Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 9001 - 9050 OF 15217 RESULTS

Oncogenic activating mutations are associated with local copy gain
Molecular Cancer Research, ISSN: 15417786
Barmak Modrek; Lin Ge; Ajay Pandita; Eva Lin; Sankar Mohan; Peng Yue; Steve Guerrero; William M. Lin; Thinh Q. Pham; Zora Modrusan; Somasekar Seshagiri; Howard M. Stern; Waring; Levi A. Garraway; John Chant; David Stokoe; Guy Cavet
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A phase IB trial of intravenous INO-1001 plus oral temozolomide in subjects with unresectable stage-III or IV melanoma
Cancer Investigation, ISSN: 07357907 15324192
Agop Y. Bedikian; Nicholas E. Papadopoulos; Kevin B. Kim; Wen-Jen Hwu; Jade Homsi; Michelle R. Glass; Suzanne Cain; Patrick J. Rudewicz; Laurent Vernillet; Patrick Hwu
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European population substructure is associated with mucocutaneous manifestations and autoantibody production in systemic lupus erythematosus
Arthritis and Rheumatism, ISSN: 00043591 15290131
Sharon A. Chung; Tian; Kimberly E. Taylor; Annette T. Lee; Ward Ortmann; Geoffrey Hom; Robert R. Graham; Joanne Nititham; Jennifer A. Kelly; Jean Morrisey; Hui Wu; Hong Yin; Marta E. Alarcón-Riquelme; Betty P. Tsao; John B. Harley; Patrick M. Gaffney; Kathy L. Moser; Manzi; Michelle Petri; Peter K. Gregersen; Carl D. Langefeld; Timothy W. Behrens; Michael F. Seldin; Lindsey A. Criswell
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Subcellular compartmentalization of FADD as a new level of regulation in death receptor signaling
FEBS Journal, ISSN: 1742464X 17424658
Niko Föger; Silvia Bulfone-Paus; Andrew A. Chan; Kyeong-Hee Lee
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Paracrine hedgehog signaling in cancer
Cancer Research, ISSN: 00085472 15387445
Jan-Willem Theunissen; Frederic J. De Sauvage
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Churg-Strauss syndrome in patients treated with omalizumab
Chest, ISSN: 19313543 00123692
Michael E. Wechsler; Dennis A. Wong; Mary K. Miller; Lisa Lawrence-Miyasaki
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Antibody binding to a tethered vesicle assembly using QCM-D
Analytical Chemistry, ISSN: 00032700
Ankit Patel; Kay K. Kanazawa; Curtis W. Frank
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Health benefit costs and absenteeism due to insomnia from the employer's perspective: A retrospective, case-control, database study
Journal of Clinical Psychiatry, ISSN: 01606689
Nathan L. Kleinman; Richard A. Brook; Justin Doan; Arthur K. Melkonian; Robert W. Baran
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Molecular predictors of response to a humanized anti-insulin-like growth factor-I receptor monoclonal antibody in breast and colorectal cancer
Molecular Cancer Therapeutics, ISSN: 15357163
Jiping Zha; Carol O'Brien; Heidi Savage; Huw; Fiona Zhong; Berry; Gail L. Phillips; Luis; Guy Cavet; Xiaolan Hu; Lukas Amler; Lackner
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Prostate-specific Klf6 inactivation impairs anterior prostate branching morphogenesis through increased activation of the Shh pathway
Journal of Biological Chemistry, ISSN: 00219258 1083351X
Ching Ching Leow; Bu-Er Wang; Ross; Sara M. Chan; Jiping Zha; Richard A. D. Carano; Gretchen D. Frantz; Michael M. Shen; Frederic J. De Sauvage; Gao
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Comparative assessment of substrates and activity based probes as tools for non-invasive optical imaging of cysteine protease activity
PLoS ONE, ISSN: 19326203
Galia Blum; Robby M. Weimer; Laura E. Edgington; Walter Adams; Matthew Bogyo
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Phosphorylation of a borealin dimerization domain is required for proper chromosome segregation
Biochemistry, ISSN: 00062960
Eric Bourhis; Andreas Lingel; Qui Phung; Wayne J. Fairbrother; Andrea G Cochran
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Development of a microarray platform for FFPET profiling: Application to the classification of human tumors
Journal of Translational Medicine, ISSN: 14795876
Sven Duenwald; Mingjie Zhou; Yanqun Wang; Serguei Lejnine; Amit Kulkarni; Jaime Graves; Ryan Smith; John C. Castle; George Tokiwa; Bernard M. Fine; Hongyue Dai; Thomas Fare; Matthew Marton
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Membrane proteins follow multiple pathways to the basolateral cell surface in polarized epithelial cells
Journal of Cell Biology, ISSN: 00219525 00219525
Glen A. Farr; Mike Hull; Ira Mellman; Michael J. Caplan
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Two-dimensional liquid chromatographic methods to examine phenylboronate interactions with recombinant antibodies
Journal of Chromatography A, ISSN: 00219673
Boyan Zhang; Sean Mathewson; Huifen Chen
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Navigating the Deubiquitinating Proteome with a CompPASS
Cell, ISSN: 00928674
Peter K Jackson
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Type I interferon receptor controls B-cell expression of nucleic acid-sensing Toll-like receptors and autoantibody production in a murine model of lupus
Arthritis Research and Therapy, ISSN: 14786354 14786362
Donna L. Thibault; Kareem L. Graham; Lowen Y. Lee; Imelda Balboni; Paul J. Hertzog; Paul J. Utz
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Assigning large proteins in the solid state: A MAS NMR resonance assignment strategy using selectively and extensively 13C-labelled proteins
Journal of Biomolecular NMR, ISSN: 09252738 15735001
Victoria A. Higman; Jeremy Flinders; Matthias Hiller; Stefan Jehle; Stefan Markovic; Sebastian Fiedler; Barth-Jan van Rossum; Hartmut Oschkinat
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Antagonism of c-IAP and XIAP proteins is required for efficient induction of cell death by small-molecule IAP antagonists
ACS Chemical Biology, ISSN: 15548929
Chudi O. Ndubaku; Eugene Varfolomeev; Lan Wang; Zobel; Kevin Lau; Linda O. Elliott; Brigitte Maurer; Anna V. Fedorova; Jasmin N. Dynek; Michael F. T. Koehler; Sarah G. Hymowitz; Vickie Tsui; Deshayes; Wayne J. Fairbrother; Flygare; Domagoj Vucic
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Imaging the lipidome: ω-alkynyl fatty acids for detection and cellular visualization of lipid-modified proteins
ACS Chemical Biology, ISSN: 15548929
Rami N. Hannoush; Natalia Arenas-Ramirez
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IL-33 Raises Alarm
Immunity, ISSN: 10747613
Lamkanfi; Vishva M. Dixit
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Fear of commitment: Hes1 protects quiescent fibroblasts from irreversible cellular fates
Cell Cycle, ISSN: 15514005 15384101
Liyun Sang; Hilary A. Coller
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Clinical and immunogenetic prognostic factors for radiographic severity in ankylosing spondylitis
Arthritis Care and Research, ISSN: 21514658
Michael M. Ward; Matthew R. Hendrey; James D. Malley; Thomas J. Learch; John C. Davis; John D. Reveille; Michael Weisman
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CAPS activity in priming vesicle exocytosis requires CK2 phosphorylation
Journal of Biological Chemistry, ISSN: 00219258 1083351X
Mari Nojiri; Kelly M. Loyet; Vadim A. Klenchin; Gregory Kabachinski; Thomas F.J. Martin; Thomas F.J. Martin
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Wnt signaling is regulated by endoplasmic reticulum retention
PLoS ONE, ISSN: 19326203
J. Susie Zoltewicz; Amir M. Ashique; Youngshik Choe; Gena Lee; Stacy Taylor; Khanhky Phamluong; Mark J. Solloway; Andrew S. Peterson
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CAPS activity in priming vesicle exocytosis requires CK2 phosphorylation
Journal of Biological Chemistry, ISSN: 00219258 1083351X
Mari Nojiri; Kelly M. Loyet; Vadim A. Klenchin; Gregory Kabachinski; Thomas F.J. Martin
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Reassessment of corticospinal tract regeneration in Nogo-deficient mice
Journal of Neuroscience, ISSN: 02706474 15292401
Jae K. Lee; Andrea F. Chan; Sen M. Luu; Yuhong Zhu; Carole Ho; Marc Tessier-Lavigne; Binhai Zheng
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Scalable total synthesis and biological evaluation of haouamine A and its atropisomer
Journal of the American Chemical Society, ISSN: 00027863
Noah Z. Burns; Irina N. Krylova; Rami N. Hannoush; Phil S. Baran
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Levels of microparticle tissue factor activity correlate with coagulation activation in endotoxemic mice
Journal of Thrombosis and Haemostasis, ISSN: 15387933 15387836
Jian-Guo Wang; Manly; Daniel Kirchhofer; Rafal Pawlinski; Nigel Mackman
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Regulation of TLR7/9 responses in plasmacytoid dendritic cells by BST2 and ILT7 receptor interaction
Journal of Experimental Medicine, ISSN: 00221007 15409538
Wei Cao; Laura Bover; Minkwon Cho; Xiaoxia Wen; Shino Hanabuchi; Musheng Bao; David B. Rosen; Yi-Hong Wang; Joanne L. Shaw; Qiumei Du; Chun Li; Naoko Arai; Zhengbin Yao; Lewis L. Lanier; Yong-Jun Liu
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Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from TH-17, TH1 and TH2 cells
Nature Immunology, ISSN: 15292908 15292916
Sara Trifari; Charles D. Kaplan; Elise H. Tran; Natasha K Crellin; Hergen Spits
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STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing
Journal of Experimental Medicine, ISSN: 00221007 15409538
Geethanjali Pickert; Clemens Neufert; Moritz Leppkes; Yan Zheng; Nadine Wittkopf; Moritz Warntjen; Hans-Anton Lehr; Sebastian Hirth; Benno Weigmann; Stefan Wirtz; Wenjun Ouyang; Markus F. Neurath; Christoph Becker
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Unbound brain concentration determines receptor occupancy: A correlation of drug concentration and brain serotonin and dopamine reuptake transporter occupancy for eighteen compounds in rats
Drug Metabolism and Disposition, ISSN: 00909556 1521009X
Xingrong Liu; Olga Vilenski; Joyce Kwan; Subbu Apparsundaram; Robert Weikert
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Targeted depletion of lymphotoxin-α-expressing T H 1 and T H 17 cells inhibits autoimmune disease
Nature Medicine, ISSN: 10788956 1546170X
Eugene Y. Chiang; Ganesh Kolumam; Xin Yu; Michelle Francesco; Ivelja; Ivan Peng; Gribling; Jean Shu; Wyne P. Lee; Refino; Mercedesz Balazs; Andres Paler Martinez; Allen Nguyen; Judy Young; Kai H. Barck; Richard A. D. Carano; Ron Ferrando; Laurie Diehl; Devavani Chatterjea; Jane L. Grogan
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Measurements of birth defect prevalence: Which is most useful as a comparator group for pharmaceutical pregnancy registries?
Birth Defects Research Part A - Clinical and Molecular Teratology, ISSN: 15420752 15420760
Angela E. Scheuerle; Vani X. Vannappagari; Mary K. Miller
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Player RanKings: Using coefficient of variation to measure MLB players' worth
Quality Progress, ISSN: 0033524X
Julia E. Seaman; Elaine Allen
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Preclinical evaluation of carcinoembryonic cell adhesion molecule (CEACAM) 6 as potential therapy target for pancreatic adenocarcinoma
Journal of Pathology, ISSN: 00223417 10969896
Laura A. Strickland; Ross; Simon P. Williams; Ross; Maria Romero; Spencer; Erickson; Julie Sutcliffe; Caroline Verbeke; Paul G. Polakis; Nicholas Van Bruggen; Koeppen
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Dlx1&2 and Mash1 transcription factors control MGE and CGE patterning and differentiation through parallel and overlapping pathways
Cerebral Cortex, ISSN: 10473211 14602199
Jason E. Long; Inma Cobos; Gregory B. Potter; John L. R. Rubenstein
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Differential roles of Netrin-1 and its receptor DCC in inferior olivary neuron migration
Molecular and Cellular Neuroscience, ISSN: 10447431
Séverine Marcos; Stéphanie Backer; Frédéric Causeret; Marc Tessier-Lavigne; Evelyne Bloch-Gallego
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Deconvolution of blood microarray data identifies cellular activation patterns in systemic lupus erythematosus
PLoS ONE, ISSN: 19326203
Abbas Alexander; Kristen Wolslegel; Dhaya Seshasayee; Zora Modrusan; Hilary F. Clark
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Second International Conference on Accelerating Biopharmaceutical Development March 9-12, 2009, Coronado, CA, USA
Biotechnology Progress, ISSN: 87567938
Janice M. Reichert; Nitya M. Jacob; Ashraf Amanullah
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MBX-102/JNJ39659100, a novel peroxisome proliferator-activated receptor-ligand with weak transactivation activity retains antidiabetic properties in the absence of weight gain and edema
Molecular Endocrinology, ISSN: 08888809
Francine M. Gregoire; Fang Zhang; Holly J. Clarke; Thomas A. Gustafson; Dorothy D. Sears; Svetlana Favelyukis; James Lenhard; Dennis Rentzeperis; L. Edward Clemens; Yi Mu; Brian E. Lavan
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Development of prophylactic and therapeutic vaccines using the ISCOMATRIX adjuvant
Immunology and Cell Biology, ISSN: 08189641 14401711
Eugene Maraskovsky; Max Schnurr; Nicholas S. Wilson; Neil C Robson; Jeff Boyle; Debbie Drane
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Removal of endogenous retrovirus-like particles from CHO-cell derived products using Q sepharose fast flow chromatography
Biotechnology Progress, ISSN: 87567938
Daniel M. Strauss; Scott Lute; Kurt Brorson; Gregory S. Blank; Qi Chen; Bin Yang
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The structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signaling
Nature Structural and Molecular Biology, ISSN: 15459993 15459985
Ivan Bosanac; Henry R. Maun; Suzie J. Scales; Xiaohui Wen; Andreas Lingel; J.Fernando Bazan; Frederic J. De Sauvage; Sarah G. Hymowitz; Lazarus
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Homeless women's personal networks: Implications for understanding risk behavior
Human Organization, ISSN: 00187259
Joan Tucker; David Kennedy; Gery Ryan; Suzanne Wenzel; Daniela Golinelli; James L. Zazzali
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In vivo antitumor activity of MEK and phosphatidylinositol 3-kinase inhibitors in basal-like breast cancer models
Clinical Cancer Research, ISSN: 10780432
Klaus P. Hoeflich; Carol O'Brien; Zachary Boyd; Guy Cavet; Steve Guerrero; Kenneth Jung; Thomas Januario; Heidi Savage; Elizabeth A. Punnoose; Tom Truong; Wei Zhou; Berry; Lesley J. Murray; Lukas Amler; Marcia Belvin; Lori S. Friedman; Lackner
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Differential role of the Ca2+ sensor synaptotagmin VII in macrophages and dendritic cells
Immunobiology, ISSN: 01712985
Steven M. Becker; Lélia Delamarre; Ira Mellman; Norma W. Andrews
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Immunogenicity of biologically-derived therapeutics: Assessment and interpretation of nonclinical safety studies
Regulatory Toxicology and Pharmacology, ISSN: 02732300 10960295
Rafael Ponce; Leslie Abad; Lakshmi Amaravadi; Thomas R. Gelzleichter; Elizabeth Gore; Green; Shalini Gupta; Danuta Herzyk; Christopher Hurst; Inge A. Ivens; Thomas Kawabata; Curtis Maier; Barbara Mounho; Bonita Rup; Gopi Shankar; Holly W. Smith; Peter Thomas; Daniel Wierda
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Technology comparisons for anti-therapeutic antibody and neutralizing antibody assays in the context of an anti-TNF pharmacokinetic study
Journal of Immunological Methods, ISSN: 00221759
Kelly M. Loyet; Rong Deng; Wei-Ching Liang; Yan Wu; Henry B. Lowman; Laura DeForge
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