Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 9551 - 9600 OF 15578 RESULTS

Curcumin inhibits the activity of ABCG2/BCRP1, a multidrug resistance-linked ABC drug transporter in mice
Pharmaceutical Research, ISSN: 07248741 1573904X
Suneet Shukla; Hani Zaher; Anika Hartz; Björn Bauer; Joseph A. Ware; Suresh V. Ambudkar
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Role of benzyl alcohol in the prevention of heat-induced aggregation and inactivation of hen egg white lysozyme
European Journal of Pharmaceutics and Biopharmaceutics, ISSN: 09396411
Monu Kumari Goyal; Ipsita Roy; Uttam Chand Banerjee; Vikas Sharma; Arvind Kumar Bansal
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Atrophins' emerging roles in development and neurodegenerative disease
Cellular and Molecular Life Sciences, ISSN: 1420682X 15691632
Yiguo Shen; Andrew S. Peterson
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Essential and unique roles of PIP5K-γ and - α in Fcγ receptor-mediated phagocytosis
Journal of Cell Biology, ISSN: 15408140 00219525
Yuntao S. Mao; Masaki Yamaga; Xiaohui Zhu; Yongjie Wei; Hui-Qiao Sun; Jing Wang; Mia Yun; Yanfeng Wang; Gilbert Di Paolo; Michael J. Bennett; Ira Mellman; Charles S. Abrams; Pietro De Camilli; Christopher Y. Lu; Helen L. Yin
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Essential and unique roles of PIP5K-γ and - α in Fcγ receptor-mediated phagocytosis
Journal of Cell Biology, ISSN: 15408140 00219525
Yuntao S. Mao; Masaki Yamaga; Xiaohui Zhu; Yongjie Wei; Hui-Qiao Sun; Jing Wang; Mia Yun; Yanfeng Wang; Gilbert Di Paolo; Michael J. Bennett; Ira Mellman; Charles S. Abrams; Pietro De Camilli; Simon Craddock Lee; Helen L. Yin
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GPS navigation of the protein-stability landscape
Nature Biotechnology, ISSN: 10870156 15461696
Donald S. Kirkpatrick; Vishva M. Dixit
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A three-dimensional view of the molecular machinery of RNA interference
Nature, ISSN: 00280836 14764687
Martin Jinek; Jennifer A. Doudna
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In situ precipitation and vacuum drying of interferon alpha-2a: Development of a single-step process for obtaining dry, stable protein formulation
International Journal of Pharmaceutics, ISSN: 03785173
Vineet Kumar; Vikas Sharma; Devendra S. Kalonia
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Effect of polyols on polyethylene glycol (PEG)-induced precipitation of proteins: Impact on solubility, stability and conformation
International Journal of Pharmaceutics, ISSN: 03785173
Vineet Kumar; Vikas Sharma; Devendra S. Kalonia
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PLIC proteins or ubiquilins regulate autophagy-dependent cell survival during nutrient starvation
EMBO Reports, ISSN: 1469221X 14693178
Elsa N. N'Diaye; Kimberly K. Kajihara; Ivy Hsieh; J. Hiroshi Morisaki; Jayanta Debnath; Eric J. Brown
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Fatal Hepatitis Mediated by Tumor Necrosis Factor TNFα Requires Caspase-8 and Involves the BH3-Only Proteins Bid and Bim
Immunity, ISSN: 10747613
Kaufmann; Philipp J. Jost; Marc Pellegrini; Puthalakath; Gugasyan; Gerondakis; Erika Cretney; Mark J. Smyth; John Silke; Razq Hakem; Philippe Bouillet; Tak W. Mak; Vishva M. Dixit; Andreas Strasser
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Re-estimating the sample size of an on-going blinded trial based on the method of randomization block sums
Statistics in Medicine, ISSN: 02776715 10970258
Jitendra Ganju; Biao Xing
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By the scientists, for the scientists
Journal of Cell Biology, ISSN: 00219525 00219525
Ira Mellman
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Addition of bevacizumab to fluorouracil-based first-line treatment of metastatic colorectal cancer: Pooled analysis of cohorts of older patients from two randomized clinical trials
Journal of Clinical Oncology, ISSN: 0732183X
Fairooz F. Kabbinavar; Herbert Hurwitz; Jing Yi; Somnath Sarkar; Oliver Rosen
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Noncompetitive Inhibition of Hepatocyte Growth Factor-dependent Met Signaling by a Phage-derived Peptide
Journal of Molecular Biology, ISSN: 00222836
Eric Tam; Steven T. Runyon; Santell; Quan; Xiaoyi Yao; Daniel Kirchhofer; Nicholas J. Skelton; Lazarus
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PDGF-C Mediates the Angiogenic and Tumorigenic Properties of Fibroblasts Associated with Tumors Refractory to Anti-VEGF Treatment
Cancer Cell, ISSN: 15356108
Yongping Crawford; Ian Kasman; Lanlan Yu; Cuiling Zhong; Xiumin Wu; Zora Modrusan; Joshua S. Kaminker; Napoleone Ferrara
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The serine protease marapsin is expressed in stratified squamous epithelia and is up-regulated in the hyperproliferative epidermis of psoriasis and regenerating wounds
Journal of Biological Chemistry, ISSN: 00219258 1083351X
Wei Li; Dimitry Danilenko; Bunting; Rajkumar Ganesan; Susan Sa Ronald Ferrando; Thomas D Wu; Ganesh Kolumam; Wenjun Ouyang; Daniel Kirchhofer
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Prediction of the possibility of the secondary peaks of iv bolus drug plasma concentration time curve by the model that directly takes into account the transit time through the organ
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Leonid M. Berezhkovskiy
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Consistently very poorly controlled asthma, as defined by the impairment domain of the Expert Panel Report 3 guidelines, increases risk for future severe asthma exacerbations in The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) study
Journal of Allergy and Clinical Immunology, ISSN: 00916749
Tmirah Haselkorn; James E. Fish; Robert S. Zeiger; Stanley J. Szefler; Dave P. Miller; Bradley E. Chipps; F. Estelle R. Simons; Weiss; Sally E. Wenzel; Larry Borish; Eugene R. Bleecker
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Design and construction of synthetic phage-displayed Fab libraries.
Methods in Molecular Biology, ISSN: 10643745
Jenny Bostrom; Fuh
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Orphan disease gains second treatment option
Managed Care, ISSN: 10623388
Thomas Morrow
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Expanded availability of isotope boon to neuroblastoma diagnosis
Managed Care, ISSN: 10623388
Thomas Morrow
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Transgenic goats are key to antithrombin production
Managed Care, ISSN: 10623388
Thomas Morrow
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Sensitivity of administrative claims to identify incident cases of lung cancer: A comparison of 3 health plans
Journal of Managed Care Pharmacy, ISSN: 10834087
Scott D. Ramsey; John F. Scoggins; David Blough; Cara L. McDermott; Carolina Reyes
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A stepwise increase in recombinant human growth hormone dosing during puberty achieves improved pubertal growth: A national cooperative growth study report
Journal of Pediatric Endocrinology and Metabolism, ISSN: 0334018X
Linda Riddick; Craig Alter; Daniel Aaron Davis; James W. Frane; Barbara M. Lippe; Bert Bakker
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Viscoelastic characterization of high concentration antibody formulations using quartz crystal microbalance with dissipation monitoring
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Ankit Patel; Bruce A. Kerwin; Sekhar R. Kanapuram
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Baseline characteristics of patients enrolled in EXCELS: A cohort study
Annals of Allergy, Asthma and Immunology, ISSN: 15344436 10811206
Aidan Long; James E. Fish; Abdelkader Rahmaoui; Mary K. Miller; Mary S. Bradley; Hassan N. Taki; Anthony N. Demeo; Stephen A. Tilles; Stanley J. Szefler
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Root UV-B sensitive2 acts with root UV-B sensitive1 in a root ultraviolet B-sensing pathway
Plant Physiology, ISSN: 15322548 00320889
Colin D. Leasure; Hongyun Tong; Gigi Yuen; Xuewen Hou; Xuefeng Sun; Zheng-Hui He
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Prasugrel, new platelet inhibitor, subject of formulary debates.
Managed Care, ISSN: 10623388
Thomas Morrow
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Assessing medical information needs via an internet-based survey
Drug Information Journal, ISSN: 00928615
Stacey M. Fung; Laura Merriman; Maureen Cawley
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Identification of circulating neuropilin-1 and dose-dependent elevation following anti-neuropilin-1 antibody administration
mAbs, ISSN: 19420862
Yanmei Lu; Hong Xiang; Peter S. Liu; Raymond K. Tong; Ryan J. Watts; Alexander W. Koch; Wendy N. Sandoval; Lisa A. Damico; Lee Wong Wai; Meng
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The fate of free radicals in a cellulose based hydrogel: Detection by electron paramagnetic resonance spectroscopy
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Lipika Basumallick; Junyan A. Ji; Nariman Naber; Y. John Wang
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A tumor sorting protocol that enables enrichment of pancreatic adenocarcinoma cells and facilitation of genetic analyses
Journal of Molecular Diagnostics, ISSN: 15251578
Zachary Boyd; Rajiv Raja; Stephanie Johnson; Eberhard; Lackner
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Growth response, near-adult height, and patterns of growth and puberty in patients with Noonan syndrome treated with growth hormone
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X 0021972X
Alicia A. Romano; Ken Dana; Bert Bakker; Daniel Aaron Davis; Joanne Julius Hunold; Joan R. Jacobs; Barbara M. Lippe
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Using empirical phase diagrams to understand the role of intramolecular dynamics in immunoglobulin G stability
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Joshua D. Ramsey; Michelle L. Gill; Tim J. Kamerzell; E. Shane Price; Sangeeta B. Joshi; Steven M. Bishop; Cynthia N. Oliver; C. Russell Middaugh
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Absence of neuromyelitis optica igg antibody in an active relapsing-remitting multiple sclerosis population
Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, ISSN: 15365166 10708022
Craig H. Smith; Waubant; Annette Langer-Gould
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On the prediction of hepatic clearance using the diluted plasma in metabolic stability assay
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Leonid M. Berezhkovskiy; S. Cyrus Khojasteh; Jason S Halladay; Cornelis E. Hop
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Relative weight at ages 10 and 16 years and risk of endometriosis: A case-control analysis
Human Reproduction, ISSN: 14602350 02681161
Christina M. Nagle; Tanya A. Bell; David M. Purdie; Susan A. Treloar; Olsen; Grover; Adèle C. Green
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Predicting asthma control using patient attitudes toward medical care: The REACT score
Annals of Allergy, Asthma and Immunology, ISSN: 15344436 10811206
Craig A. Jones; Bruce G. Bender; Tmirah Haselkorn; James E. Fish; David R. Mink; Stephen P. Peters; Weiss
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Improving antibody binding affinity and specificity for therapeutic development.
Methods in Molecular Biology, ISSN: 10643745
Jenny Bostrom; Chingwei V. Lee; Lauric Haber; Fuh
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Determination of mean residence time of drug in plasma and the influence of the initial drug elimination and distribution on the calculation of pharmacokinetic parameters
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Leonid M. Berezhkovskiy
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Compatibility of a protein topical gel with wound dressings
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Junyan A. Ji; Oleg V. Borisov; Erika Ingham; Victor Ling; Y. John Wang
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Applying the CONSORT and STROBE Statements to Evaluate the Reporting Quality of Neovascular Age-related Macular Degeneration Studies
Ophthalmology, ISSN: 01616420
Anne E. Fung; Ram Palanki; Sophie J. Bakri; Eric E. Depperschmidt; Andrea Gibson
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Consideration of the linear concentration increase of the unbound drug fraction in plasma
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Leonid M. Berezhkovskiy
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Anion exchange chromatography provides a robust, predictable process to ensure viral safety of biotechnology products
Biotechnology and Bioengineering, ISSN: 00063592 10970290
Daniel M. Strauss; Gorrell; Magdalena Plancarte; Gregory S. Blank; Qi Chen; Bin Yang
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Slow growth induces heat-shock resistance in normal and respiratory-deficient yeast
Molecular Biology of the Cell, ISSN: 10591524
Charles Lu; Matthew J. Brauer; David Botstein
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Ubiquitin binding modulates IAP antagonist-stimulated proteasomal degradation of c-IAP1 and c-IAP21
Biochemical Journal, ISSN: 02646021 14708728
John W. Blankenship; Eugene Varfolomeev; Tatiana Goncharov; Anna V. Fedorova; Donald S. Kirkpatrick; Anita Izrael-Tomasevic; Lilian Phu; David Arnott; Mariam Aghajan; Zobel; J.Fernando Bazan; Wayne J. Fairbrother; Deshayes; Domagoj Vucic
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Coordinated concentration changes of transcripts and metabolites in Saccharomyces cerevisiae
PLoS Computational Biology, ISSN: 1553734X 15537358
Patrick H. Bradley; Matthew J. Brauer; Joshua D. Rabinowitz; Olga G. Troyanskaya
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Sparse combinatorial inference with an application in cancer biology
Bioinformatics, ISSN: 13674803 14602059
Sach Mukherjee; Steven Pelech; Richard M. Neve; Wen-Lin Kuo; Safiyyah Ziyad; Paul T. Spellman; Joe W. Gray; Terence P. Speed
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Twenty-four well plate miniature bioreactor system as a scale-down model for cell culture process development
Biotechnology and Bioengineering, ISSN: 00063592 10970290
Aaron Chen; Rajesh Chitta; David Chang; Ashraf Amanullah
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