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Publications

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DISPLAYING 8551 - 8600 OF 15217 RESULTS

Preface
Formulation and Process Development Strategies for Manufacturing Biopharmaceuticals,
Feroz Jameel; Susan Hershenson
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Construction, MD simulation, and hydrodynamic validation of an all-atom model of a monoclonal IgG antibody
Biophysical Journal, ISSN: 15420086 00063495
J. Paul Brandt; Thomas W. Patapoff; Sergio R. Aragon
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Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella
Journal of Experimental Medicine, ISSN: 15409538 00221007
Petr Broz; Kim Newton; Lamkanfi; Sanjeev Mariathasan; Vishva M. Dixit; Denise M. Monack
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Pseudo-active sites of protease domains: HGF/Met and Sonic hedgehog signaling in cancer
Biological Chemistry, ISSN: 14316730 14374315
Henry R. Maun; Daniel Kirchhofer; Lazarus
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Effect of trastuzumab on health-related quality of life in patients with HER2-positive metastatic breast cancer: Data from three clinical trials
Clinical Breast Cancer, ISSN: 15268209
Hope S. Rugo; Melissa Brammer; Fan Zhang; Deepa Lalla
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Subset analysis of patients experiencing clinical events of a potentially immunogenic nature in the pivotal clinical trials of tocilizumab for rheumatoid arthritis: Evaluation of an antidrug antibody ELISA using clinical adverse event-driven immunogenicity testing
Clinical Therapeutics, ISSN: 01492918 1879114X
Kay Stubenrauch; Uwe Wessels; Herbert Birnboeck; Francisco Ramirez; Angelika Jahreis; Julia Schleypen
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Cyclic amide bioisosterism: Strategic application to the design and synthesis of HCV NS5B polymerase inhibitors
Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X
Hanbiao Yang; Robert T. Hendricks; Nidhi Arora; Dov Nitzan; Calvin Yee; Matthew C. Lucas; Yanli Yang; Amy Fung; Sonal Rajyaguru; Seth F. Harris; Vincent J.P. Leveque; Julie Qi Hang; Sophie Le Pogam; Deborah Reuter; Gisele A. Tavares
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High-yield expression of human vascular endothelial growth factor VEGF 165 in Escherichia coli and purification for therapeutic applications
Protein Expression and Purification, ISSN: 10465928
Shelly A. Pizarro; Jane Gunson; Field; Rachel Dinges; Stefanie Khoo; Milind Dalal; Michael Lee; Kimberly A. Kaleas; Kathryn Moiseff; Susan Garnick; Dorothea Reilly; Mike Laird; Charles H. Schmelzer
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Distal regions of the human IFNG locus direct cell type-specific expression
Journal of Immunology, ISSN: 00221767 15506606
Patrick L. Collins; Shaojing Chang; Melodie Henderson; Mohammed Soutto; Georgia M. Davis; Allyson G. McLoed; Michael J. Townsend; Laurie H. Glimcher; Douglas P. Mortlock; Aune
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Tumor associated endothelial expression of B7-H3 predicts survival in ovarian carcinomas
Modern Pathology, ISSN: 08933952 15300285
Xingxing Zang; Peggy S. Sullivan; Robert A. Soslow; Rebecca Waitz; Victor E. Reuter; Andrew Wilton; Howard T. Thaler; Manonmani Arul; Susan F. Slovin; Joyce Wei; David R. Spriggs; Jakob Dupont; James P. Allison
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K11-linked polyubiquitination in cell cycle control revealed by a K11 linkage-specific antibody
Molecular Cell, ISSN: 10972765
Marissa L. Matsumoto; Katherine E. Wickliffe; Ken Dong; Christine Yu; Ivan Bosanac; Daisy J. Bustos; Lilian Phu; Donald S. Kirkpatrick; Sarah G. Hymowitz; Michael Rape; Robert F. Kelley; Vishva M. Dixit
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A chemosensitization screen identifies TP53RK, a kinase that restrains apoptosis after mitotic stress
Cancer Research, ISSN: 00085472 15387445
David Peterson; James Lee; Xingye Lei; William F. Forrest; David P. Davis; Peter K Jackson; Lisa D. Belmont
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The Type 1 Diabetes PhysioLab® Platform: A validated physiologically based mathematical model of pathogenesis in the non-obese diabetic mouse
Clinical and Experimental Immunology, ISSN: 00099104 13652249
Shoda; Kreuwel; Kapil Gadkar; Zheng; Whiting; Mark Atkinson; Jeffrey A. Bluestone; Mathis; Young; Ramanujan
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The lytic transcriptome of Kaposi's sarcoma-associated herpesvirus reveals extensive transcription of noncoding regions, including regions antisense to important genes
Journal of Virology, ISSN: 0022538X 10985514
Sanjay Chandriani; Yiyang Xu; Don Ganem
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Neural RNA-Binding Protein Musashi1 Controls Midline Crossing of Precerebellar Neurons through Posttranscriptional Regulation of Robo3/Rig-1 Expression
Neuron, ISSN: 08966273
Ken-ichiro Kuwako; Kyoko Kakumoto; Takao Imai; Mana Igarashi; Takao Hamakubo; Shin-ichi Sakakibara; Marc Tessier-Lavigne; Hirotaka James Okano; Hideyuki Okano
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A plate-based assay to measure cellular ERK substrate phosphorylation: Utility for drug discovery of the MAPK-signaling cascade
Assay and Drug Development Technologies, ISSN: 1540658X
Sreemathy Ramaswamy; Ivana Yen; Steve Sideris; Shiva Malek; Christopher E. Heise
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Enhancement of DNA uptake in FUT8-deleted CHO cells for transient production of afucosylated antibodies
Biotechnology and Bioengineering, ISSN: 10970290 00063592
Athena W. Wong; Tomasz K. Baginski; Dorothea Reilly
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Effects of anti-VEGF treatment duration on tumor growth, tumor regrowth, and treatment efficacy
Clinical Cancer Research, ISSN: 10780432 15573265
Anil Bagri; Berry; Bert Gunter; Mallika Singh; Ian Kasman; Lisa A. Damico; Hong Xiang; Maike Schmidt; Fuh; Beth A Hollister; Oliver Rosen; Greg D. Plowman
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Deletion of the RNA-binding proteins ZFP36L1 and ZFP36L2 leads to perturbed thymic development and T lymphoblastic leukemia
Nature Immunology, ISSN: 15292908 15292916
Daniel J. Hodson; Michelle L. Janas; Alison Galloway; Sarah E. Bell; Simon Andrews; Cheuk M. Li; Richard Pannell; Christian W. Siebel; H. Robson MacDonald; Kim De Keersmaecker; Adolfo A. Ferrando; Gerald Grutz; Martin Turner
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Avoiding infusion therapy prime benefit of new MS drug: The search for an acceptable oral MS drug may be over if fingolimod (Gilenia) survives an FDA review this fall
Managed Care, ISSN: 10623388
Thomas Morrow
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Vive la science! Vive le hérisson!
EMBO Reports, ISSN: 1469221X 14693178
Jeremy Reiter; Frederic J. De Sauvage
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Vertebrate Hedgehog signaling: Cilia rule
BMC Biology, ISSN: 17417007
Christopher W. Wilson; Didier Y. R. Stainier
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Managing Successful Product Portfolio Creation and R&D Pipelines
Pharmaceutical and Biomedical Project Management in a Changing Global Environment,
Sue E. Steven
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Persistence of coordinated long-term potentiation and dendritic spine enlargement at mature hippocampal CA1 synapses requires N-cadherin
Journal of Neuroscience, ISSN: 02706474 15292401
Ozlem Bozdagi; Xiaobin Wang; Jessica S. Nikitczuk; Tonya R. Anderson; Erik B. Bloss; Glenn L. Radice; Qiang Zhou; Deanna L. Benson; George W. Huntley
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Preparation and separation of antimicrobial agents derived from capreomycin
Tetrahedron Letters, ISSN: 00404039
D. David Hennings; Daniel J. Watson; Joseph P. Lyssikatos; Andrew Allen
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The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424 10916490
Lee Honigberg; Ashley Smith; Mint Sirisawad; Erik Verner; David Loury; Betty Chang; Shyr Li; Zhengying Pan; Douglas H. Thamm; Richard A. Miller; Joseph J. Buggy
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Structure of cinaciguat (BAY 58-2667) bound to Nostoc H-NOX domain reveals insights into heme-mimetic activation of the soluble guanylyl cyclase
Journal of Biological Chemistry, ISSN: 00219258 1083351X
Faye Martin; Padmamalini Baskaran; Xiaolei Ma; Pete W. Dunten; Martina Schaefer; Johannes-Peter Stasch; Annie Beuve; Focco Van Den Akker
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IL-17RC is required for immune signaling via an extended SEF/IL-17R signaling domain in the cytoplasmic tail
Journal of Immunology, ISSN: 00221767 15506606
Allen W. Ho; Fang Shen; Heather R. Conti; Nayan Patel; Erin E. Childs; Alanna C. Peterson; Nydiaris Herna´ndez-Santos; Jay K. Kolls; Lawrence P. Kane; Wenjun Ouyang; Sarah L. Gaffen
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Predictive biomarkers of sensitivity to the phosphatidylinositol 3′ kinase inhibitor GDC-0941 in breast cancer preclinical models
Clinical Cancer Research, ISSN: 10780432 15573265
Carol O'Brien; Jeffery J. Wallin; Deepak Sampath; Debraj GuhaThakurta; Heidi Savage; Elizabeth A. Punnoose; Zhengyu Guan; Berry; Wei Wei Prior; Lukas Amler; Marcia Belvin; Lori S. Friedman; Lackner
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Rituximab versus cyclophosphamide for ANCA-associated vasculitis
New England Journal of Medicine, ISSN: 15334406 00284793
John H. Stone; Merkel; Spiera; Seo; Langford; Hoffman; Cees Kallenberg; St.clair; Anthony Turkiewicz; Tchao; Lisa Webber; Linna Ding; Lourdes P. Sejismundo; Kathleen Mieras; David Weitzenkamp; Iklé; Vicki Seyfert-Margolis; Mark Mueller; Paul Brunetta; Allen; Fervenza; Duvuru Geetha; Keogh; Kissin; Monach; Peikert; Stegeman; Steven R. Ytterberg; Specks
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Collaborative and specialized functions of Robo1 and Robo2 in spinal commissural axon guidance
Journal of Neuroscience, ISSN: 02706474 15292401
Alexander Jaworski; Hua Long; Marc Tessier-Lavigne
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Functionally defective germline variants of sialic acid acetylesterase in autoimmunity
Nature, ISSN: 00280836 14764687
Ira Surolia; Stephan P. Pirnie; Vasant Chellappa; Kendra N. Taylor; Annaiah Cariappa; Jesse Moya; Haoyuan Liu; Daphne W. Bell; David R. Driscoll; Sven Diederichs; Khaleda Haider; Ilka Netravali; Sheila Le; Roberto Elia; Ethan Dow; Annette T. Lee; Jan Freudenberg; Philip L. De Jager; Yves Chretien; Ajit Varki; Marcy E. MacDonald; Tammy Gillis; Timothy W. Behrens; Donald Bloch; Deborah Collier; Joshua Korzenik; Daniel K. Podolsky; David A. Hafler; Mandakolathur Murali; Bruce Sands; John H. Stone; Peter K. Gregersen; Shiv Pillai
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Development of a two-part strategy to identify a therapeutic human bispecific antibody that inhibits IgE receptor signaling
Journal of Biological Chemistry, ISSN: 00219258 1083351X
Janet Jackman; Yongmei Chen; Arthur Huang; Moffat; Justin M. Scheer; Leong; Wyne P. Lee; Juan Zhang; Navneet Sharma; Yanmei Lu; Suhasini Iyer; Robert L. Shields; Nancy Y. Chiang; Michele Bauer; Diana Jakubiak; Merone Roose-Girma; Richard L. Vandlen; Yansura; Yan Wu; Lawren C. Wu
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Response
Science, ISSN: 10959203 00368075
Levinson
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Prosthetic hand provides nearly normal function: It might seem to be straight out of science fiction, but there's solid science and engineering behind it
Managed Care, ISSN: 10623388
Thomas Morrow
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Unique challenges and opportunities for enabling and supporting preclinical and translational areas of biologic development in India - A perspective
American Pharmaceutical Outsourcing, ISSN: 15296318
Ashwin Datt; Sara Kenkare-Mitra
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US cost burden of ischemic stroke: A systematic literature review
American Journal of Managed Care, ISSN: 10880224
Bart M. Demaerschalk; Ha-Mill Hwang; Grace Leung
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Lymphotoxin-αβ heterotrimers are cleaved by metalloproteinases and contribute to synovitis in rheumatoid arthritis
Cytokine, ISSN: 10434666
Judy Young; Xin Yu; Kristen Wolslegel; Allen Nguyen; Catherine Kung; Eugene Y. Chiang; Ganesh Kolumam; Nathan Wei; Wai Lee T. Wong; Laura DeForge; Michael J. Townsend; Jane L. Grogan
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Rheumatoid arthritis risk allele PTPRC is also associated with response to anti-tumor necrosis factor α therapy
Arthritis and Rheumatism, ISSN: 00043591 15290131
Jing Cui; Saedis Saevarsdottir; Brian Thomson; Leonid Padyukov; Annette H. M. Van Der Helm-van Mil; Joanne Nititham; Laura B. Hughes; Niek De Vries; Soumya Raychaudhuri; Lars Alfredsson; Johan Askling; Wedren; Bo Ding; Candace Guiducci; Gert Jan Wolbink; J. Bart A. Crusius; Irene E. Van Der Horst-Bruinsma; Marieke Herenius; Michael E. Weinblatt; Nancy A. Shadick; Jane Worthington; Franak Batliwalla; Marlena Kern; Ann W. Morgan; Anthony G. Wilson; John D. Isaacs; Kimme Hyrich; Michael F. Seldin; Larry W. Moreland; Timothy W. Behrens; Allaart; Lindsey A. Criswell; Tom W. J. Huizinga; Paul P. Tak; S. Louis Bridges Jr.; Toes; Anne Barton; Lars Klareskog; Peter K. Gregersen; Elizabeth W. Karlson; Robert M. Plenge
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Response
Chest, ISSN: 19313543 00123692
Sarika Ogale; Todd A. Lee; Sean D. Sullivan
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Zinc Finger Nucleases as tools to understand and treat human diseases
BMC Medicine, ISSN: 17417015
David P. Davis; David Stokoe
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Reply to S.N. Wolff
Journal of Clinical Oncology, ISSN: 0732183X 15277755
Suman Bhattacharya; Gwendolyn Fyfe; Robert Gray; Daniel J. Sargent
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Year-to-year changes in lung function in individuals with cystic fibrosis
Journal of Cystic Fibrosis, ISSN: 15691993
Liou; Eric Elkin; David J. Pasta; Joan R. Jacobs; Michael W. Konstan; Morgan; Wagener
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Targeting the tumour vasculature: Insights from physiological angiogenesis
Nature Reviews Cancer, ISSN: 1474175X 14741768
Alicia S Chung; John Lee; Napoleone Ferrara
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Characterization of a monoclonal antibody cell culture production process using a quality by design approach
Molecular Biotechnology, ISSN: 10736085
Brian Horvath; Melissa Mun; Mike Laird
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The role of the hedgehog signaling pathway in the development of basal cell carcinoma and opportunities for treatment
Clinical Cancer Research, ISSN: 10780432 15573265
Ivor Caro; Low
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Cost analysis review of stroke centers, telestroke, and rt-PA
American Journal of Managed Care, ISSN: 10880224
Bart M. Demaerschalk; Ha-Mill Hwang; Grace Leung
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New neurons clear the path of astrocytic processes for their rapid migration in the adult brain
Neuron, ISSN: 08966273
Naoko Kaneko; Oscar Marín; Masato Koike; Yuki Hirota; Yasuo Uchiyama; Jane Y. Wu; Qiang Lu; Marc Tessier-Lavigne; Arturo Alvarez-Buylla; Hideyuki Okano; John L. R. Rubenstein; Kazunobu Sawamoto
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Neuropilin-1 promotes cirrhosis of the rodent and human liver by enhancing PDGF/TGF-β signaling in hepatic stellate cells
Journal of Clinical Investigation, ISSN: 00219738 15588238
Sheng Cao; Usman Yaqoob; Amitava Das; Uday Shergill; Kumaravelu Jagavelu; Robert C. Huebert; Chittaranjan Routray; Soha Abdelmoneim; Meher Vasdev; Edward Leof; Michael R. Charlton; Ryan J. Watts; Debabrata Mukhopadhyay; Vijay H. Shah
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Use of disposable reactors to generate inoculum cultures for E. coli production fermentations
Biotechnology Progress, ISSN: 87567938 15206033
Ekta Mahajan; Timothy Matthews; Ryan Hamilton; Mike Laird
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