Scientists / Publications

Publications

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DISPLAYING 6201 - 6250 OF 15578 RESULTS

Treatment Patterns and Comparative Effectiveness in Elderly Diffuse Large B-Cell Lymphoma Patients: A Surveillance, Epidemiology, and End Results-Medicare Analysis
Oncologist, ISSN: 1549490X 10837159
Paul A. Hamlin; Sacha Satram-Hoang; Carolina Reyes; Khang Q. Hoang; Sridhar R. Guduru; Sandra Skettino
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SOX17 links gut endoderm morphogenesis and germ layer segregation
Nature Cell Biology, ISSN: 14764679 14657392
Manuel Viotti; Sonja Nowotschin; Anna-Katerina Hadjantonakis
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Proteome-wide light/dark modulation of thiol oxidation in cyanobacteria revealed by quantitative site-specific redox proteomics
Molecular and Cellular Proteomics, ISSN: 15359484 15359476
Jia Guo; Amelia Y. Nguyen; Ziyu Dai; Dian Su; Matthew J. Gaffrey; Ronald J. Moore; Jon M. Jacobs; Matthew E. Monroe; Richard D. Smith; David W. Koppenaal; Himadri B. Pakrasi; Wei-Jun Qian
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Practical permeability-based hepatic clearance classification system (HepCCS) in drug discovery
Future Medicinal Chemistry, ISSN: 17568927 17568919
Peter W. Fan; Yang Song; Leonid M. Berezhkovskiy; Jonathan Cheong; Emile G. Plise; S. Cyrus Khojasteh
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Visualization of protein sequence features using JavaScript and SVG with pViz.js
Bioinformatics, ISSN: 14602059 13674803
Kiran Mukhyalay; Alexandre Masselot
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Vision-related function after ranibizumab treatment for diabetic macular edema: Results from RIDE and RISE
Ophthalmology, ISSN: 15494713 01616420
Neil M. Bressler; Rohit Varma; Ivan J. Suñer; Chantal M. Dolan; James Ward; Jason S. Ehrlich; Shoshana Colman; Adam Turpcu
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Systemic pharmacokinetics following intravitreal injections of ranibizumab, bevacizumab or aflibercept in patients with neovascular amd
British Journal of Ophthalmology, ISSN: 14682079 00071161
Robert L. Avery; Alessandro A. Castellarin; Nathan C. Steinle; Dilsher S. Dhoot; Dante Joseph Pieramici; Robert See; Stephen Couvillion; MA'An A. Nasir; Melvin D. Rabena; Kha Le; Mauricio Maia; Jennifer Visich
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2014 White Paper on recent issues in bioanalysis: A full immersion in bioanalysis (Part 3-LBA and immunogenicity)
Bioanalysis, ISSN: 17576199 17576180
Lauren Stevenson; Lakshmi Amaravadi; Heather Myler; Laura Salazar-Fontana; Boris Gorovits; Susan Kirshner; Li Xue; Fabio Garofolo; Stephen C. Alley; Theingi Thway; Alison Joyce; Surendra Bansal; Chris Beaver; Annik Bergeron; Xiao-Yan Cai; Laura Cojocaru; Binodh DeSilva; Isabelle Dumont; Eric Fluhler; Stephanie Fraser; Dominique Gouty; Swati Gupta; Sam Haidar; Roger Hayes; Benno Ingelse; Akiko Ishii-Watabe; Surinder Kaur; Lindsay King; Omar Laterza; Sheldon Leung; Ann Lévesque; Mark Ma; Corinne Petit-Frere; Renuka Pillutla; Mark Rose; Gary Schultz; John Smeraglia; Steven J. Swanson; Albert Torri; Faye Vazvaei; Jason Wakelin-Smith; Amanda Wilson; Eric Woolf; Tong-Yuan Yang
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Impact of symptom burden on work-related abilities in patients with locally recurrent or metastatic breast cancer: Results from a substudy of the VIRGO observational cohort study
Breast, ISSN: 15323080 09609776
Charles S. Cleeland; Musa Mayer; Nancy A. Dreyer; Yeun Mi Yim; Elaine B. Yu; Zhaohui Su; Yong Mun; Jeff A. Sloan; Peter A. Kaufman
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2014 White Paper on recent issues in bioanalysis: A full immersion in bioanalysis (Part 2-hybrid LBA/LCMS, ELN & regulatory agencies' input)
Bioanalysis, ISSN: 17576199 17576180
Dawn Dufield; Hendrik Neubert; Fabio Garofolo; Leo Kirkovsky; Lauren Stevenson; Isabelle Dumont; Surinder Kaur; Keyang Xu; Stephen C. Alley; Matthew Szapacs; Mark Arnold; Surendra Bansal; Sam Haidar; Jan Welink; Olivier Le Blaye; Jason Wakelin-Smith; Emma Whale; Akiko Ishii-Watabe; Mark Bustard; Noriko Katori; Lakshmi Amaravadi; Anne-Françoise Aubry; Chris Beaver; Annik Bergeron; Xiao-Yan Cai; Laura Cojocaru; Binodh DeSilva; Jeff Duggan; Eric Fluhler; Boris Gorovits; Swati Gupta; Roger Hayes; Stacy Ho; Benno Ingelse; Lindsay King; Ann Lévesque; Steve Lowes; Mark Ma; Adrien Musuku; Heather Myler; Timothy Olah; Shefali Patel; Mark Rose; Gary Schultz; John Smeraglia; Steven J. Swanson; Albert Torri; Faye Vazvaei; Amanda Wilson; Eric Woolf; Li Xue; Tong-Yuan Yang
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Complement inhibition in cynomolgus monkeys by anti-factor D antigen-binding fragment for the treatment of an advanced form of dry age-related macular degeneration
Journal of Pharmacology and Experimental Therapeutics, ISSN: 15210103 00223565
Kelly M. Loyet; Jeremy Good; Teresa Davancaze; Lizette Sturgeon; Xiangdan Wang; Yang; Kha Le; Maureen Wong; Hass; Menno Van Lookeren Campagne; Peter Haughney; Alyssa M. Morimoto; Lisa A. Damico; Laura DeForge
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Willingness to pay to avoid metastatic breast cancer treatment side effects: results from a conjoint analysis
SpringerPlus, ISSN: 21931801
Deepa Lalla; Rashad Carlton; Eduardo Santos; Thomas Bramley; Anna D’Souza
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A novel CMKLR1 small molecule antagonist suppresses CNS autoimmune inflammatory disease
PLoS ONE, ISSN: 19326203
Kareem L. Graham; Jian V. Zhang; Susanna Lewén; Thomas M. Burke; Ton Dang; Maria Zoudilova; Raymond A. Sobel; Eugene C. Butcher; Brian A. Zabel
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TNFR1-activated NF-κB signal transduction: Regulation by the ubiquitin/proteasome system
Current Opinion in Chemical Biology, ISSN: 18790402 13675931
Ingrid E. Wertz
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Ultra-high-pressure liquid chromatography (UHPLC) in method development
TrAC - Trends in Analytical Chemistry, ISSN: 18793142 01659936
Michael W. Dong; Kelly Zhang
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Backbone cyclization of a recombinant cystine-knot peptide by engineered Sortase A
FEBS Letters, ISSN: 18733468 00145793
Karen Stanger; Till Maurer; Harini Kaluarachchi; Mary Coons; Yvonne Franke; Rami N. Hannoush
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Single-cell in situ imaging of palmitoylation in fatty-acylated proteins
Nature Protocols, ISSN: 17502799 17542189
Xinxin Gao; Rami N. Hannoush
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Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing
Nature, ISSN: 14764687 00280836
Mahesh Yadav; Suchit Jhunjhunwala; Qui Phung; Patrick J. Lupardus; Josh Tanguay; Stephanie M. Bumbaca; Christian Franci; Tommy K. Cheung; Jens Fritsche; Toni Weinschenk; Zora Modrusan; Ira Mellman; Jennie R. Lill; Lélia Delamarre
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MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer
Nature, ISSN: 14764687 00280836
Thomas Powles; Joseph Paul Eder; Gregg D. Fine; Fadi S. Braiteh; Yohann Loriot; Cristina Cruz; Joaquim Bellmunt; Howard A. Burris; Petrylak; Siew-Leng Teng; Xiaodong Shen; Zachary Boyd; Priti Hegde; Daniel S. Chen; Nicholas J. Vogelzang
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Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients
Nature, ISSN: 14764687 00280836
Roy S. Herbst; Jean-Charles Soria; Marcin Kowanetz; Gregg D. Fine; Omid Hamid; Michael S. Gordon; Jeffrey A. Sosman; David McDermott; John D. Powderly; Scott Gettinger; Holbrook E. K. Kohrt; Leora Horn; Donald Lawrence; Sandra Rost; Maya Leabman; Yuanyuan Xiao; Ahmad Mokatrin; Koeppen; Priti Hegde; Ira Mellman; Daniel S. Chen; F. Stephen Hodi
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Molecular simulations of the pairwise interaction of monoclonal antibodies
Journal of Physical Chemistry B, ISSN: 15205207 15206106
Mauro Lapelosa; Thomas W. Patapoff; Isidro E. Zarraga
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The blood-brain barrier's gut check
Science Translational Medicine, ISSN: 19466242 19466234
Nga Bien-Ly; Ryan J. Watts
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Evaluating Source Data Verification as a Quality Control Measure in Clinical Trials
Therapeutic Innovation and Regulatory Science, ISSN: 21684804 21684790
Nicole Sheetz; Brett Wilson; Joanne Benedict; Esther Huffman; Andy Lawton; Mark Travers; Patrick Nadolny; Stephen Young; Kyle Given; Lawrence Florin
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Drugs for macular degeneration
JAMA - Journal of the American Medical Association, ISSN: 15383598 00987484
Ivaylo Stoilov; Anne E. Fung; Roman G. Rubio
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Quantification of residual solvents in antibody drug conjugates using gas chromatography
Analytica Chimica Acta, ISSN: 18734324 00032670
Colin D. Medley; Jacob Kay; Yi Li; Jason Gruenhagen; Peter M. Yehl; Nik P. Chetwyn
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Bap1 is essential for kidney function and cooperates with Vhl in renal tumorigenesis
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 10916490 00278424
Shan-Shan Wang; Yi-Feng Gu; Nicholas Wolff; Karoliina Stefanius; Alana Christie; Anwesha Dey; Robert E. Hammer; Xian-Jin Xie; Dinesh Rakheja; Ivan Pedrosa; Thomas Carroll; Renée M. McKay; Payal Kapur; James Brugarolas
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A microRNA upregulated in asthma airway T cells promotes T H 2 cytokine production
Nature Immunology, ISSN: 15292916 15292908
Laura J. Simpson; Sana Patel; Nirav R. Bhakta; David F. Choy; Hans D. Brightbill; Xin Ren; Yanli Wang; Heather H. Pua; Dirk Baumjohann; Misty M. Montoya; Marisella Panduro; Kelly A. Remedios; Xiaozhu Huang; John V. Fahy; Joseph R. Arron; Prescott G. Woodruff; K. Mark Ansel
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Combined vemurafenib and cobimetinib in BRAF-mutated melanoma
New England Journal of Medicine, ISSN: 15334406 00284793
James Larkin; Paolo A. Ascierto; Brigitte Dréno; Victoria Atkinson; Gabriella Liszkay; Michele Maio; Mario Mandala; Lev Demidov; Daniil Stroyakovskiy; Luc Thomas; Luis De La Cruz-Merino; Caroline Dutriaux; Claus Garbe; Mika A. Sovak; Ilsung Chang; Nicholas Choong; Stephen P. Hack; McArthur; Antoni Ribas
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Regulation of neuronal gene expression and survival by basal NMDA receptor activity: A role for histone deacetylase 4
Journal of Neuroscience, ISSN: 15292401 02706474
Yelin Chen; Yuanyuan Wang; Zora Modrusan; Morgan Sheng; Joshua S. Kaminker
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Direct medical costs and resource use for treating central and branch retinal vein occlusion in commercially insured working-age and medicare populations
Retina, ISSN: 15392864 0275004X
Ivan J. Suñer; Jay Margolis; Kimberly Ruiz; Irwin Tran; Paul P. Lee
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Collateral vessel presence in branch and central retinal vein occlusions and their impact on visual acuity and anatomical gains: A retrospective analysis
Retina, ISSN: 15392864 0275004X
Rishi Singh; Tamara Lee; Linda Yau; Roman G. Rubio
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HAND2 targets define a network of transcriptional regulators that compartmentalize the early limb bud mesenchyme
Developmental Cell, ISSN: 18781551 15345807
Marco Osterwalder; Dario Speziale; Malak Shoukry; Rajiv Mohan; Robert Ivanek; Manuel Kohler; Christian Beisel; Xiaohui Wen; Suzie J. Scales; Vincent M. Christoffels; Axel Visel; Javier Lopez-Rios; Rolf Zeller
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Development of a robust RNA-based classifier to accurately determine ER, PR, and HER2 status in breast cancer clinical samples
Breast Cancer Research and Treatment, ISSN: 15737217 01676806
Wilson; Yuanyuan Xiao; Jill M. Spoerke; Jane Fridlyand; Koeppen; Eloisa Fuentes; Huw; Ilma Abbas; Arjan Gower; Erica Schleifman; Rupal Desai; Ling Fu; Teiko Sumiyoshi; Joyce A. O’Shaughnessy; Garret M. Hampton; Lackner
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Molecular mechanisms of Alzheimer disease protection by the A673T allele of amyloid precursor protein
Journal of Biological Chemistry, ISSN: 1083351X 00219258
Janice Maloney; Travis W. Bainbridge; Amy Gustafson; Shuo Zhang; Roxanne Kyauk; Pascal Steiner; Marcel P Van Der Brug; Yichin Liu; James A. Ernst; Ryan J. Watts; Jasvinder K. Atwal
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Therapeutic bispecific antibodies cross the blood-brain barrier in nonhuman primates
Science Translational Medicine, ISSN: 19466242 19466234
Y. Joy Yu; Jasvinder K. Atwal; Yin Zhang; Raymond K. Tong; Kristin R. Wildsmith; Christine Tan; Nga Bien-Ly; Maria Hersom; Janice Maloney; William J. Meilandt; Daniela Bumbaca; Kapil Gadkar; Kwame Hoyte; Wilman Luk; Yanmei Lu; James A. Ernst; Kimberly Scearce-Levie; Jessica A. Couch; Dennis; Ryan J. Watts
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Role of P-glycoprotein on the brain penetration and brain pharmacodynamic activity of the MEK inhibitor cobimetinib
Molecular Pharmaceutics, ISSN: 15438392 15438384
Edna F. Choo; Justin Ly; Jocelyn Chan; Sheerin Shahidi-Latham; Kirsten Messick; Emile G. Plise; Cristine Quiason; Lulu Yang
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Subcutaneous Tocilizumab Versus Placebo in Combination With Disease-Modifying Antirheumatic Drugs in Patients With Rheumatoid Arthritis
Arthritis Care and Research, ISSN: 21514658 2151464X
Alan Kivitz; Ewa Olech; Michael Borofsky; Beatriz M. Zazueta; Federico Navarro-Sarabia; Sebastião C. Radominski; Merrill; Lucy Rowell; Clare Nasmyth-Miller; Bao; Stephen Wright; Janet E. Pope
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Associations Between Preterm Birth, Low Birth Weight, andPostpartum Health in a Predominantly Hispanic WICPopulation
Journal of Nutrition Education and Behavior, ISSN: 14994046
Stephanie A. Leonard; Denise Gee; Yuda Zhu; Catherine M. Crespi; Shannon E. Whaley
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An antimesothelin-monomethyl auristatin E conjugate with potent antitumor activity in ovarian, pancreatic, and mesothelioma models
Molecular Cancer Therapeutics, ISSN: 15388514 15357163
Suzie J. Scales; Nidhi Gupta; Glenn Pacheco; Ron Firestein; French; Koeppen; Linda Rangell; Vivian Barry-Hamilton; Luis; Josefa Chuh; Yin Zhang; Gladys S. Ingle; Aimee Fourie-O'Donohue; Katherine R. Kozak; Ross; Dennis; Spencer
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A generic UHPLC-UV-MS method for cleaning verification of highly potent drugs
American Pharmaceutical Review, ISSN: 10998012
Syed Salman Lateef; Vinayak Ak; Michael W. Dong; Christine Gu
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It's time to regulate: Coping with product-induced nongenetic clonal instability in CHO cell lines via regulated protein expression
Biotechnology Progress, ISSN: 15206033 87567938
Shahram Misaghi; Chang; Snedecor
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Standardized extractables testing protocol for single-use systems in biomanufacturing
Pharmaceutical Engineering, ISSN: 02738139
Weibing Ding; Gary Madsen; Ekta Mahajan; Seamus O'Connor; Ken Wong
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VEGF modulates synaptic activity in the developing spinal cord
Developmental Neurobiology, ISSN: 1932846X 19328451
Sylvaine Guérit; Anne-Emilie Allain; Céline Léon; William Cazenave; Napoleone Ferrara; Pascal Branchereau; Andréas Bikfalvi
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Rituximab for the treatment of relapses in antineutrophil cytoplasmic antibody-associated vasculitis
Arthritis and Rheumatology, ISSN: 23265205 23265191
Miloslavsky; Specks; Merkel; Seo; Spiera; Langford; Hoffman; Cees Kallenberg; St.clair; Tchao; Viviano; Linna Ding; Iklé; Villarreal; Brett Jepson; Paul Brunetta; Allen; Fervenza; Duvuru Geetha; Keogh; Kissin; Monach; Peikert; Stegeman; Steven R. Ytterberg; John H. Stone
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Assessing stability-indicating methods for coelution by two-dimensional liquid chromatography with mass spectrometric detection
Journal of Separation Science, ISSN: 16159314 16159306
Venkatramani; James Girotti; Larry Wigman; Nicholas Chetwyn
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Treatment patterns and outcomes among patients with metastatic melanoma treated in community practice
International Journal of Dermatology, ISSN: 13654632 00119059
Mark S. Walker; Carolina Reyes; Jiandong Kerr; Sacha Satram-Hoang; Edward J. Stepanski
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Prevalence of and risk factors for diabetic macular edema in the United States
JAMA Ophthalmology, ISSN: 21686165
Rohit Varma; Neil M. Bressler; Quan V. Doan; Michelle Gleeson; Mark Danese; Julie K. Bower; Elizabeth Selvin; Chantal M. Dolan; Jennifer T. Fine; Shoshana Colman; Adam Turpcu
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Twenty-four-month efficacy and safety of 0.5 mg or 2.0 mg ranibizumab in patients with subfoveal neovascular age-related macular degeneration
Ophthalmology, ISSN: 15494713 01616420
Allen C. Ho; Brandon G. Busbee; Carl D. Regillo; Mark R. Wieland; Sherri A. Van Everen; Zhengrong Li; Roman G. Rubio; Phillip Lai
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Pharmacokinetics of ranibizumab after intravitreal administration in patients with retinal vein occlusion or diabetic macular edema
Ophthalmology, ISSN: 15494713 01616420
Yi Zhang; Zhenling Yao; Nitin Kaila; Peter Kuebler; Jennifer Visich; Mauricio Maia; Lisa Tuomi; Jason S. Ehrlich; Roman G. Rubio; Peter A. Campochiaro
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Characterizing monoclonal antibody structure by carbodiimide/GEE footprinting
mAbs, ISSN: 19420870 19420862
Parminder Kaur; Sara Tomechko; Janna Kiselar; Wuxian Shi; Galahad Deperalta; Aaron T. Wecksler; Giridharan Gokulrangan; Victor Ling; Mark R. Chance
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