Genentech: Publications

February 1, 2010

Targeting the tumor microenvironment with Src kinase inhibition

Clinical Cancer Research, ISSN: 10780432

Alicia S Chung; Napoleone Ferrara

February 1, 2010

Molecular predictors of 3D morphogenesis by breast cancer cell lines in 3D culture

PLoS Computational Biology, ISSN: 1553734X 15537358

Ju Han; Hang Chang; Orsi Giricz; Genee Y. Lee; Frederick L. Baehner; Joe W. Gray; Mina J. Bissell; Paraic A. Kenny; Bahram Parvin

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February 1, 2010

Bioavailability in healthy adults of efavirenz capsule contents mixed with a small amount of food

American Journal of Health-System Pharmacy, ISSN: 15352900 10792082

Sanjeev Kaul; Ping Ji; Michael W. Lu; Kim L. Nguyen; Tong Shangguan; Dennis Grasela

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February 1, 2010

Modular architecture of Munc13/calmodulin complexes: Dual regulation by Ca 2 and possible function in short-term synaptic plasticity

EMBO Journal, ISSN: 02614189 14602075

Fernando Rodríguez-Castãeda; Mitcheell Maestre-Martínez; Nicolas Coudevylle; Kalina Dimova; Harald Junge; Noa Lipstein; Donghan Lee; Stefan Becker; Nils Brose; Olaf Jahn; Teresa Carlomagno; Christian Griesinger

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February 1, 2010

Editorial overview

Current Opinion in Immunology, ISSN: 09527915

Ira Mellman; Peter Cresswell

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February 1, 2010

Outlier options: Consider simple parametric tests to find an outlier's significance

Quality Progress, ISSN: 0033524X

Julia E. Seaman; I. Elaine Allen

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February 1, 2010

Ixabepilone: Providing new hope for women with breast cancer after anthracycline and taxane failure

Clinical journal of oncology nursing, ISSN: 10921095 1538067X

Alisha Stein

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January 29, 2010

Understanding and mitigating conductivity transitions in weak cation exchange chromatography

Journal of Chromatography A, ISSN: 00219673

Jace Fogle; Jenny Hsiung

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January 25, 2010

Dynamics of the bacterial intermediate filament crescentin in vitroand in vivo

PLoS ONE, ISSN: 19326203

Osigwe Esue; Laura Rupprecht; Sean X. Sun; Denis Wirtz

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January 22, 2010

Autocrine VEGF Signaling Synergizes with EGFR in Tumor Cells to Promote Epithelial Cancer Development

Cell, ISSN: 00928674

Beate M. Lichtenberger; Poi Kiang Tan; Heide Niederleithner; Napoleone Ferrara; Peter Petzelbauer; Maria Sibilia

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January 19, 2010

Local Protease Signaling Contributes to Neural Tube Closure in the Mouse Embryo

Developmental Cell, ISSN: 15345807

Eric Camerer; Adrian Barker; Daniel N. Duong; Rajkumar Ganesan; Hiroshi Kataoka; Ivo Cornelissen; Molly R. Darragh; Arif Hussain; Yao-Wu Zheng; Yoga Srinivasan; Christopher Brown; Shan-Mei Xu; Jean B. Regard; Chen-Yong Lin; Charles S. Craik; Daniel Kirchhofer; Shaun R. Coughlin

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January 19, 2010

Stromal cell-derived factor-1/CXCL12 contributes to MMTV-Wnt1 tumor growth involving Gr1+CD11b+ cells

PLoS ONE, ISSN: 19326203

Bob Y. Liu; Soloviev; Peter Chang; John Lee; Xiaodong Huang; Cuiling Zhong; Napoleone Ferrara; Paul G. Polakis; Sakanaka

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January 19, 2010

β1 Integrin Establishes Endothelial Cell Polarity and Arteriolar Lumen Formation via a Par3-Dependent Mechanism

Developmental Cell, ISSN: 15345807

Ann C. Zovein; Alfonso Luque; Kirsten A. Turlo; Jennifer J. Hofmann; Kathleen M. Yee; Michael S. Becker; Reinhard Fässler; Ira Mellman; Timothy F. Lane; M. Luisa Iruela-Arispe

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January 19, 2010

Utilization of lysozyme charge ladders to examine the effects of protein surface charge distribution on binding affinity in ion exchange systems

Langmuir, ISSN: 07437463

Wai Keen Chung; Steven T. Evans; Alexander S. Freed; James J. Keba; Zachary C. Baer; Kaushal Rege; Steven M. Cramer

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January 18, 2010

Negative regulation of autoimmune demyelination by the inhibitory receptor CLM-1

Journal of Experimental Medicine, ISSN: 00221007 15409538

Hongkang Xi; Kenneth J. Katschke Jr.; Karim Y. Helmy; Paige A. Wark; Noelyn Kljavin; Hilary F. Clark; Jeffrey Eastham-Anderson; Theresa Shek; Merone Roose-Girma; Nico Ghilardi; Menno Van Lookeren Campagne

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January 15, 2010

Corrigendum to "GDC-0449-A potent inhibitor of the hedgehog pathway" [Bioorg. Med. Chem. Lett. 19 (2009) 5576] (DOI:10.1016/j.bmcl.2009.08.049)

Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X

Kirk D. Robarge; Shirley A. Brunton; Georgette M. Castanedo; Yong Cui; Dina; Richard Goldsmith; Stephen Gould; Oivin Guichert; Janet Gunzner; Jason S Halladay; Wei Jia; S. Cyrus Khojasteh; Michael F. T. Koehler; Karen Kotkow; Hank La; Rebecca L. LaLonde; Kevin Lau; Leslie Lee; Derek Marshall; James C. Marsters Jr.; Lesley J. Murray; Changgeng Qian; Lee L. Rubin; Laurent Salphati; Mark S. Stanley; John H.A. Stibbard; Daniel P. Sutherlin; Savita Ubhayakar; Shumei Wang; Susan C. Wong; Minli Xie

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January 15, 2010

Reversing HOXA9 oncogene activation by PI3K inhibition: Epigenetic mechanism and prognostic significance in human glioblastoma

Cancer Research, ISSN: 00085472 15387445

Bruno M. Costa; Justin S. Smith; Ying Chen; Justin Chen; Phillips; Kenneth D. Aldape; Giuseppe Zardo; Janice M. Nigro; C. David James; Jane Fridlyand; Rui M. Reis; Joseph F. Costello

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January 15, 2010

Cutting edge: Plasmacytoid dendritic cells induce IL-10 production in T cells via the Delta-like-4/Notch axis

Journal of Immunology, ISSN: 00221767 15506606

Nadine Kassner; Manuela Krueger; Hideo Yagita; Andrzej Dzionek; Andreas Hutloff; Richard Kroczek; Alexander Scheffold; Sascha Rutz

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January 11, 2010

Neuropilin-2 mediates VEGF-C-induced lymphatic sprouting together with VEGFR3

Journal of Cell Biology, ISSN: 00219525 00219525

Yunling Xu; Li Yuan; Judy Mak; Luc Pardanaud; Maresa Caunt; Ian Kasman; Bruno Larrivee; Raquel del Toro; Steven Suchting; Alexander Medvinsky; Jillian Silva; Jian Yang; Jean-Léon Thomas; Alexander W. Koch; Kari Alitalo; Anne Eichmann; Anil Bagri

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January 8, 2010

Four-component synthesis of fully substituted 1,2,4-triazoles

Angewandte Chemie - International Edition, ISSN: 14337851

Steven T. Staben; Nicole Blaquiere

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January 8, 2010

Industrial case study: Evaluation of a mixed-mode resin for selective capture of a human growth factor recombinantly expressed in E. coli

Journal of Chromatography A, ISSN: 00219673

Kimberly A. Kaleas; Charles H. Schmelzer; Shelly A. Pizarro

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January 7, 2010

Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival

Nature, ISSN: 00280836 14764687

Martin Schwickart; Xiaodong Huang; Jennie R. Lill; Jinfeng Liu; Ron Ferrando; French; Heather Maecker; Karen M. O'Rourke; J.Fernando Bazan; Jeffrey Eastham-Anderson; Peng Yue; David Dornan; David C.S. Huang; Vishva M. Dixit

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January 1, 2010

Pharmaceutical medical information contact centers: Results of three benchmarking surveys

Drug Information Journal, ISSN: 00928615

Pete Guillot; Stacey M. Fung

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January 1, 2010

Semi-automated protein binding methodology using equilibrium dialysis and a novel mixed-matrix cassette approach

Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549

Emile G. Plise; Daniel Tran; Laurent Salphati

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January 1, 2010

Factors affecting the viscosity in high concentration solutions of different monoclonal antibodies

Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549

Sandeep Yadav; Steven J. Shire; Devendra S. Kalonia

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January 1, 2010

Standardizing rodent trimming and embedding guidelines for histology: Improving efficiency in the laboratory

Journal of Histotechnology, ISSN: 01478885

Monika Larson; Taylor; Marjie Van Hoy

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January 1, 2010

Surface expression of precursor N-cadherin promotes tumor cell invasion

Neoplasia (United States), ISSN: 14765586 15228002

Deborah Maret; Eugenia Gruzglin; Mohamad Seyed Sadr; Vincent Siu; Shan; Alexander W. Koch; Nabil G. Seidah; Rolando F. del Maestro; David R. Colman

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January 1, 2010

Molecular mechanisms of regulatory T cell development and suppressive function

Progress in Molecular Biology and Translational Science, ISSN: 18771173

Kim

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January 1, 2010

Cell biology redux.

Molecular Biology of the Cell, ISSN: 19394586

Ira Mellman

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January 1, 2010

Molecular biomarker analyses using circulating tumor cells

PLoS ONE, ISSN: 19326203

Elizabeth A. Punnoose; Siminder Atwal; Jill M. Spoerke; Heidi Savage; Ajay Pandita; Ru-Fang Yeh; Andrea Pirzkall; Bernard M. Fine; Lukas Amler; Daniel S. Chen; Lackner

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January 1, 2010

Questions about coverage accompany new fully implantable hearing system

Managed Care, ISSN: 10623388

Thomas Morrow

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January 1, 2010

On the possibility of self-induction of drug protein binding

Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549

Leonid M. Berezhkovskiy

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January 1, 2010

Randomized, double-masked, sham-controlled trial of ranibizumab for neovascular age-related macular degeneration: PIER study year 2

American Journal of Ophthalmology, ISSN: 00029394

Prema Abraham; Huibin Yue; Laura J. Wilson

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January 1, 2010

Structure of the Complex between HER2 and an Antibody Paratope Formed by Side Chains from Tryptophan and Serine

Journal of Molecular Biology, ISSN: 00222836

Robert D. Fisher; Ultsch; Andreas Lingel; Gabriele Schaefer; Lily Shao; Sara Birtalan; Sachdev S. Sidhu; Eigenbrot

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January 1, 2010

Effect of temperature, pH, dissolved oxygen, and hydrolysate on the formation of triple light chain antibodies in cell culture.

Biotechnology Progress, ISSN: 15206033

Natalia Gomez; Jun Ouyang; Mary D. H. Nguyen; Abigail R Vinson; Andy Lin; Inn H. Yuk

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January 1, 2010

Monoclonal antibody purification using cationic polyelectrolytes: an alternative to column chromatography.

Biotechnology Progress, ISSN: 15206033

Thanmaya Peram; Paul McDonald; Jayme N. Carter-Franklin; Fahrner

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January 1, 2010

Treatment outcomes by tumor histology in eastern cooperative group study E4599 of bevacizumab with paclitaxel/carboplatin for advanced non-small cell lung cancer

Journal of Thoracic Oncology, ISSN: 15561380 15560864

Alan Sandler; Jing Yi; Suzanne Dahlberg; Margaret M. Kolb; Lisa I. Wang; Julie Hambleton; Joan H. Schiller; David H. Johnson

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January 1, 2010

Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency

Nature Genetics, ISSN: 15461718 10614036

Ricardo C. Ferreira; Qiang Pan-Hammarström; Robert R. Graham; Vesela Gateva; Gumersindo Fontán; Annette T. Lee; Ward Ortmann; Elena Urcelay; Miguel Fernández-Arquero; Concepción Núñez; Gudmundur Jorgensen; Björn R. Ludviksson; Sinikka Koskinen; Katri Haimila; Hilary F. Clark; Lars Klareskog; Peter K. Gregersen; Timothy W. Behrens; Lennart Hammarström

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January 1, 2010

Anti-CD22-MCC-DM1: An antibody-drug conjugate with a stable linker for the treatment of non-Hodgkin's lymphoma

Leukemia, ISSN: 14765551 08876924

Andrew G. Polson; Marna Williams; Gray; Reina N. Fuji; Kirsten Achilles Poon; Jacqueline McBride; Helga Raab; Thomas Januario; MaryAnn Go; Jeffrey Lau; Shang-Fan Yu; Du; Franklin Fuh; Christine Tan; Yan Wu; Wei-Ching Liang; Saileta Prabhu; Jean-Philippe Stephan; Hongo; Randall Dere; Rong Deng; Cullen; Ruth De Tute; Bennett; Andy Rawstron; Andrew S. Jack; Allen Ebens

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January 1, 2010

Characterization of a nutrient feed precipitate from an E. coli fermentation process.

Biotechnology Progress, ISSN: 15206033

Lauren Speciner; Erin Mallon; Susan Leung; Mike Laird; Osigwe Esue

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January 1, 2010

RTM3, which controls long-distance movement of potyviruses, is a member of a new plant gene family encoding a meprin and TRAF homology domain-containing protein

Plant Physiology, ISSN: 15322548 00320889

Patrick Cosson; Luc Sofer; Quang Hien Le; Valérie Léger; Valérie Schurdi-Levraud; Steven A. Whitham; Miki L. Yamamoto; Suresh Gopalan; Olivier le Gall; Thierry Candresse; James C. Carrington; Frédéric Revers

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January 1, 2010

Noncompartmental kinetic analysis of DCE-MRI data from malignant tumors: Application to glioblastoma treated with bevacizumab

Magnetic Resonance in Medicine, ISSN: 15222594 07403194

Ruediger E. Port; Lisa J. Bernstein; Daniel P. Barboriak; Lu Xu; Timothy P.L. Roberts; Nicholas Van Bruggen

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January 1, 2010

Vascular endothelial growth factor and age-related macular degeneration: From basic science to therapy

Nature Medicine, ISSN: 1546170X 10788956

Napoleone Ferrara

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January 1, 2010

Molecular dynamics simulations of hydrotropic solubilization and self-aggregation of nicotinamide

Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549

Yong Cui; Chenyue Xing; Yingqing Ran

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January 1, 2010

The chemical toolbox for monitoring protein fatty acylation and prenylation

Nature Chemical Biology, ISSN: 15524469 15524450

Rami N. Hannoush; Jinglucy Sun

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January 1, 2010

O-fucose modulates notch-controlled blood lineage commitment

American Journal of Pathology, ISSN: 15252191 00029440

Quanjian Yan; David Yao; Lebing L. Wei; Yuanshuai Huang; Jay Myers; Lihua Zhang; Wei Xin; Jeongsup Shim; Yunfang Man; Bronislawa Petryniak; Stanton Gerson; John Lowe; Lan Zhou

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January 1, 2010

Incidence of New Choroidal Neovascularization in Fellow Eyes of Patients Treated in the MARINA and ANCHOR Trials

American Journal of Ophthalmology, ISSN: 00029394

Irene Barbazetto; Namrata Saroj; Howard Shapiro; Pamela Wong; Allen C. Ho; K. Bailey Freund

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January 1, 2010

Ranibizumab for Macular Edema following Central Retinal Vein Occlusion. Six-Month Primary End Point Results of a Phase III Study

Ophthalmology, ISSN: 01616420

David M. Brown; Peter A. Campochiaro; Rishi Singh; Zhengrong Li; Sarah Gray; Namrata Saroj; Amy Chen Rundle; Roman G. Rubio; Wendy Yee Murahashi

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January 1, 2010

Early menstrual characteristics associated with subsequent diagnosis of endometriosis

American Journal of Obstetrics and Gynecology, ISSN: 00029378

Susan A. Treloar; Tanya A. Bell; Christina M. Nagle; David M. Purdie; Adèle C. Green

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January 1, 2010

Ranibizumab for Macular Edema following Branch Retinal Vein Occlusion. Six-Month Primary End Point Results of a Phase III Study

Ophthalmology, ISSN: 01616420

Peter A. Campochiaro; Jeffrey S. Heier; Leonard Feiner; Sarah Gray; Namrata Saroj; Amy Chen Rundle; Wendy Yee Murahashi; Roman G. Rubio

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