Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 10151 - 10200 OF 15578 RESULTS

A novel exosite on coagulation factor VIIa and its molecular interactions with a new class of peptide inhibitors
Biochemistry, ISSN: 00062960
Roberge; Santell; Dennis; Eigenbrot; Dwyer; Lazarus
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Human T-lymphotropic virus type-1 p30 alters cell cycle G2 regulation of T lymphocytes to enhance cell survival
Retrovirology, ISSN: 17424690
Antara Datta; Lee Silverman; Andrew J. Phipps; Hajime Hiraragi; Lee Ratner; Michael D. Lairmore
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Antibody-drug conjugates targeted to CD79 for the treatment of non-Hodgkin lymphoma
Blood, ISSN: 00064971 00064971
Andrew G. Polson; Shang-Fan Yu; Kristi Elkins; Bing Zheng; Suzanna Clark; Gladys S. Ingle; Dionysos S. Slaga; Lynne Giere; Du; Christine Tan; Hongo; Alvin Gogineni; Mary J. Cole; Richard L. Vandlen; Jean-Philippe Stephan; Judy Young; Wesley S. Chang; Suzie J. Scales; Ross; Dan L. Eaton; Allen Ebens
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Response: Does Bid Play a Role in the DNA Damage Response?
Cell, ISSN: 00928674
Kaufmann; Lin Tai; Paul G. Ekert; David C.S. Huang; Fiona Norris; Ralph K. Lindemann; Ricky W. Johnstone; Vishva M. Dixit; Damien Arnoult; Andreas Strasser
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A ubiquitin-binding motif in the translesion DNA polymerase Rev1 mediates its essential functional interaction with ubiquitinated proliferating cell nuclear antigen in response to DNA damage
Journal of Biological Chemistry, ISSN: 00219258 1083351X
Adam Wood; Parie Garg; Peter M. J. Burgers
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Tissue factor: A mediator of inflammatory cell recruitment, tissue injury, and thrombus formation in experimental colitis
Journal of Experimental Medicine, ISSN: 00221007 00221007
Christoph Anthoni; Janice Russell; Katherine C. Wood; Karen Y. Stokes; Thorsten Vowinkel; Daniel Kirchhofer; D. Neil Granger
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Bioprocess membrane technology
Journal of Membrane Science, ISSN: 03767388
Robert Van Reis; Andrew Zydney
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The Nogo-66 receptor NgR1 is required only for the acute growth cone-collapsing but not the chronic growth-inhibitory actions of myelin inhibitors
Journal of Neuroscience, ISSN: 02706474 02706474
Onanong Chivatakarn; Shinjiro Kaneko; Zhigang He; Marc Tessier-Lavigne; Roman J. Giger
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Bcl-2 is the target of a UV-inducible apoptosis switch and a node for UV signaling
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Dejan Knezevic; Wengeng Zhang; Patrick J. Rochette; Douglas E. Brash
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Multiplex assay for comprehensive genotyping of genes involved in drug metabolism, excretion, and transport
Clinical Chemistry, ISSN: 00099147
Thomas M. Daly; Carmen M. Dumaual; Xin Miao; Mark W. Farmen; Reuben K. Njau; Dong-Jing Fu; Nancy L. Bauer; Sandra Close; Nancy Watanabe; Carsten Bruckner; Paul Hardenbol; Richard D. Hockett
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Characterization of the rat urokinase plasminogen activator receptor promoter in PC12 cells
Journal of Neuroscience Research, ISSN: 03604012 10974547
Feng Su; Kathy R. Kozak; Harvey Herschman; Srinivasa T. Reddy; Robin Farias-Eisner
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UNC5C is required for spinal accessory motor neuron development
Molecular and Cellular Neuroscience, ISSN: 10447431
Dillon; Jevince; Hinck; Ackerman; Lu; Marc Tessier-Lavigne; Kaprielian
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The Biflow: An instrument for transfer-loop mediated, continuous, preparative-scale isoelectric trapping separations
Electrophoresis, ISSN: 01730835 15222683
Evan Shave; Gyula Vigh
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GA-binding protein is dispensable for neuromuscular synapse formation and synapse-specific gene expression
Molecular and Cellular Biology, ISSN: 02707306
Alexander Jaworski; Cynthia L. Smith; Steven J. Burden
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Growth factors gene expression in the developing lung
Acta Paediatrica, International Journal of Paediatrics, ISSN: 08035253 16512227
Edward M. Mager; Gabriele Renzetti; Alexander Auais; Giovanni Piedimonte
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Metabolism, pharmacokinetics, and excretion of a nonpeptidic substance P receptor antagonist, ezlopitant, in normal healthy male volunteers: Characterization of polar metabolites by chemical derivatization with dansyl chloride
Drug Metabolism and Disposition, ISSN: 00909556 1521009X
Chandra Prakash; John O'Donnell; S. Cyrus Khojasteh
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Identification of a novel glutathione conjugate of flutamide in incubations with human liver microsomes
Drug Metabolism and Disposition, ISSN: 00909556 1521009X
Ping Kang; Deepak Dalvie; Evan Smith; Sue Zhou; Alan Deese
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CanPredict: A computational tool for predicting cancer-associated missense mutations
Nucleic Acids Research, ISSN: 03051048 13624962
Joshua S. Kaminker; Yan Zhang; Colin K. Watanabe; Zemin Zhang
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A phase I/II randomized open-label multicenter trial of efalizumab, a humanized anti-CD11a, anti-LFA-1 in renal transplantation
American Journal of Transplantation, ISSN: 16006135 16006143
Vincenti; Mendez; Pescovitz; Rajagopalan; Wilkinson; Butt; Laskow; Slakey; Lorber; Jay Garg; Marvin Garovoy
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The biology and therapeutic potential of interleukin 27
Journal of Molecular Medicine, ISSN: 09462716
Marcel Batten; Nico Ghilardi
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Response [2]
Journal of Magnetic Resonance Imaging, ISSN: 10531807 15222586
Joan M. Greve; Simon P. Williams
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GeneHub-GEPIS: Digital expression profiling for normal and cancer tissues based on an integrated gene database
Nucleic Acids Research, ISSN: 03051048 13624962
Yan Zhang; Shiuh-Ming Luoh; Lawrence S. Hon; Robert Baertsch; William I. Wood; Zemin Zhang
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Secreted sulfatases Sulf1 and Sulf2 have overlapping yet essential roles in mouse neonatal survival
PLoS ONE, ISSN: 19326203
Charles R. Holst; Hani Bou-Reslan; Bryan B. Gore; Karen Wong; Deanna Grant; Sreedevi Chalasani; Richard A. D. Carano; Gretchen D. Frantz; Marc Tessier-Lavigne; Brad Bolon; French; Avi Ashkenazi
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Epigenome scans and cancer genome sequencing converge on WNK2, a kinase-independent suppressor of cell growth
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Chibo Hong; K. Scott Moorefield; Peter Jun; Kenneth D. Aldape; Samir Kharbanda; Phillips; Joseph F. Costello
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2007 highlights of advance in the pharmaceutical sciences: An American Association of Pharmaceutical Scientists (AAPS) perspective
AAPS Journal, ISSN: 15507416
Marilyn N. Martinez; Peter Bonate; Robert L. Chapman; Anne De Groot; Susan D'Souza; Naushad Ghilazi; Vivian Gray; Vishal K. Gupta; Kim Huynh-Ba; Sunil Iyer; Arya Jayatilaka; Amita Joshi; H. Thomas Karnes; Mansoor Khan; Patrick Liu; Craig Lunte; Christopher R. McCurdy; Marilyn E. Morris; Kenneth J. Norris; Phillip Ramsey; Sanjay Sehgal; Manuel Zahn
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Inhibition of VEGF-A prevents the angiogenic switch and results in increased survival of Apc+/min mice
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Nina Korsisaari; Ian Kasman; William F. Forrest; Navneet Pal; Wei Bai; Fuh; Franklin V. Peale Jr.; Ron Smits; Napoleone Ferrara
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A Core Complex of BBS Proteins Cooperates with the GTPase Rab8 to Promote Ciliary Membrane Biogenesis
Cell, ISSN: 00928674
Maxence V. Nachury; Alexander V. Loktev; Qihong Zhang; Christopher J. Westlake; Johan Peränen; Andreas Merdes; Diane C. Slusarski; Richard H. Scheller; J.Fernando Bazan; Val C. Sheffield; Peter K Jackson
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Erratum: Armed antibodies targeting the mucin repeats of the ovarian cancer antigen, MUC16, are highly efficacious in animal tumor models (Cancer Research (2007) 67, (4924-4932))
Cancer Research, ISSN: 00085472
Youjun Chen; Suzanna Clark; Wong; Yongmei Chen; Chen; Dennis; Luis; Fiona Zhong; Sheila Bheddah; Koeppen; Alvin Gogineni; Paul G. Polakis; William Mallet
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A novel inhibitor of the alternative pathway of complement reverses inflammation and bone destruction in experimental arthritis
Journal of Experimental Medicine, ISSN: 00221007 00221007
Kenneth J. Katschke Jr.; Karim Y. Helmy; Micah Steffek; Hongkang Xi; Jianping Yin; Wyne P. Lee; Gribling; Kai H. Barck; Richard A. D. Carano; Taylor; Linda Rangell; Laurie Diehl; Hass; Wiesmann; Menno Van Lookeren Campagne
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Transitioning patients from efalizumab to alternative psoriasis therapies: Findings from an open-label, multicenter, Phase IIIb study
International Journal of Dermatology, ISSN: 00119059 13654632
Alan Menter; Tiffani K. Hamilton; Darryl P. Toth; Hoi M. Leung; Graham Wetherill; Brian Hennessey; Marvin Garovoy; Paul Kwon; David M. Pariser
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Characterization of protein-protein interactions critical for poliovirus replication: Analysis of 3AB and VPg binding to the RNA-dependent RNA polymerase
Journal of Virology, ISSN: 0022538X
Daniel M. Strauss; Deborah S. Wuttke
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The soluble Wnt receptor Frizzled8CRD-hFc inhibits the growth of teratocarcinomas in vivo
Cancer Research, ISSN: 00085472
Venita I. DeAlmeida; Li Miao; James A. Ernst; Koeppen; Paul G. Polakis; Bonnee Rubinfeld
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Real-world Evaluation of Asthma Control and Treatment (REACT): Findings from a national Web-based survey
Journal of Allergy and Clinical Immunology, ISSN: 00916749
Stephen P. Peters; Craig A. Jones; Tmirah Haselkorn; David R. Mink; David J. Valacer; Weiss
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Dendritic cell vaccine hits FDA roadblock.
Managed Care, ISSN: 10623388
Thomas Morrow
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Exploring and designing protein function with restricted diversity
Current Opinion in Chemical Biology, ISSN: 13675931
Sachdev S. Sidhu; Anthony A. Kossiakoff
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Presence of methicillin resistant Staphylococcus aureus in respiratory cultures from cystic fibrosis patients is associated with lower lung function
Pediatric Pulmonology, ISSN: 87556863 10990496
Clement L. Ren; Morgan; Michael W. Konstan; Michael S. Schechter; Wagener; Kathryn A. Fisher; Warren E. Regelmann
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Do deaf and hard of hearing youth need antitobacco education?
American Annals of the Deaf, ISSN: 0002726X
Barbara A. Herman; Leanne Streja; Coen A. Bernaards; Elizabeth A. Eckhardt; Heidi B. Kleiger; Lauren Maucere; Glenn Wong; Shari Barkin; Roshan Bastani
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A pilot study of tumor necrosis factor inhibition in erosive/inflammatory osteoarthritis of the hands
Journal of Rheumatology, ISSN: 0315162X
Molly D. Magnano; Eliza F. Chakravarty; Corrie Broudy; Lorinda Chung; Ariella Kelman; Jennifer Hillygus; Mark C. Genovese
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Nerve growth factor mediates steroid-resistant inflammation in respiratory syncytial virus infection
Pediatric Pulmonology, ISSN: 87556863 10990496
Lida Mohtasham; Alexander Auais; Giovanni Piedimonte
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Association of control and risk of severe asthma-related events in severe or difficult-to-treat asthma patients
Allergy: European Journal of Allergy and Clinical Immunology, ISSN: 01054538 13989995
Sean D. Sullivan; Sally E. Wenzel; Bresnahan; Zheng; June H. Lee; Pritchard; Tripthi V. Kamath; Weiss
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Identifying specificity profiles for peptide recognition modules from phage-displayed peptide libraries
Nature Protocols, ISSN: 17542189 17502799
Raffi Tonikian; Yingnan Zhang; Charles Boone; Sachdev S. Sidhu
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Safety outcomes of Alteplase among acute ischemic stroke patients with special characteristics
Neurocritical Care, ISSN: 15416933
Sylaja; Wei Dong; James C. Grotta; Mary K. Miller; Kristen Tomita; Scott Hamilton; Charles P. Semba; Michael D. Hill
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Structure of the catalytic domain of human polo-like kinase 1
Biochemistry, ISSN: 00062960
Michael Kothe; Darcy Kohls; Simon Low; Rocco Coli; Alan C. Cheng; Suzanne L. Jacques; Theresa L. Johnson; Lewis; Christine Loh; Jim Nonomiya; Alissa L. Sheils; Kimberly A. Verdries; Thomas A. Wynn; Cyrille Kuhn; Yuan-Hua Ding
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Armed antibodies targeting the mucin repeats of the ovarian cancer antigen, MUC16, are highly efficacious in animal tumor models
Cancer Research, ISSN: 00085472
Youjun Chen; Suzanna Clark; Wong; Yongmei Chen; Chen; Dennis; Luis; Fiona Zhong; Sheila Bheddah; Koeppen; Alvin Gogineni; Paul G. Polakis; William Mallet
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Targeting VEGF-A to treat cancer and age-related macular degeneration
Annual Review of Medicine, ISSN: 00664219
Napoleone Ferrara; Robert Mass; Claudio Campa; Robert Kim
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Full-length antibodies on display
Nature Biotechnology, ISSN: 10870156 15461696
Sachdev S. Sidhu
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Demographic and clinical characteristics of children and adolescents with severe or difficult-to-treat asthma
Journal of Allergy and Clinical Immunology, ISSN: 00916749
Bradley E. Chipps; Stanley J. Szefler; F. Estelle R. Simons; Tmirah Haselkorn; David R. Mink; Yamo Deniz; June H. Lee
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Selective clearance of glycoforms of a complex glycoprotein pharmaceutical caused by terminal N-acetylglucosamine is similar in humans and cynomolgus monkeys
Glycobiology, ISSN: 09596658 14602423
Andrew J.S. Jones; Damon I. Papac; Chin; Rodney Keck; Sharon A. Baughman; Yvonne S. Lin; Johannes Kneer; John E. Battersby
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Monoclonal antibody now available to prevent red blood cell breakdown.
Managed Care, ISSN: 10623388
Thomas Morrow
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Quantitative translational pharmacology for monoclonal antibody dose and dose-schedule determination
American Pharmaceutical Review, ISSN: 10998012
Nelson L'ntshotsholé Jumbe
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