Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 9801 - 9850 OF 15578 RESULTS

Dual-specificity phosphatases in the hypo-osmotic stress response of keratin-defective epithelial cell lines
Experimental Cell Research, ISSN: 00144827
Mirjana Liovic; Brian B. Lee; Marjana Tomic-Canic; Mariella D'Alessandro; Viacheslav N. Bolshakov; E. Birgitte Lane
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Dual-specificity phosphatases in the hypo-osmotic stress response of keratin-defective epithelial cell lines
Experimental Cell Research, ISSN: 00144827
Mirjana Liovic; Brian Lee; Marjana Tomic-Canic; Mariella D'Alessandro; Viacheslav N. Bolshakov; E. Birgitte Lane
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A NOD2-NALP1 complex mediates caspase-1-dependent IL-1β secretion in response to Bacillus anthracis infection and muramyl dipeptide
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424 10916490
Li-Chung Hsu; Syed R. Ali; Shauna McGillivray; Ping-Hui Tseng; Sanjeev Mariathasan; Eric W. Humke; Lars Eckmann; Jonathan J. Powell; Victor Nizet; Vishva M. Dixit; Michael Karin
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To kill a tumor cell: The potential of proapoptotic receptor agonists
Journal of Clinical Investigation, ISSN: 00219738 15588238
Avi Ashkenazi; Roy S. Herbst
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PCSK9 function and physiology
Journal of Lipid Research, ISSN: 00222275 15397262
Andrew S. Peterson; Loren G. Fong; Stephen G. Young
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A golden era of opportunity in immunotherapy discovery and development
Immunological Reviews, ISSN: 01052896 1600065X
Andrew A. Chan
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Vascular endothelial growth factors in pulmonary edema: An update
Journal of Thrombosis and Thrombolysis, ISSN: 09295305
Ioanna Kosmidou; Dimitrios Karmpaliotis; Ajay J. Kirtane; Hal V. Barron; C.Michael Gibson
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Design opportunities for actively targeted nanoparticle vaccines
Nanomedicine, ISSN: 17435889
Tarek M. Fahmy; Stacey L. Demento; Michael J. Caplan; Ira Mellman; W. Mark Saltzman
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High-resolution genomic and expression analyses of copy number alterations in breast tumors
Genes Chromosomes and Cancer, ISSN: 10452257 10982264
Matthias Peter; Jane Fridlyand; Li Li; Gad Getz; Rameen Beroukhim; Scott Lohr; Thomas D Wu; Guy Cavet; Zemin Zhang; John Chant
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Dendritic cells: Driving the differentiation programme of T cells in viral infections
Immunology and Cell Biology, ISSN: 08189641 14401711
Frederick Masson; Adele Mount; Nicholas S. Wilson; Gabrielle T Belz
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Quantitative determination of humanized monoclonal antibody rhuMAb2H7 in cynomolgus monkey serum using a Generic Immunoglobulin Pharmacokinetic (GRIP) assay
Journal of Immunological Methods, ISSN: 00221759
Yang; Carl Ng; Henry B. Lowman; Chestnut; Cheryl A. Schofield; Bryan Sandlund; James A. Ernst; Bennett; Quarmby
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Ubiquitin-mediated regulation of TNFR1 signaling
Cytokine and Growth Factor Reviews, ISSN: 13596101
Ingrid E. Wertz; Vishva M. Dixit
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Multiple sclerosis risk after optic neuritis: Final optic neuritis treatment trial follow-up
Archives of Neurology, ISSN: 00039942 15383687
Michael Brodsky; Sarkis Nazarian; Silvia Orengo-Nania; George J. Hutton; Edward G. Buckley; E. Wayne Massey; M. Tariq Bhatti; Melvin Greer; James Goodwin; Michael Wall; Peter J. Savino; Thomas Leist; Neil R. Miller; David Irani; Jonathan D. Trobe; Wayne Cornblath; David I. Kaufman; Eric Eggenberger; Mark J. Kupersmith; William T. Shults; Leslie McAllister; Steve Hamilton; Roy W. Beck; Mariya Dontchev; Robin L. Gal; Craig Kollman; John L. Keltner; Craig H. Smith
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(Un)expected roles of c-IAPs in apoptotic and NFκB signaling pathways
Cell Cycle, ISSN: 15514005 15384101
Eugene Varfolomeev; Domagoj Vucic
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MetMAb, the one-armed 5d5 anti-c-met antibody, inhibits orthotopic pancreatic tumor growth and improves survival
Cancer Research, ISSN: 00085472
Hongkui Jin; Renhui Yang; Zhong Zheng; Mally Romero; Ross; Hani Bou-Reslan; Richard A. D. Carano; Ian Kasman; Elaine Mai; Judy Young; Jiping Zha; Zemin Zhang; Ross; Ralph H. Schwall; Gail T. Colbern; Mark Merchant
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Role of P-glycoprotein and the intestine in the excretion of DPC 333 [(2R)-2-{(3R)-3-amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl] -2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in rodents
Drug Metabolism and Disposition, ISSN: 00909556 1521009X
C. Edwin Garner; Eric G. Solon; Chii-Ming Lai; Jianrong Lin; Gang Luo; Kevin Jones; Jingwu Duan; Carl P. Decicco; Thomas Maduskuie; Stephen E. Mercer; Lian-Shen Gan; Mingxin Qian; Shimoga Prakash; Huey-Shin Shen; Frank W. Lee
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Netrin-1 inhibits sprouting angiogenesis in developing avian embryos
Developmental Biology, ISSN: 00121606
Karine Bouvrée; Bruno Larrivee; Xiang Lv; Li Yuan; Benjamin DeLafarge; Catarina Freitas; Thomas Mathivet; Christiane Bréant; Marc Tessier-Lavigne; Andréas Bikfalvi; Anne Eichmann; Luc Pardanaud
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Targeting the extrinsic apoptosis pathway in cancer
Cytokine and Growth Factor Reviews, ISSN: 13596101
Avi Ashkenazi
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Use of quantitative pharmacology in the development of HAE1, a high-affinity anti-ige monoclonal antibody
AAPS Journal, ISSN: 15507416
Wendy Putnam; Jing Li; Jonas Haggstrom; Chee Ng; Saloumeh Kadkhodayan Fischer; Melissa Cheu; Yamo Deniz; Henry B. Lowman; Fielder; Jennifer Visich; Amita Joshi; Nelson L'ntshotsholé Jumbe
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In vitro Protein Refolding
Biotechnology: Second, Completely Revised Edition,
Cleland; Daniel I. C. Wang
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Proteins and Peptides as Drugs: Sources and Methods of Purification
Biotechnology: Second, Completely Revised Edition,
Stuart E. Builder; Robert L. Garnick; James C. Hodgdon; John R. Ogez
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On-line CE-LIF-MS technology for the direct characterization of N-linked glycans from therapeutic antibodies
Analytical Chemistry, ISSN: 00032700
Lynn Gennaro; Oscar Salas-Solano
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IgG regulates the CD1 expression profile and lipid antigen-presenting function in human dendritic cells via RrγRIIa
Blood, ISSN: 15280020 00064971
Anna Smed-Sörensen; Markus Moll; Tan-Yuri Cheng; Karin Loré; Anna-Carin Norlin; Leif Perbeck; D. Branch Moody; Anna-Lena Spetz; Johan K. Sandberg
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Regulation of epithelial branching morphogenesis and cancer cell growth of the prostate by Wnt signaling
PLoS ONE, ISSN: 19326203
Bu-Er Wang; Xi-De Wang; James A. Ernst; Paul G. Polakis; Gao
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The hominoid-specific oncogene TBC1d3 activates ras and modulates epidermal growth factor receptor signaling and trafficking
Journal of Biological Chemistry, ISSN: 00219258 1083351X
Marisa J. Wainszelbaum; Audra J. Charron; Chen Kong; Donald S. Kirkpatrick; Priya Srikanth; M. Alejandro Barbieri; Steven P. Gygi; Philip D. Stahl
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Alternative Splicing of the Robo3 Axon Guidance Receptor Governs the Midline Switch from Attraction to Repulsion
Neuron, ISSN: 08966273
Zhe Chen; Bryan B. Gore; Hua Long; Le Ma; Marc Tessier-Lavigne
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Proteins and Peptides as Drugs: Sources and Methods of Purification
Biotechnology: Second, Completely Revised Edition,
Stuart E. Builder; Robert L. Garnick; James C. Hodgdon; John R. Ogez
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In vitro Protein Refolding
Biotechnology: Second, Completely Revised Edition,
Cleland; Daniel I. C. Wang
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Manufacturing control systems bridge production and IT
Control Engineering, ISSN: 00108049
Ronald E. Menéndez; Darrell Tanner
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Efalizumab: Results of a 3-year continuous dosing study for the long-term control of psoriasis
British Journal of Dermatology, ISSN: 00070963 13652133
Craig Leonardi; Alan Menter; Tiffani K. Hamilton; Ivor Caro; Xing; Alice Gottlieb
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Topography of thalamic projections requires attractive and repulsive functions of netrin-1 in the ventral telencephalon
PLoS Biology, ISSN: 15449173 15457885
Ashton W. Powell; Takayuki Sassa; Yongqin Wu; Marc Tessier-Lavigne; Franck Polleux
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Second-line and third-line chemotherapy for lung cancer: Use and cost
American Journal of Managed Care, ISSN: 10880224
Scott D. Ramsey; Renato G. Martins; David Blough; Lauri S. Tock; Deborah Lubeck; Carolina Reyes
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Maturation modulates caspase-1-independent responses of dendritic cells to anthrax lethal toxin
Cellular Microbiology, ISSN: 14625814 14625822
Núria Reig; Aimin Jiang; Rachael Couture; Fayyaz S. Sutterwala; Yasunori Ogura; Richard A. Flavell; Ira Mellman; F. Gisou Van Der Goot
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Glioblastoma-derived stem cell-enriched cultures form distinct subgroups according to molecular and phenotypic criteria
Oncogene, ISSN: 09509232 14765594
Hauke S. Günther; Nils-Ole Schmidt; Phillips; Dirk Kemming; Samir Kharbanda; Robert Soriano; Zora Modrusan; Meissner; Manfred Westphal; Katrin Lamszus
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Role of haptoglobin on the uptake of native and β-chain [trimesoyl-(Lys82)β-(Lys82)β] cross-linked human hemoglobins in isolated perfused rat livers
Drug Metabolism and Disposition, ISSN: 00909556 1521009X
Edwin C. Y. Chow; Lichuan Liu; Noam Ship; Ronald H. Kluger; K. Sandy Pang
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An actively mixed mini-bioreactor for protein production from suspended animal cells
Biotechnology and Bioengineering, ISSN: 00063592 10970290
Jinpian Diao; Lincoln Young; Peng Zhou; Michael L. Shuler
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The nucleolar phosphatase Cdc14B is dispensable for chromosome segregation and mitotic exit in human cells
Cell Cycle, ISSN: 15514005 15384101
Eli Berdougo; Maxence V. Nachury; Peter K Jackson; Prasad V. Jallepalli
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Microphthalmia-associated transcription factor is a critical transcriptional regulator of melanoma inhibitor of apoptosis in melanomas
Cancer Research, ISSN: 00085472
Jasmin N. Dynek; Sara M. Chan; Jinfeng Liu; Jiping Zha; Wayne J. Fairbrother; Domagoj Vucic
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Purifying therapeutic monoclonal antibodies
Chemical Engineering Progress, ISSN: 03607275
Amit Mehta; Martha Lovato Tse; Jace Fogle; Amy Len; Roshan Shrestha; Nuno Fontes; Lebreton; Bradley Wolk; Robert Van Reis
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Change in serum measurements of cartilage oligomeric matrix protein and association with the development and worsening of radiographic hip osteoarthritis
Osteoarthritis and Cartilage, ISSN: 10634584
Chaganti; Ariella Kelman; Lui; Yao; Javaid; Bauer; Nevitt; Lane; for the Study of Osteoporotic Fractures Research Group (SOF)
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Role of FDA's drug information centers
American Journal of Health-System Pharmacy, ISSN: 10792082
Kavita C. Dada; Mary Kremzner; Sanjeev K. Bhanot; Renu Lal
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Specificity of the STAT4 genetic association for severe disease manifestations of systemic lupus erythematosus
PLoS Genetics, ISSN: 15537390 15537404
Kimberly E. Taylor; Elaine F. Remmers; Annette T. Lee; Ward Ortmann; Robert M. Plenge; Tian; Sharon A. Chung; Joanne Nititham; Geoffrey Hom; Amy H. Kao; F. Yesim Demirci; M. Ilyas Kamboh; Michelle Petri; Manzi; Daniel L. Kastner; Michael F. Seldin; Peter K. Gregersen; Timothy W. Behrens; Lindsey A. Criswell
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Spinophilin participates in information transfer at immunological synapses
Journal of Cell Biology, ISSN: 00219525 00219525
Ona Bloom; Juli Unternaehrer; Aimin Jiang; Jeoung-Sook Shin; Lélia Delamarre; Patrick Allen; Ira Mellman
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Recommendations on risk-based strategies for detection and characterization of antibodies against biotechnology products
Journal of Immunological Methods, ISSN: 00221759
Koren; Holly W. Smith; Elizabeth Shores; Gopi Shankar; Deborah Finco-Kent; Bonita Rup; Yu Chen Barrett; Viswanath Devanarayan; Boris Gorovits; Shalini Gupta; Thomas Parish; Quarmby; Michael Moxness; Steven J. Swanson; Gary Taniguchi; Linda A. Zuckerman; Christopher C. Stebbins; Mire-Sluis
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Recombinant human deoxyribonuclease I
Pharmaceutical Biotechnology: Fundamentals and Applications, Third Edition,
Lazarus; Wagener
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The Biological Functions of T Helper 17 Cell Effector Cytokines in Inflammation
Immunity, ISSN: 10747613
Wenjun Ouyang; Jay K. Kolls; Yan Zheng
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The Intrinsic Contributions of Tyrosine, Serine, Glycine and Arginine to the Affinity and Specificity of Antibodies
Journal of Molecular Biology, ISSN: 00222836
Sara Birtalan; Yingnan Zhang; Frederic A. Fellouse; Lily Shao; Gabriele Schaefer; Sachdev S. Sidhu
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Natural selection of protein structural and functional properties: A single nucleotide polymorphism perspective
Genome Biology, ISSN: 14747596 1474760X
Jinfeng Liu; Yan Zhang; Xingye Lei; Zemin Zhang
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Blocking Neuropilin-2 Function Inhibits Tumor Cell Metastasis
Cancer Cell, ISSN: 15356108
Maresa Caunt; Judy Mak; Wei-Ching Liang; Scott Stawicki; Qi Pan; Raymond K. Tong; Joe Kowalski; Calvin Ho; Hani Bou-Reslan; Ross; Berry; Ian Kasman; Constance Zlot; Zhiyong Cheng; Jennifer Le Couter; Ellen H. Filvaroff; Greg D. Plowman; Franklin V. Peale Jr.; French; Richard A. D. Carano; Alexander W. Koch; Yan Wu; Ryan J. Watts; Marc Tessier-Lavigne; Anil Bagri
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Developing and promoting an intranet site for a drug information service
American Journal of Health-System Pharmacy, ISSN: 10792082
Emily C. Costerison; Graham
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