Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 15101 - 15150 OF 15397 RESULTS

January 1, 1986

In Vitro Biological Activities of Escherichia Coli-Derived Bovine Interferons-α, -β, and -γ

Journal of Interferon Research, ISSN: 15577465 01978357

Christine W. Czarniecki; Hamilton; Christopher Fennie; Ronald L. Wolf

January 1, 1986

Large-scale cell culture in biotechnology

Science, ISSN: 00368075

W. Robert Arathoon; Birch

January 1, 1986

Probing steric and hydrophobic effects on enzyme-substrate interactions by protein engineering

Science, ISSN: 00368075

David A. Estell; Graycar; Jeffrey V. Miller; Powers; Burnier; Ng; James A. Wells

January 1, 1986

Cell culture derived recombinant hbsag is highly immunogenic and protects chimpanzees from infection with hepatitis B virus

Bio/Technology, ISSN: 0733222X

Patzer; Nakamura; Robert D. Hershberg; Timothy Gregory; Crowley; Levinson; Eichberg

January 1, 1986

Serodiagnosis of antibodies to the human aids retrovirus with a bacterially synthesized ehv polypeptide

Bio/Technology, ISSN: 0733222X

Cirilo D. Cabradilla Jr.; Jerome E. Groopman; Joan Lanigan; Renz; Lasky; Capon

January 1, 1986

1. Primary Structure of Insulin and Insulin-like Growth Factor I Receptors

Journal of the Japan Diabetes Society, ISSN: 0021437X

Axel Ullrich; Gray; Collins; Ellson Y. Chen; TSUBOKAWA; Steven Jacobs; Yoko Fujita-Yamaguchi

December 17, 1985

Urea treatment allows dithiothreitol to release the binding subunit of the insulin receptor from the cell membrane: Implications for the structural organization of the insulin receptor

Biochemical and Biophysical Research Communications, ISSN: 10902104 0006291X

Grunfeld; Judy Kwan Shigenaga; Ramachandran

December 1, 1985

Nucleic acid structure and expression of the human AIDS/lymphadenopathy retrovirus

Nature, ISSN: 00280836

Mark A. Muesing; Smith; Cirilo D. Cabradilla Jr.; Charles V. Benton; Lasky; Capon

December 1, 1985

A phase I trial of recombinant gamma interferon in patients with cancer

Cancer Immunology, Immunotherapy, ISSN: 03407004 14320851

Kenneth A. Foon; Stephen A. Sherwin; Paul G. Abrams; Henry C. Stevenson; Pamela Holmes; Annette E. Maluish; Robert K. Oldham; Ronald B. Herberman

December 1, 1985

Activation of human polymorphonuclear neutrophil functions by interferon-γ and tumor necrosis factors

Journal of Immunology, ISSN: 00221767

Shalaby; Aggarwal; Rinderknecht; Svedersky; Bryan S Finkle; Michael A. Palladino

December 1, 1985

Topology of signal recognition particle receptor in endoplasmic reticulum membrane

Nature, ISSN: 00280836

Leander Lauffer; Pablo D. Garcia; Harkins; Lisa Coussens; Axel Ullrich; Peter Walter

December 1, 1985

Human transforming growth factor-β complementary DNA sequence and expression in normal and transformed cells

Nature, ISSN: 00280836

Rik Derynck; Jarrett; Ellson Y. Chen; Eaton; Bell; Richard K. Assoian; Anita B. Roberts; Michael B. Sporn; David V. Goeddel

December 1, 1985

Cloning and expression in Escherichia coli of the cDNA for murine tumor necrosis factor

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Diane Pennica; Hayflick; Timothy S. Bringman; Michael A. Palladino; David V. Goeddel

December 1, 1985

Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin

Nature, ISSN: 00280836

Towia A. Libermann; Harris R. Nusbaum; Nissim Razon; Richard Kris; Lax; Hermona Soreq; Nigel Whittle; Waterfield; Axel Ullrich; Schlessinger

December 1, 1985

Immunocytochemical localization in rat brain of a prolactin release-inhibiting sequence of gonadotropin-releasing hormone prohormone

Nature, ISSN: 00280836

Phillips; Nikolics; Dale Branton; Peter H. Seeburg

December 1, 1985

Distribution of factor VIII MRNA and antigen in human liver and other tissues

Nature, ISSN: 00280836

Karen L. Wion; Deirdre Kelly; Summerfield; Tuddenham; Lawn

December 1, 1985

Characterization of specific high affinity receptors for human tumor necrosis factor on mouse fibroblasts

Journal of Biological Chemistry, ISSN: 00219258

Hass; Adair Hotchkiss; Mohler; Aggarwal

December 1, 1985

Characterization of receptors for human tumour necrosis factor and their regulation by γ-interferon

Nature, ISSN: 00280836

Aggarwal; Eessalu; Hass

December 1, 1985

Human transforming growth factor-α causes precocious eyelid opening in newborn mice

Nature, ISSN: 00280836

Joseph M. Smith; Michael B. Sporn; Anita B. Roberts; Rik Derynck; Winkler; Harry Gregory

December 1, 1985

Bacterial expression of the acquired immunodeficiency syndrome retrovirus p24 gag protein and its use as a diagnostic reagent

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Dowbenko; Bell; Charles V. Benton; Jerome E. Groopman; Nguyen; David Vetterlein; Capon; Lasky

December 1, 1985

HEAT MANAGEMENT IN FERMENTATION PROCESSES.

Princ of Biotechnol, Eng Consid,

Swartz

December 1, 1985

Complementary DNA sequences of ovarian follicular fluid inhibin show precursor structure and homology with transforming growth factor-β

Nature, ISSN: 00280836

Anthony J. Mason; Hayflick; Nicholas Ling; Esch; Naoto Ueno; Shao-Yao Ying; Roger Guillemin; Hugh D. Niall; Peter H. Seeburg

December 1, 1985

Effect of interleukin 2, interferon-γ, and mitogens on the production of tumor necrosis factors α and β

Journal of Immunology, ISSN: 00221767

Nedwin; Svedersky; Timothy S. Bringman; Michael A. Palladino; David V. Goeddel

December 1, 1985

Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes

Nature, ISSN: 00280836

Axel Ullrich; Bell; Ellson Y. Chen; Herrera; Petruzzelli; Dull; Gray; Lisa Coussens; Yu-Cheng Liao; TSUBOKAWA; Anthony J. Mason; Peter H. Seeburg; Grunfeld; Rosen; Ramachandran

December 1, 1985

Genetic mapping and diagnosis of haemophilia A achieved through a BclI polymorphism in the factor VIII gene

Nature, ISSN: 00280836

Jane Gitschier; Drayna; Tuddenham; Ray L. White; Lawn

December 1, 1985

A prolactin-inhibiting factor within the precursor for human gonadotropin-releasing hormone

Nature, ISSN: 00280836

Nikolics; Anthony J. Mason; Éva Sznyi; Ramachandran; Peter H. Seeburg

November 13, 1985

Cloned mouse ribonucleotide reductase subunit M1 cDNA reveals amino acid sequence homology with Escherichia coli and herpesvirus ribonucleotide reductases

Journal of Biological Chemistry, ISSN: 00219258

Caras; Levinson; Fabry; Steven R. Williams; Martin Jr.

October 30, 1985

Defining the borders of the chicken proto-fps gene, a precursor of Fujinami sarcoma virus

Virology, ISSN: 10960341 00426822

Samuel L. Pfaff; Ren-Ping Zhou; Judy C. Young; Hayflick; Peter H. Duesberg

October 1, 1985

Synthetic peptide approach to the analysis of kinase activities of avian EGF receptor and v-erbB protein

Biochimie, ISSN: 61831638 03009084

Richard Kris; Lax; Sasson; Copf; Werlin; Gullick; Waterfield; Axel Ullrich; Fridkin; Schlessinger

September 11, 1985

Human lymphotoxin and tumor necrosis factor genes: Structure, homology and chromosomal localization

Nucleic Acids Research, ISSN: 03051048

Nedwin; Susan L. Naylor; Alan Y. Sakaguchi; Smith; Jarrett-Nedwin; Diane Pennica; David V. Goeddel; Patrick W. Gray

September 1, 1985

2-[(4-Azido-2-nitrophenyl)amino]ethyl Triphosphate, a Novel Chromophoric and Photoaffinity Analogue of ATP. Synthesis, Characterization, and Interaction with Myosin Subfragment 1

Biochemistry, ISSN: 15204995 00062960

Kay L. Nakamaye; Ralph G. Yount; James A. Wells; Robert L. Bridenbaugh; Yoh Okamoto

August 7, 1985

Nucleotide sequence of two overlapping myc-related genes in avian carcinoma virus OK10 and their relation to the myc genes of other viruses and the cell

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Hayflick; Peter H. Seeburg; Ohlsson; Pfeifer-Ohlsson; Watson; Papas; Peter H. Duesberg

August 7, 1985

Sequence variation in the gene for the immunogenic capsid protein VP1 of foot-and-mouth disease virus type A

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Weddell; Yansura; Dowbenko; Hoatlin; Grubman; Moore; Dennis G. Kleid

June 19, 1985

Human tumor necrosis factor: Production, purification, and characterization

Journal of Biological Chemistry, ISSN: 00219258

Aggarwal; William J. Kohr; Hass; Moffat; Steven A. Spencer; William J. Henzel; Timothy S. Bringman; Nedwin; David V. Goeddel; Harkins

June 19, 1985

Primary structure of human lymphotoxin derived from 1788 lymphoblastoid cell line

Journal of Biological Chemistry, ISSN: 00219258

Aggarwal; William J. Henzel; Moffat; William J. Kohr; Harkins

June 1, 1985

Sedimentation Equilibrium Measurements of the Intermediate-Size Tobacco Mosaic Virus Protein Polymers

Biochemistry, ISSN: 15204995 00062960

John J. Correia; Steven J. Shire; David A. Yphantis; Todd M. Schuster

May 11, 1985

ANTENATAL DIAGNOSIS AND CARRIER DETECTION OF HAEMOPHILIA A USING FACTOR VIII GENE PROBE

The Lancet, ISSN: 01406736

Jane Gitschier; Lawn; Frances Rotblat; Goldman; Tuddenham

May 8, 1985

Interferon-γ enhances induction of lymphotoxin in recombinant interleukin 2-stimulated peripheral blood mononuclear cells

Journal of Immunology, ISSN: 00221767

Svedersky; Nedwin; David V. Goeddel; Michael A. Palladino

January 1, 1985

Isolation of an alanine racemase gene from bacillus subtilis and its use for plasmid maintenance in B. Subtilis

Bio/Technology, ISSN: 0733222X

Ferrari; Henner; Yang

January 1, 1985

[33] Human lymphotoxin

Methods in Enzymology, ISSN: 15577988 00766879

Aggarwal

January 1, 1985

[34] Human tumor necrosis factor

Methods in Enzymology, ISSN: 15577988 00766879

Aggarwal; William J. Kohr

January 1, 1985

Purification and characterization of recombinant urokinase from escherichia COU

Bio/Technology, ISSN: 0733222X

Winkler; Michael Blaber; Bennett; William E. Holmes; Gordon A. Vehar

January 1, 1985

Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene

Science, ISSN: 00368075

Lisa Coussens; Yang-Feng; Yu-Cheng Liao; Ellson Y. Chen; Gray; McGrath; Peter H. Seeburg; Towia A. Libermann; Schlessinger; Uta Francke; Levinson; Axel Ullrich

January 1, 1985

In vivo augmentation of natural killer activity by combined treatment with recombinant gamma interferon and interleukin-2

Journal of Interferon Research, ISSN: 01978357

Shalaby; Svedersky; McKay; Bryan S Finkle; Michael A. Palladino

January 1, 1985

The neu gene: An erbB-homologous gene distinct from and unlinked to the gene encoding the EGF receptor

Science, ISSN: 00368075

Alan L. Schechter; Mien-Chie Hung; Lalitha Vaidyanathan; Robert A. Weinberg; Yang-Feng; Uta Francke; Axel Ullrich; Lisa Coussens

January 1, 1985

Bovine interferon-alphaI1 is an effective inhibitor of bovine herpes virus-1 induced respiratory disease

Antiviral Research, ISSN: 01663542

Christine W. Czarniecki; Anderson; Fennie; H. Bielefeldt Ohmann; Lorne A. Babiuk

January 1, 1985

Structure and chromosomal localization of the human lymphotoxin gene

Journal of Cellular Biochemistry, ISSN: 10974644 07302312

Nedwin; Jarrett-Nedwin; Smith; Susan L. Naylor; Alan Y. Sakaguchi; David V. Goeddel; Patrick W. Gray

January 1, 1985

Expression of normal and activated human Ha-ras cdnas in Saccharomyces cerevisiae

Molecular and Cellular Biology, ISSN: 02707306

Clark; McGrath; Levinson

January 1, 1985

Mammalian Expression of Cloned cDNA Sequences Encoding Human Purine Nucleoside Phosphorylase and Adenosine Deaminase

Annals of the New York Academy of Sciences, ISSN: 17496632 00778923

R.Scott McIvor; Valerio; Steven R. Williams; Goddard; Simonsen; Marja G.C. Duyvesteyn; Hans van Ormondt; Alex J. van der Eb; Martin Jr.

January 1, 1985

1-Methyl-2-(2-hydroxyphenyl)imidazole: A Catalytic Phosphate Protecting Group in Deoxyoligonucleotide Synthesis

Journal of the American Chemical Society, ISSN: 15205126 00027863

Froehler; Matteucci

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