Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 3351 - 3400 OF 15390 RESULTS

Quantitative X-Ray Microcomputed Tomography Assessment of Internal Tablet Defects
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Edward Yost; Pascal Chalus; Shawn Zhang; Stefanie Peter; Ajit S. Narang
View on Scopus
Durability of Diabetic Retinopathy Improvement with As-Needed Ranibizumab: Open-Label Extension of RIDE and RISE Studies
Ophthalmology, ISSN: 15494713 01616420
Jennifer K. Sun; Pin-Wen Wang; Sarah Taylor; Zdenka Haskova
View on Scopus
Quantitative neuroimaging measures of myelin in the healthy brain and in multiple sclerosis
Human Brain Mapping, ISSN: 10970193 10659471
Jonathan O'Muircheartaigh; Irene Vavasour; Emil Ljungberg; David K. B. Li; Alexander Rauscher; Victoria Levesque; Hideki Garren; David Clayton; Roger Tam; Traboulsee; Shannon Kolind
View on Scopus
Development of a Subcutaneous Fixed-Dose Combination of Pertuzumab and Trastuzumab: Results From the Phase Ib Dose-Finding Study
Journal of Clinical Pharmacology, ISSN: 15524604 00912700
Whitney P. Kirschbrown; Chris J. Wynne; Kagedal; Russell D. Wada; Hanbin Li; Wang; Ihsan Nijem; Tanja Badovinac-Crnjevic; Helena Gasser; Sarah Heeson; Jennifer Eng-Wong; Amit Garg
View on Scopus
Safety and efficacy of vismodegib in relapsed/refractory acute myeloid leukaemia: results of a phase Ib trial
British Journal of Haematology, ISSN: 13652141 00071048
Dale Bixby; Richard Noppeney; Tara L. Lin; Jorge E. Cortes; Jürgen Krauter; Karen Yee; Bruno C. Medeiros; Alwin Krämer; Sarit E. Assouline; Walter Fiedler; Natalie Dimier; Brian Simmons; Todd Riehl; Dawn Colburn
View on Scopus
Structure- and Ligand-Based Discovery of Chromane Arylsulfonamide Nav1.7 Inhibitors for the Treatment of Chronic Pain
Journal of Medicinal Chemistry, ISSN: 15204804 00222623
Steven J. McKerrall; Nguyen; Kwong Wah Lai; Philippe Bergeron; Lunbin Deng; Antonio G. DiPasquale; Jae H. Chang; Jun Chen; Tania Chernov-Rogan; David Hackos; Jonathan M. Maher; Daniel F. Ortwine; Jodie Pang; Jian Payandeh; William R. Proctor; Shannon D. Shields; Jennifer Vogt; Pengfei Ji; Wenfeng Liu; Elisa Ballini; Lilia Schumann; Glauco Tarozzo; Girish Bankar; Sultan Chowdhury; Abid Hasan; Johnson; Kuldip Khakh; Sophia Lin; Charles J. Cohen; Christoph Dehnhardt; Brian S. Safina; Daniel P. Sutherlin
View on Scopus
A prognostic model of persistent bacteremia and mortality in complicated staphylococcus aureus bloodstream infection
Clinical Infectious Diseases, ISSN: 15376591 10584838
Alessander O. Guimaraes; Yi Cao; Kyu Hong; Oleg Mayba; Melicent Peck; Johnny Gutierrez; Felicia Ruffin; Montserrat Carrasco-Triguero; Jason Dinoso; Angelo Clemenzi-Allen; Catherine A. Koss; Stacey A. Maskarinec; Chambers; Vance G. Fowler; Amos Baruch; Carrie M. Rosenberger
View on Scopus
Convergent Synthesis of PI3K Inhibitor GDC-0908 Featuring Palladium-Catalyzed Direct C-H Arylation toward Dihydrobenzothienooxepines
Journal of Organic Chemistry, ISSN: 15206904 00223263
Haiming Zhang; Beryl X. Li; Brian Wong; Andreas Stumpf; C. Gregory Sowell; Francis Gosselin
View on Scopus
Correction to: Long-term safety and efficacy of vismodegib in patients with advanced basal cell carcinoma: Final update of the pivotal ERIVANCE BCC study (BMC Cancer. (2017) 17 (332) DOI: 10.1186/s12885-017-3286-5)
BMC Cancer, ISSN: 14712407
Aleksandar Sekulic; Michael R. Migden; Nicole Basset-Seguin; Claus Garbe; Anja Gesierich; Christopher D. Lao; Chris Miller; Laurent Mortier; Dedee F. Murrell; Omid Hamid; Jorge F. Quevedo; Jeannie Hou; Edward McKenna; Natalie Dimier; Sarah Williams; Dirk Schadendorf; Axel Hauschild
View on Scopus
BcGST-an interactive bias-correction method to identify over-represented gene-sets in boutique arrays
Bioinformatics, ISSN: 14602059 13674803
Kevin Y.X. Wang; Alexander M. Menzies; Ines Pires da Silva; James S. Wilmott; Yibing Yan; Matthew Wongchenko; Richard F. Kefford; Richard A. Scolyer; Georgina V. Long; Garth Tarr; Samuel Mueller; Yang
View on Scopus
Central nervous system metastasis in patients with HER2-positive metastatic breast cancer: Patient characteristics, treatment, and survival from systhers
Clinical Cancer Research, ISSN: 15573265 10780432
Sara A. Hurvitz; O'Shaughnessy; Ginny Mason; Denise A. Yardley; Mohammad Jahanzeb; Adam Brufsky; Hope S. Rugo; Sandra M. Swain; Peter A. Kaufman; Debasish Tripathy; Laura Chu; Haocheng Li; Vincent Antao; Melody A. Cobleigh
View on Scopus
Human growth hormone
Pharmaceutical Biotechnology: Fundamentals and Applications,
Dao; Barbara M. Lippe; Mike Laird; Ingrid Beierle
View on Scopus
Recombinant human deoxyribonuclease I
Pharmaceutical Biotechnology: Fundamentals and Applications,
Lazarus; Wagener
View on Scopus
Monoclonal antibodies: From structure to therapeutic application
Pharmaceutical Biotechnology: Fundamentals and Applications,
Rong Deng; C. Andrew Boswell; Wendy Putnam; Meina Tao Tang; Amit Garg; Chunze Li; Shan Chung; Sandhya Girish
View on Scopus
General Purpose Water Model Can Improve Atomistic Simulations of Intrinsically Disordered Proteins
Journal of Chemical Theory and Computation, ISSN: 15499626 15499618
Parviz Seifpanahi Shabane; Saeed Izadi; Alexey V. Onufriev
View on Scopus
Autophagy Regulation of Metabolism Is Required for CD8 + T Cell Anti-tumor Immunity
Cell Reports, ISSN: 22111247
Devorkin; Nils Pavey; Gillian Carleton; Alexandra Comber; Cally Ho; Junghyun Lim; Erin McNamara; Haochu Huang; Kim; Lauren G. Zacharias; Noboru Mizushima; Tatsuya Saitoh; Shizuo Akira; Wayne Beckham; Alireza Lorzadeh; Michelle Moksa; Qi Cao; Aditya Murthy; Martin Hirst; DeBerardinis; Julian J. Lum
View on Scopus
RALying Regeneration through Wnt Internalization in Stem Cells
Cell Stem Cell, ISSN: 18759777 19345909
Helen Tauc; Heinrich Jasper
View on Scopus
Regulation of Tumor-Associated Myeloid Cell Activity by CBP/EP300 Bromodomain Modulation of H3K27 Acetylation
Cell Reports, ISSN: 22111247
Denise De Almeida Nagata; Eugene Y. Chiang; Suchit Jhunjhunwala; Patrick Caplazi; Vidhyalakshmi Arumugam; Zora Modrusan; Emily Chan; Mark Merchant; Lingyan Jin; David Arnott; F. Anthony Romero; Steven Magnuson; Karen Gascoigne; Jane L. Grogan
View on Scopus
Single-institution retrospective review of patients with recurrent glioblastoma treated with bevacizumab in clinical practice
Health Science Reports, ISSN: 23988835
Annick Desjardins; James E. Herndon; Frances McSherry; Arliene Ravelo; Eric S. Lipp; Patrick Healy; Katherine B. Peters; John H. Sampson; Dina Randazzo; Nicolas Sommer; Allan H. Friedman; Henry S. Friedman
View on Scopus
IMpower030: Phase III study evaluating neoadjuvant treatment of resectable stage II-IIIB non-small cell lung cancer (NSCLC) with atezolizumab (atezo) + chemotherapy
Annals of Oncology, ISSN: 15698041
Solange Peters; Kim; Benjamin Solomon; David R. Gandara; Rafal Dziadziuszko; Brunelli; Marina C. Garassino; Martin Reck; Wang; To; Sun; Barbara Gitlitz; Alan Sandler; Naiyer A. Rizvi
View on Scopus
Prognostic power of pathogen cell-free DNA in staphylococcus aureus bacteremia
Open Forum Infectious Diseases, ISSN: 23288957
Alessander O. Guimaraes; Johnny Gutierrez; Stacey A. Maskarinec; Yi Cao; Kyu Hong; Felicia Ruffin; Montserrat Carrasco-Triguero; Melicent Peck; Vance G. Fowler; Amos Baruch; Carrie M. Rosenberger
View on Scopus
Sustained circulating bacterial deoxyribonucleic acid is associated with complicated staphylococcus aureus bacteremia
Open Forum Infectious Diseases, ISSN: 23288957
Johnny Gutierrez; Alessander O. Guimaraes; Nicholas Lewin-Koh; Aklile Berhanu; Min Xu; Yi Cao; Janice Kim; Donghong Yan; Joanna K. Chang; Jason Dinoso; Catherine A. Koss; Angelo Clemenzi-Allen; Chambers; Melicent Peck; Amos Baruch; Carrie M. Rosenberger
View on Scopus
A rapid derivatization based LC-MS/MS method for quantitation of short chain fatty acids in human plasma and urine
Bioanalysis, ISSN: 17576199 17576180
Allan Jaochico; Dewakar Sangaraju; Sheerin Shahidi-Latham
View on Scopus
Incidence and risk of glucocorticoid-associated adverse effects in patients with rheumatoid arthritis
Arthritis Care and Research, ISSN: 21514658 2151464X
Jessica C. Wilson; Khaled Sarsour; Sara Gale; Attila Pethö-Schramm; Susan S. Jick; Christoph R. Meier
View on Scopus
Anti-PD-L1 treatment results in functional remodeling of the macrophage compartment
Cancer Research, ISSN: 15387445 00085472
Huizhong Xiong; Stephanie Mittman; Ryan Rodriguez; Marina Moskalenko; Patricia Pacheco-Sanchez; Yagai Yang; Dorothee Nickles; Rafael Cubas
View on Scopus
The Gag protein PEG10 binds to RNA and regulates trophoblast stem cell lineage specification
PLoS ONE, ISSN: 19326203
Mona Abed; Erik Verschueren; Hanna G. Budayeva; Peter S. Liu; Donald S. Kirkpatrick; Rohit Reja; Sarah K. Kummerfeld; Webster; Sarah Gierke; Mike Reichelt; Keith R. Anderson; Robert J. Newman; Merone Roose-Girma; Zora Modrusan; Hazal Pektas; Emin Maltepe; Kim Newton; Vishva M. Dixit
View on Scopus
Low-pass whole-genome sequencing of circulating cell-free DNA demonstrates dynamic changes in genomic copy number in a squamous lung cancer clinical cohort
Clinical Cancer Research, ISSN: 15573265 10780432
Xiaoji Chen; Ching-Wei Chang; Jill M. Spoerke; Kathryn E. Yoh; Vidushi Kapoor; Charles Baudo; Junko Aimi; Mamie Yu; May M. Y. Liang-Chu; Rebecca Suttmann; Huw; Steven Gendreau; Cummings; Lackner
View on Scopus
Activation of naïve CD4 + T cells re-tunes STAT1 signaling to deliver unique cytokine responses in memory CD4 + T cells
Nature Immunology, ISSN: 15292916 15292908
Jason P. Twohig; Ana Cardus Figueras; Robert Andrews; Florian Wiede; Benjamin C. Cossins; Alicia Derrac Soria; Myles J. Lewis; Michael J. Townsend; David Millrine; Jasmine Li; David G. Hill; Javier Uceda Fernandez; Xiao Liu; Barbara Szomolay; Christopher J. Pepper; Philip R. Taylor; Costantino Pitzalis; Tony Tiganis; Nigel Williams; Gareth W. Jones; Simon A. Jones
View on Scopus
Structurally-defined deubiquitinase inhibitors provide opportunities to investigate disease mechanisms
Drug Discovery Today: Technologies, ISSN: 17406749
Ingrid E. Wertz; Jeremy Murray
View on Scopus
A comparison of total and plasma membrane abundance of transporters in suspended, plated, sandwich-cultured human hepatocytes versus human liver tissue using quantitative targeted proteomics and cell surface biotinylation S
Drug Metabolism and Disposition, ISSN: 1521009X 00909556
Vineet Kumar; Laurent Salphati; Cornelis E. Hop; Guangqing Xiao; Yurong Lai; Anita Mathias; Xiaoyan Chu; W. Griffith Humphreys; Mingxiang Liao; Scott Heyward; Jashvant D. Unadkat
View on Scopus
Exposure–Response-Based Product Profile–Driven Clinical Utility Index for Ipatasertib Dose Selection in Prostate Cancer
CPT: Pharmacometrics and Systems Pharmacology, ISSN: 21638306
Rui Zhu; Bill Poland; Russell D. Wada; Qi Liu; Luna Musib; Daniel Maslyar; Eunpi Cho; Wei Yu; Han Ma; Jin Yan Jin; Nageshwar Budha
View on Scopus
Cost-Effectiveness Analysis of Pertuzumab With Trastuzumab and Chemotherapy Compared to Trastuzumab and Chemotherapy in the Adjuvant Treatment of HER2-Positive Breast Cancer in the United States
Value in Health, ISSN: 15244733 10983015
Louis P. Garrison Jr.; Joseph B. Babigumira; Clément Tournier; Hans-Peter Goertz; Solomon J. Lubinga; Edith A. Perez
View on Scopus
Efficacy of Pirfenidone in the Context of Multiple Disease Progression Events in Patients With Idiopathic Pulmonary Fibrosis
Chest, ISSN: 19313543 00123692
Steven D Nathan; Ulrich Costabel; Ian Glaspole; Marilyn K Glassberg; Lisa H Lancaster; David J. Lederer; Carlos A Pereira; Benjamin L. Trzaskoma; Elizabeth A. Morgenthien; Susan L. Limb; Athol Wells
View on Scopus
New tools for pathology: a user's review of a highly multiplexed method for in situ analysis of protein and RNA expression in tissue
Journal of Pathology, ISSN: 10969896 00223417
Jérémie Decalf; Matthew L. Albert; James Ziai
View on Scopus
c-Maf-dependent Treg cell control of intestinal TH17 cells and IgA establishes host–microbiota homeostasis
Nature Immunology, ISSN: 15292916 15292908
Christian Neumann; Jonas Blume; Urmi Roy; Peggy P. Teh; Ajithkumar Vasanthakumar; Alexander Beller; Yang Liao; Frederik Heinrich; Teresita L. Arenzana; Jason A. Hackney; Celine Eidenschenk; Eric J. C. Gálvez; Christina Stehle; Gitta A. Heinz; Patrick Maschmeyer; Tom Sidwell; Yifang Hu; Derk Amsen; Chiara Romagnani; Hyun-Dong Chang; Andrey Kruglov; Mir-Farzin Mashreghi; Wei Shi; Till Strowig; Sascha Rutz; Axel Kallies; Alexander Scheffold
View on Scopus
Determination of a novel antifibrotic small molecule GDC-3280 in human plasma and urine by liquid chromatography tandem mass spectrometry to support its first-in-human clinical trial
Biomedical chromatography : BMC, ISSN: 10990801 02693879
Jianshuang Wang; Michael Van Parys; Lin Pan; Yuan Chen; Dorothy S. Cheung; McKnight; Dennis Milanowski; Xiao Ding; Brian J. Dean
View on Scopus
Interaction of cell culture process parameters for modulating mAb afucosylation
Biotechnology and Bioengineering, ISSN: 10970290 00063592
Anh Nguyen Dang; Melissa Mun; Christopher M. Rose; Patrick Ahyow; Angela Meier; Wendy N. Sandoval; Inn H. Yuk
View on Scopus
Unexpected equivalent potency of a constrained chromene enantiomeric pair rationalized by co-crystal structures in complex with estrogen receptor alpha
Bioorganic and Medicinal Chemistry Letters, ISSN: 14643405 0960894X
Birong Zhang; James R. Kiefer; Robert A. Blake; Jae H. Chang; Steven J. Hartman; Ellen Ingalla; Tracy L. Kleinheinz; Vidhi Mody; Michelle Nannini; Daniel F. Ortwine; Yingqing Ran; Amy Sambrone; Deepak Sampath; Maia Vinogradova; Yu Zhong; Jerome C. Nwachukwu; Kendall W. Nettles; Tommy Lai; Jiangpeng Liao; Xiaoping Zheng; Hai Chen; Xiaojing Wang; Jun Liang
View on Scopus
Risk of serious infections in tocilizumab versus other biologic drugs in patients with rheumatoid arthritis: A multidatabase cohort study
Annals of the Rheumatic Diseases, ISSN: 14682060 00034967
Ajinkya Pawar; Rishi J. Desai; Daniel H. Solomon; Adrian J. Santiago Ortiz; Sara Gale; Bao; Khaled Sarsour; Sebastian Schneeweiss; Seoyoung C. Kim
View on Scopus
Characterizing and enhancing virus removal by protein A chromatography
Biotechnology and Bioengineering, ISSN: 10970290 00063592
Chinwei Pan; Alejandro Becerra-Arteaga; Benjamin Tran; Michael Chinn; Hua Wang; Qi Chen; Herbert Lutz; Min Zhang
View on Scopus
Omalizumab effectiveness in asthma-COPD overlap: Post hoc analysis of PROSPERO
Journal of Allergy and Clinical Immunology, ISSN: 10976825 00916749
Nicola A. Hanania; Bradley E. Chipps; Noelle M. Griffin; Bongin Yoo; Ahmar Iqbal; Thomas B. Casale
View on Scopus
Muscle specific kinase (MuSK) activation preserves neuromuscular junctions in the diaphragm but is not sufficient to provide a functional benefit in the SOD1G93A mouse model of ALS
Neurobiology of Disease, ISSN: 1095953X 09699961
Arundhati Sengupta Ghosh; Sara L. Dominguez; Luke Xie; Kai H. Barck; Zhiyu Jiang; Timothy K. Earr; Jose Imperio; Lilian Phu; Hanna G. Budayeva; Donald S. Kirkpatrick; Hao Cai; Jeffrey Eastham-Anderson; Hai Ngu; Oded Foreman; Maj Hedehus; Mike Reichelt; Isidro Hötzel; Yonglei Shang; Richard A. D. Carano; Gai Ayalon; Amy Easton
View on Scopus
Pyruvate Kinase Muscle-1 Expression Appears to Drive Lactogenic Behavior in CHO Cell Lines, Triggering Lower Viability and Productivity: A Case Study
Biotechnology Journal, ISSN: 18607314 18606768
Danming Tang; Jayashree Subramanian; Benjamin Haley; Jordan Baker; Lucas Luo; Wendy Hsu; Peter S. Liu; Wendy N. Sandoval; Mike Laird; Snedecor; Masaru Shiratori; Shahram Misaghi
View on Scopus
CLINICOPATHOLOGIC CORRELATION OF GEOGRAPHIC ATROPHY SECONDARY TO AGE-RELATED MACULAR DEGENERATION
Retina, ISSN: 15392864 0275004X
Miaoling Li; Rosa Dolz-Marco; Carrie Huisingh; Jeffrey D. Messinger; Richard M. Feist; Daniela Ferrara; K. Bailey Freund; Christine A. Curcio; David J. Wilson
View on Scopus
Bevacizumab at first recurrence after standard radio-chemotherapy is associated with improved overall survival in glioblastoma patients with large tumor burden
Neuro-Oncology Practice, ISSN: 20542585 20542577
Huy Tram Nguyen; Nhung Nguyen; Liang Yen Liu; Laura Dovek; Daniel Lenchner; Robert J. Harris; Byram Ozer; Arliene Ravelo; Nicolas Sommer; Myung Shin Sim; Robert Elashoff; Richard Green; Phioanh L. Nghiemphu; Timothy Cloughesy; Benjamin M. Ellingson; Albert Lai
View on Scopus
Introduction of a process mass intensity metric for biologics
New Biotechnology, ISSN: 18764347 18716784
Kristi L. Budzinski; Megan Blewis; Philip Dahlin; Daniel D'Aquila; Julia Esparza; Jack Gavin; Sa V. Ho; Clarice Hutchens; David Kahn; Stefan G. Koenig; Robert E. Kottmeier; Jeff Millard; Matt Snyder; Stanard; Lixin Sun
View on Scopus
Structural basis of a-scorpion toxin action on Na v channels
Science, ISSN: 10959203 00368075
Thomas Clairfeuille; Alexander Cloake; Daniel T. Infield; José P. Llongueras; Christopher P. Arthur; Zhong Rong Li; Yuwen Jian; Marie-France Martin-Eauclaire; Pierre E. Bougis; Claudio Ciferri; Christopher A. Ahern; Frank Bosmans; David Hackos; Alexis Rohou; Jian Payandeh
View on Scopus
Obinutuzumab plus CHOP is effective and has a tolerable safety profile in previously untreated, advanced diffuse large B-cell lymphoma: the phase II GATHER study
Leukemia and Lymphoma, ISSN: 10292403 10428194
Jeff P. Sharman; Andres Forero; Luciano J. Costa; Ian W. Flinn; Lowell Inhorn; Kevin Kelly; Alberto Bessudo; Luis E. Fayad; Kaminski; Andrew M. Evens; Christopher R. Flowers; Deniz Sahin; Kirsten E. Mundt; Thomas Sandmann; Guenter Fingerle-Rowson; Charlotte Vignal; Mehrdad Mobasher; Zelenetz
View on Scopus
Application and practice of digital pathology
Pathological Specimens And Genomic Medicine: Emerging Issues,
Webster; Jeffrey Eastham-Anderson
View on Scopus
Genomic and Transcriptomic Landscape of Triple-Negative Breast Cancers: Subtypes and Treatment Strategies
Cancer Cell, ISSN: 18783686 15356108
Yi-Zhou Jiang; Ding Ma; Chen Suo; Jinxiu Shi; Mengzhu Xue; Xin Hu; Yi Xiao; Ke-Da Yu; Yi-Rong Liu; Ying Yu; Yuanting Zheng; Xiangnan Li; Chenhui Zhang; Pengchen Hu; Jing Zhang; Qi Hua; Jiyang Zhang; Wanwan Hou; Luyao Ren; Ding Bao; Bingying Li; Jingcheng Yang; Ling Yao; Wen-Jia Zuo; Shen Zhao; Yue Gong; Yi-Xing Ren; Ya-Xin Zhao; Yun-Song Yang; Zhenmin Niu; Zhi-Gang Cao; Daniel G. Stover; Claire F. Verschraegen; Virginia Kaklamani; Anneleen Daemen; John R. Benson; Kazuaki Takabe; Fan Bai; Da-Qiang Li; Peng Wang; Leming Shi; Wei Huang; Zhimin Shao
View on Scopus
© 2024 Genentech, Inc. All rights reserved. This site is intended for US residents only.