Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 4651 - 4700 OF 15390 RESULTS

From a novel HTS hit to potent, selective, and orally bioavailable KDM5 inhibitors
Bioorganic and Medicinal Chemistry Letters, ISSN: 14643405 0960894X
Jun Liang; Sharada Labadie; Birong Zhang; Daniel F. Ortwine; Snahel Patel; Maia Vinogradova; James R. Kiefer; Till Mauer; Victor S Gehling; Jean-Christophe Harmange; Richard T Cummings; Tommy Lai; Jiangpeng Liao; Xiaoping Zheng; Yichin Liu; Amy Gustafson; Erica Vanderporten; Weifeng Mao; Bianca M. Liederer; Gauri Deshmukh; Le An; Yingqing Ran; Marie Classon; Patrick Trojer; Peter Dragovich; Lesley J. Murray
View on Scopus
The second-generation maturation inhibitor GSK3532795 maintains potent activity toward HIV protease inhibitor-resistant clinical isolates
Journal of Acquired Immune Deficiency Syndromes, ISSN: 10779450 15254135
Neelanjana Ray; Tianbo Li; Zeyu Lin; Tricia Protack; Petronella Maria Van Ham; Carey Hwang; Mark Krystal; Monique Nijhuis; Max Lataillade; Ira Dicker
View on Scopus
Compartment based population balance model development of a high shear wet granulation process via dry and wet binder addition
Chemical Engineering Research and Design, ISSN: 02638762
Anik Chaturbedi; Chandra Kanth Bandi; Dheeraj Reddy; Preetanshu Pandey; Ajit S. Narang; Dilbir Bindra; Li Tao; Junshu Zhao; Jinjiang Li; Munir A. Hussain; Rohit Ramachandran
View on Scopus
Risk-based predictive stability-an industry perspective
Pharmaceutical Technology, ISSN: 21507376 15432521
Helen Williams; Dennis Stephens; Megan McMahon; Elke Debie; Fenghe Qiu; Cherokee Hoaglund-Hyzer; Lois Sechler; Rachel Orr; Debra Webb; Yan Wu; David Hahn
View on Scopus
Efficient mapping of transgene integration sites and local structural changes in Cre transgenic mice using targeted locus amplification
Nucleic Acids Research, ISSN: 13624962 03051048
Carol Cain-Hom; Erik Splinter; Max Van Min; Marieke Simonis; Monique Van De Heijning; Maria Martinez; Vida Asghari; J. Colin Cox; Søren Warming
View on Scopus
Inhibition of bromodomain-containing protein 9 for the prevention of epigenetically-defined drug resistance
Bioorganic and Medicinal Chemistry Letters, ISSN: 14643405 0960894X
Terry Crawford; Steffan Vartanian; Alexandre Côté; Steve Bellon; Martin Duplessis; E. Megan Flynn; Michael C. Hewitt; Hon-Ren Huang; James R. Kiefer; Jeremy Murray; Christopher G. Nasveschuk; Eneida Pardo; F. Anthony Romero; Peter Sandy; Yong Tang; Alexander M. Taylor; Vickie Tsui; Jian Wang; Shumei Wang; Laura E. Zawadzke; Brian K Albrecht; Steven Magnuson; Andrea G Cochran; David Stokoe
View on Scopus
FGF21-receptor agonists: An emerging therapeutic class for obesity-related diseases
Hormone Molecular Biology and Clinical Investigation, ISSN: 18681891 18681883
Junichiro Sonoda; Mark Chen; Amos Baruch
View on Scopus
Modeling renal cell carcinoma in mice: Bap1 and Pbrm1 inactivation drive tumor grade
Cancer Discovery, ISSN: 21598290 21598274
Yi-Feng Gu; Shannon Cohn; Alana Christie; Tiffani McKenzie; Nicholas Wolff; Quyen N. Do; Ananth J. Madhuranthakam; Ivan Pedrosa; Tao Wang; Anwesha Dey; Meinrad Busslinger; Xian-Jin Xie; Robert E. Hammer; Renée M. McKay; Payal Kapur; James Brugarolas
View on Scopus
High density lipoproteins and type 2 inflammatory biomarkers are negatively correlated in atopic asthmatics
Journal of Lipid Research, ISSN: 15397262 00222275
Amisha V. Barochia; Elizabeth M. Gordon; Maryann Kaler; Rosemarie A. Cuento; Patricia Theard; Debbie M. Figueroa; Xianglan Yao; Nargues A. Weir; Maureen L. Sampson; Mario Stylianou; David F. Choy; Cécile T.J. Holweg; Alan T. Remaley; Stewart J. Levine
View on Scopus
Current state of bow tie risk assessment method
Global Congress on Process Safety 2017 - Topical Conference at the 2017 AIChE Spring Meeting and 13th Global Congress on Process Safety,
Robin Pitblado; Tim McGrath; Mark Manton; Charles Ian Cowley; Kiran Krishna; Martin Johnson; Ron McLeod; Paul Haydock; Tatiana Norman
View on Scopus
A deeper shade of green: Inspiring sustainable drug manufacturing
Green Chemistry, ISSN: 14639270 14639262
Frank Roschangar; Juan Colberg; Peter Dunn; Fabrice Gallou; John Hayler; Stefan G. Koenig; Michael E. Kopach; David Leahy; Ingrid Mergelsberg; John L. Tucker; Roger A. Sheldon; Chris H. Senanayake
View on Scopus
Assessing Tumor-infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method from the International Immunooncology Biomarkers Working Group: Part 1: Assessing the Host Immune Response, TILs in Invasive Breast Carcinoma and Ductal Carcinoma in Situ, Metastatic Tumor Deposits and Areas for Further Research
Advances in Anatomic Pathology, ISSN: 15334031 10724109
Shona Hendry; Roberto Salgado; Thomas Gevaert; Prudence A. Russell; Tom John; Bibhusal Thapa; Michael Christie; Koen Van De Vijver; Mónica V. Estrada; Paula I. Gonzalez-Ericsson; Melinda E. Sanders; Benjamin Solomon; Cinzia Solinas; Gert G.G.M. Van Den Eynden; Yves Allory; Matthias Preusser; Johannes Hainfellner; Giancarlo Pruneri; Andrea Vingiani; Sandra Demaria; W Fraser Symmans; Nuciforo; Laura Comerma; Thompson; Sunil Lakhani; Seong-Rim Kim; Stuart J. Schnitt; Cecile Colpaert; Christos Sotiriou; Stefan J. Scherer; Michail Ignatiadis; Sunil Badve; Robert H. Pierce; Giuseppe Viale; Nicolas Sirtaine; Frederique Penault-Llorca; Tomohagu Sugie; Susan Fineberg; Soonmyung Paik; Ashok Srinivasan; Andrea Richardson; Yihong Wang; Ewa Chmielik; Jane Brock; Douglas B. Johnson; Justin M. Balko; Stephan Wienert; Veerle Bossuyt; Stefan Michiels; Nils Ternes; Nicole Burchardi; Stephen J Luen; Peter Savas; Frederick Klauschen; Peter H. Watson; Brad H. Nelson; Carmen Criscitiello; Sandra O'Toole; Denis Larsimont; Roland De Wind; Giuseppe Curigliano; Fabrice Andre; Magali Lacroix-Triki; Mark Van De Vijver; Federico Rojo; Giuseppe Floris; Shahinaz Bedri; Joseph Sparano; David Rimm; Torsten Nielsen; Zuzana Kos; Stephen M. Hewitt; Baljit Singh; Gelareh Farshid; Sibylle Loibl; Kimberly H. Allison; Nadine Tung; Sylvia Adams; Karen Willard-Gallo; Hugo M. Horlings; Leena Gandhi; Andre Moreira; Fred R. Hirsch; Maria V. Dieci; Maria Urbanowicz; Iva Brcic; Konstanty Korski; Fabien Gaire; Koeppen; Amy Lo; Jennifer M. Giltnane; Marlon C. Rebelatto; Keith E. Steele; Jiping Zha; Kenneth Emancipator; Jonathan W. Juco; Carsten Denkert; Jorge S. Reis-Filho; Sherene Loi; Stephen B. Fox
View on Scopus
Identification of an imidazopyridine scaffold to generate potent and selective TYK2 inhibitors that demonstrate activity in an in vivo psoriasis model
Bioorganic and Medicinal Chemistry Letters, ISSN: 14643405 0960894X
Jun Liang; Anne Van Abbema; Mercedesz Balazs; Kathy Barrett; Leo Berezhkovsky; Wade S. Blair; Christine Chang; Donnie Delarosa; Jason Devoss; James Driscoll; Eigenbrot; Simon Goodacre; Nico Ghilardi; Calum Macleod; Adam R. Johnson; Pawan Bir Kohli; Yingjie Lai; Zhonghua Lin; Priscilla Mantik; Kapil Menghrajani; Hieu Nguyen; Ivan Peng; Amy Sambrone; Steven Shia; Jan Smith; Sue J. Sohn; Vickie Tsui; Ultsch; Karen Williams; Lawren C. Wu; Wenqian Yang; Birong Zhang; Steven Magnuson
View on Scopus
Preferences for multiple sclerosis treatments: Using a discrete-choice experiment to examine differences across subgroups of US patients
International Journal of MS Care, ISSN: 15372073
Carol Mansfield; Nina Parikh Thomas; David Gebben; Maria Lucas; Brett Hauber
View on Scopus
Progranulin deficiency causes impairment of autophagy and TDP-43 accumulation
Journal of Experimental Medicine, ISSN: 15409538 00221007
Michael C. Chang; Karpagam Srinivasan; Brad A. Friedman; Eric Suto; Zora Modrusan; Wyne P. Lee; Joshua S. Kaminker; David V. Hansen; Morgan Sheng
View on Scopus
CYP1A1-mediated intramolecular rearrangement of aminoazepane in GDC-0339
Drug Metabolism and Disposition, ISSN: 1521009X 00909556
Ryan Takahashi; Xiaojing Wang; Nathaniel Segraves; Jing Wang; Jae H. Chang; S. Cyrus Khojasteh; Shuguang Ma
View on Scopus
Considerations from the IQ induction working group in response to drug-drug interaction guidance from regulatory agencies: Focus on downregulation, CYP2C induction, and CYP2B6 positive control
Drug Metabolism and Disposition, ISSN: 1521009X 00909556
Niresh Hariparsad; Diane Ramsden; Jairam Palamanda; Joshua G. DeKeyser; Odette A. Fahmi; Jane R. Kenny; Heidi J. Einolf; Michael A. Mohutsky; Magalie Pardon; Y. Amy Siu; Liangfu Chen; Michael Sinz; Barry C Jones; Robert L. Walsky; Shannon Dallas; Suresh K. Balani; George Zhang; David Buckley; Donald J. Tweedie
View on Scopus
Assessing Tumor-Infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method from the International Immuno-Oncology Biomarkers Working Group: Part 2: TILs in Melanoma, Gastrointestinal Tract Carcinomas, Non-Small Cell Lung Carcinoma and Mesothelioma, Endometrial and Ovarian Carcinomas, Squamous Cell Carcinoma of the Head and Neck, Genitourinary Carcinomas, and Primary Brain Tumors
Advances in Anatomic Pathology, ISSN: 15334031 10724109
Shona Hendry; Roberto Salgado; Thomas Gevaert; Prudence A. Russell; Tom John; Bibhusal Thapa; Michael Christie; Koen Van De Vijver; Mónica V. Estrada; Paula I. Gonzalez-Ericsson; Melinda E. Sanders; Benjamin Solomon; Cinzia Solinas; Gert G.G.M. Van Den Eynden; Yves Allory; Matthias Preusser; Johannes Hainfellner; Giancarlo Pruneri; Andrea Vingiani; Sandra Demaria; W Fraser Symmans; Nuciforo; Laura Comerma; Thompson; Sunil Lakhani; Seong-Rim Kim; Stuart J. Schnitt; Cecile Colpaert; Christos Sotiriou; Stefan J. Scherer; Michail Ignatiadis; Sunil Badve; Robert H. Pierce; Giuseppe Viale; Nicolas Sirtaine; Frederique Penault-Llorca; Tomohagu Sugie; Susan Fineberg; Soonmyung Paik; Ashok Srinivasan; Andrea Richardson; Yihong Wang; Ewa Chmielik; Jane Brock; Douglas B. Johnson; Justin M. Balko; Stephan Wienert; Veerle Bossuyt; Stefan Michiels; Nils Ternes; Nicole Burchardi; Stephen J Luen; Peter Savas; Frederick Klauschen; Peter H. Watson; Brad H. Nelson; Carmen Criscitiello; Sandra O'Toole; Denis Larsimont; Roland De Wind; Giuseppe Curigliano; Fabrice Andre; Magali Lacroix-Triki; Mark Van De Vijver; Federico Rojo; Giuseppe Floris; Shahinaz Bedri; Joseph Sparano; David Rimm; Torsten Nielsen; Zuzana Kos; Stephen M. Hewitt; Baljit Singh; Gelareh Farshid; Sibylle Loibl; Kimberly H. Allison; Nadine Tung; Sylvia Adams; Karen Willard-Gallo; Hugo M. Horlings; Leena Gandhi; Andre Moreira; Fred R. Hirsch; Maria V. Dieci; Maria Urbanowicz; Iva Brcic; Konstanty Korski; Fabien Gaire; Koeppen; Amy Lo; Jennifer M. Giltnane; Marlon C. Rebelatto; Keith E. Steele; Jiping Zha; Kenneth Emancipator; Jonathan W. Juco; Carsten Denkert; Jorge S. Reis-Filho; Sherene Loi; Stephen B. Fox
View on Scopus
Vemurafenib treatment for patients with locally advanced, unresectable stage IIIC or metastatic melanoma and activating exon 15 BRAF mutations other than V600E
Melanoma Research, ISSN: 14735636 09608931
Sigrun Hallmeyer; Rene Gonzalez; David Lawson; Lee Cranmer; Gerald Linette; Igor Puzanov; Bret Taback; C. Lance Cowey; Antoni Ribas; Gregory Daniels; Timothy Moore; Geoffrey T. Gibney; Hussein Tawbi; Eric Whitman; Geraldine Lee; Yong Mun; Shiyao Liu; Omid Hamid
View on Scopus
Enhancing the resolution of 1H and 13C solid-state NMR spectra by reduction of anisotropic bulk magnetic susceptibility broadening
Physical Chemistry Chemical Physics, ISSN: 14639076
Michael P. Hanrahan; Amrit Venkatesh; Scott L. Carnahan; Julie L. Calahan; Joseph W. Lubach; Eric Munson; Aaron J. Rossini
View on Scopus
Enhancing reproducibility and collaboration via management of R package cohorts
Journal of Statistical Software, ISSN: 15487660
Gabriel Becker; Robert Gentleman; Cory Barr; Michael Lawrence
View on Scopus
Cathepsin B is dispensable for cellular processing of cathepsin B-cleavable antibody–drug conjugates
Cancer Research, ISSN: 15387445 00085472
Niña G. Caculitan; Josefa Chuh; Yong Ma; Donglu Zhang; Katherine R. Kozak; Yichin Liu; Thomas H. Pillow; Jack D. Sadowsky; Tommy K. Cheung; Qui Phung; Benjamin Haley; Byoung-Chul Lee; Robert W. Akita; Mark X. Sliwkowski; Andrew G. Polson
View on Scopus
2017 White paper on recent issues in bioanalysis: Rise of hybrid lba/lcms immunogenicity assays (part 2: Hybrid lba/lcms biotherapeutics, biomarkers & immunogenicity assays and regulatory agencies' inputs)
Bioanalysis, ISSN: 17576199 17576180
Hendrik Neubert; An Song; Anita Lee; Cong Wei; Jeff Duggan; Keyang Xu; Eric Woolf; Christopher Evans; Joe Palandra; Omar Laterza; Shashi Amur; Isabella Berger; Mark Bustard; Mark T. Cancilla; Shang-Chiung Chen; Seongeun Julia Cho; Eugene Ciccimaro; Isabelle Cludts; Cocea; Celia D'Arienzo; Lieza Danan-Leon; Lorella Di Donato; Fabio Garofolo; Sam Haidar; Akiko Ishii-Watabe; Hao Jiang; John Kadavil; Sean Kassim; Pekka Kurki; Olivier Le Blaye; Kai Liu; Rod Mathews; Gustavo Mendes Lima Santos; Makoto Niwa; Joao Pedras-Vasconcelos; Mark Qian; Brian Rago; Ola M. Saad; Yoshiro Saito; Natasha Savoie; Dian Su; Matthew Szapacs; Nilufer Tampal; Stephen Vinter; Jian Wang; Jan Welink; Emma Whale; Amanda Wilson; Xue
View on Scopus
The comparative effectiveness and cost-effectiveness of ranibizumab for neovascular macular degeneration revisited
International Journal of Retina and Vitreous, ISSN: 20569920
Gary C. Brown; Melissa M. Brown; Heidi B. Lieske; Adam Turpcu; Yamina Rajput
View on Scopus
Practical considerations for assessing product ouality of biosynthetic proteins by HPLC
High-Performance Liquid Chromatography of Peptides and Proteins: Separation, Analysis, and Conformation,
Chloupek; John E. Battersby; William S. Hancock
View on Scopus
Results from the Phase III Randomized Trial of Onartuzumab plus Erlotinib Versus Erlotinib in Previously Treated Stage IIIB or IV Non–Small-Cell Lung Cancer: METLung
Journal of Clinical Oncology, ISSN: 15277755 0732183X
David Spigel; Martin J. Edelman; Kenneth O'Byrne; Luis Paz-Ares; Mocci; See Phan; David S. Shames; Dustin Smith; Wei Yu; Virginia Paton; Tony Mok
View on Scopus
Interleukin-13 in asthma and other eosinophilic disorders
Frontiers in Medicine, ISSN: 2296858X
Emma Doran; Fang Cai; Cecile Holweg; Kit Wong; Jochen Brumm; Joseph R. Arron
View on Scopus
Sembragiline in Moderate Alzheimer's Disease: Results of a Randomized, Double-Blind, Placebo-Controlled Phase II Trial (MAyflOwer RoAD)
Journal of Alzheimer's Disease, ISSN: 18758908 13872877
Stephane Nave; Rachelle S. Doody; Mercè Boada; Timo Grimmer; Juha-Matti Savola; Paul Delmar; Meike Pauly-Evers; Tania Nikolcheva; Christian Czech; Edilio Borroni; Benedicte Ricci; Juergen Dukart; Marie Mannino; Tracie Carey; Emma Moran; Inma Gilaberte; Nicoletta Milani Muelhardt; Irene Gerlach; Luca Santarelli; Ostrowitzki; Fontoura; Krista Lanctôt
View on Scopus
Expression of protein disulfide isomerase family members correlates with tumor progression and patient survival in ovarian cancer
Oncotarget, ISSN: 19492553
Soma Samanta; Shuzo Tamura; Louis Dubeau; Paulette Mhawech-Fauceglia; Yohei Miyagi; Hisamori Kato; Rich Lieberman; Ronald J. Buckanovich; Yvonne G. Lin; Nouri Neamati
View on Scopus
Integrated lead optimization: Translational models as we advance toward the clinic
AAPS Advances in the Pharmaceutical Sciences Series, ISSN: 2210738X 22107371
Bianca M. Liederer; Xingrong Liu; Simon Wong; Daniel R Mudra
View on Scopus
Ubiquitin in cell-cycle regulation and dysregulation in cancer
Annual Review of Cancer Biology, ISSN: 24723428
Natalie A. Borg; Vishva M. Dixit
View on Scopus
Utilization of In Vitro Neurotoxicity Models in Pre-Clinical Toxicity Assessment
Stem Cells in Toxicology and Medicine,
Karin Staflin; Misner; Donna M. Dambach
View on Scopus
IL-13 is a therapeutic target in radiation lung injury
Scientific Reports, ISSN: 20452322
Su I. Chung; Jason A. Horton; Thirumalai R. Ramalingam; Ayla O. White; Eun Joo Chung; Kathryn E. Hudak; Bradley T. Scroggins; Joseph R. Arron; Thomas A. Wynn; Deborah E. Citrin
View on Scopus
Structure of crenezumab complex with aβ shows loss of β-hairpin
Scientific Reports, ISSN: 20452322
Ultsch; Bing Li; Till Maurer; Mary Mathieu; Oskar Adolfsson; Andreas Muhs; Andrea Pfeifer; Maria Pihlgren; Travis W. Bainbridge; Mike Reichelt; James A. Ernst; Eigenbrot; Fuh; Jasvinder K. Atwal; Ryan J. Watts; Weiru Wang
View on Scopus
Characterization of chain pairing variants of bispecific IgG Expressed in a single host cell by high-resolution native and denaturing mass spectrometry
Analytical Chemistry, ISSN: 15206882 00032700
Luis Schachner; Guanghui Han; Michael Dillon; Jianhui Zhou; Luke McCarty; Diego Ellerman; Yiyuan Yin; Christoph Spiess; Jennie R. Lill; Paul J. Carter; Wendy N. Sandoval
View on Scopus
Rhodium(III)-Catalyzed C-H Functionalization of 1-(2H)-Phthalazinones at C8
Journal of Organic Chemistry, ISSN: 15206904 00223263
Malcolm P. Huestis
View on Scopus
Transition-Metal-Free Synthesis of Tertiary Aminocyclopropanes
Organic Letters, ISSN: 15237052 15237060
Patrick Cyr; Alexandre Côté-Raiche; Sarah M. Bronner
View on Scopus
Integrated genomic analysis of colorectal cancer progression reveals activation of EGFR through demethylation of the EREG promoter
Oncogene, ISSN: 14765594 09509232
Xueping Qu; Thomas Sandmann; Frierson; Ling Fu; Eloisa Fuentes; Kimberly Walter; Kwame Okrah; Rumpel; Moskaluk; Shan Lu; Wang; Richard Bourgon; Elicia M. Penuel; Andrea Pirzkall; Lukas Amler; Lackner; Tabernero; Garret M. Hampton; Omar Kabbarah
View on Scopus
Phase Ib study of duligotuzumab (MEHD7945A) plus cisplatin/5-fluorouracil or carboplatin/paclitaxel for first-line treatment of recurrent/metastatic squamous cell carcinoma of the head and neck
Cancer, ISSN: 10970142 0008543X
Antonio Jimeno; Jean-Pascal Machiels; Lori Wirth; Pol Specenier; Tanguy Y. Seiwert; Feby Mardjuadi; Xiaodong Wang; Amy V. Kapp; Stephanie Royer-Joo; Elicia M. Penuel; Bruce Mccall; Andrea Pirzkall; Paul M. Clement
View on Scopus
Impact of blood-brain barrier integrity on tumor growth and therapy response in brain metastases
Clinical Cancer Research, ISSN: 15573265 10780432
Matthias Osswald; Jonas Blaes; Yunxiang Liao; Gergely Solecki; Miriam Gömmel; Anna S. Berghoff; Laurent Salphati; Jeffery J. Wallin; Phillips; Wick; Frank Winkler
View on Scopus
The molecular landscape of high-risk early breast cancer: Comprehensive biomarker analysis of a phase III adjuvant population
npj Breast Cancer, ISSN: 23744677
Wilson; Yu; Xuyang Lu; Jill M. Spoerke; Yuanyuan Xiao; Carol O’brien; Heidi Savage; Huw; Wei Zou; Koeppen; William F. Forrest; Jane Fridlyand; Ling Fu; Rachel Tam; Erica Schleifman; Teiko Sumiyoshi; Luciana L. Molinero; Garret M. Hampton; O'Shaughnessy; Lackner
View on Scopus
Communicating laboratory test results for rheumatoid factor: What do patients and physicians want?
Patient Preference and Adherence, ISSN: 1177889X
Ariella Kelman; Caroline O. Robinson; Elisenda Cochin; Nina J. Ahluwalia; Julia Braverman; Emil Chiauzzi; Kristina Simacek
View on Scopus
ULK1-mediated phosphorylation of ATG14 promotes autophagy and is impaired in Huntington's disease models
Molecular Neurodegeneration, ISSN: 17501326
Mitchell S. Wold; Junghyun Lim; Véronik Lachance; Zhiqiang Deng; Zhenyu Yue
View on Scopus
Discovery of a Potent and Selective in Vivo Probe (GNE-272) for the Bromodomains of CBP/EP300
Journal of Medicinal Chemistry, ISSN: 15204804 00222623
Terry Crawford; F. Anthony Romero; Kwong Wah Lai; Vickie Tsui; Alexander M. Taylor; Gladys De Leon Boenig; Cameron Noland; Jeremy Murray; Justin Ly; Edna F. Choo; Thomas Hunsaker; Emily Chan; Mark Merchant; Samir Kharbanda; Karen Gascoigne; Susan Kaufman; Beresini; Jiangpeng Liao; Wenfeng Liu; Kevin Chen; Zhongguo Chen; Andrew R. Conery; Alexandre Côté; Hariharan Jayaram; Ying Jiang; James R. Kiefer; Tracy L. Kleinheinz; Yingjie Li; Jonathan M. Maher; Eneida Pardo; Florence Poy; Kerry L. Spillane; Fei Wang; Jian Wang; Xiaocang Wei; Zhaowu Xu; Zhongya Xu; Ivana Yen; Laura E. Zawadzke; Xiaoyu Zhu; Steve Bellon; Richard T Cummings; Andrea G Cochran; Brian K Albrecht; Steven Magnuson
View on Scopus
Custom-designed affinity capture LC-MS F(ab′)2 assay for biotransformation assessment of site-specific antibody drug conjugates
Analytical Chemistry, ISSN: 15206882 00032700
Dian Su; Carl Ng; Mehraban Khosraviani; Shang-Fan Yu; Ely Cosino; Surinder Kaur; Keyang Xu
View on Scopus
Automated affinity capture and on-tip digestion to accurately quantitate in vivo deamidation of therapeutic antibodies
Analytical Chemistry, ISSN: 15206882 00032700
John C. Tran; Daniel Tran; Amy Hilderbrand; Nisana Andersen; Tao Huang; Karin Reif; Isidro Hötzel; Stefanich; Yichin Liu; Jianyong Wang
View on Scopus
Acid-base interactions in amorphous solid dispersions of lumefantrine prepared by spray-drying and hot-melt extrusion using X-ray photoelectron spectroscopy
International Journal of Pharmaceutics, ISSN: 18733476 03785173
Yang Song; Dmitry Zemlyanov; Xin Chen; Ziyang Su; Haichen Nie; Joseph W. Lubach; Daniel Smith; Stephen Byrn; Rodolfo Pinal
View on Scopus
Predicting Passive Permeability of Drug-like Molecules from Chemical Structure: Where Are We?
Molecular Pharmaceutics, ISSN: 15438392 15438384
Broccatelli; Laurent Salphati; Emile G. Plise; Jonathan Cheong; Alberto Gobbi; Man-Ling Lee; Ignacio Aliagas
View on Scopus
The Yersinia pestis Effector YopM Inhibits Pyrin Inflammasome Activation
PLoS Pathogens, ISSN: 15537374 15537366
Dmitry Ratner; M. Pontus A. Orning; Megan K. Proulx; Donghai Wang; Mikhail A. Gavrilin; Mark D. Wewers; Alnemri; Peter F. Johnson; Bettina L. Lee; Joan Mecsas; Nobuhiko Kayagaki; Jon D. Goguen; Egil Lien
View on Scopus
Survival in patients with non-metastatic breast cancer treated with adjuvant trastuzumab in clinical practice
SpringerPlus, ISSN: 21931801
Christopher Gallagher; Kenneth More; Anthony Masaquel; Tripthi V. Kamath; Annie Guérin; Raluca Ionescu-Ittu; Roy Nitulescu; Marjolaine Gauthier-Loiselle; Nicholas Sicignano; Elizabeth Butts; Eric Q. Wu; Brian Barnett
View on Scopus
© 2024 Genentech, Inc. All rights reserved. This site is intended for US residents only.