Scientists / Publications

Publications

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DISPLAYING 9401 - 9450 OF 15578 RESULTS

Preclinical evaluation of carcinoembryonic cell adhesion molecule (CEACAM) 6 as potential therapy target for pancreatic adenocarcinoma
Journal of Pathology, ISSN: 00223417 10969896
Laura A. Strickland; Ross; Simon P. Williams; Ross; Maria Romero; Spencer; Erickson; Julie Sutcliffe; Caroline Verbeke; Paul G. Polakis; Nicholas Van Bruggen; Koeppen
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Dlx1&2 and Mash1 transcription factors control MGE and CGE patterning and differentiation through parallel and overlapping pathways
Cerebral Cortex, ISSN: 10473211 14602199
Jason E. Long; Inma Cobos; Gregory B. Potter; John L. R. Rubenstein
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Differential roles of Netrin-1 and its receptor DCC in inferior olivary neuron migration
Molecular and Cellular Neuroscience, ISSN: 10447431
Séverine Marcos; Stéphanie Backer; Frédéric Causeret; Marc Tessier-Lavigne; Evelyne Bloch-Gallego
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Deconvolution of blood microarray data identifies cellular activation patterns in systemic lupus erythematosus
PLoS ONE, ISSN: 19326203
Abbas Alexander; Kristen Wolslegel; Dhaya Seshasayee; Zora Modrusan; Hilary F. Clark
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Second International Conference on Accelerating Biopharmaceutical Development March 9-12, 2009, Coronado, CA, USA
Biotechnology Progress, ISSN: 87567938
Janice M. Reichert; Nitya M. Jacob; Ashraf Amanullah
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MBX-102/JNJ39659100, a novel peroxisome proliferator-activated receptor-ligand with weak transactivation activity retains antidiabetic properties in the absence of weight gain and edema
Molecular Endocrinology, ISSN: 08888809
Francine M. Gregoire; Fang Zhang; Holly J. Clarke; Thomas A. Gustafson; Dorothy D. Sears; Svetlana Favelyukis; James Lenhard; Dennis Rentzeperis; L. Edward Clemens; Yi Mu; Brian E. Lavan
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Development of prophylactic and therapeutic vaccines using the ISCOMATRIX adjuvant
Immunology and Cell Biology, ISSN: 08189641 14401711
Eugene Maraskovsky; Max Schnurr; Nicholas S. Wilson; Neil C Robson; Jeff Boyle; Debbie Drane
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Removal of endogenous retrovirus-like particles from CHO-cell derived products using Q sepharose fast flow chromatography
Biotechnology Progress, ISSN: 87567938
Daniel M. Strauss; Scott Lute; Kurt Brorson; Gregory S. Blank; Qi Chen; Bin Yang
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The structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signaling
Nature Structural and Molecular Biology, ISSN: 15459993 15459985
Ivan Bosanac; Henry R. Maun; Suzie J. Scales; Xiaohui Wen; Andreas Lingel; J.Fernando Bazan; Frederic J. De Sauvage; Sarah G. Hymowitz; Lazarus
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Homeless women's personal networks: Implications for understanding risk behavior
Human Organization, ISSN: 00187259
Joan Tucker; David Kennedy; Gery Ryan; Suzanne Wenzel; Daniela Golinelli; James L. Zazzali
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Technology comparisons for anti-therapeutic antibody and neutralizing antibody assays in the context of an anti-TNF pharmacokinetic study
Journal of Immunological Methods, ISSN: 00221759
Kelly M. Loyet; Rong Deng; Wei-Ching Liang; Yan Wu; Henry B. Lowman; Laura DeForge
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Expression and activity of the efflux transporters ABCB1, ABCC2 and ABCG2 in the human colorectal carcinoma cell line LS513
European Journal of Pharmaceutical Sciences, ISSN: 09280987
Laurent Salphati; Emile G. Plise; Guangmin Li
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Novel therapeutic targets along the Th17 pathway
European Journal of Immunology, ISSN: 00142980 15214141
Wenjun Ouyang; Ellen H. Filvaroff; Yan Hu; Jane L. Grogan
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Development of novel drugs targeting inhibitors of apoptosis
Future Oncology, ISSN: 14796694 17448301
Flygare; Domagoj Vucic
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Finding and achieving value in cancer care
JNCCN Journal of the National Comprehensive Cancer Network, ISSN: 15401405 15401413
Clifford Goodman; Joseph S. Bailes; Stephen B. Edge; A. Mark Fendrick; Scott Gottlieb; Robert Mass; Lee N. Newcomer; Lynn Zonakis
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Toward an effective targeted chemotherapy for multiple myeloma
Clinical Cancer Research, ISSN: 10780432
Andrew G. Polson; Mark X. Sliwkowski
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Multi-round virus filter integrity test sensitivity
Biotechnology and Bioengineering, ISSN: 00063592 10970290
Chris Dowd
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Suppression of HER2/HER3-mediated growth of breast cancer cells with combinations of GDC-0941 PI3K inhibitor, trastuzumab, and pertuzumab
Clinical Cancer Research, ISSN: 10780432
Evelyn Yao; Wei Zhou; Si Tuen Lee-Hoeflich; Tom Truong; Matthias Peter; Jeffrey Eastham-Anderson; Nicholas Lewin-Koh; Bert Gunter; Marcia Belvin; Lesley J. Murray; Lori S. Friedman; Mark X. Sliwkowski; Klaus P. Hoeflich
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Engineering human IgG1 affinity to human neonatal Fc receptor: Impact of affinity improvement on pharmacokinetics in primates
Journal of Immunology, ISSN: 00221767 15506606
Yik Andy Yeung; Maya Leabman; Jonathan S. Marvin; Julia Qiu; Adams; Samantha Lien; Melissa A. Starovasnik; Henry B. Lowman
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Interaction of IF2 with the ribosomal GTPase-associated center during 70S initiation complex formation
Biochemistry, ISSN: 00062960
Haiou Qin; Christina Grigoriadou; Barry S. Cooperman
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Targeting interferon alpha subtypes in serum: A comparison of analytical approaches to the detection and quantitation of proteins in complex biological matrices
Journal of Proteome Research, ISSN: 15353893
Anita Izrael-Tomasevic; Lilian Phu; Qui Phung; Jennie R. Lill; David Arnott
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Slow binding inhibition and mechanism of resistance of non-nucleoside polymerase inhibitors of Hepatitis C virus
Journal of Biological Chemistry, ISSN: 00219258 1083351X
Julie Qi Hang; Yanli Yang; Seth F. Harris; Vincent J.P. Leveque; Hannah J. Whittington; Sonal Rajyaguru; Gloria Ao-Leong; Matthew F. McCown; April Wong; Anthony M. Giannetti; Sophie Le Pogam; Francisco Talamás; Nick Cammack; Nájera; Klumpp
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Hedgehog Signaling Is Dispensable for Adult Murine Hematopoietic Stem Cell Function and Hematopoiesis
Cell Stem Cell, ISSN: 19345909
Inga Hofmann; Elizabeth H. Stover; Dana E. Cullen; Junhao Mao; Kelly J. Morgan; Benjamin H. Lee; Michael G. Kharas; Peter G. Miller; Melanie G. Cornejo; Rachel Okabe; Scott A. Armstrong; Nico Ghilardi; Stephen Gould; Frederic J. De Sauvage; Andrew P. McMahon; D. Gary Gilliland
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Axotomy-induced smad1 activation promotes axonal growth in adult sensory neurons
Journal of Neuroscience, ISSN: 02706474 15292401
Hongyan Zou; Carole Ho; Karen G. Wong; Marc Tessier-Lavigne
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Characterization of multiple stable conformers of the EC5 domain of E-cadherin and the interaction of EC5 with E-cadherin peptides
Chemical Biology and Drug Design, ISSN: 17470277
Kai Zheng; Jennifer S. Laurence; Krzysztof Kuczera; Gennady Verkhivker; C. Russell Middaugh; Teruna J. Siahaan
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Non-invasive monitoring provides fast payback
Chemical Processing, ISSN: 00092630
Chris Stubbs
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PET of glial metabolism using 2-18F-fluoroacetate
Journal of Nuclear Medicine, ISSN: 01615505
Jan Marik; Annie Ogasawara; Baby Martin-McNulty; Ross; Judith E. Flores; Herman S. Gill; Jeff N. Tinianow; Alexander N. Vanderbilt; Merry C. Nishimura; Franklin V. Peale Jr.; Cinthia V Pastuskovas; Joan M. Greve; Nicholas Van Bruggen; Simon P. Williams
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Phase I study of the effect of gastric acid pH modulators on the bioavailability of oral dasatinib in healthy subjects
Journal of Clinical Pharmacology, ISSN: 00912700 15524604
Timothy Eley; Feng R. Luo; Shruti Agrawal; Ashish Sanil; James Manning; Tong Li; Anne Blackwood-Chirchir; Richard Bertz
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Assessment of a sixteen-week training program on strength, pain, and function in rheumatoid arthritis patients
Journal of Clinical Rheumatology, ISSN: 10761608
Hilary G. Flint-Wagner; Jeffrey Lisse; Timothy G. Lohman; Scott B. Going; Terri Guido; Ellen Cussler; Donald Gates; David E. Yocum
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Review of recent genome-wide association scans in lupus
Journal of Internal Medicine, ISSN: 09546820 13652796
Robert R. Graham; Geoffrey Hom; Ward Ortmann; Timothy W. Behrens
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Analysis of charge heterogeneities in mAbs using imaged CE
Electrophoresis, ISSN: 01730835 15222683
Xiaoping Z. He; Amy H. Que; Jim J. Mo
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Evaluation of multiple in vitro systems for assessment of CYP3A4 induction in drug discovery: Human hepatocytes, pregnane X receptor reporter gene, and Fa2N-4 and HepaRG Cells
Drug Metabolism and Disposition, ISSN: 00909556 1521009X
Dermot F. McGinnity; George Zhang; Jane R. Kenny; Geraldine A. Hamilton; Sara Otmani; Karen R. Stams; Suzzette Haney; Patrick Brassil; David M Stresser; Robert J. Riley
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Mechanisms of Hedgehog pathway activation in cancer and implications for therapy
Trends in Pharmacological Sciences, ISSN: 01656147
Suzie J. Scales; Frederic J. De Sauvage
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An analytical system for the characterization of highly heterogeneous mixtures of N-linked oligosaccharides
Analytical Biochemistry, ISSN: 10960309 00032697
Briggs; Rodney Keck; Stacey Ma; Wendy Lau; Andrew J.S. Jones
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A class of 2,4-bisanilinopyrimidine Aurora A inhibitors with unusually high selectivity against Aurora B
Journal of Medicinal Chemistry, ISSN: 00222623
Ignacio Aliagas; Burdick; Laura B. Corson; Jennafer Dotson; Jason H. Drummond; Carter Fields; Oscar W Huang; Thomas Hunsaker; Tracy L. Kleinheinz; Elaine B. Krueger; Jun Liang; John Moffat; Gail L. Phillips; Rebecca Pulk; Thomas E. Rawson; Ultsch; Leslie Walker; Wiesmann; Birong Zhang; Bing-Yan Zhu; Andrea G Cochran
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Combined targeting of BRAF and CRAF or BRAF and PI3K effector pathways is required for efficacy in NRAS mutant tumors
PLoS ONE, ISSN: 19326203
Bijay S. Jaiswal; Vasantharajan Janakiraman; Noelyn Kljavin; Jeffrey Eastham-Anderson; James Cupp; Yuxin Liang; David P. Davis; Klaus P. Hoeflich; Somasekar Seshagiri
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Primary Sjögren's Syndrome: Health experiences and predictors of health quality among patients in the United States
Health and Quality of Life Outcomes, ISSN: 14777525
Barbara Segal; Simon J. Bowman; Philip C. Fox; Frederick B. Vivino; Nandita Murukutla; Jeff Brodscholl; Sarika Ogale; Lachy McLean
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MBX-102/JNJ39659100, a novel non-TZD selective partial PPAR-γ agonist lowers triglyceride independently of PPAR-α activation
PPAR Research, ISSN: 16874757 16874765
Francine M. Gregoire; Apurva Chandalia; Holly J. Clarke; L. Edward Clemens; Bindu Pandey; Vic Vicena; Paul Lee; Brian E. Lavan
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ATP-citrate lyase links cellular metabolism to histone acetylation
Science, ISSN: 00368075 10959203
Kathryn E. Wellen; Georgia Hatzivassiliou; Uma M. Sachdeva; Thi V. Bui; Justin R. Cross; Craig B. Thompson
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Development of a rapid sanitization solution for silica-based protein A affinity adsorbents
Journal of Chromatography A, ISSN: 00219673
Marc Rogers; Hiraoka-Sutow; Polly Mak; Fred Mann; Lebreton
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Effect of EDTA and methionine on preventing loss of viscosity of cellulose-based topical gel
AAPS PharmSciTech, ISSN: 15309932
Junyan A. Ji; Erika Ingham; John Wang
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Ubiquilins accelerate autophagosome maturation and promote cell survival during nutrient starvation
Autophagy, ISSN: 15548635 15548627
Elsa N. N'Diaye; Jayanta Debnath; Eric J. Brown
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Ion exchange chromatography of monoclonal antibodies: Effect of resin ligand density on dynamic binding capacity
Journal of Chromatography A, ISSN: 00219673
Ann Marie Hardin; Chithkala Harinarayan; Gunnar Malmquist; Andreas Axén; Robert Van Reis
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Surface extenders and an optimal pore size promote high dynamic binding capacities of antibodies on cation exchange resins
Journal of Chromatography A, ISSN: 00219673
David S. Hart; Chithkala Harinarayan; Gunnar Malmquist; Andreas Axén; Mandakini Sharma; Robert Van Reis
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Cullin3-Based Polyubiquitination and p62-Dependent Aggregation of Caspase-8 Mediate Extrinsic Apoptosis Signaling
Cell, ISSN: 00928674
Zhaoyu Jin; Yun Li; Pitti; David Lawrence; Victoria Pham; Jennie R. Lill; Avi Ashkenazi
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Erratum: Erythropoietin dosing in children with chronic kidney disease: Based on body size or on hemoglobin deficit? (Pediatric Nephrology (2009) 10.1007/s00467-008-0955-2)
Pediatric Nephrology, ISSN: 0931041X
Ruediger E. Port; Otto Mehls
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Characterization of deamidated peptide variants by micro-preparative capillary electrophoresis and mass spectrometry
Journal of Chromatography A, ISSN: 00219673
Lynn Gennaro; Oscar Salas-Solano
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A therapeutic antibody and its antigen form different complexes in serum than in phosphate-buffered saline: A study by analytical ultracentrifugation
Analytical Biochemistry, ISSN: 10960309 00032697
Barthélemy Demeule; Steven J. Shire; Jun Liu
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A developmentally regulated Myb domain protein regulates expression of a subset of stage-specific genes in Entamoeba histolytica
Cellular Microbiology, ISSN: 14625814 14625822
Gretchen M. Ehrenkaufer; Jason A. Hackney; Upinder Singh
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A nanocube plasmonic sensor for molecular binding on membrane surfaces
Nano Letters, ISSN: 15306984
William J. Galush; Sarah A. Shelby; Martin J. Mulvihill; Andrea Tao; Peidong Yang; Jay T. Groves
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