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DISPLAYING 5001 - 5050 OF 15578 RESULTS

Atezolizumab (atezo) in platinum (plat)-treated locally advanced/metastatic urothelial carcinoma (mUC): Updated OS, safety and biomarkers from the Ph II IMvigor210 study
Annals of Oncology, ISSN: 15698041 09237534
Yohann Loriot; Jonathan E. Rosenberg; Thomas Powles; Andrea Necchi; Syed Hussain; Morales; Margitta M. Retz; Günter Niegisch; Ignacio Durán; Christine Théodore; Jose Luis Perez-Gracia; Grande Pulido; AnnChristine Thåström; Bradford Danner; Sanjeev Mariathasan; Oyewale Abidoye; Michiel S Van Der Heijden
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Second-line metastatic urothelial carcinoma treatment and survival in real-world patients in the US
Annals of Oncology, ISSN: 15698041 09237534
Sumanta Kumar Pal; Matthew D. Galsky; Shih Wen Lin; Sarika Ogale; Marko Zivkovic; Simpson; Christina L. Derleth; Guru Sonpavde
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PTEN loss as a predictive biomarker for the Akt inhibitor ipatasertib combined with abiraterone acetate in patients with metastatic castration-resistant prostate cancer (mCRPC)
Annals of Oncology, ISSN: 15698041 09237534
De Bono; De Giorgi; Christophe Massard; Sergio Bracarda; Nava Rodrigues; Ivo Kocak; Albert Font; J. Arranz Arija; Shih; George Daniel Radavoi; Yu; Wai Y. Chan; Steven Gendreau; Zhang; Ruth Riisnaes; Matthew Wongchenko; Daniel Maslyar; Viorel Jinga
View on Scopus
A real-world study of patterns of Bacillus Calmette-Guerin (BCG) use and associated adverse events (AEs) in non-muscle invasive bladder cancer (NMIBC) patients in the United States
Annals of Oncology, ISSN: 15698041 09237534
Kathleen Wilson; Elisabetta Malangone-Monaco; Sacha Satram-Hoang; Diakun; Lin; Darren Tayama; Sarika Ogale
View on Scopus
Safety, clinical activity and biomarkers of atezolizumab (atezo) in advanced ovarian cancer (OC)
Annals of Oncology, ISSN: 15698041 09237534
Jeffery R. Infante; Fadi S. Braiteh; Leisha A. Emens; Ani Balmanoukian; Ana Oaknin; Yan Wang; Liu; Luciana L. Molinero; Marcella Fassò; Carol E. O'Hear; Michael S. Gordon
View on Scopus
A retrospective, real-world study of treatment patterns and outcomes among metastatic urothelial cancer (mUC) patients in the United States
Annals of Oncology, ISSN: 15698041 09237534
Elisabetta Malangone-Monaco; Sacha Satram-Hoang; Kathleen Wilson; Helen Varker; Lin; Darren Tayama; Sarika Ogale
View on Scopus
Primary analysis from OAK, a randomized phase III study comparing atezolizumab with docetaxel in 2L/3L NSCLC
Annals of Oncology, ISSN: 15698041 09237534
Fabrice Barlesi; Park; Fortunato Ciardiello; Joachim Von Pawel; Shirish M. Gadgeel; Toyoaki Hida; Dariusz M Kowalski; Manuel Cobo Dols; Diego L Cortinovis; Joseph W. Leach; Jonathan Polikoff; David R. Gandara; Carlos H. Barrios; Daniel S. Chen; Pei He; Marcin Kowanetz; Ballinger; Waterkamp; Alan Sandler; Achim Rittmeyer
View on Scopus
A phase I study evaluating DLYE5953A, an antibody-drug conjugate targeting the tumor-associated antigen lymphocyte antigen 6 complex locus E (Ly6E), in patients (Pts) with solid tumors
Annals of Oncology, ISSN: 15698041 09237534
Shanu Modi; Joseph Paul Eder; Patricia M. LoRusso; Colin D. Weekes; Sarat Chandarlapaty; Tolaney; McLaughlin; D. Ross Camidge; Chang; Denise Nazzal; Chen; Schuth; Flavia Brunstein; Darbonne; W. Michael Flanagan; Alexander Ungewickell; Geoffrey I. Shapiro
View on Scopus
First-line cobimetinib (C) + paclitaxel (P) in patients (pts) with advanced triple-negative breast cancer (TNBC): Updated results and tumoral immune cell infiltration data from the phase 2 COLET study
Annals of Oncology, ISSN: 15698041 09237534
David W. Miles; Kim; Velu; Garcia-Saenz; Elizabeth Tan-Chiu; Sohn; Luc Dirix; Vanˇásek; Borms; J. Ilgado De Mingorance; Liu; Moezi; Kozloff; Joseph Sparano; Xu; Yan; Matthew Wongchenko; Brian Simmons; Virginia McNally; Adam Brufsky
View on Scopus
The SP142 PD-L1 IHC assay for atezolizumab (atezo) reflects pre-existing immune status in NSCLC and correlates with PD-L1 mRNA
Annals of Oncology, ISSN: 15698041 09237534
Williams; Marcin Kowanetz; Koeppen; Zachary Boyd; Edward E. Kadel III; Dustin Smith; Mark L. McCleland; Wei Zou; Priti Hegde
View on Scopus
SANDPIPER: Phase III study of the PI3-kinase (PI3K) inhibitor taselisib (GDC-0032) plus fulvestrant in patients (pts) with oestrogen receptor (ER)-positive, HER2-negative locally advanced or metastatic breast cancer (BC) enriched for pts with PIK3CA-mutant tumours
Annals of Oncology, ISSN: 15698041 09237534
Baselga; Cortes Castan; De Laurentiis; Diéras; Nadia Harbeck; Hsu; Huan Jin; Frauke Schimmoller; Wilson; Im; William Jacot; Ian E. Krop; Sunil Verma
View on Scopus
Analytic validation of a clinical circulating tumor DNA assay for patients with solid tumors
Annals of Oncology, ISSN: 15698041 09237534
Phillip J. Stephens; Travis A. Clark; Mark Kennedy; He; Young; Mandy Zhao; Michael Coyne; Virginia Breese; Young; Shan Zhong; Mark Bailey; Bernard Fendler; Vincent A. Miller; Erica Schleifman; Peters; Geoff A. Otto; Doron Lipson; Jeffrey S. Ross
View on Scopus
Genomic features of complete responders (CR) versus fast progressors (PD) in patients with BRAFV600-mutated metastatic melanoma treated with cobimetinib + vemurafenib or vemurafenib alone
Annals of Oncology, ISSN: 15698041 09237534
Yan; Caroline Robert; James Larkin; Paolo A. Ascierto; Brigitte Dréno; Michele Maio; Claus Garbe; Paul B. Chapman; Jeffrey A. Sosman; Matthew Wongchenko; Jessie Hsu; Ilsung Chang; Ivor Caro; Isabelle Rooney; McArthur; Antoni Ribas
View on Scopus
Clinical activity, safety and predictive biomarkers results from a phase Ia atezolizumab (atezo) trial in extensive-stage small cell lung cancer (ES-SCLC)
Annals of Oncology, ISSN: 15698041 09237534
Lecia V. Sequist; Chiang; Gilbert; Michael S. Gordon; Paul Conkling; Thompson; Marcoux; Scott J. Antonia; Liu; David S. Shames; Ariel Lopez-Chavez; Carol E. O'Hear; Marcella Fassò; Scott Gettinger
View on Scopus
Prognostic subgroups and impact of treatment for post-progression overall survival (ppOS) in patients (pts) with BRAFV600-mutated metastatic melanoma treated with dacarbazine (DTIC) or vemurafenib (VEM) ± cobimetinib (COBI): A pooled analysis
Annals of Oncology, ISSN: 15698041 09237534
Paolo A. Ascierto; Antoni Ribas; James Larkin; McArthur; Karl Lewis; Axel Hauschild; Keith Flaherty; Edward McKenna; Qian Zhu; Yong Mun; Brigitte Dréno
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Efficacy and safety of cobimetinib (cobi) and atezolizumab (atezo) in an expanded phase 1b study of microsatellite-stable (MSS) metastatic colorectal cancer (mCRC)
Annals of Oncology, ISSN: 15698041 09237534
Jayesh Desai; Hong; Kim; Kim; Han; Bang; Chee; Heong; McRee; Laura Q.M. Chow; Eunice Kwak; Jeffery R. Infante; Jeffery J. Wallin; M. Das Thakur; Mwawasi; Paul Foster; Edward Cha; Bendell
View on Scopus
Preliminary safety and clinical activity of atezolizumab combined with cobimetinib and vemurafenib in BRAF V600-mutant metastatic melanoma
Annals of Oncology, ISSN: 15698041 09237534
Patrick Hwu; Omid Hamid; Rene Gonzalez; Jeffery R. Infante; Manish R. Patel; F. Stephen Hodi; Karl Lewis; Jeffery J. Wallin; Mwawasi; Edward Cha; Nicole A. Richie; Ballinger; Richard Sullivan
View on Scopus
Tumor mutation load assessed by FoundationOne (FM1) is associated with improved efficacy of atezolizumab (atezo) in patients with advanced NSCLC
Annals of Oncology, ISSN: 15698041 09237534
Marcin Kowanetz; Wei Zou; David S. Shames; Cummings; Naiyer A. Rizvi; Alexander Spira; Garrett M Frampton; Vincent Leveque; Susan Flynn; Mocci; Geetha Shankar; Roel Funke; Ballinger; Waterkamp; Alan Sandler; Garret M. Hampton; Lukas Amler; Priti Hegde; Matthew D. Hellmann
View on Scopus
A real-world study of patterns of Bacillus Calmette-Guerin (BCG) use and associated adverse events (AEs) in non-muscle invasive bladder cancer (NMIBC) patients in the United States
Annals of Oncology, ISSN: 15698041 09237534
Kathleen Wilson; Elisabetta Malangone-Monaco; Sacha Satram-Hoang; Diakun; Shih-Wen Lin; Darren Tayama; Sarika Ogale
View on Scopus
Tumor mutation load assessed by FoundationOne (FM1) is associated with improved efficacy of atezolizumab (atezo) in patients with advanced NSCLC
Annals of Oncology, ISSN: 15698041 09237534
Marcin Kowanetz; Wei Zou; David S. Shames; Cummings; Naiyer A. Rizvi; Alexander Spira; Garrett M Frampton; Vincent Leveque; Susan Flynn; Mocci; Geetha Shankar; Roel Funke; Ballinger; Waterkamp; Alan Sandler; Garret M. Hampton; Lukas Amler; Priti Hegde; Matthew D. Hellmann
View on Scopus
A retrospective, real-world study of treatment patterns and outcomes among metastatic urothelial cancer (mUC) patients in the United States
Annals of Oncology, ISSN: 15698041 09237534
Elisabetta Malangone-Monaco; Sacha Satram-Hoang; Kathleen Wilson; Helen Varker; Shih-Wen Lin; Darren Tayama; Sarika Ogale
View on Scopus
Safety, clinical activity and biomarkers of atezolizumab (atezo) in advanced ovarian cancer (OC)
Annals of Oncology, ISSN: 15698041 09237534
Jeffery R. Infante; Fadi S. Braiteh; Leisha A. Emens; Ani Balmanoukian; Ana Oaknin; Yan Wang; Bo Liu; Luciana L. Molinero; Marcella Fassò; Carol E. O'Hear; Michael S. Gordon
View on Scopus
Analytic validation of a clinical circulating tumor DNA assay for patients with solid tumors
Annals of Oncology, ISSN: 15698041 09237534
Phillip J. Stephens; Travis A. Clark; Mark Kennedy; He; Young; Mandy Zhao; Michael Coyne; Virginia Breese; Young; Shan Zhong; Mark Bailey; Bernard Fendler; Vincent A. Miller; Erica Schleifman; Peters; Geoff A. Otto; Doron Lipson; Jeffrey S. Ross
View on Scopus
A phase I study evaluating DLYE5953A, an antibody-drug conjugate targeting the tumor-associated antigen lymphocyte antigen 6 complex locus E (Ly6E), in patients (Pts) with solid tumors
Annals of Oncology, ISSN: 15698041 09237534
Modi; Joseph Paul Eder; Patricia M. LoRusso; Colin D. Weekes; Sarat Chandarlapaty; Tolaney; McLaughlin; D. Ross Camidge; Chang; Denise Nazzal; Chen; Schuth; Flavia Brunstein; Darbonne; W. Michael Flanagan; Alexander Ungewickell; Geoffrey I. Shapiro
View on Scopus
PTEN loss as a predictive biomarker for the Akt inhibitor ipatasertib combined with abiraterone acetate in patients with metastatic castration-resistant prostate cancer (mCRPC)
Annals of Oncology, ISSN: 15698041 09237534
De Bono; Ugo De Giorgi; Christophe Massard; Sergio Bracarda; Nava Rodrigues; Ivo Kocak; Albert Font; Jose Angel Arranz Arija; Shih; George Daniel Radavoi; Wei Yu; Wai Y. Chan; Steven Gendreau; Liangxuan Zhang; Ruth Riisnaes; Matthew Wongchenko; Daniel Maslyar; Viorel Jinga
View on Scopus
Primary analysis from OAK, a randomized phase III study comparing atezolizumab with docetaxel in 2L/3L NSCLC
Annals of Oncology, ISSN: 15698041 09237534
Fabrice Barlesi; Park; Fortunato Ciardiello; Joachim Von Pawel; Shirish M. Gadgeel; Hida; Dariusz M Kowalski; Manuel Cobo Dols; Diego L Cortinovis; Joseph W. Leach; Jonathan Polikoff; David R. Gandara; Carlos H. Barrios; Chen; Pei He; Marcin Kowanetz; Ballinger; Waterkamp; Alan Sandler; Achim Rittmeyer
View on Scopus
First-line cobimetinib (C) + paclitaxel (P) in patients (pts) with advanced triple-negative breast cancer (TNBC): Updated results and tumoral immune cell infiltration data from the phase 2 COLET study
Annals of Oncology, ISSN: 15698041 09237534
David W. Miles; Sung-Bae Kim; Velu; Garcia-Saenz; Elizabeth Tan-Chiu; Sohn; Luc Dirix; Vanˇásek; Borms; J. Ilgado De Mingorance; Liu; Moezi; Kozloff; Joseph Sparano; Xu; Yibing Yan; Matthew Wongchenko; Brian Simmons; Virginia McNally; Adam Brufsky
View on Scopus
Atezolizumab (atezo) in platinum (plat)-treated locally advanced/metastatic urothelial carcinoma (mUC): Updated OS, safety and biomarkers from the Ph II IMvigor210 study
Annals of Oncology, ISSN: 15698041 09237534
Yohann Loriot; Jonathan E. Rosenberg; Thomas Powles; Andrea Necchi; Syed Hussain; Morales; Margitta M. Retz; Günter Niegisch; Ignacio Durán; Christine Théodore; Jose Luis Perez-Gracia; Grande Pulido; AnnChristine Thåström; Bradford Danner; Sanjeev Mariathasan; Oyewale Abidoye; Michiel S Van Der Heijden
View on Scopus
Genomic features of complete responders (CR) versus fast progressors (PD) in patients with BRAFV600-mutated metastatic melanoma treated with cobimetinib + vemurafenib or vemurafenib alone
Annals of Oncology, ISSN: 15698041 09237534
Yibing Yan; Caroline Robert; James Larkin; Paolo A. Ascierto; Brigitte Dréno; Michele Maio; Claus Garbe; Paul B. Chapman; Jeffrey A. Sosman; Matthew Wongchenko; Hsu; Chang; Ivor Caro; Isabelle Rooney; McArthur; Antoni Ribas
View on Scopus
SANDPIPER: Phase III study of the PI3-kinase (PI3K) inhibitor taselisib (GDC-0032) plus fulvestrant in patients (pts) with oestrogen receptor (ER)-positive, HER2-negative locally advanced or metastatic breast cancer (BC) enriched for pts with PIK3CA-mutant tumours
Annals of Oncology, ISSN: 15698041 09237534
Baselga; Cortes Castan; De Laurentiis; Diéras; Nadia Harbeck; Jerry Y. Hsu; Jin; Frauke Schimmoller; Wilson; Im; William Jacot; Ian E. Krop; Sunil Verma
View on Scopus
Clinical activity, safety and predictive biomarkers results from a phase Ia atezolizumab (atezo) trial in extensive-stage small cell lung cancer (ES-SCLC)
Annals of Oncology, ISSN: 15698041 09237534
Lecia V. Sequist; Chiang; Gilbert; Michael S. Gordon; Paul Conkling; Thompson; Marcoux; Scott J. Antonia; Bo Liu; David S. Shames; Ariel Lopez-Chavez; Carol E. O'Hear; Marcella Fassò; Scott Gettinger
View on Scopus
The SP142 PD-L1 IHC assay for atezolizumab (atezo) reflects pre-existing immune status in NSCLC and correlates with PD-L1 mRNA
Annals of Oncology, ISSN: 15698041 09237534
Williams; Marcin Kowanetz; Koeppen; Zachary Boyd; Edward E. Kadel III; Dustin Smith; Mark L. McCleland; Wei Zou; Priti Hegde
View on Scopus
Preliminary safety and clinical activity of atezolizumab combined with cobimetinib and vemurafenib in BRAF V600-mutant metastatic melanoma
Annals of Oncology, ISSN: 15698041 09237534
Patrick Hwu; Omid Hamid; Rene Gonzalez; Jeffery R. Infante; Manish R. Patel; F. Stephen Hodi; Karl Lewis; Jeffery J. Wallin; Mwawasi; Edward Cha; Nicole A. Richie; Ballinger; Ryan J. Sullivan
View on Scopus
Minimizing CYP2C9 Inhibition of Exposed-Pyridine NAMPT (Nicotinamide Phosphoribosyltransferase) Inhibitors
Journal of Medicinal Chemistry, ISSN: 15204804 00222623
Mark Zak; Po-Wai Yuen; Xiongcai Liu; Snahel Patel; Deepak Sampath; Jason Oeh; Bianca M. Liederer; Weiru Wang; Thomas O'Brien; Yang Xiao; Nicholas J. Skelton; Rongbao Hua; Jasleen K. Sodhi; Yunli Wang; Lei Zhang; Guiling Zhao; Xiaozhang Zheng; Yen-Ching Ho; Kenneth W. Bair; Peter Dragovich
View on Scopus
Developing HSCs become Notch independent by the end of maturation in the AGM region
Blood, ISSN: 15280020 00064971
Céline Souilhol; Javier G. Lendinez; Stanislav Rybtsov; Fiona Murphy; Heather Wilson; David Hills; Antoniana Batsivari; Anahí Binagui-Casas; Alison C. McGarvey; H. Robson MacDonald; Kageyama; Christian W. Siebel; Suling Zhao; Alexander Medvinsky
View on Scopus
Structural Characterization of Cross-Linked Species in Trastuzumab Emtansine (Kadcyla)
Bioconjugate Chemistry, ISSN: 15204812 10431802
Yan Chen; Michael Kim; Laura Zheng; Galahad Deperalta; Fred Jacobson
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Interfering with the chronic immune response rescues chronic degeneration after traumatic brain injury
Journal of Neuroscience, ISSN: 15292401 02706474
Ali Ertürk; Susanne Mentz; Erik E. Stout; Maj Hedehus; Sara L. Dominguez; Lisa Neumaier; Franziska Krammer; Gemma Llovera; Karpagam Srinivasan; David V. Hansen; Arthur Liesz; Kimberly Scearce-Levie; Morgan Sheng
View on Scopus
Preparation of 2-Azabicyclo[21.1]hexane Hydrochloride
Synlett, ISSN: 14372096 09365214
Haili Liao; Aimin Li; Xingsong Chen; Kun Liang; Yang Shen; Qingfeng Liang; Kewei Xu; Daniel G. Shore; Elisia Villemure; Michael Siu; Malcolm P. Huestis
View on Scopus
Synthesis of Fused Imidazole-Containing Ring Systems via Dual Oxidative Amination of C(sp3)-H Bonds
Journal of Organic Chemistry, ISSN: 15206904 00223263
Georgette M. Castanedo; Yanzhou Liu; James J. Crawford; Marie-Gabrielle Braun
View on Scopus
Discovery of oxa-sultams as RORc inverse agonists showing reduced lipophilicity, improved selectivity and favorable ADME properties
Bioorganic and Medicinal Chemistry Letters, ISSN: 14643405 0960894X
Olivier René; Benjamin P. Fauber; Adrian Barnard; Kerry Chapman; Yuzhong Deng; Celine Eidenschenk; Christine Everett; Alberto Gobbi; Adam R. Johnson; Hank La; Maxine Norman; Gary Salmon; Susan Summerhill; Harvey Wong
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Recent progress on nuclear receptor RORγ modulators
Bioorganic and Medicinal Chemistry Letters, ISSN: 14643405 0960894X
Patrick Cyr; Sarah M. Bronner; James J. Crawford
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Design and evaluation of 1,7-naphthyridones as novel KDM5 inhibitors
Bioorganic and Medicinal Chemistry Letters, ISSN: 14643405 0960894X
Sharada Labadie; Peter Dragovich; Richard T Cummings; Gauri Deshmukh; Amy Gustafson; Ning Han; Jean-Christophe Harmange; James R. Kiefer; Yue Li; Jun Liang; Bianca M. Liederer; Yichin Liu; Wanda Manieri; Weifeng Mao; Lesley J. Murray; Daniel F. Ortwine; Patrick Trojer; Erica Vanderporten; Maia Vinogradova; Li Wen
View on Scopus
Generation and Protective Ability of Influenza Virus-Specific Antibody-Dependent Cellular Cytotoxicity in Humans Elicited by Vaccination, Natural Infection, and Experimental Challenge
Journal of Infectious Diseases, ISSN: 15376613 00221899
Sinthujan Jegaskanda; Catherine Luke; Heather D. Hickman; Mark Y. Sangster; Wendy F. Wieland-Alter; Jacqueline McBride; Jon W. Yewdell; Peter Wright; John Treanor; Carrie M. Rosenberger; Kanta Subbarao
View on Scopus
A phase i dose-escalation study evaluating the safety tolerability and pharmacokinetics of CUDC-427, a potent, oral, monovalent IAP antagonist, in patients with refractory solid tumors
Clinical Cancer Research, ISSN: 15573265 10780432
Anthony W. Tolcher; Bendell; Kyriakos P. Papadopoulos; Howard A. Burris; Amita Patnaik; Wayne J. Fairbrother; Harvey Wong; Nageshwar Budha; Darbonne; Franklin V. Peale Jr.; Michael Mamounas; Stephanie Royer-Joo; Ron Yu; Chia C. Portera; Jeffery R. Infante
View on Scopus
Validation of a treatment satisfaction questionnaire in non-hodgkin lymphoma: Assessing the change from intravenous to subcutaneous administration of rituximab
Patient Preference and Adherence, ISSN: 1177889X
Christina Theodore-Oklota; Louise Humphrey; Christof Wiesner; Gabriel Schnetzler; Stacie Hudgens; Alicyn K. Campbell
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Fast and Efficient non-reduced Lys-C digest using pressure cycling technology for antibody disulfide mapping by LC–MS
Journal of Pharmaceutical and Biomedical Analysis, ISSN: 1873264X 07317085
Ying Cheng; Yonghong Chen; X. Christopher Yu
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Rapid, semi-automated protein terminal characterization using ISDetect
Nature Biotechnology, ISSN: 15461696 10870156
Corey Bakalarski; Yutian Gan; Ingrid E. Wertz; Jennie R. Lill; Wendy N. Sandoval
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Prolyl-isomerase Pin1 controls Notch3 protein expression and regulates T-ALL progression
Oncogene, ISSN: 14765594 09509232
Franciosa; Diluvio; Del Gaudio; Giuli; Palermo; Grazioli; Campese; Talora; Bellavia; D'Amati; Besharat; Nicoletti; Christian W. Siebel; Lisa Choy; Rustighi; G Del Sal; Screpanti; Checquolo
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High cell-surface density of HER2 deforms cell membranes
Nature Communications, ISSN: 20411723
Inhee Chung; Mike Reichelt; Lily Shao; Robert W. Akita; Koeppen; Linda Rangell; Gabriele Schaefer; Ira Mellman; Mark X. Sliwkowski
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Characterization of the pH and temperature in the rabbit, pig, and monkey eye: Key parameters for the development of long-acting delivery ocular strategies
Molecular Pharmaceutics, ISSN: 15438392 15438384
Florence Lorget; Audrey Parenteau; Michel Carrier; Daniel Lambert; Ana Gueorguieva; Chris Schuetz; Vlad Bantseev; Evan A Thackaberry
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