Scientists / Publications

Publications

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DISPLAYING 7351 - 7400 OF 15217 RESULTS

Utilizing design of experiments to characterize assay robustness
Bioanalysis, ISSN: 17576180 17576199
Kyra J. Cowan; Erickson; Brian Sue; Reginald Delarosa; Bert Gunter; Daniel A. Coleman; Houston N. Gilbert; An Song; Saloumeh Kadkhodayan Fischer
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A generic HPLC/UV platform method for cleaning verification
American Pharmaceutical Review, ISSN: 10998012
Michael W. Dong; Eileen X. Zhao; Derrick T. Yazzie; Christine Gu; Jackson D. Pellett
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Evaluating the Impact of Patient Recruitment and Retention Practices
Drug Information Journal, ISSN: 00928615
Mary Jo Lamberti; Adam Mathias; Jane E. Myles; Deborah Howe; Ken Getz
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Pre-use/post-sterilization integrity testing of sterilizing grade filters
PDA Journal of Pharmaceutical Science and Technology, ISSN: 10797440 19482124
Karen Bartel; Harold S. Baseman; Gabriele Gori; Richard V. Levy; Hemisha Ly; Maik W. Jornitz; Russell Madsen; Michiel Rook; Sue Schniepp
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QbD for biologics
BioProcess International, ISSN: 15426319
Steven Kozlowski; Wassim Nashabeh; Mark Schenerman; Howard Anderson; Ilse Blumentals; Kowid Ho; Rohin Mahtre; Barbara Rellahan; Victor Vinci; Lorna McLeod
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Subcutaneous versus intravenous administration of (neo)adjuvant trastuzumab in patients with HER2-positive, clinical stage I-III breast cancer (HannaH study): A phase 3, open-label, multicentre, randomised trial
The Lancet Oncology, ISSN: 14702045 14745488
Gustavo Ismael; Roberto Hegg; Susanne Muehlbauer; Dominik Heinzmann; Bert L. Lum; Sung-Bae Kim; Tadeusz Pienkowski; Mikhail Lichinitser; Vladimir Semiglazov; Melichar; Christian Jackisch
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Safety and biodistribution of an equine infectious anemia virus-based gene therapy, retinostat®, for age-related macular degeneration
Human Gene Therapy, ISSN: 10430342 15577422
Katie Binley; Peter S. Widdowson; Michelle Kelleher; Jackie De Belin; Julie Loader; Georgina Ferrige; Marie Carlucci; Margaret Esapa; Daniel Chipchase; Diana Angell-Manning; Scott Ellis; Kyriacos Mitrophanous; James Miskin; Vlad Bantseev; Michael Nork; Paul Miller; Stuart Naylor
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Probing of C-terminal lysine variation in a recombinant monoclonal antibody production using Chinese hamster ovary cells with chemically defined media
Biotechnology and Bioengineering, ISSN: 00063592 10970290
Jun Luo; Jian Zhang; Diya Ren; Wen-Lin Tsai; Feng Li; Ashraf Amanullah; Terry Hudson
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2012 White paper on recent issues in bioanalysis and alignment of multiple guidelines
Bioanalysis, ISSN: 17576180 17576199
Binodh DeSilva; Fabio Garofolo; Mario Rocci; Suzanne Martinez; Isabelle Dumont; France Landry; Catherine Dicaire; Gabriella Szekely-Klepser; Russell Weiner; Mark Arnold; Surendra Bansal; Kevin Bateman; Ronald Bauer; Brian Booth; Scott Davis; Sherri Dudal; Dominique Gouty; John Grundy; Sam Haidar; Roger Hayes; Mohammed Jemal; Surinder Kaur; Marian Kelley; Magnus Knutsson; Olivier Le Blaye; Jean W. Lee; Steve Lowes; Mark Ma; Toshinari Mitsuoka; João Tavares Neto; Robert Nicholson; Eric Ormsby; Jeff M. Sailstad; Lauren Stevenson; Daniel Tang; Jan Welink; Viswanathan; Laixin Wang; Eric Woolf; Eric Yang
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The assay design used for measurement of therapeutic antibody concentrations can affect pharmacokinetic parameters: Case studies
mAbs, ISSN: 19420862 19420870
Saloumeh Kadkhodayan Fischer; Yang; Banmeet S. Anand; Kyra J. Cowan; Robert Hendricks; Jing Li; Nakamura; An Song
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Physiochemical and biochemical factors influencing the pharmacokinetics of antibody therapeutics
AAPS Journal, ISSN: 15507416
Daniela Bumbaca; C. Andrew Boswell; Fielder; Leslie A. Khawli
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Long-term effects of ranibizumab on diabetic retinopathy severity and progression
Archives of Ophthalmology, ISSN: 00039950 15383601
Michael S. Ip; Amitha Domalpally; J. Jill Hopkins; Pamela Wong; Jason S. Ehrlich
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Neuropilin-2 expression in cancer
Histopathology, ISSN: 03090167 13652559
Adrian M. Jubb; Susan Sa; Navneet Ratti; Laura A. Strickland; Maike Schmidt; Christopher Callahan; Koeppen
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Heritability and genome-wide association study to assess genetic differences between advanced age-related macular degeneration subtypes
Ophthalmology, ISSN: 01616420 15494713
Lucia Sobrin; Stephan Ripke; Yi Yu; Jesen Fagerness; Tushar Bhangale; Perciliz L. Tan; Eric H. Souied; Gabriëlle H.S. Buitendijk; Joanna E. Merriam; Andrea J. Richardson; Soumya Raychaudhuri; Robyn Reynolds; Kimberly A. Chin; Aaron Y. Lee; Nicolas Leveziel; Donald J. Zack; Peter A. Campochiaro; R. Theodore Smith; Gaetano R. Barile; Ruth E. Hogg; Usha Chakravarthy; Timothy W. Behrens; André G. Uitterlinden; Cornelia M. Van Duijn; Johannes R. Vingerling; Milam A. Brantley Jr.; Paul N. Baird; Caroline C.W. Klaver; Rando Allikmets; Nicholas Katsanis; Robert R. Graham; John P.A. Ioannidis; Mark J. Daly; Johanna M. Seddon
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Activation of the alternative complement pathway in vitreous is controlled by genetics in age-related macular degeneration
Investigative Ophthalmology and Visual Science, ISSN: 01460404 15525783
Kelly M. Loyet; Laura DeForge; Kenneth J. Katschke Jr.; Laurie Diehl; Robert R. Graham; Lily Pao; Lizette Sturgeon; Sock-Cheng Lewin-Koh; Joe G. Hollyfield; Menno Van Lookeren Campagne
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Preclinical assessment of the absorption and disposition of the phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor GDC-0980 and prediction of its pharmacokinetics and efficacy in human
Drug Metabolism and Disposition, ISSN: 00909556 1521009X
Laurent Salphati; Jodie Pang; Emile G. Plise; Leslie Lee; Alan G. Olivero; Wei Wei Prior; Deepak Sampath; Susan C. Wong; Xiaolin Zhang
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Risk factors for rate of decline in FEV1 in adults with cystic fibrosis
Journal of Cystic Fibrosis, ISSN: 15691993 18735010
Michael W. Konstan; Wagener; Donald R. VanDevanter; David J. Pasta; Ashley Yegin; Lawrence Rasouliyan; Morgan
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Culturing pyramidal neurons from the early postnatal mouse hippocampus and cortex
Nature Protocols, ISSN: 17542189 17502799
Gerard M. J. Beaudoin III; Seung-Hye Lee; Dipika Singh; Yang Yuan; Yu-Gie Ng; Louis F. Reichardt; Jyothi Arikkath
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The inhibitor of apoptosis (IAP) proteins are critical regulators of signaling pathways and targets for anti-cancer therapy
Experimental Oncology, ISSN: 18129269
Maria Cristina De Almagro; Domagoj Vucic
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Differential effects of predosing on tumor and tissue uptake of an 111in-labeled anti-TENB2 antibody-drug conjugate
Journal of Nuclear Medicine, ISSN: 01615505
C. Andrew Boswell; Eduardo E. Mundo; Crystal Zhang; Shannon Stainton; Shang-Fan Yu; Jennifer A. Lacap; Mao; Katherine R. Kozak; Aimee Fourie-O'Donohue; Paul G. Polakis; Leslie A. Khawli; Kedan Lin
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Compartmental tissue distribution of antibody therapeutics: Experimental approaches and interpretations
AAPS Journal, ISSN: 15507416
C. Andrew Boswell; Daniela Bumbaca; Fielder; Leslie A. Khawli
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Diagnosis and management of childhood obstructive sleep apnea syndrome
Pediatrics, ISSN: 00314005 10984275
Carole L. Marcus; Lee Jay Brooks; Sally Davidson Ward; Kari A. Draper; David Gozal; Ann Carol Halbower; Jacqueline Jones; Christopher Lehmann; Michael S. Schechter; Stephen Howard Sheldon; Richard N. Shiffman; Karen Spruyt
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Diagnosis and management of childhood obstructive sleep apnea syndrome
Pediatrics, ISSN: 00314005 10984275
Carole L. Marcus; Lee Jay Brooks; Kari A. Draper; David Gozal; Ann Carol Halbower; Jacqueline Jones; Michael S. Schechter; Stephen Howard Sheldon; Karen Spruyt; Sally Davidson Ward; Christopher Lehmann; Richard N. Shiffman
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Drug interaction potential of trastuzumab emtansine (T-DM1) combined with pertuzumab in patients with HER2-positive metastatic breast cancer
Current Drug Metabolism, ISSN: 13892002 18755453
Dan Lu; Howard A. Burris; Wang; E. Claire Dees; Javier Cortés; Amita Joshi; Manish Gupta; Joo-Hee Yi; Yu-Waye Chu; Ted Shih; Liang Fang; Sandhya Girish
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Dyslipidemia and changes in lipid profiles associated with rheumatoid arthritis and initiation of anti-tumor necrosis factor therapy
Arthritis Care and Research, ISSN: 2151464X 21514658
Jeffrey R. Curtis; Ani John; Onur Baser
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Tissue distribution studies of protein therapeutics using molecular probes: Molecular imaging
AAPS Journal, ISSN: 15507416
Simon P. Williams
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A role for Th17 cells in the regulation of tertiary lymphoid follicles
European Journal of Immunology, ISSN: 00142980 15214141
Jane L. Grogan; Wenjun Ouyang
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Psychometric evaluation of the cystic fibrosis questionnaire-revised in a national sample
Quality of Life Research, ISSN: 09629343
Alexandra L. Quittner; Gregory S. Sawicki; Ann McMullen; Lawrence Rasouliyan; David J. Pasta; Ashley Yegin; Michael W. Konstan
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Pharmacokinetic considerations for antibody drug conjugates
Pharmaceutical Research, ISSN: 07248741 1573904X
Kedan Lin; Jay Tibbitts
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Catabolic fate and pharmacokinetic characterization of trastuzumab emtansine (T-DM1): An Emphasis on preclinical and clinical catabolism
Current Drug Metabolism, ISSN: 13892002 18755453
Shen; Daniela Bumbaca; Ola M. Saad; Qin Yue; Cinthia V Pastuskovas; S. Cyrus Khojasteh; Jay Tibbitts; Surinder Kaur; Wang; Yu-Waye Chu; Patricia M. LoRusso; Sandhya Girish
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Anti-neuropilin-1 (MNRP1685A): Unexpected pharmacokinetic differences across species, from preclinical models to humans
Pharmaceutical Research, ISSN: 07248741 1573904X
Yan Xin; Shuang Bai; Lisa A. Damico; Denise Jin; Wei-Ching Liang; Yan Wu; Frank-Peter Theil; Amita Joshi; Yanmei Lu; John Lowe; Mauricio Maia; Rainer Brachmann; Hong Xiang
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Sequencing and analysis of a South Asian-Indian personal genome
BMC Genomics, ISSN: 14712164
Ravi Gupta; Aakrosh Ratan; Changanamkandath Rajesh; Rong Chen; Hie Lim Kim; Richard Burhans; Webb Miller; Sam Santhosh; Ramana V. Davuluri; Atul J. Butte; Stephan C. Schuster; Somasekar Seshagiri; George Thomas
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Recurrent R-spondin fusions in colon cancer
Nature, ISSN: 00280836 14764687
Somasekar Seshagiri; Eric Stawiski; Durinck; Zora Modrusan; Elaine E. Storm; Caitlin B. Conboy; Subhra Chaudhuri; Yinghui Guan; Vasantharajan Janakiraman; Bijay S. Jaiswal; Joseph Guillory; Connie Ha; Gerrit J. P. Dijkgraaf; Stinson; Florian Gnad; Melanie A. Huntley; Jeremiah D. Degenhardt; Matthias Peter; Richard Bourgon; Weiru Wang; Koeppen; Robert Gentleman; Timothy Starr; Zemin Zhang; David A. Largaespada; Thomas D Wu; Frederic J. De Sauvage
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Tumour-secreted miR-9 promotes endothelial cell migration and angiogenesis by activating the JAK-STAT pathway
EMBO Journal, ISSN: 02614189 14602075
Guanglei Zhuang; Xiumin Wu; Zhaoshi Jiang; Ian Kasman; Jenny Yao; Yinghui Guan; Jason Oeh; Zora Modrusan; Carlos Bais; Deepak Sampath; Napoleone Ferrara
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Transforming quality of care and improving outcomes after acute MI: Lessons from the national registry of myocardial infarction
JAMA - Journal of the American Medical Association, ISSN: 15383598 00987484
William J. French; Vanessa S. Reddy; Hal V. Barron
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Profiling antibody drug conjugate positional isomers: A system-of-equations approach
Analytical Chemistry, ISSN: 15206882 00032700
Lan N. Le; Jamie M. R. Moore; Jun Ouyang; Xiaoying Chen; Mary D. H. Nguyen; William J. Galush
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Identification and characterization of buried unpaired cysteines in a recombinant monoclonal igg1 antibody
Analytical Chemistry, ISSN: 00032700 15206882
Taylor Zhang; Jennifer Zhang; Daniel Hewitt; Ben Tran; Xiaoying Gao; Zhihua Julia Qiu; Max L. Tejada; Hélène Gazzano-Santoro; Kao
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Evaluation of an accurate mass approach for the simultaneous detection of drug and metabolite distributions via whole-body mass spectrometric imaging
Analytical Chemistry, ISSN: 00032700 15206882
Sheerin Shahidi-Latham; Sucharita M. Dutta; Maria C. Prieto Conaway; Patrick J. Rudewicz
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Reversible modification of adenomatous polyposis coli (APC) with K63-linked polyubiquitin regulates the assembly and activity of the β-catenin destruction complex
Journal of Biological Chemistry, ISSN: 00219258 1083351X
Hoanh Tran; Paul G. Polakis
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Step-economic synthesis of (+)-crocacin C: A concise crotylboronation/[3,3] -sigmatropic rearrangement approach
Journal of Organic Chemistry, ISSN: 00223263 15206904
Adele E. Pasqua; Frank D. Ferrari; Chris Hamman; Yanzhou Liu; James J. Crawford; Rodolfo Marquez
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Balancing continuous and categorical baseline covariates in sequential clinical trials using the area between empirical cumulative distribution functions
Statistics in Medicine, ISSN: 02776715 10970258
Yunzhi Lin; Zheng Su
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Pari passu dimers of dimers
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424 10916490
Mark X. Sliwkowski
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Cardiovascular and systemic microvascular-effects of anti-vascular endothelial growth factor therapy for cancer
Journal of the American College of Cardiology, ISSN: 07351097 15583597
J. Todd Belcik; Yue Qi; Beat A. Kaufmann; Aris Xie; Sherron Bullens; Terry K. Morgan; Susan P. Bagby; Ganesh Kolumam; Joe Kowalski; Jon A. Oyer; Bunting; Jonathan R. Lindner
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Functional significance of isoform diversification in the protocadherin gamma gene cluster
Neuron, ISSN: 08966273 10974199
Weisheng V. Chen; Francisco J. Alvarez; Julie L. Lefebvre; Brad A. Friedman; Chiamaka Nwakeze; Eric Geiman; Courtney Smith; Chan Aye Thu; Juan Carlos Tapia; Bosiljka Tasic; Joshua R. Sanes; Tom Maniatis
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Quantification and characterization of micrometer and submicrometer subvisible particles in protein therapeutics by use of a suspended microchannel resonator
Analytical Chemistry, ISSN: 00032700 15206882
Ankit Patel; Doris Lau; Jun Liu
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Patient out-of-pocket payments for oral oncolytics: Results from a 2009 us claims data analysis
American Journal of Managed Care, ISSN: 10880224
Martin L. Raborn; Elise M. Pelletier; Daniel B. Smith; Carolina Reyes
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Function, targets, and evolution of Caenorhabditis elegans piRNAs
Science, ISSN: 10959203 00368075
Marloes P. Bagijn; Leonard D. Goldstein; Alexandra Sapetschnig; Eva-Maria Weick; Samir Bouasker; Nicolas J. Lehrbach; Martin J. Simard; Eric A. Miska
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A mutation in APP protects against Alzheimer‘s disease and age-related cognitive decline
Nature, ISSN: 00280836
Thorlakur Jonsson; Jasvinder K. Atwal; Stacy Steinberg; Jon Snaedal; Palmi V. Jonsson; Sigurbjorn Bjornsson; Hreinn Stefansson; Patrick Sulem; Daniel Gudbjartsson; Janice Maloney; Kwame Hoyte; Amy Gustafson; Yichin Liu; Yanmei Lu; Tushar Bhangale; Robert R. Graham; Johanna Huttenlocher; Gyda Bjornsdottir; Ole A. Andreassen; Erik G. Jönsson; Aarno Palotie; Timothy W. Behrens; Olafur T. Magnusson; Augustine Kong; Unnur Thorsteinsdottir; Ryan J. Watts; Kari Stefansson
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Nanolitre-scale crystallization using acoustic liquid-transfer technology
Acta Crystallographica Section D: Biological Crystallography, ISSN: 09074449 13990047
Armando G. Villasẽor; April Wong; Ada Shao; Ankur Garg; Timothy J. Donohue; Andreas Kuglstatter; Seth F. Harris
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Drug absorption interactions between oral targeted anticancer agents and PPIs: Is pH-dependent solubility the achilles heel of targeted therapy
Clinical Pharmacology and Therapeutics, ISSN: 00099236 15326535
Nageshwar Budha; Adam Frymoyer; Gillian S. Smelick; Jin Y. Jin; Marc R. Yago; Mark J. Dresser; Scott N. Holden; Leslie Z. Benet; Joseph A. Ware
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