Scientists / Publications

Publications

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DISPLAYING 6801 - 6850 OF 15217 RESULTS

Vascular physiology and protein disposition in a preclinical model of neurodegeneration
Molecular Pharmaceutics, ISSN: 15438384 15438392
C. Andrew Boswell; Eduardo E. Mundo; Bernadette Johnstone; Sheila Ulufatu; Michelle G. Schweiger; Daniela Bumbaca; Fielder; Saileta Prabhu; Leslie A. Khawli
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Drug delivery across the blood-brain barrier
Molecular Pharmaceutics, ISSN: 15438392 15438384
Leslie A. Khawli; Saileta Prabhu
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Plasma Epstein-Barr virus DNA predicts outcome in advanced Hodgkin lymphoma: Correlative analysis from a large North American cooperative group trial
Blood, ISSN: 15280020 00064971
Jennifer A. Kanakry; Hailun Li; Lan L. Gellert; M. Victor Lemas; Wen-Son Hsieh; Fangxin Hong; King L. Tan; Randy D. Gascoyne; Leo I. Gordon; Richard I. Fisher; Nancy L. Bartlett; Patrick J. Stiff; Bruce D. Cheson; Ranjana H. Advani; Thomas P. Miller; Brad Kahl; Sandra J. Horning; Richard F. Ambinder
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Inactivation of TP53 correlates with disease progression and low miR-34a expression in previously treated chronic lymphocytic leukemia patients
Blood, ISSN: 15280020 00064971
Annika Dufour; Palermo; Evelyn Zellmeier; Gudrun Mellert; Guillemette Duchateau-Nguyen; Stephanie Schneider; Tobias Benthaus; Purvi M. Kakadia; Karsten Spiekermann; Wolfgang Hiddemann; Jan Braess; Sim Truong; Nancy Patten; Lin Wu; Sabine Lohmann; David Dornan; Debraj GuhaThakurta; Ru-Fang Yeh; Galina Salogub; Philippe Solal-Celigny; Anna Dmoszynska; Tadeusz Robak; Marco Montillo; John Catalano; Christian H. Geisler; Martin Weisser; Stefan K. Bohlander
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Plasma Epstein-Barr virus DNA predicts outcome in advanced Hodgkin lymphoma: Correlative analysis from a large North American cooperative group trial
Blood, ISSN: 15280020 00064971
Jennifer A. Kanakry; Hailun Li; Lan L. Gellert; M. Victor Lemas; Wen-Son Hsieh; Fangxin Hong; King L. Tan; Randy D. Gascoyne; Leo I. Gordon; Richard I. Fisher; Nancy L. Bartlett; Patrick J. Stiff; Bruce D. Cheson; Ranjana H. Advani; Thomas P. Miller; Wojciech Jurczak; Sandra J. Horning; Richard F. Ambinder
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GPU-accelerated nonparametric kinetic analysis of DCE-MRI data from glioblastoma patients treated with bevacizumab
Magnetic Resonance Imaging, ISSN: 0730725X 18735894
Yu-Han H. Hsu; Gregory Z. Ferl; Chee Ng
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PK assays for antibody-drug conjugates: Case study with ado-trastuzumab emtansine
Bioanalysis, ISSN: 17576180 17576199
Randall Dere; Joo-Hee Yi; Corinna Lei; Ola M. Saad; Catherine Huang; Yanhong Li; Jakub Baudys; Surinder Kaur
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Immunogenicity assays for antibody-drug conjugates: Case study with ado-trastuzumab emtansine
Bioanalysis, ISSN: 17576180 17576199
Montserrat Carrasco-Triguero; Joo-Hee Yi; Randall Dere; Zhihua Julia Qiu; Corinna Lei; Yanhong Li; Connie Mahood; Wang; Douglas Leipold; Kirsten Achilles Poon; Surinder Kaur
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Identifying the mesenchymal molecular subtype of glioblastoma using quantitative volumetric analysis of anatomic magnetic resonance images
Neuro-Oncology, ISSN: 15228517 15235866
Kourosh M. Naeini; Whitney B. Pope; Timothy Cloughesy; Robert J. Harris; Albert Lai; Ascia Eskin; Reshmi Chowdhury; Phillips; Phioanh L. Nghiemphu; Yalda Behbahanian; Benjamin M. Ellingson
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Use of "MGE Enhancers" for Labeling and Selection of Embryonic Stem Cell-Derived Medial Ganglionic Eminence (MGE) Progenitors and Neurons
PLoS ONE, ISSN: 19326203
Ying-Jiun J. Chen; Daniel Vogt; Yanling Wang; Axel Visel; Shanni N. Silberberg; Cory Nicholas; Teruko Danjo; Joshua L. Pollack; Len A. Pennacchio; Stewart Anderson; Yoshiki Sasai; Scott C. Baraban; Arnold R. Kriegstein; Arturo Alvarez-Buylla; John L. R. Rubenstein
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Resilient immortals, characterizing and utilizing Bax/Bak deficient Chinese hamster ovary (CHO) cells for high titer antibody production
Biotechnology Progress, ISSN: 87567938 15206033
Shahram Misaghi; Yan Qu; Andrew Snowden; Chang; Snedecor
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Coordinated transcriptional regulation of bone homeostasis by Ebf1 and Zfp521 in both mesenchymal and hematopoietic lineages
Journal of Experimental Medicine, ISSN: 00221007 15409538
Riku Kiviranta; Kei Yamana; Hiroaki Saito; Daniel K. Ho; Julius Laine; Kati Tarkkonen; Vappu Nieminen-Pihala; Eric Hesse; Diego Correa; Jorma Määttä; Lino Tessarollo; Evan D. Rosen; William C. Horne; Nancy A. Jenkins; Neal G. Copeland; Søren Warming; Roland Baron
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Twelve-month efficacy and safety of 0.5 mg or 2.0 mg ranibizumab in patients with subfoveal neovascular age-related macular degeneration
Ophthalmology, ISSN: 15494713 01616420
Brandon G. Busbee; Allen C. Ho; David M. Brown; Jeffrey S. Heier; Ivan J. Suñer; Zhengrong Li; Roman G. Rubio; Phillip Lai
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P21-activated kinase 1 (PAK1) as a therapeutic target in BRAF wild-type melanoma
Journal of the National Cancer Institute, ISSN: 00278874 14602105
Christy C. Ong; Adrian M. Jubb; Diana Jakubiak; Wei Zhou; Joachim Rudolph; Matthias Peter; Marcin Kowanetz; Yibing Yan; Jarrod Tremayne; Richard Lisle; Adrian L. Harris; Lori S. Friedman; Marcia Belvin; Mark R. Middleton; Elizabeth M. Blackwood; Koeppen; Klaus P. Hoeflich
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Loss of Gsx1 and Gsx2 function rescues distinct phenotypes in Dlx1/2 mutants
Journal of Comparative Neurology, ISSN: 00219967 10969861
Bei Wang; Jason E. Long; Pierre Flandin; Ramon Pla; Ronald R. Waclaw; Kenneth Campbell; John L. R. Rubenstein
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A note on variance estimation in the Cox proportional hazards model
Journal of Applied Statistics, ISSN: 02664763 13600532
Jiong Luo; Zheng Su
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An entirely automated method to score DSS-induced colitis in mice by digital image analysis of pathology slides
DMM Disease Models and Mechanisms, ISSN: 17548403 17548411
Cleopatra Kozlowski; Surinc Er Jeet; Joseph Beyer; Steve Guerrero; Justin Lesch; Xiaoting Wang; Jason Devoss; Laurie Diehl
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First-line treatment patterns and clinical outcomes in patients with HER2-positive and hormone receptor-positive metastatic breast cancer from registHER
Oncologist, ISSN: 10837159 1549490X
Debasish Tripathy; Peter A. Kaufman; Adam Brufsky; Musa Mayer; Marianne Ulcickas Yood; Bongin Yoo; Quah; Denise A. Yardley; Hope S. Rugo
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Characterization of the drug-to-antibody ratio distribution for antibody-drug conjugates in plasma/serum
Bioanalysis, ISSN: 17576180 17576199
Keyang Xu; Luna Liu; Randall Dere; Elaine Mai; Rebecca Erickson; Angela Hendricks; Kedan Lin; Jagath R. Junutula; Surinder Kaur
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Determination of clinically therapeutic endoxifen concentrations based on efficacy from human MCF7 breast cancer xenografts
Breast Cancer Research and Treatment, ISSN: 01676806 15737217
Inna Y. Gong; Wendy A. Teft; Justin Ly; Yunghsiang Chen; Bruno Alicke; Richard B. Kim; Edna F. Choo
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Discovery of thiazolobenzoxepin PI3-kinase inhibitors that spare the PI3-kinase β isoform
Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X 14643405
Steven T. Staben; Chudi O. Ndubaku; Nicole Blaquiere; Marcia Belvin; Richard J. Bull; Danette Dudley; Kyle A. Edgar; Daniel C. Gray; Robert Heald; Timothy P. Heffron; Graham Jones; Mark Jones; Aleksandr Kolesnikov; Leslie Lee; John Lesnick; Lewis; Jeremy Murray; Neville J. McLean; Jim Nonomiya; Alan G. Olivero; Rachel Ord; Jodie Pang; Stephen Price; Wei Wei Prior; Lionel Rouge; Laurent Salphati; Deepak Sampath; Jeffery J. Wallin; Lan Wang; Binqing Wei; Christian Weismann; Ping Wu
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A likelihood and resampling based approach to dichotomizing a continuous biomarker in medical research
Journal of Biopharmaceutical Statistics, ISSN: 10543406 15205711
Min Su; Liang Fang; Zheng Su
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8th annual european antibody congress 2012: November 27-28, 2012, Geneva, Switzerland
mAbs, ISSN: 19420862 19420870
Alain Beck; Paul J. Carter; Hans-Peter Gerber; Alexey A. Lugovskoy; Thierry Wurch; Jagath R. Junutula; Roland Kontermann; Robert Mabry
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Predictive value in retinal vein occlusions of early versus late or incomplete ranibizumab response defined by optical coherence tomography
Ophthalmology, ISSN: 01616420 15494713
Robert B. Bhisitkul; Peter A. Campochiaro; Howard Shapiro; Roman G. Rubio
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Safety of rituximab in combination with other biologic disease-modifying antirheumatic drugs in rheumatoid arthritis: An open-label study
Journal of Rheumatology, ISSN: 0315162X 14992752
William F. Rigby; Philip J. Mease; Ewa Olech; Ashby; Swati Tole
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Pertuzumab, trastuzumab, and docetaxel for HER2-positive metastatic breast cancer (CLEOPATRA study): Overall survival results from a randomised, double-blind, placebo-controlled, phase 3 study
The Lancet Oncology, ISSN: 14702045 14745488
Sandra M. Swain; Sung-Bae Kim; Javier Cortés; Jungsil Ro; Vladimir Semiglazov; Mario Campone; Eva Ciruelos; Jean-Marc Ferrero; Andreas Schneeweiss; Adam Knott; Emma Clark; Graham Ross; Benyunes; Baselga
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Dr. Keystone, et al, reply
Journal of Rheumatology, ISSN: 0315162X 14992752
Edward Keystone; Stanley B. Cohen; Paul Emery; Joel M. Kremer; Maxime Dougados; James E. Loveless; Carol Y. Chung; Pamela Wong; Lehane; Helen Tyrrell
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Development of a new bioprocess scheme using frozen seed train intermediates to initiate CHO cell culture manufacturing campaigns
Biotechnology and Bioengineering, ISSN: 00063592 10970290
Gargi Seth; Robert W. Hamilton; Stapp; Lisa Zheng; Angela Meier; Krista Petty; Stephenie Leung; Srikanth Chary
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Bioanalysis special focus issue on antibody-drug conjugates
Bioanalysis, ISSN: 17576180 17576199
Surinder Kaur
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Bioanalysis of antibody-drug conjugates: American Association of Pharmaceutical Scientists Antibody-Drug Conjugate Working Group position paper
Bioanalysis, ISSN: 17576180 17576199
Boris Gorovits; Stephen C. Alley; Sanela Bilic; Brian Booth; Surinder Kaur; Phillip Oldfield; Shobha Purushothama; Chetana Rao; Stacy Shord; Patricia Siguenza
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Data acquisition and data mining techniques for metabolite identification using LC coupled to high-resolution MS
Bioanalysis, ISSN: 17576180 17576199
Shuguang Ma; Swapan K. Chowdhury
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Newer developments in HPLC impacting pharmaceutical analysis: A brief review
American Pharmaceutical Review, ISSN: 10998012
Michael W. Dong; Davy Guillarme
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Recapitulating human cancer in a mouse
Nature Biotechnology, ISSN: 10870156 15461696
Lynda Chin; Frederic J. De Sauvage; Mikala Egeblad; Kenneth P. Olive; David Tuveson; William Weiss
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Addressing safety liabilities of TfR bispecific antibodies that cross the blood-brain barrier
Science Translational Medicine, ISSN: 19466234 19466242
Jessica A. Couch; Y. Joy Yu; Yin Zhang; Jacqueline M. Tarrant; Reina N. Fuji; William J. Meilandt; Hilda Solanoy; Raymond K. Tong; Kwame Hoyte; Wilman Luk; Yanmei Lu; Kapil Gadkar; Saileta Prabhu; Benjamin A. Ordonia; Quyen Nguyen; Yuwen L. Lin; Zhonghua Lin; Mercedesz Balazs; Kimberly Scearce-Levie; James A. Ernst; Dennis; Ryan J. Watts
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Strategies to address drug interaction potential for antibody-drug conjugates in clinical development
Bioanalysis, ISSN: 17576180 17576199
Dan Lu; Srikumar Sahasranaman; Yi Zhang; Sandhya Girish
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Structural basis of signaling blockade by anti-IL-13 antibody Lebrikizumab
Journal of Molecular Biology, ISSN: 10898638 00222836
Ultsch; Jack Bevers; Nakamura; Richard L. Vandlen; Robert F. Kelley; Lawren C. Wu; Eigenbrot
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EGFR Inhibitor Erlotinib Delays Disease Progression but Does Not Extend Survival in the SOD1 Mouse Model of ALS
PLoS ONE, ISSN: 19326203
Claire E. Le Pichon; Sara L. Dominguez; Hilda Solanoy; Hai Ngu; Nicholas Lewin-Koh; Mark Chen; Jeffrey Eastham-Anderson; Ryan J. Watts; Kimberly Scearce-Levie
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Spirocyclic β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors: From hit to lowering of cerebrospinal fluid (CSF) amyloid β in a higher species
Journal of Medicinal Chemistry, ISSN: 15204804 00222623
Kevin W. Hunt; Adam W. Cook; Ryan J. Watts; Christopher T. Clark; Guy Vigers; Darin Smith; Andrew T. Metcalf; Indrani W. Gunawardana; Michael Burkard; April Cox; Mary K. Geck Do; Darrin Dutcher; Allen A. Thomas; Sumeet Rana; Nicholas C. Kallan; Robert K. Delisle; James P. Rizzi; Kelly Regal; Douglas Sammond; Robert Groneberg; Michael Siu; Hans E. Purkey; Joseph P. Lyssikatos; Allison Marlow; Xingrong Liu; Tony P. Tang
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Structure of a complex phosphoglycan epitope from gp72 of Trypanosoma cruzi
Journal of Biological Chemistry, ISSN: 00219258 1083351X
Simon Allen; Julia M. Richardson; Angela Mehlert; Michael A. J. Ferguson
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Recent insights into the complexity of Tank-binding kinase 1 signaling networks: The emerging role of cellular localization in the activation and substrate specificity of TBK1
FEBS Letters, ISSN: 00145793 18733468
Elizabeth Helgason; Qui Phung; Erin C. Dueber
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OTUB1 modulates c-IAP1 stability to regulate signalling pathways
EMBO Journal, ISSN: 02614189 14602075
Tatiana Goncharov; Kyle Niessen; Maria Cristina De Almagro; Anita Izrael-Tomasevic; Anna V. Fedorova; Eugene Varfolomeev; David Arnott; Deshayes; Donald S. Kirkpatrick; Domagoj Vucic
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Phosphoproteomic analysis implicates the mTORC2-FoxO1 axis in VEGF signaling and feedback activation of receptor tyrosine kinases
Science Signaling, ISSN: 19450877 19379145
Guanglei Zhuang; Kebing Yu; Zhaoshi Jiang; Alicia S Chung; Jenny Yao; Connie Ha; Toy; Robert Soriano; Benjamin Haley; Elizabeth M. Blackwood; Deepak Sampath; Carlos Bais; Jennie R. Lill; Napoleone Ferrara
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Science signaling podcast: 16 April 2013
Science Signaling, ISSN: 19450877 19379145
Guanglei Zhuang; Napoleone Ferrara; Annalisa M. VanHook
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Exploring the effects of omalizumab in allergic asthma: An analysis of biomarkers in the EXTRA study
American Journal of Respiratory and Critical Care Medicine, ISSN: 1073449X 15354970
Nicola A. Hanania; Sally E. Wenzel; Karin Rosén; Hsin-Ju Hsieh; Mosesova; David F. Choy; Preeti Lal; Joseph R. Arron; Harris; William W. Busse
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Mutational tail loss is an evolutionary mechanism for liberating marapsins and other type i serine proteases Fromtransmembrane anchors
Journal of Biological Chemistry, ISSN: 00219258 1083351X
Kavita Raman; Neil N. Trivedi; Wilfred W. Raymond; Rajkumar Ganesan; Daniel Kirchhofer; George M. Verghese; Charles S. Craik; Eric L. Schneider; Shilpa Nimishakavi; George H. Caughey
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Kilogram synthesis of (S)-3-aminopyran from l -glutamic acid
Synlett, ISSN: 09365214 14372096
Scott Savage; Srinivasan Babu; Mark Zak; Zhongping Mao; Jianhua Cao; Yonghui Ge; Dongxu Ma; Guoqiang Jiang
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Pyrimidoaminotropanes as potent, selective, and efficacious small molecule kinase inhibitors of the mammalian target of rapamycin (mTOR)
Journal of Medicinal Chemistry, ISSN: 00222623 15204804
Anthony A. Estrada; Daniel G. Shore; Elizabeth M. Blackwood; Yunghsiang Chen; Gauri Deshmukh; Xiao Ding; Antonio G. DiPasquale; Jennifer A. Epler; Lori S. Friedman; Michael F. T. Koehler; Lichuan Liu; Shiva Malek; Jim Nonomiya; Daniel F. Ortwine; Zhonghua Pei; Steve Sideris; Frederic St-Jean; Lan Trinh; Tom Truong; Joseph P. Lyssikatos
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The role of the FcGRIIIa polymorphism in modifying the association between treatment and outcome in patients with rheumatoid arthritis treated with rituximab versus TNF-α antagonist therapies
Clinical and Experimental Rheumatology, ISSN: 0392856X 1593098X
Khaled Sarsour; Greenberg; Joseph A. Johnston; David R. Nelson; Lee A. O'Brien; Carole Oddoux; Harry Ostrer; Alex Pearlman; Reed
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In Vitro and In Vivo Assays
Drug Discovery: Practices, Processes, and Perspectives,
Adam R. Johnson
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Oncogenic RAS pathway activation promotes resistance to anti-VEGF therapy through G-CSF-induced neutrophil recruitment
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424 10916490
Vernon T. Phan; Xiumin Wu; Jason H. Cheng; Rebecca X. Sheng; Alicia S Chung; Guanglei Zhuang; Christopher Tran; Qinghua Song; Marcin Kowanetz; Amy Sambrone; Martha Tan; Meng; Erica L. Jackson; Franklin V. Peale Jr.; Melissa Junttila; Napoleone Ferrara
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