Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 3601 - 3650 OF 15390 RESULTS

Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies
Neuron, ISSN: 10974199 08966273
Borislav Dejanovic; Melanie A. Huntley; Ann De Mazière; William J. Meilandt; Tiffany Wu; Karpagam Srinivasan; Zhiyu Jiang; Vineela D. Gandham; Brad A. Friedman; Hai Ngu; Oded Foreman; Richard A. D. Carano; Ben Chih; Judith Klumperman; Corey Bakalarski; Jesse E. Hanson; Morgan Sheng
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The Dendritic Cell Strikes Back
Immunity, ISSN: 10974180 10747613
Christine Moussion; Ira Mellman
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Serum periostin levels in adults of Chinese descent: An observational study ACTRN12614000122651 ACTRN 11 Medical and Health Sciences 1102 Cardiorespiratory Medicine and Haematology
Allergy, Asthma and Clinical Immunology, ISSN: 17101492 17101484
Evan Tan; Rachel Varughese; Ruth Semprini; Barney Montgomery; Cecile Holweg; Julie Olsson; Caswell-Smith; James Fingleton; Mark Weatherall; Beasley; Irene Braithwaite
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ORAI1, STIM1/2, and RYR1 shape subsecond Ca 2+ microdomains upon T cell activation
Science Signaling, ISSN: 19379145 19450877
Björn-Philipp Diercks; René Werner; Paula Weidemüller; Frederik Czarniak; Lola Hernandez; Cari Lehmann; Annette Rosche; Aileen Krüger; Ulrike Kaufmann; Martin Vaeth; Antonio V. Failla; Bernd Zobiak; Farid I. Kandil; Daniel Schetelig; Alexandra Ruthenbeck; Chris Meier; Dmitri Lodygin; Alexander Flügel; Dejian Ren; Insa M.A. Wolf; Stefan Feske; Andreas H. Guse
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IFNg-induced Chemokines Are Required for CXCR3-mediated T-Cell Recruitment and Antitumor Efficacy of Anti-HER2/CD3 Bispecific Antibody
Clinical Cancer Research, ISSN: 15573265 10780432
Ji Li; Ryan Ybarra; Judy Mak; Aurelie Herault; Patricia De Almeida; Alfonso Arrazate; James Ziai; Klara Totpal; Melissa Junttila; Kevin B. Walsh; Teemu T. Junttila
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Current status and future opportunities in lung precision medicine research with a focus on biomarkers: An American Thoracic Society/National Heart, Lung, and Blood Institute Research Statement
American Journal of Respiratory and Critical Care Medicine, ISSN: 15354970 1073449X
Ann Chen Wu; James P. Kiley; Patricia J. Noel; Shashi Amur; Esteban G. Burchard; John P. Clancy; Joshua Galanter; Maki Inada; Tiffanie K. Jones; Jonathan A Kropski; James E. Loyd; Lawrence M. Nogee; Benjamin A. Raby; Angela J. Rogers; David A. Schwartz; Don D. Sin; Avrum Spira; Weiss; Lisa R. Young; Blanca E Himes
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Germline genetic polymorphisms influence tumor gene expression and immune cell infiltration
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 10916490 00278424
Yoong Wearn Lim; Haiyin Chen-Harris; Oleg Mayba; Steve Lianoglou; Arthur Wuster; Tushar Bhangale; Zia Khan; Sanjeev Mariathasan; Anneleen Daemen; Jens Reeder; Peter M. Haverty; William F. Forrest; Matthew J. Brauer; Ira Mellman; Matthew L. Albert
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CD226 regulates natural killer cell antitumor responses via phosphorylation-mediated inactivation of transcription factor FOXO1
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 10916490 00278424
Xiangnan Du; Patricia De Almeida; Nicholas A. Manieri; Denise De Almeida Nagata; Thomas D Wu; Kristin Harden Bowles; Vidhyalakshmi Arumugam; Jill Schartner; Rafael Cubas; Stephanie Mittman; Vincent Javinal; Keith R. Anderson; Søren Warming; Jane L. Grogan; Eugene Y. Chiang
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First-line atezolizumab plus chemotherapy in extensive-stage small-cell lung cancer
New England Journal of Medicine, ISSN: 15334406 00284793
Leora Horn; Mansfield; Szczȩsna; Havel; Maciej J Krzakowski; Hochmair; Huemer; György Losonczy; Melissa L. Johnson; Makoto Nishio; Martin Reck; Tony Mok; Lam; David S. Shames; Juan Liu; Beiying Ding; Ariel Lopez-Chavez; Fairooz F. Kabbinavar; Wei Lin; Alan Sandler; Stephen V. Liu
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More is not always better: hyperglutamylation leads to neurodegeneration
EMBO Journal, ISSN: 14602075 02614189
Anna Akhmanova; Casper C Hoogenraad
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Hippo pathway inhibition by blocking the YAP/TAZ–TEAD interface: a patent review
Expert Opinion on Therapeutic Patents, ISSN: 17447674 13543776
James J. Crawford; Sarah M. Bronner; Jason R. Zbieg
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A Tet-Off gene expression system for validation of antifungal drug targets in a murine invasive pulmonary aspergillosis model
Scientific Reports, ISSN: 20452322
Yutian Peng; Hua Zhang; Min Xu; Man-Wah Tan
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ASC- A nd caspase-8-dependent apoptotic pathway diverges from the NLRC4 inflammasome in macrophages
Scientific Reports, ISSN: 20452322
Bettina L. Lee; Kathleen M. Mirrashidi; Irma B. Stowe; Sarah K. Kummerfeld; Colin K. Watanabe; Benjamin Haley; Trinna L. Cuellar; Mike Reichelt; Nobuhiko Kayagaki
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Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes
Nature Communications, ISSN: 20411723
David S. Hewings; Johanna Heideker; Taylur P. Ma; Andrew P. AhYoung; Farid El Oualid; Alessia Amore; Gregory T. Costakes; Daniel Kirchhofer; Bradley Brasher; Thomas H. Pillow; Nataliya Popovych; Till Maurer; Carsten Schwerdtfeger; William F. Forrest; Kebing Yu; Flygare; Matthew Bogyo; Ingrid E. Wertz
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Antibody-mediated stabilization of NRG1 induces behavioral and electrophysiological alterations in adult mice
Scientific Reports, ISSN: 20452322
Sara L. Dominguez; Ganapati V. Hegde; Jesse E. Hanson; Hong Xiang; Danielle Mandikian; C. Andrew Boswell; Cecilia Chiu; Yan Wu; Siao Ping Tsai; Daniel Fleck; Martin Weber; Hai Ngu; Kimberly Scearce-Levie; Erica L. Jackson
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A targeted boost-and-sort immunization strategy using Escherichia coli BamA identifies rare growth inhibitory antibodies
Scientific Reports, ISSN: 20452322
Rajesh Vij; Zhonghua Lin; Nancy Y. Chiang; Jean-Michel Vernes; Kelly M. Storek; Summer Park; Joyce Chan; Y. Gloria Meng; Laetitia Comps-Agrar; Patricia Luhn; Sophia Lee; Kellen Schneider; Jack Bevers; Inna Zilberleyb; Christine Tam; Christopher M. Koth; Min Xu; Avinash Gill; Marcy Auerbach; Peter A. Smith; Steven T. Rutherford; Nakamura; Dhaya Seshasayee; Jian Payandeh; James T. Koerber
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Classical and alternative complement activation on photoreceptor outer segments drives monocyte-dependent retinal atrophy
Scientific Reports, ISSN: 20452322
Kenneth J. Katschke Jr.; Hongkang Xi; Christian Cox; Tom Truong; Yann Malato; Wyne P. Lee; Brent Mckenzie; Rommel Arceo; Jianhua Tao; Linda Rangell; Mike Reichelt; Laurie Diehl; Justin Elstrott; Robby M. Weimer; Menno Van Lookeren Campagne
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Testosterone is an endogenous regulator of BAFF and splenic B cell number
Nature Communications, ISSN: 20411723
Anna S. Wilhelmson; Marta Lantero Rodriguez; Alexandra Stubelius; Per Fogelstrand; Inger Johansson; Matthew B. Buechler; Steve Lianoglou; Varun N. Kapoor; Maria E. Johansson; Johan B. Fagman; Amanda Duhlin; Prabhanshu Tripathi; Alessandro Camponeschi; Bo T. Porse; Antonius G. Rolink; Hans Nissbrandt; Shannon J. Turley; Hans Carlsten; Inga-Lill Mårtensson; Mikael C. I. Karlsson; Åsa Tivesten
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Comprehensive analysis of single molecule sequencing-derived complete genome and whole transcriptome of Hyposidra talaca nuclear polyhedrosis virus
Scientific Reports, ISSN: 20452322
Thong T Nguyen; Kushal Suryamohan; Boney Kuriakose; Vasantharajan Janakiraman; Mike Reichelt; Subhra Chaudhuri; Joseph Guillory; Neethu Divakaran; Rabins; Ridhi Goel; Bhabesh Deka; Suman Sarkar; Preety Ekka; Yu-Chih Tsai; Derek Vargas; Sam Santhosh; Sangeetha Mohan; Chen-Shan Chin; Jonas Korlach; George Thomas; Azariah Babu; Somasekar Seshagiri
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No difference in cardiovascular risk of tocilizumab versus abatacept for rheumatoid arthritis: A multi-database cohort study
Seminars in Arthritis and Rheumatism, ISSN: 1532866X 00490172
Seoyoung C. Kim; Daniel H. Solomon; James R. Rogers; Sara Gale; Micki Klearman; Khaled Sarsour; Sebastian Schneeweiss
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Next generation sequencing identifies novel diseaseassociated BEST1 mutations in Bestrophinopathy patients
Scientific Reports, ISSN: 20452322
Thong T Nguyen; Poornachandra; Anshuman Verma; Ruchir A. Mehta; Sameer Phalke; Rajani Battu; Vedam Laxmi Ramprasad; Andrew S. Peterson; Arkasubhra Ghosh; Somasekar Seshagiri
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Manic Fringe deficiency imposes Jagged1 addiction to intestinal tumor cells
Nature Communications, ISSN: 20411723
Erika López-Arribillaga; Verónica Rodilla; Carlota Colomer; Anna Vert; Amy Shelton; Jason H. Cheng; Bing Yan; Abel Gonzalez-Perez; Melissa Junttila; Mar Iglesias; Ferran Torres; Joan Albanell; Alberto Villanueva; Anna Bigas; Christian W. Siebel; Lluis Espinosa
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Erratum to: Classical and alternative complement activation on photoreceptor outer segments drives monocyte-dependent retinal atrophy (Scientific Reports, (2018), 8, 1, (7348), 10.1038/s41598-018-25557-8)
Scientific Reports, ISSN: 20452322
Kenneth J. Katschke Jr.; Hongkang Xi; Christian Cox; Tom Truong; Yann Malato; Wyne P. Lee; Brent Mckenzie; Rommel Arceo; Jianhua Tao; Linda Rangell; Mike Reichelt; Laurie Diehl; Justin Elstrott; Robby M. Weimer; Menno Van Lookeren Campagne
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Erratum to: Comprehensive analysis of single molecule sequencing-derived complete genome and whole transcriptome of Hyposidra talaca nuclear polyhedrosis virus (Scientific Reports, (2018), 8, 1, (8924), 10.1038/s41598-018-27084-y)
Scientific Reports, ISSN: 20452322
Thong T Nguyen; Kushal Suryamohan; Boney Kuriakose; Vasantharajan Janakiraman; Mike Reichelt; Subhra Chaudhuri; Joseph Guillory; Neethu Divakaran; Rabins; Ridhi Goel; Bhabesh Deka; Suman Sarkar; Preety Ekka; Yu-Chih Tsai; Derek Vargas; Sam Santhosh; Sangeetha Mohan; Chen-Shan Chin; Jonas Korlach; George Thomas; Azariah Babu; Somasekar Seshagiri
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Prophylactic and therapeutic inhibition of allergic airway inflammation by probiotic Escherichia coli O83
Journal of Allergy and Clinical Immunology, ISSN: 10976825 00916749
Christian Zwicker; Priya Sarate; Mirjana Drinić; Katharina Ambroz; Elke Korb; Ursula Smole; Cordula Köhler; Mark S. Wilson; Hana Kozakova; Peter Sebo; Miloslav Kverka; Ursula Wiedermann; Irma Schabussova
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Higher ambient synaptic glutamate at inhibitory versus excitatory neurons differentially impacts NMDA receptor activity
Nature Communications, ISSN: 20411723
Lulu Yao; Teddy Grand; Jesse E. Hanson; Pierre Paoletti; Qiang Zhou
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Erratum to: Clinical activity and molecular correlates of response to atezolizumab alone or in combination with bevacizumab versus sunitinib in renal cell carcinoma (Nature Medicine, (2018), 24, 6, (749-757), 10.1038/s41591-018-0053-3)
Nature Medicine, ISSN: 1546170X 10788956
David McDermott; Mahrukh Huseni; Michael B. Atkins; Robert J. Motzer; Brian I. Rini; Bernard Escudier; Lawrence Fong; Richard W. Joseph; Sumanta Kumar Pal; James A. Reeves; Mario Sznol; John Hainsworth; W. Kimryn Rathmell; Walter M. Stadler; Thomas E. Hutson; Martin E. Gore; Alain Ravaud; Sergio Bracarda; Cristina Suárez; Riccardo Danielli; Viktor Gruenwald; Toni K. Choueiri; Dorothee Nickles; Suchit Jhunjhunwala; Elisabeth Piault-Louis; Alpa Thobhani; Jiaheng Qiu; Daniel S. Chen; Priti Hegde; Christina Schiff; Gregg D. Fine; Thomas Powles
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Application of a Novel ‘Make and Test in Parallel’ Strategy to Investigate the Effect of Formulation on the Pharmacokinetics of GDC-0810 in Healthy Subjects
Pharmaceutical Research, ISSN: 1573904X 07248741
Sravanthi Cheeti; Hao Helen Hou; Eric Nelson; Helen Walker; Buyun Chen; Roland Morley; Mary Gates; Luna Musib; Sandhya Girish; Srikumar Sahasranaman; Lichuan Liu
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Atezolizumab Treatment Beyond Progression in Advanced NSCLC: Results From the Randomized, Phase III OAK Study
Journal of Thoracic Oncology, ISSN: 15561380 15560864
David R. Gandara; Joachim Von Pawel; Julien Mazieres; Richard Sullivan; Åslaug Helland; Ji-Youn Han; Santiago Ponce Aix; Achim Rittmeyer; Fabrice Barlesi; Toshio Kubo; Keunchil Park; Jerome H Goldschmidt; Mayank Gandhi; Cindy Yun; Wei Yu; Christina Matheny; Pei He; Alan Sandler; Ballinger; Louis Fehrenbacher
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Clinical utility of a blood-based EGFR mutation test in patients receiving first-line erlotinib therapy in the ENSURE, FASTACT-2, and ASPIRATION studies
Lung Cancer, ISSN: 18728332 01695002
Yi-Long Wu; Victor Lee; Chong-Kin Liam; Shun Lu; Keunchil Park; Vichien Srimuninnimit; Jie Wang; Caicun Zhou; Anita Appius; Peter Button; Gregory Hooper; John F. Palma; Katja Schulze; Sidney Scudder; David S. Shames; Anny-Yue Yin; Guili Zhang; Tony Mok
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Computer-Based Intensity Measurement Assists Pathologists in Scoring Phosphatase and Tensin Homolog Immunohistochemistry — Clinical Associations in NSCLC Patients of the European Thoracic Oncology Platform Lungscape Cohort
Journal of Thoracic Oncology, ISSN: 15561380 15560864
Undine Rulle; Zoi Tsourti; Ruben Casanova; Karl-Friedrich Deml; Eric K. Verbeken; Erik Thunnissen; Arne Warth; Richard Cheney; Aleksandra Sejda; Ernst Jan M. Speel; Line Bille Madsen; Daisuke Nonaka; Atilio Navarro; Irene Sansano; Antonio Marchetti; Stephen P. Finn; Kim Monkhorst; Keith M. Kerr; Martina Haberecker; Chengguang Wu; Panagiota Zygoura; Roswitha Kammler; Thomas R. Geiger; Steven Gendreau; Katja Schulze; Bart Vrugt; Peter Wild; Holger Moch; Weder; Ata Tuna Ciftlik; Urania Dafni; Solange Peters; Lukas Bubendorf; Rolf A Stahel; Alex Soltermann
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Correction to: Application of a Novel ‘Make and Test in Parallel’ Strategy to Investigate the Effect of Formulation on the Pharmacokinetics of GDC-0810 in Healthy Subjects (Pharmaceutical Research, (2018), 35, 12, (233), 10.1007/s11095-018-2516-0)
Pharmaceutical Research, ISSN: 1573904X 07248741
Sravanthi Cheeti; Hao Helen Hou; Eric Nelson; Helen Walker; Buyun Chen; Roland Morley; Mary Gates; Luna Musib; Sandhya Girish; Srikumar Sahasranaman; Lichuan Liu
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Development and Validation of a High-Quality Composite Real-World Mortality Endpoint
Health Services Research, ISSN: 14756773 00179124
Melissa D. Curtis; Sandra D. Griffith; Melisa Tucker; Michael D. Taylor; William B. Capra; Gillis Carrigan; Ben Holzman; Aracelis Z. Torres; Paul You; Brandon Arnieri; Amy P. Abernethy
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Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events: Methods for item selection in industry-sponsored oncology clinical trials
Clinical Trials, ISSN: 17407753 17407745
Peter C. Trask; Amylou Dueck; Elisabeth Piault; Alicyn Campbell
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Harnessing the Potential of Emerging Digital Health and Biological Sampling Technologies for Clinical Drug Development: Promise to Reality
Clinical Pharmacology and Therapeutics, ISSN: 15326535 00099236
Prajakti A. Kothare; Pravin R. Jadhav; Pankaj Gupta; Jane Croft Harrelson; Leslie Dickmann
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Calpain-mediated tau fragmentation is altered in Alzheimer’s disease progression
Scientific Reports, ISSN: 20452322
Hsu-Hsin Chen; Peter S. Liu; Paul Auger; Seung-Hye Lee; Oskar Adolfsson; Lorianne Rey-Bellet; Julien Lafrance-Vanasse; Brad A. Friedman; Maria Pihlgren; Andreas Muhs; Andrea Pfeifer; James A. Ernst; Gai Ayalon; Kristin R. Wildsmith; Thomas G. Beach; Marcel P Van Der Brug
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TBK1 and IKKε restrain cell death
Nature Cell Biology, ISSN: 14764679 14657392
Klaus D. Heger; Vishva M. Dixit
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Nonclinical safety assessment of a human interleukin-22FC IG fusion protein demonstrates in vitro to in vivo and cross-species translatability
Pharmacology Research and Perspectives, ISSN: 20521707
Donna W. Lee; Shelly Zhong; Rama Pai; Julie Rae; Siddharth Sukumaran; Stefanich; Jeff Lutman; Estelle Doudement; Xiaoting Wang; Brandon Harder; Annemarie N. Lekkerkerker; Ann E. Herman; Wenjun Ouyang; Dimitry Danilenko
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89Zr-atezolizumab imaging as a non-invasive approach to assess clinical response to PD-L1 blockade in cancer
Nature Medicine, ISSN: 1546170X 10788956
Frederike Bensch; Elly L. van der Veen; Marjolijn N. Lub-de Hooge; Annelies Jorritsma-Smit; Ronald Boellaard; Iris C. Kok; Sjoukje F. Oosting; Carolien P. Schröder; T. Jeroen N. Hiltermann; Anthonie J. van der Wekken; Harry J.M. Groen; Thomas C. Kwee; Sjoerd G. Elias; Jourik A. Gietema; Sandra Sanabria Bohorquez; De Crespigny; Simon P. Williams; Christoph Mancao; Adrienne H. Brouwers; Bernard M. Fine; Elisabeth G. E. de Vries
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FAP delineates heterogeneous and functionally divergent stromal cells in immune-excluded breast tumors
Cancer immunology research, ISSN: 23266074 23266066
Viviana Cremasco; Jillian L. Astarita; Angelo L. Grauel; Shilpa Keerthivasan; Kenzie MacIsaac; Matthew C. Woodruff; Michael Wu; Lotte Spel; Stephen Santoro; Zohreh Amoozgar; Tyler Laszewski; Sara Cruz Migoni; Konstantin Knoblich; Anne L. Fletcher; Martin LaFleur; Kai Wucherpfennig; Puré; Glenn Dranoff; Michael C. Carroll; Shannon J. Turley
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Ocrelizumab reduces progression of upper extremity impairment in patients with primary progressive multiple sclerosis: Findings from the phase III randomized ORATORIO trial
Multiple Sclerosis Journal, ISSN: 14770970 13524585
Edward J Fox; Clyde Markowitz; Angela Applebee; Montalban; Wolinsky; Belachew; Damian Fiore; Jinglan Pei; Bruno Musch; Giovannoni
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2018 White Paper on Recent Issues in Bioanalysis: Focus on flow cytometry, gene therapy, cut points and key clarifications on BAV (Part 3 - LBA/cell-based assays: Immunogenicity, biomarkers and PK assays)
Bioanalysis, ISSN: 17576199 17576180
Lauren Stevenson; Richards; Renuka Pillutla; Albert Torri; John Kamerud; Devangi Mehta; Steve Keller; Shobha Purushothama; Boris Gorovits; Virginia Litwin; Christopher C. Stebbins; Joseph Marini; Chris Beaver; Gizette Sperinde; Patricia Siguenza; Roland F Staack; Yongchang Qiu; Lakshmi Amaravadi; Shashi Amur; Catherine Aversa Fleener; Daniel Baltrukonis; Ian Catlett; Elana Cherry; Shan Chung; Isabelle Cludts; Lorella Di Donato; Saloumeh Kadkhodayan Fischer; Stephanie Fraser; Fabio Garofolo; Cherie Green; George R. Gunn; Sam Haidar; Jonathan Haulenbeek; Neil Henderson; Shirley Hopper; Akiko Ishii-Watabe; Rafiqul Islam; Brian Janelsins; Vibha Jawa; Vellalore Kakkanaiah; Szilard Kamondi; Gerry Kolaitis; Robert J Kubiak; Seema Kumar; Pekka Kurki; Meina Liang; Patrick Liu; Kimberly Maxfield; Heather Myler; Nisha Palackal; Rachel Palmer; Joao Pedras-Vasconcelos; Steven Piccoli; Paul Rhyne; Yoshiro Saito; Natasha Savoie; Eginhard Schick; Becky Schweighardt; Judy Shih; An Song; Priya Sriraman; Ludovicus Staelens; Giane Sumner; Yongliang Sun; Martin Ullmann; Verthelyi; Meenu Wadhwa; Yow-Ming C. Wang; Yuanxin Xu; Haoheng Yan; Tong-Yuan Yang; Rong Zeng
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Identification and characterization of an octameric PEG-protein conjugate system for intravitreal long-acting delivery to the back of the eye
PLoS ONE, ISSN: 19326203
Whitney Shatz; Hass; Nikhil Peer; Maciej Paluch; Craig D. Blanchette; Guanghui Han; Wendy N. Sandoval; Ashley Morando; Kelly M. Loyet; Vlad Bantseev; Helen Booler; Susan R. Crowell; Amrita Kamath; Justin M. Scheer; Robert F. Kelley
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Transcriptomic analysis of hepatocellular carcinoma reveals molecular features of disease progression and tumor immune biology
npj Precision Oncology, ISSN: 2397768X
Kwame Okrah; Somayeh S. Tarighat; Bonnie Liu; Koeppen; Marie-Claire Wagle; Cheng; Sun; Anwesha Dey; Chang; Teiko Sumiyoshi; Zineb Mounir; Cummings; Garret M. Hampton; Lukas Amler; Jane Fridlyand; Priti Hegde; Shannon J. Turley; Lackner; Shih-Min A. Huang
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Risk Associated with Cumulative Oral Glucocorticoid Use in Patients with Giant Cell Arteritis in Real-World Databases from the USA and UK
Rheumatology and Therapy, ISSN: 21986584 21986576
Sara Gale; Jessica C. Wilson; Jenny Chia; Huong Trinh; Katie Tuckwell; Neil Collinson; Sophie Dimonaco; Susan S. Jick; Christoph R. Meier; Shalini V. Mohan; Khaled Sarsour
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A transcriptional MAPK Pathway Activity Score (MPAS) is a clinically relevant biomarker in multiple cancer types
npj Precision Oncology, ISSN: 2397768X
Marie-Claire Wagle; Kirouac; Christiaan N. Klijn; Bonnie Liu; Shilpi Mahajan; Melissa Junttila; John Moffat; Mark Merchant; Huw; Matthew Wongchenko; Kwame Okrah; Shrividhya Srinivasan; Zineb Mounir; Teiko Sumiyoshi; Peter M. Haverty; Robert Yauch; Yibing Yan; Omar Kabbarah; Garret M. Hampton; Lukas Amler; Ramanujan; Lackner; Shih-Min A. Huang
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Transcriptomic analysis of hepatocellular carcinoma reveals molecular features of disease progression and tumor immune biology
npj Precision Oncology, ISSN: 2397768X
Kwame Okrah; Somayeh S. Tarighat; Bonnie Liu; Koeppen; Marie-Claire Wagle; Cheng; Sun; Anwesha Dey; Chang; Sumiyoshi; Zineb Mounir; Cummings; Garret M. Hampton; Lukas Amler; Jane Fridlyand; Priti Hegde; Shannon J. Turley; Lackner; Shih-Min A. Huang
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Transcriptomic analysis of hepatocellular carcinoma reveals molecular features of disease progression and tumor immune biology
npj Precision Oncology, ISSN: 2397768X
Kwame Okrah; Somayeh S. Tarighat; Bonnie Liu; Koeppen; Marie-Claire Wagle; Cheng; Sun; Anwesha Dey; Matthew T. Chang; Teiko Sumiyoshi; Zineb Mounir; Cummings; Garret M. Hampton; Lukas Amler; Jane Fridlyand; Priti Hegde; Shannon J. Turley; Lackner; Shih-Min A. Huang
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First inter-laboratory study of a Supercritical Fluid Chromatography method for the determination of pharmaceutical impurities
Journal of Pharmaceutical and Biomedical Analysis, ISSN: 1873264X 07317085
Amandine Dispas; Roland Marini; Vincent Desfontaine; Jean-Luc Veuthey; Dorina Kotoni; Luca Gioacchino Losacco; Adrian Clarke; Charlene Muscat Galea; Debby Mangelings; Brandon M. Jocher; Erik L. Regalado; Katerina Plachká; Lucie Nováková; Benjamin Wuyts; Isabelle François; Michael Gray; Andrew J. Aubin; Abhijit Tarafder; Maxime Cazes; Christophe Desvignes; Loic Villemet; Morgan Sarrut; Adrien Raimbault; Elise Lemasson; Eric Lesellier; Caroline West; Tomas Leek; Mengling Wong; Lulu Dai; Kelly Zhang; Alexandre Grand-Guillaume Perrenoud; Claudio Brunelli; Philippe Hennig; Sophie Bertin; Fabien Mauge; Nathalie Da Costa; William P. Farrell; Madeleine Hill; Niranjan Desphande; Manish Grangrade; Santosh Sadaphule; Ravi Yadav; Sandesh Rane; Shankar Shringare; Marion Iguiniz; Sabine Heinisch; Julien Lefevre; Estelle Corbel; Nicolas Roques; Yvan Vander Heyden; Davy Guillarme; Philippe Hubert
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Pathogen blockade of TAK1 triggers caspase-8–dependent cleavage of gasdermin D and cell death
Science, ISSN: 10959203 00368075
Pontus Orning; Dan Weng; Kristian Starheim; Dmitry Ratner; Zachary Best; Bettina L. Lee; Alexandria Brooks; Shiyu Xia; Hao Wu; Michelle A. Kelliher; Scott B. Berger; Peter J. Gough; John Bertin; Megan K. Proulx; Jon D. Goguen; Nobuhiko Kayagaki; Katherine A. Fitzgerald; Egil Lien
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