Scientists / Publications

Publications

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DISPLAYING 7301 - 7350 OF 15217 RESULTS

European genetic ancestry is associated with a decreased risk of lupus nephritis
Arthritis and Rheumatism, ISSN: 00043591 15290131
Ilana B. Richman; Kimberly E. Taylor; Sharon A. Chung; Laura Trupin; Michelle Petri; Edward Yelin; Robert R. Graham; Annette T. Lee; Timothy W. Behrens; Peter K. Gregersen; Michael F. Seldin; Lindsey A. Criswell
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Cost utility of palivizumab prophylaxis among pre-term infants in the United States: A national policy perspective
Journal of Medical Economics, ISSN: 13696998 1941837X
Parthiv J. Mahadevia; Anthony Masaquel; Mark J. Polak; Leonard B. Weiner
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Risk of Significant Infection in Rheumatoid Arthritis Patients Switching Anti-Tumor Necrosis Factor-α Drugs
Seminars in Arthritis and Rheumatism, ISSN: 00490172 1532866X
Bao-Anh Nguyen-Khoa; Earl L. Goehring; Kimberly Alexander; Wei Dong; Pavel Napalkov; Judith K. Jones
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The genetics of type I interferon in systemic lupus erythematosus
Current Opinion in Immunology, ISSN: 09527915 18790372
Paola G. Bronson; Christina Chaivorapol; Ward Ortmann; Timothy W. Behrens; Robert R. Graham
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Mycobacterium marinum SecA2 promotes stable granulomas and induces tumor necrosis factor alpha in Vivo
Infection and Immunity, ISSN: 00199567 10985522
Brigitte Y. Watkins; Shilpa A. Joshi; David A. Ball; Hadley Leggett; Summer Park; Janice Kim; Cary D. Austin; Andres Paler Martinez; Min Xu; Kenneth H. Downing; Eric J. Brown
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Genomic landscape of liver cancer
Nature Genetics, ISSN: 10614036 15461718
Zemin Zhang
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Myeloid cell tissue factor does not contribute to venous thrombogenesis in an electrolytic injury model
Thrombosis Research, ISSN: 00493848 18792472
Anna L. Hampton; Jose A. Diaz; Angela E. Hawley; Shirley K. Wrobleski; Jian-Guo Wang; Rebecca D. Lee; Daniel Kirchhofer; Robert E. Sigler; Thomas W. Wakefield; Nigel Mackman; Daniel D. Myers Jr.
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Cerebrovascular accidents in patients treated for choroidal neovascularization with ranibizumab in randomized controlled trials
Retina, ISSN: 0275004X 15392864
Neil M. Bressler; David S. Boyer; David F. Williams; Steven Butler; Steve Francom; Benton Brown; Flavia Di Nucci; Timothy Cramm; Lisa Tuomi; Tsontcho Ianchulev; Roman G. Rubio
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Immuno-PET of the hepatocyte growth factor receptor met using the 1-armed antibody onartuzumab
Journal of Nuclear Medicine, ISSN: 01615505
Elaine M. Jagoda; Lixin Lang; Veerendra Bhadrasetty; Stephanie Histed; Mark Williams; Gabriela Kramer-Marek; Esther Mena; Lauren Rosenblum; Jan Marik; Jeff N. Tinianow; Mark Merchant; Lawrence Szajek; Chang Paik; Fabiola Cecchi; Kristen Raffensperger; Joe-Marie Jose-Dizon; Donald P. Bottaro; Peter Choyke
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A phase i study of subcutaneously administered aflibercept (VEGF trap) in a new formulation in patients with advanced solid tumors
Investigational New Drugs, ISSN: 01676997 15730646
Andrea Wang-Gillam; William P. Tew; MacE L. Rothenberg; Jakob Dupont; Wendy Cooper; Lars Sternas; Giliane Buzenet; Jeffrey A. Sosman; David R. Spriggs; Albert Craig Lockhart
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Semi-mechanistic population pharmacokinetic model of multivalent trastuzumab emtansine in patients with metastatic breast cancer
Clinical Pharmacology and Therapeutics, ISSN: 00099236 15326535
Chudasama; Franziska Schaedeli-Stark; Harrold; Jay Tibbitts; Sandhya Girish; Manish Gupta; Frey; Donald E. Mager
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Intracellular-signaling tumor-regression modeling of the pro-apoptotic receptor agonists dulanermin and conatumumab
Journal of Pharmacokinetics and Pharmacodynamics, ISSN: 1567567X 15738744
Brittany P. Kay; Cheng-Pang Hsu; Jian-Feng Lu; Sun; Shuang Bai; Yan Xin; David Z. D'Argenio
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Modulation of caenorhabditis elegans infection sensitivity by the LIN-7 cell junction protein
Cellular Microbiology, ISSN: 14625814 14625822
Xiaohui Sem; Jason F. Kreisberg; Trupti Kawli; Man-Wah Tan; Mikael Rhen; Patrick Tan
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TBC1D13 is a RAB35 Specific GAP that Plays an Important Role in GLUT4 Trafficking in Adipocytes
Traffic, ISSN: 13989219 16000854
Jonathan R. Davey; Sean J. Humphrey; Jagath R. Junutula; Ashwini K. Mishra; David G. Lambright; David E. James; Jacqueline Stöckli
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Pyrazolopyridine inhibitors of B-RafV600E. Part 4: Rational design and kinase selectivity profile of cell potent type II inhibitors
Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X 14643405
Steve Wenglowsky; David Moreno; Ellen R. Laird; Susan L. Gloor; Li Ren; Tyler Risom; Joachim Rudolph; Hillary L. Sturgis; Walter C. Voegtli
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FcRL5 as a target of antibody-drug conjugates for the treatment of multiple myeloma
Molecular Cancer Therapeutics, ISSN: 15357163 15388514
Kristi Elkins; Bing Zheng; MaryAnn Go; Dionysos S. Slaga; Du; Suzie J. Scales; Shang-Fan Yu; Jacqueline McBride; Ruth De Tute; Andy Rawstron; Andrew S. Jack; Allen Ebens; Andrew G. Polson
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Single-stranded microRNA mimics
RNA, ISSN: 13558382 14699001
Guillaume Chorn; Molly Klein-Mcdowell; Lihong Zhao; Matthew A. Saunders; W. Michael Flanagan; Aarron T. Willingham; Lee P. Lim
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A population pharmacokinetic/pharmacodynamic model of thrombocytopenia characterizing the effect of trastuzumab emtansine (T-DM1) on platelet counts in patients with HER2-positive metastatic breast cancer
Cancer Chemotherapy and Pharmacology, ISSN: 03445704 14320843
Brendan C. Bender; Franziska Schaedeli-Stark; Reinhold Koch; Amita Joshi; Yu-Waye Chu; Hope S. Rugo; Ian E. Krop; Sandhya Girish; Lena E. Friberg; Manish Gupta
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Quantifying the exact allocation ratios in randomized clinical trials with biased coin randomization
Computer Methods and Programs in Biomedicine, ISSN: 01692607 18727565
Yunzhi Lin; Zheng Su
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Emerging evidence of epithelial-to-mesenchymal transition in lung carcinogenesis
Respirology, ISSN: 13237799 14401843
Sato; David S. Shames; Yoshinori Hasegawa
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Right- and left-loop short shRNAs have distinct and unusual mechanisms of gene silencing
Nucleic Acids Research, ISSN: 03051048 13624962
Anne Dallas; Heini Ilves; Qing Ge; Pavan Kumar; Joshua Shorenstein; Sergei A. Kazakov; Trinna L. Cuellar; Michael T. McManus; Mark A. Behlke; Brian H. Johnston
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Racial differences in presentation and management of follicular non-Hodgkin lymphoma in the United States: Report from the National LymphoCare Study
Cancer, ISSN: 0008543X 10970142
Chadi Nabhan; Michelle Byrtek; Taylor; Jonathan W. Friedberg; James R. Cerhan; John Hainsworth; Thomas P. Miller; Jamie Hirata; Brian K. Link; Christopher R. Flowers
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Treatment patterns and clinical outcomes in elderly patients with HER2-positive metastatic breast cancer from the registHER observational study
Breast Cancer Research and Treatment, ISSN: 01676806 15737217
Peter A. Kaufman; Adam Brufsky; Musa Mayer; Hope S. Rugo; Debasish Tripathy; Marianne Ulcickas Yood; Shibao Feng; Lisa I. Wang; Quah; Denise A. Yardley
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Improved vision-related function after ranibizumab for macular edema after retinal vein occlusion: Results from the BRAVO and CRUISE trials
Ophthalmology, ISSN: 01616420 15494713
Rohit Varma; Neil M. Bressler; Ivan J. Suñer; Paul P. Lee; Chantal M. Dolan; James Ward; Shoshana Colman; Roman G. Rubio
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Cerebrovascular accidents in patients treated for choroidal neovascularization with ranibizumab in randomized controlled trials
Retina, ISSN: 0275004X 15392864
Neil M. Bressler; David S. Boyer; David F. Williams; Butler; Steve Francom; Benton Brown; Flavia Di Nucci; Timothy Cramm; Lisa Tuomi; Tsontcho Ianchulev; Roman G. Rubio
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Foxp3 exploits a pre-existent enhancer landscape for regulatory T cell lineage specification
Cell, ISSN: 10974172 00928674
Robert M. Samstein; Aaron Arvey; Steven Z. Josefowicz; Xiao Peng; Alex Reynolds; Richard Sandstrom; Shane Neph; Peter Sabo; Kim; Will Liao; Ming Li; Christina Leslie; John A. Stamatoyannopoulos; Alexander Y. Rudensky
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Role of SHP2 phosphatase in KIT-induced transformation: Identification of SHP2 as a druggable target in diseases involving oncogenic KIT
Blood, ISSN: 15280020 00064971
Raghuveer Singh Mali; Peilin Ma; Li-Fan Zeng; Holly Martin; Baskar Ramdas; Yantao He; Emily Sims; Sarah Nabinger; Joydeep Ghosh; Namit Sharma; Veerendra Munugalavadla; Anindya Chatterjee; Shuo Li; Sandusky; Andrew W. Craig; Kevin D. Bunting; Gen-Sheng Feng; Rebecca J. Chan; Zhong-Yin Zhang; Reuben Kapur
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Discovery and preclinical pharmacology of a selective ATP-competitive Akt inhibitor (GDC-0068) for the treatment of human tumors
Journal of Medicinal Chemistry, ISSN: 00222623 15204804
James F. Blake; Rui Xu; Josef R. Bencsik; Dengming Xiao; Nicholas C. Kallan; Stephen Schlachter; Ian S. Mitchell; Keith L. Spencer; Anna L. Banka; Eli M. Wallace; Susan L. Gloor; Matthew Martinson; Richard D. Woessner; Guy Vigers; Barbara J. Brandhuber; Jun Liang; Brian S. Safina; Jun Li; Birong Zhang; Christine Chabot; Steven Do; Leslie Lee; Jason Oeh; Deepak Sampath; Brian Lee; Kui Lin; Bianca M. Liederer; Nicholas J. Skelton
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Cross-neutralization of influenza A viruses mediated by a single antibody loop
Nature, ISSN: 00280836 14764687
Damian C. Ekiert; Arun K. Kashyap; John Steel; Adam Rubrum; Gira Bhabha; Reza Khayat; Jeong Hyun Lee; Michael Dillon; Ryann E. O'Neil; Aleksandr M. Faynboym; Michael Horowitz; Lawrence Horowitz; Andrew B. Ward; Peter Palese; Richard Webby; Richard A. Lerner; Ramesh R. Bhatt; Ian A. Wilson
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The design and identification of brain penetrant inhibitors of phosphoinositide 3-kinase α
Journal of Medicinal Chemistry, ISSN: 00222623 15204804
Timothy P. Heffron; Laurent Salphati; Bruno Alicke; Jonathan Cheong; Jennafer Dotson; Kyle A. Edgar; Richard Goldsmith; Stephen Gould; Leslie Lee; John Lesnick; Lewis; Chudi O. Ndubaku; Jim Nonomiya; Alan G. Olivero; Jodie Pang; Emile G. Plise; Steve Sideris; Sean Trapp; Jeffery J. Wallin; Lan Wang; Xiaolin Zhang
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Discovery and preclinical pharmacology of a selective ATP-competitive Akt inhibitor (GDC-0068) for the treatment of human tumors
Journal of Medicinal Chemistry, ISSN: 00222623 15204804
James F. Blake; Rui Xu; Josef R. Bencsik; Dengming Xiao; Nicholas C. Kallan; Stephen Schlachter; Ian S. Mitchell; Keith L. Spencer; Anna L. Banka; Eli M. Wallace; Susan L. Gloor; Matthew Martinson; Richard D. Woessner; Guy Vigers; Barbara J. Brandhuber; Jun Liang; Brian S. Safina; Jun Li; Birong Zhang; Christine Chabot; Steven Do; Leslie Lee; Jason Oeh; Deepak Sampath; Brian B. Lee; Kui Lin; Bianca M. Liederer; Nicholas J. Skelton
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Spatially coordinated kinase signaling regulates local axon degeneration
Journal of Neuroscience, ISSN: 02706474 15292401
Mark Chen; Janice Maloney; Dara Y. Kallop; Jasvinder K. Atwal; Stephen Tam; Kristin Baer; Holger Kissel; Joshua S. Kaminker; Joe Lewcock; Robby M. Weimer; Ryan J. Watts
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Loss of the tumor suppressor BAP1 causes myeloid transformation
Science, ISSN: 10959203 00368075
Anwesha Dey; Dhaya Seshasayee; Rajkumar Noubade; French; Jinfeng Liu; Mira S. Chaurushiya; Donald S. Kirkpatrick; Victoria Pham; Jennie R. Lill; Corey Bakalarski; Jiansheng Wu; Lilian Phu; Paula Katavolos; Lindsay M. LaFave; Omar Abdel-Wahab; Zora Modrusan; Somasekar Seshagiri; Ken Dong; Zhonghua Lin; Mercedesz Balazs; Rowena Suriben; Kim Newton; Sarah G. Hymowitz; Guillermo Garcia-Manero; Flavius Martin; Ross L. Levine; Vishva M. Dixit
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Effectiveness of first-line management strategies for stage I follicular lymphoma: Analysis of the National Lymphocare Study
Journal of Clinical Oncology, ISSN: 0732183X 15277755
Jonathan W. Friedberg; Michelle Byrtek; Brian K. Link; Christopher R. Flowers; Taylor; John Hainsworth; James R. Cerhan; Zelenetz; Jamie Hirata; Thomas P. Miller
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Childhood disorders of the synapse: Challenges and opportunities
Science Translational Medicine, ISSN: 19466234 19466242
Virginia Hughes; Morgan Sheng; Huda Y. Zoghbi
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Impact of hemodialysis catheter dysfunction on dialysis and other medical services: An observational cohort study
International Journal of Nephrology, ISSN: 2090214X 20902158
Robert I. Griffiths; Britt B. Newsome; Grace Leung; Geoffrey A. Block; Robert J. Herbert; Mark Danese
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Pharmacokinetics and Biodistribution of a Human Monoclonal Antibody to Oxidized LDL in Cynomolgus Monkey Using PET Imaging
PLoS ONE, ISSN: 19326203
Amrita Kamath; Simon P. Williams; Sherron Bullens; Kyra J. Cowan; Yvonne Stenberg; Simon R. Cherry; Stephen Rendig; David L. Kukis; Chris Griesemer; Lisa A. Damico; Bunting
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Validity of cost and utility results?
PharmacoEconomics, ISSN: 11707690 11792027
Alex Diamantopoulos; Laura Sawyer; Sarika Ogale; Fred Dejonckheere
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Ras inhibition via direct Ras binding - Is there a path forward?
Bioorganic and Medicinal Chemistry Letters, ISSN: 14643405 0960894X
Weiru Wang; Guowei Fang; Joachim Rudolph
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RPN-6 determines C. elegans longevity under proteotoxic stress conditions
Nature, ISSN: 00280836 14764687
David Vilchez; Ianessa Morantte; Zheng Liu; Peter M. Douglas; Carsten Merkwirth; Ana P. C. Rodrigues; Gerard Manning; Andrew Dillin
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Potent and highly selective benzimidazole inhibitors of PI3-kinase delta
Journal of Medicinal Chemistry, ISSN: 00222623 15204804
Jeremy Murray; Zachary K. Sweeney; Bryan K. Chan; Mercedesz Balazs; Erin K. Bradley; Georgette M. Castanedo; Christine Chabot; David Chantry; Michael Flagella; David M. Goldstein; Rama Kondru; John Lesnick; Jun Li; Matthew C. Lucas; Jim Nonomiya; Jodie Pang; Stephen Price; Laurent Salphati; Brian S. Safina; Pascal P. A. Savy; Eileen Seward; Ultsch; Daniel P. Sutherlin
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A phase II study of trastuzumab emtansine in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer who were previously treated with trastuzumab, lapatinib, an anthracycline, a taxane, and capecitabine
Journal of Clinical Oncology, ISSN: 0732183X 15277755
Ian E. Krop; Patricia M. LoRusso; Kathy Miller; Shanu Modi; Denise A. Yardley; Gladys Rodriguez; Ellie Guardino; Michael W. Lu; Maoxia Zheng; Sandhya Girish; Lukas Amler; Eric P. Winer; Hope S. Rugo
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Dr. Sekulic and colleagues reply
New England Journal of Medicine, ISSN: 15334406 00284793
Aleksandar Sekulic; Josina C. Reddy; Axel Hauschild
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Internalization and endosomal degradation of receptor-bound antigens regulate the efficiency of cross presentation by human dendritic cells
Blood, ISSN: 15280020 00064971
Bithi Chatterjee; Anna Smed-Sörensen; Lillian Cohn; Cecile Chalouni; Richard L. Vandlen; Byoung-Chul Lee; Jenifer Widger; Tibor Keler; Lélia Delamarre; Ira Mellman
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Structural transitions of transmembrane helix 6 in the formation of Metarhodopsin i
Journal of Physical Chemistry B, ISSN: 15205207 15206106
Markus Eilers; Joseph A. Goncalves; Shivani Ahuja; Colleen Kirkup; Amiram Hirshfeld; Carlos Simmerling; Philip J. Reeves; Mordechai Sheves; Steven O. Smith
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High-content live-cell imaging assay used to establish mechanism of trastuzumab emtansine (T-DM1)-mediated inhibition of platelet production
Blood, ISSN: 15280020 00064971
Jonathan N. Thon; Matthew T. Devine; Antonija Jurak Begonja; Jay Tibbitts; Joseph E. Italiano Jr.
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Binding mechanism of metalṡNTP substrates and stringent-response alarmones to bacterial DnaG-type primases
Structure, ISSN: 18784186 09692126
Richard U. Rymer; Francisco A. Solorio; Ashley K. Tehranchi; Clement Chu; Jacob E. Corn; James L. Keck; Jue D. Wang; James M. Berger
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FAM83A confers EGFR-TKI resistance in breast cancer cells and in mice
Journal of Clinical Investigation, ISSN: 00219738 15588238
Sunyoung Lee; Roland Meier; Saori Furuta; Marc E. Lenburg; Paraic A. Kenny; Ren Xu; Mina J. Bissell
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Molecular basis for negative regulation of the glucagon receptor
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424 10916490
Christopher M. Koth; Jeremy Murray; Susmith Mukund; Azadeh Madjidi; Alexandra Minn; Holly J. Clarke; Wong; Vicki Chiang; Luis; Alberto Estevez; Jesus Rondon; Yingnan Zhang; Isidro Hötzel; Bernard B. Allan
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Intracellular VEGF regulates the balance between osteoblast and adipocyte differentiation
Journal of Clinical Investigation, ISSN: 00219738 15588238
Yanqiu Liu; Agnes D. Berendsen; Shidong Jia; Sutada Lotinun; Roland Baron; Napoleone Ferrara; Bjorn R. Olsen
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