immunodeficiency virus type 1 challenge of chimpanzees immunized with recombinant envelope glycoprotein gp120

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Berman; Jerome E. Groopman; Timothy Gregory; Clapham; Weiss; Ferriani; Riddle; Shimasaki; Catherine Lucas; Lasky; Eichberg

January 1, 1988

Multiple regulatory domains in the mouse mammary tumor virus long terminal repeat revealed by analysis of fusion genes in transgenic mice.

Molecular and Cellular Biology, ISSN: 02707306

Stewart; Hollingshead; Pitts

January 1, 1988

Technology unlimited—hoisted on our own petard

Journal of the Canadian Society of Forensic Science, ISSN: 00085030

Bryan S Finkle

January 1, 1988

Genetic linkage between lipoprotein(a) phenotype and a DNA polymorphism in the plasminogen gene

Genomics, ISSN: 10898646 08887543

Drayna; Robert A. Hegele; Hass; Mitsuru Emi; Lily L. Wu; Dan L. Eaton; Lawn; Roger R. Williams; Ray L. White; Jean-Marc Lalouel

January 1, 1988

Properties of the human hepatitis B virus enhancer: Position effects and cell-type nonspecificity

Journal of Virology, ISSN: 0022538X

Vannice; Levinson

January 1, 1988

Pharmacokinetics of Recombinant Murine Interferon-γ and Human Interferon-αA/D(Bgl) Administered in Concert and Their Influence on Natural Killer Cell Function in Mice

Journal of Interferon Research, ISSN: 15577465 01978357

Chen; Shalaby; Crase; Michael A. Palladino; Baughman

January 1, 1988

In vitro anti-human immunodeficiency virus activities of tumor necrosis factor-α and interferon-γ

Journal of Immunology, ISSN: 00221767

Grace H.W. Wong; Krowka; Stites; David V. Goeddel

January 1, 1988

Molecular cloning of the cDNA for a mutant mouse ribonucleotide reductase M1 that produces a dominant mutator phenotype in mammalian cells

Molecular and Cellular Biology, ISSN: 02707306

Caras; Martin Jr.

January 1, 1988

Topogenic analysis of the human immunodeficiency virus type 1 envelope glycoprotein, gp160, in microsomal membranes

Journal of Cell Biology, ISSN: 00219525

Haffar; Dowbenko; Berman

January 1, 1988

Short communication: Pharmacokinetics of recombinant human interferon-gamma in the rhesus monkey after intravenous, intramuscular, and subcutaneous administration

Journal of Biological Response Modifiers, ISSN: 07326580

Ferraiolo; Fuller; Belinda Burnett; Elton Chan

January 1, 1988

Specificity of tyrosine protein kinases of the structurally related receptors for insulin and insulin-like growth factor I: Tyr-containing synthetic polymers as specific inhibitors or substrates

Archives of Biochemistry and Biophysics, ISSN: 10960384 00039861

Dinkar Sahal; Ramachandran; Yoko Fujita-Yamaguchi

January 1, 1988

A discrete element 3' of human immunodeficiency virus 1 (HIV-1) and HIV-2 mRNA initiation sites mediates transcriptional activation by an HIV trans activator

Molecular and Cellular Biology, ISSN: 02707306

Jacobovits; Smith; Jakobovits; Capon

January 1, 1988

Enhancement of a secondary antibody response to vesicular stomatitis virus 'G' protein by IFN-γ treatment at primary immunization

Journal of Immunology, ISSN: 00221767

Anderson; Fennie; Yilma

January 1, 1988

Reduced mortality in murine cytomegalovirus infected mice following prophylactic murine interferon-γ treatment

Antiviral Research, ISSN: 01663542

Fennie; Yolanda S. Lie; Mari-Anne L. Low; Gribling; Anderson

January 1, 1988

Characterization of the in Vitro and in Vivo Species Preference of Human and Murine Tumor Necrosis Factor-a

Cancer Research, ISSN: 15387445 00085472

Susan M. Kramer; Aggarwal; Eessalu; McCabe; Ferraiolo; Figari; Michael A. Palladino

January 1, 1988

New medicines from industry

Journal of Chemical Technology and Biotechnology, ISSN: 10974660 02682575

Bryan S Finkle

January 1, 1988

The structural gene for the M1 subunit of ribonucleotide reductase maps to chromosome 11, band p15, in human and to chromosome 7 in mouse

Experimental Cell Research, ISSN: 00144827

Brissenden; Caras; Thelander; Uta Francke

January 1, 1988

Quantitation of urinary growth hormone in children with normal and abnormal growth

Pediatric Research, ISSN: 15300447 00313998

Christine H. Albini; Teresa Quattrin; Richard L. Vandlen; Margaret H. Macgillivray

January 1, 1988

Localization of cells synthesizing transforming growth factor-alpha mRNA in the mouse brain

Journal of Neuroscience, ISSN: 02706474

Josiah N. Wilcox; Rik Derynck

January 1, 1988

A point mutation in the last intron responsible for increased expression and transforming activity of the c-Ha-ras oncogene

Nature, ISSN: 00280836

Justus B. Cohen; Levinson

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