Genentech: Publications

February 11, 2010

Chronic DLL4 blockade induces vascular neoplasms

Nature, ISSN: 00280836 14764687

Minhong Yan; Christopher Callahan; Joseph Beyer; Krishna P. Allamneni; Gu Zhang; John B.B. Ridgway; Kyle Niessen; Greg D. Plowman

View on Scopus

February 10, 2010

Fast and SNP-tolerant detection of complex variants and splicing in short reads

Bioinformatics, ISSN: 13674803 14602059

Thomas D Wu; Serban Nacu

View on Scopus

February 3, 2010

Benzo[a]pyrene increases the Nrf2 content by downregulating the Keap1 Message

Toxicological Sciences, ISSN: 10960929 10966080

Phuong Minh Nguyen; Miki Susanto Park; Marilynn Chow; Jae H. Chang; Lisa Wrischnik; William K. Chan

View on Scopus

February 1, 2010

Isoform-specific phosphoinositide 3-kinase inhibitors exert distinct effects in solid tumors

Cancer Research, ISSN: 00085472 15387445

Kyle A. Edgar; Jeffery J. Wallin; Megan Berry; Leslie Lee; Wei Wei Prior; Deepak Sampath; Lori S. Friedman; Marcia Belvin

View on Scopus

February 1, 2010

Association of methotrexate and tumour necrosis factor antagonists with risk of infectious outcomes including opportunistic infections in the CORRONA registry

Annals of the Rheumatic Diseases, ISSN: 00034967 14682060

Greenberg; Reed; Joel M. Kremer; Tindall; Arthur Kavanaugh; Zheng; Bishai; Hochberg

View on Scopus

February 1, 2010

Small-molecule pan-IAP antagonists: A patent review

Expert Opinion on Therapeutic Patents, ISSN: 13543776

Flygare; Wayne J. Fairbrother

View on Scopus

February 1, 2010

Active, but not passive cigarette smoking was inversely associated with mammographic density

Cancer Causes and Control, ISSN: 09575243 15737225

Lesley Butler; Ellen B. Gold; Shannon M. Conroy; Carolyn J. Crandall; Gail A. Greendale; Nina Oestreicher; Charles P. Quesenberry Jr.; Laurel A. Habel

View on Scopus

February 1, 2010

Baseline autoantibody profiles predict normalization of complement and anti-dsDNA autoantibody levels following Rituximab treatment in systemic lupus erythematosus

Lupus, ISSN: 09612033

Tew; Rabbee; Kristen Wolslegel; Hsin-Ju Hsieh; John G. Monroe; Timothy W. Behrens; Paul Brunetta; Mary E. Keir

View on Scopus

February 1, 2010

Pathways mediating VEGF-independent tumor angiogenesis

Cytokine and Growth Factor Reviews, ISSN: 13596101

Napoleone Ferrara

View on Scopus

February 1, 2010

BAK and BAX deletion using zinc-finger nucleases yields apoptosis-resistant CHO cells

Biotechnology and Bioengineering, ISSN: 00063592 10970290

Gregory J. Cost; Yevgeniy Freyvert; Annamaria Vafiadis; Yolanda Santiago; Jeffrey C. Miller; Edward J. Rebar; Trevor N. Collingwood; Andrew Snowden; Philip D. Gregory

View on Scopus

February 1, 2010

Targeting the tumor microenvironment with Src kinase inhibition

Clinical Cancer Research, ISSN: 10780432

Alicia S Chung; Napoleone Ferrara

View on Scopus

February 1, 2010

Molecular predictors of 3D morphogenesis by breast cancer cell lines in 3D culture

PLoS Computational Biology, ISSN: 1553734X 15537358

Ju Han; Hang Chang; Orsi Giricz; Genee Y. Lee; Frederick L. Baehner; Joe W. Gray; Mina J. Bissell; Paraic A. Kenny; Bahram Parvin

View on Scopus

February 1, 2010

Bioavailability in healthy adults of efavirenz capsule contents mixed with a small amount of food

American Journal of Health-System Pharmacy, ISSN: 15352900 10792082

Sanjeev Kaul; Ping Ji; Michael W. Lu; Kim L. Nguyen; Tong Shangguan; Dennis Grasela

View on Scopus

February 1, 2010

Modular architecture of Munc13/calmodulin complexes: Dual regulation by Ca 2 and possible function in short-term synaptic plasticity

EMBO Journal, ISSN: 02614189 14602075

Fernando Rodríguez-Castãeda; Mitcheell Maestre-Martínez; Nicolas Coudevylle; Kalina Dimova; Harald Junge; Noa Lipstein; Donghan Lee; Stefan Becker; Nils Brose; Olaf Jahn; Teresa Carlomagno; Christian Griesinger

View on Scopus

February 1, 2010

Editorial overview

Current Opinion in Immunology, ISSN: 09527915

Ira Mellman; Peter Cresswell

View on Scopus

February 1, 2010

Outlier options: Consider simple parametric tests to find an outlier's significance

Quality Progress, ISSN: 0033524X

Julia E. Seaman; I. Elaine Allen

View on Scopus

February 1, 2010

Ixabepilone: Providing new hope for women with breast cancer after anthracycline and taxane failure

Clinical journal of oncology nursing, ISSN: 10921095 1538067X

Alisha Stein

View on Scopus

January 29, 2010

Understanding and mitigating conductivity transitions in weak cation exchange chromatography

Journal of Chromatography A, ISSN: 00219673

Jace Fogle; Jenny Hsiung

View on Scopus

January 25, 2010

Dynamics of the bacterial intermediate filament crescentin in vitroand in vivo

PLoS ONE, ISSN: 19326203

Osigwe Esue; Laura Rupprecht; Sean X. Sun; Denis Wirtz

View on Scopus

January 22, 2010

Autocrine VEGF Signaling Synergizes with EGFR in Tumor Cells to Promote Epithelial Cancer Development

Cell, ISSN: 00928674

Beate M. Lichtenberger; Poi Kiang Tan; Heide Niederleithner; Napoleone Ferrara; Peter Petzelbauer; Maria Sibilia

View on Scopus

January 19, 2010

Local Protease Signaling Contributes to Neural Tube Closure in the Mouse Embryo

Developmental Cell, ISSN: 15345807

Eric Camerer; Adrian Barker; Daniel N. Duong; Rajkumar Ganesan; Hiroshi Kataoka; Ivo Cornelissen; Molly R. Darragh; Arif Hussain; Yao-Wu Zheng; Yoga Srinivasan; Christopher Brown; Shan-Mei Xu; Jean B. Regard; Chen-Yong Lin; Charles S. Craik; Daniel Kirchhofer; Shaun R. Coughlin

View on Scopus

January 19, 2010

Stromal cell-derived factor-1/CXCL12 contributes to MMTV-Wnt1 tumor growth involving Gr1+CD11b+ cells

PLoS ONE, ISSN: 19326203

Bob Y. Liu; Soloviev; Peter Chang; John Lee; Xiaodong Huang; Cuiling Zhong; Napoleone Ferrara; Paul G. Polakis; Sakanaka

View on Scopus

January 19, 2010

Utilization of lysozyme charge ladders to examine the effects of protein surface charge distribution on binding affinity in ion exchange systems

Langmuir, ISSN: 07437463

Wai Keen Chung; Steven T. Evans; Alexander S. Freed; James J. Keba; Zachary C. Baer; Kaushal Rege; Steven M. Cramer

View on Scopus

January 19, 2010

β1 Integrin Establishes Endothelial Cell Polarity and Arteriolar Lumen Formation via a Par3-Dependent Mechanism

Developmental Cell, ISSN: 15345807

Ann C. Zovein; Alfonso Luque; Kirsten A. Turlo; Jennifer J. Hofmann; Kathleen M. Yee; Michael S. Becker; Reinhard Fässler; Ira Mellman; Timothy F. Lane; M. Luisa Iruela-Arispe

View on Scopus

January 18, 2010

Negative regulation of autoimmune demyelination by the inhibitory receptor CLM-1

Journal of Experimental Medicine, ISSN: 00221007 15409538

Hongkang Xi; Kenneth J. Katschke Jr.; Karim Y. Helmy; Paige A. Wark; Noelyn Kljavin; Hilary F. Clark; Jeffrey Eastham-Anderson; Theresa Shek; Merone Roose-Girma; Nico Ghilardi; Menno Van Lookeren Campagne

View on Scopus

January 15, 2010

Corrigendum to "GDC-0449-A potent inhibitor of the hedgehog pathway" [Bioorg. Med. Chem. Lett. 19 (2009) 5576] (DOI:10.1016/j.bmcl.2009.08.049)

Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X

Kirk D. Robarge; Shirley A. Brunton; Georgette M. Castanedo; Yong Cui; Dina; Richard Goldsmith; Stephen Gould; Oivin Guichert; Janet Gunzner; Jason S Halladay; Wei Jia; S. Cyrus Khojasteh; Michael F. T. Koehler; Karen Kotkow; Hank La; Rebecca L. LaLonde; Kevin Lau; Leslie Lee; Derek Marshall; James C. Marsters Jr.; Lesley J. Murray; Changgeng Qian; Lee L. Rubin; Laurent Salphati; Mark S. Stanley; John H.A. Stibbard; Daniel P. Sutherlin; Savita Ubhayakar; Shumei Wang; Susan C. Wong; Minli Xie

View on Scopus

January 15, 2010

Reversing HOXA9 oncogene activation by PI3K inhibition: Epigenetic mechanism and prognostic significance in human glioblastoma

Cancer Research, ISSN: 00085472 15387445

Bruno M. Costa; Justin S. Smith; Ying Chen; Justin Chen; Phillips; Kenneth D. Aldape; Giuseppe Zardo; Janice M. Nigro; C. David James; Jane Fridlyand; Rui M. Reis; Joseph F. Costello

View on Scopus

January 15, 2010

Cutting edge: Plasmacytoid dendritic cells induce IL-10 production in T cells via the Delta-like-4/Notch axis

Journal of Immunology, ISSN: 00221767 15506606

Nadine Kassner; Manuela Krueger; Hideo Yagita; Andrzej Dzionek; Andreas Hutloff; Richard Kroczek; Alexander Scheffold; Sascha Rutz

View on Scopus

January 11, 2010

Neuropilin-2 mediates VEGF-C-induced lymphatic sprouting together with VEGFR3

Journal of Cell Biology, ISSN: 00219525 00219525

Yunling Xu; Li Yuan; Judy Mak; Luc Pardanaud; Maresa Caunt; Ian Kasman; Bruno Larrivee; Raquel del Toro; Steven Suchting; Alexander Medvinsky; Jillian Silva; Jian Yang; Jean-Léon Thomas; Alexander W. Koch; Kari Alitalo; Anne Eichmann; Anil Bagri

View on Scopus

January 8, 2010

Four-component synthesis of fully substituted 1,2,4-triazoles

Angewandte Chemie - International Edition, ISSN: 14337851

Steven T. Staben; Nicole Blaquiere

View on Scopus

January 8, 2010

Industrial case study: Evaluation of a mixed-mode resin for selective capture of a human growth factor recombinantly expressed in E. coli

Journal of Chromatography A, ISSN: 00219673

Kimberly A. Kaleas; Charles H. Schmelzer; Shelly A. Pizarro

View on Scopus

January 7, 2010

Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival

Nature, ISSN: 00280836 14764687

Martin Schwickart; Xiaodong Huang; Jennie R. Lill; Jinfeng Liu; Ron Ferrando; French; Heather Maecker; Karen M. O'Rourke; J.Fernando Bazan; Jeffrey Eastham-Anderson; Peng Yue; David Dornan; David C.S. Huang; Vishva M. Dixit

View on Scopus

January 1, 2010

Pharmaceutical medical information contact centers: Results of three benchmarking surveys

Drug Information Journal, ISSN: 00928615

Pete Guillot; Stacey M. Fung

View on Scopus

January 1, 2010

Semi-automated protein binding methodology using equilibrium dialysis and a novel mixed-matrix cassette approach

Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549

Emile G. Plise; Daniel Tran; Laurent Salphati

View on Scopus

January 1, 2010

Factors affecting the viscosity in high concentration solutions of different monoclonal antibodies

Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549

Sandeep Yadav; Steven J. Shire; Devendra S. Kalonia

View on Scopus

January 1, 2010

Standardizing rodent trimming and embedding guidelines for histology: Improving efficiency in the laboratory

Journal of Histotechnology, ISSN: 01478885

Monika Larson; Taylor; Marjie Van Hoy

View on Scopus

January 1, 2010

Surface expression of precursor N-cadherin promotes tumor cell invasion

Neoplasia (United States), ISSN: 14765586 15228002

Deborah Maret; Eugenia Gruzglin; Mohamad Seyed Sadr; Vincent Siu; Shan; Alexander W. Koch; Nabil G. Seidah; Rolando F. del Maestro; David R. Colman

View on Scopus

January 1, 2010

Molecular mechanisms of regulatory T cell development and suppressive function

Progress in Molecular Biology and Translational Science, ISSN: 18771173

Kim

View on Scopus

January 1, 2010

Cell biology redux.

Molecular Biology of the Cell, ISSN: 19394586

Ira Mellman

View on Scopus

January 1, 2010

Molecular biomarker analyses using circulating tumor cells

PLoS ONE, ISSN: 19326203

Elizabeth A. Punnoose; Siminder Atwal; Jill M. Spoerke; Heidi Savage; Ajay Pandita; Ru-Fang Yeh; Andrea Pirzkall; Bernard M. Fine; Lukas Amler; Daniel S. Chen; Lackner

View on Scopus

January 1, 2010

Questions about coverage accompany new fully implantable hearing system

Managed Care, ISSN: 10623388

Thomas Morrow

View on Scopus

January 1, 2010

On the possibility of self-induction of drug protein binding

Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549

Leonid M. Berezhkovskiy

View on Scopus

January 1, 2010

Randomized, double-masked, sham-controlled trial of ranibizumab for neovascular age-related macular degeneration: PIER study year 2

American Journal of Ophthalmology, ISSN: 00029394

Prema Abraham; Huibin Yue; Laura J. Wilson

View on Scopus

January 1, 2010

Structure of the Complex between HER2 and an Antibody Paratope Formed by Side Chains from Tryptophan and Serine

Journal of Molecular Biology, ISSN: 00222836

Robert D. Fisher; Ultsch; Andreas Lingel; Gabriele Schaefer; Lily Shao; Sara Birtalan; Sachdev S. Sidhu; Eigenbrot

View on Scopus

January 1, 2010

Effect of temperature, pH, dissolved oxygen, and hydrolysate on the formation of triple light chain antibodies in cell culture.

Biotechnology Progress, ISSN: 15206033

Natalia Gomez; Jun Ouyang; Mary D. H. Nguyen; Abigail R Vinson; Andy Lin; Inn H. Yuk

View on Scopus

January 1, 2010

Monoclonal antibody purification using cationic polyelectrolytes: an alternative to column chromatography.

Biotechnology Progress, ISSN: 15206033

Thanmaya Peram; Paul McDonald; Jayme N. Carter-Franklin; Fahrner

View on Scopus

January 1, 2010

Treatment outcomes by tumor histology in eastern cooperative group study E4599 of bevacizumab with paclitaxel/carboplatin for advanced non-small cell lung cancer

Journal of Thoracic Oncology, ISSN: 15561380 15560864

Alan Sandler; Jing Yi; Suzanne Dahlberg; Margaret M. Kolb; Lisa I. Wang; Julie Hambleton; Joan H. Schiller; David H. Johnson

View on Scopus

January 1, 2010

Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency

Nature Genetics, ISSN: 15461718 10614036

Ricardo C. Ferreira; Qiang Pan-Hammarström; Robert R. Graham; Vesela Gateva; Gumersindo Fontán; Annette T. Lee; Ward Ortmann; Elena Urcelay; Miguel Fernández-Arquero; Concepción Núñez; Gudmundur Jorgensen; Björn R. Ludviksson; Sinikka Koskinen; Katri Haimila; Hilary F. Clark; Lars Klareskog; Peter K. Gregersen; Timothy W. Behrens; Lennart Hammarström

View on Scopus

January 1, 2010

Anti-CD22-MCC-DM1: An antibody-drug conjugate with a stable linker for the treatment of non-Hodgkin's lymphoma

Leukemia, ISSN: 14765551 08876924

Andrew G. Polson; Marna Williams; Gray; Reina N. Fuji; Kirsten Achilles Poon; Jacqueline McBride; Helga Raab; Thomas Januario; MaryAnn Go; Jeffrey Lau; Shang-Fan Yu; Du; Franklin Fuh; Christine Tan; Yan Wu; Wei-Ching Liang; Saileta Prabhu; Jean-Philippe Stephan; Hongo; Randall Dere; Rong Deng; Cullen; Ruth De Tute; Bennett; Andy Rawstron; Andrew S. Jack; Allen Ebens

View on Scopus

January 1, 2010

Characterization of a nutrient feed precipitate from an E. coli fermentation process.

Biotechnology Progress, ISSN: 15206033

Lauren Speciner; Erin Mallon; Susan Leung; Mike Laird; Osigwe Esue

View on Scopus

Attention: This page may not render properly. The browser you are using, Internet Explorer 10, is no longer supported.

Publications

Join Our Team

Two Scientists Walk Into a Bar