Scientists / Publications

Publications

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DISPLAYING 9051 - 9100 OF 15217 RESULTS

Expression and activity of the efflux transporters ABCB1, ABCC2 and ABCG2 in the human colorectal carcinoma cell line LS513
European Journal of Pharmaceutical Sciences, ISSN: 09280987
Laurent Salphati; Emile G. Plise; Guangmin Li
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Novel therapeutic targets along the Th17 pathway
European Journal of Immunology, ISSN: 00142980 15214141
Wenjun Ouyang; Ellen H. Filvaroff; Yan Hu; Jane L. Grogan
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Development of novel drugs targeting inhibitors of apoptosis
Future Oncology, ISSN: 14796694 17448301
Flygare; Domagoj Vucic
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Finding and achieving value in cancer care
JNCCN Journal of the National Comprehensive Cancer Network, ISSN: 15401405 15401413
Clifford Goodman; Joseph S. Bailes; Stephen B. Edge; A. Mark Fendrick; Scott Gottlieb; Robert Mass; Lee N. Newcomer; Lynn Zonakis
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Toward an effective targeted chemotherapy for multiple myeloma
Clinical Cancer Research, ISSN: 10780432
Andrew G. Polson; Mark X. Sliwkowski
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Multi-round virus filter integrity test sensitivity
Biotechnology and Bioengineering, ISSN: 00063592 10970290
Chris Dowd
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Suppression of HER2/HER3-mediated growth of breast cancer cells with combinations of GDC-0941 PI3K inhibitor, trastuzumab, and pertuzumab
Clinical Cancer Research, ISSN: 10780432
Evelyn Yao; Wei Zhou; Si Tuen Lee-Hoeflich; Tom Truong; Matthias Peter; Jeffrey Eastham-Anderson; Nicholas Lewin-Koh; Bert Gunter; Marcia Belvin; Lesley J. Murray; Lori S. Friedman; Mark X. Sliwkowski; Klaus P. Hoeflich
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Engineering human IgG1 affinity to human neonatal Fc receptor: Impact of affinity improvement on pharmacokinetics in primates
Journal of Immunology, ISSN: 00221767 15506606
Yik Andy Yeung; Maya Leabman; Jonathan S. Marvin; Julia Qiu; Adams; Samantha Lien; Melissa A. Starovasnik; Henry B. Lowman
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Interaction of IF2 with the ribosomal GTPase-associated center during 70S initiation complex formation
Biochemistry, ISSN: 00062960
Haiou Qin; Christina Grigoriadou; Barry S. Cooperman
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Targeting interferon alpha subtypes in serum: A comparison of analytical approaches to the detection and quantitation of proteins in complex biological matrices
Journal of Proteome Research, ISSN: 15353893
Anita Izrael-Tomasevic; Lilian Phu; Qui Phung; Jennie R. Lill; David Arnott
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Slow binding inhibition and mechanism of resistance of non-nucleoside polymerase inhibitors of Hepatitis C virus
Journal of Biological Chemistry, ISSN: 00219258 1083351X
Julie Qi Hang; Yanli Yang; Seth F. Harris; Vincent J.P. Leveque; Hannah J. Whittington; Sonal Rajyaguru; Gloria Ao-Leong; Matthew F. McCown; April Wong; Anthony M. Giannetti; Sophie Le Pogam; Francisco Talamás; Nick Cammack; Nájera; Klumpp
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Hedgehog Signaling Is Dispensable for Adult Murine Hematopoietic Stem Cell Function and Hematopoiesis
Cell Stem Cell, ISSN: 19345909
Inga Hofmann; Elizabeth H. Stover; Dana E. Cullen; Junhao Mao; Kelly J. Morgan; Benjamin H. Lee; Michael G. Kharas; Peter G. Miller; Melanie G. Cornejo; Rachel Okabe; Scott A. Armstrong; Nico Ghilardi; Stephen Gould; Frederic J. De Sauvage; Andrew P. McMahon; D. Gary Gilliland
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Axotomy-induced smad1 activation promotes axonal growth in adult sensory neurons
Journal of Neuroscience, ISSN: 02706474 15292401
Hongyan Zou; Carole Ho; Karen G. Wong; Marc Tessier-Lavigne
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Characterization of multiple stable conformers of the EC5 domain of E-cadherin and the interaction of EC5 with E-cadherin peptides
Chemical Biology and Drug Design, ISSN: 17470277
Kai Zheng; Jennifer S. Laurence; Krzysztof Kuczera; Gennady Verkhivker; C. Russell Middaugh; Teruna J. Siahaan
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Non-invasive monitoring provides fast payback
Chemical Processing, ISSN: 00092630
Chris Stubbs
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PET of glial metabolism using 2-18F-fluoroacetate
Journal of Nuclear Medicine, ISSN: 01615505
Jan Marik; Annie Ogasawara; Baby Martin-McNulty; Ross; Judith E. Flores; Herman S. Gill; Jeff N. Tinianow; Alexander N. Vanderbilt; Merry C. Nishimura; Franklin V. Peale Jr.; Cinthia V Pastuskovas; Joan M. Greve; Nicholas Van Bruggen; Simon P. Williams
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Phase I study of the effect of gastric acid pH modulators on the bioavailability of oral dasatinib in healthy subjects
Journal of Clinical Pharmacology, ISSN: 00912700 15524604
Timothy Eley; Feng R. Luo; Shruti Agrawal; Ashish Sanil; James Manning; Tong Li; Anne Blackwood-Chirchir; Richard Bertz
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Assessment of a sixteen-week training program on strength, pain, and function in rheumatoid arthritis patients
Journal of Clinical Rheumatology, ISSN: 10761608
Hilary G. Flint-Wagner; Jeffrey Lisse; Timothy G. Lohman; Scott B. Going; Terri Guido; Ellen Cussler; Donald Gates; David E. Yocum
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Review of recent genome-wide association scans in lupus
Journal of Internal Medicine, ISSN: 09546820 13652796
Robert R. Graham; Geoffrey Hom; Ward Ortmann; Timothy W. Behrens
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Analysis of charge heterogeneities in mAbs using imaged CE
Electrophoresis, ISSN: 01730835 15222683
Xiaoping Z. He; Amy H. Que; Jim J. Mo
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Evaluation of multiple in vitro systems for assessment of CYP3A4 induction in drug discovery: Human hepatocytes, pregnane X receptor reporter gene, and Fa2N-4 and HepaRG Cells
Drug Metabolism and Disposition, ISSN: 00909556 1521009X
Dermot F. McGinnity; George Zhang; Jane R. Kenny; Geraldine A. Hamilton; Sara Otmani; Karen R. Stams; Suzzette Haney; Patrick Brassil; David M Stresser; Robert J. Riley
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Mechanisms of Hedgehog pathway activation in cancer and implications for therapy
Trends in Pharmacological Sciences, ISSN: 01656147
Suzie J. Scales; Frederic J. De Sauvage
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An analytical system for the characterization of highly heterogeneous mixtures of N-linked oligosaccharides
Analytical Biochemistry, ISSN: 10960309 00032697
Briggs; Rodney Keck; Stacey Ma; Wendy Lau; Andrew J.S. Jones
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A class of 2,4-bisanilinopyrimidine Aurora A inhibitors with unusually high selectivity against Aurora B
Journal of Medicinal Chemistry, ISSN: 00222623
Ignacio Aliagas; Burdick; Laura B. Corson; Jennafer Dotson; Jason H. Drummond; Carter Fields; Oscar W Huang; Thomas Hunsaker; Tracy L. Kleinheinz; Elaine B. Krueger; Jun Liang; John Moffat; Gail L. Phillips; Rebecca Pulk; Thomas E. Rawson; Ultsch; Leslie Walker; Wiesmann; Birong Zhang; Bing-Yan Zhu; Andrea G Cochran
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Combined targeting of BRAF and CRAF or BRAF and PI3K effector pathways is required for efficacy in NRAS mutant tumors
PLoS ONE, ISSN: 19326203
Bijay S. Jaiswal; Vasantharajan Janakiraman; Noelyn Kljavin; Jeffrey Eastham-Anderson; James Cupp; Yuxin Liang; David P. Davis; Klaus P. Hoeflich; Somasekar Seshagiri
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Primary Sjögren's Syndrome: Health experiences and predictors of health quality among patients in the United States
Health and Quality of Life Outcomes, ISSN: 14777525
Barbara Segal; Simon J. Bowman; Philip C. Fox; Frederick B. Vivino; Nandita Murukutla; Jeff Brodscholl; Sarika Ogale; Lachy McLean
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MBX-102/JNJ39659100, a novel non-TZD selective partial PPAR-γ agonist lowers triglyceride independently of PPAR-α activation
PPAR Research, ISSN: 16874757 16874765
Francine M. Gregoire; Apurva Chandalia; Holly J. Clarke; L. Edward Clemens; Bindu Pandey; Vic Vicena; Paul Lee; Brian E. Lavan
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ATP-citrate lyase links cellular metabolism to histone acetylation
Science, ISSN: 00368075 10959203
Kathryn E. Wellen; Georgia Hatzivassiliou; Uma M. Sachdeva; Thi V. Bui; Justin R. Cross; Craig B. Thompson
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Development of a rapid sanitization solution for silica-based protein A affinity adsorbents
Journal of Chromatography A, ISSN: 00219673
Marc Rogers; Hiraoka-Sutow; Polly Mak; Fred Mann; Lebreton
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Effect of EDTA and methionine on preventing loss of viscosity of cellulose-based topical gel
AAPS PharmSciTech, ISSN: 15309932
Junyan A. Ji; Erika Ingham; John Wang
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Ubiquilins accelerate autophagosome maturation and promote cell survival during nutrient starvation
Autophagy, ISSN: 15548635 15548627
Elsa N. N'Diaye; Jayanta Debnath; Eric J. Brown
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Ion exchange chromatography of monoclonal antibodies: Effect of resin ligand density on dynamic binding capacity
Journal of Chromatography A, ISSN: 00219673
Ann Marie Hardin; Chithkala Harinarayan; Gunnar Malmquist; Andreas Axén; Robert Van Reis
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Surface extenders and an optimal pore size promote high dynamic binding capacities of antibodies on cation exchange resins
Journal of Chromatography A, ISSN: 00219673
David S. Hart; Chithkala Harinarayan; Gunnar Malmquist; Andreas Axén; Mandakini Sharma; Robert Van Reis
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Cullin3-Based Polyubiquitination and p62-Dependent Aggregation of Caspase-8 Mediate Extrinsic Apoptosis Signaling
Cell, ISSN: 00928674
Zhaoyu Jin; Yun Li; Pitti; David Lawrence; Victoria Pham; Jennie R. Lill; Avi Ashkenazi
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Erratum: Erythropoietin dosing in children with chronic kidney disease: Based on body size or on hemoglobin deficit? (Pediatric Nephrology (2009) 10.1007/s00467-008-0955-2)
Pediatric Nephrology, ISSN: 0931041X
Ruediger E. Port; Otto Mehls
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Characterization of deamidated peptide variants by micro-preparative capillary electrophoresis and mass spectrometry
Journal of Chromatography A, ISSN: 00219673
Lynn Gennaro; Oscar Salas-Solano
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A therapeutic antibody and its antigen form different complexes in serum than in phosphate-buffered saline: A study by analytical ultracentrifugation
Analytical Biochemistry, ISSN: 10960309 00032697
Barthélemy Demeule; Steven J. Shire; Jun Liu
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A developmentally regulated Myb domain protein regulates expression of a subset of stage-specific genes in Entamoeba histolytica
Cellular Microbiology, ISSN: 14625814 14625822
Gretchen M. Ehrenkaufer; Jason A. Hackney; Upinder Singh
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A nanocube plasmonic sensor for molecular binding on membrane surfaces
Nano Letters, ISSN: 15306984
William J. Galush; Sarah A. Shelby; Martin J. Mulvihill; Andrea Tao; Peidong Yang; Jay T. Groves
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The effects of c-Abl mutation on developing B cell differentiation and survival
International Immunology, ISSN: 09538178 14602377
Hans D. Brightbill; Mark S. Schlissel
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Analytical methods for inferring functional effects of single base pair substitutions in human cancers
Human Genetics, ISSN: 03406717 14321203
William Lee; Peng Yue; Zemin Zhang
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Small-molecule inhibitors of store-operated calcium entry
ChemMedChem, ISSN: 18607179 18607187
Zachary K. Sweeney; Ana Minatti; Donald Button; Silvia Patrick
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Docking for fragment inhibitors of AmpC β-lactamase
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424 10916490
Denise G. Teotico; Kerim Babaoglu; Gabriel J. Rocklin; Rafaela S. Ferreira; Anthony M. Giannetti; Brian K. Shoichet
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Pharmacokinetic analysis of irinotecan plus bevacizumab in patients with advanced solid tumors
Cancer Chemotherapy and Pharmacology, ISSN: 03445704
Crystal S. Denlinger; Rebecca Blanchard; Lu Xu; Coen A. Bernaards; Samuel Litwin; Cynthia Spittle; Daniel J. Berg; Susan McLaughlin; Maryann Redlinger; Andrew Dorr; Julie Hambleton; Scott N. Holden; Anne Kearns; Sara Kenkare-Mitra; Bert L. Lum; Neal J. Meropol; Peter J. O'Dwyer
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Ligand-Independent HER2/HER3/PI3K Complex Is Disrupted by Trastuzumab and Is Effectively Inhibited by the PI3K Inhibitor GDC-0941
Cancer Cell, ISSN: 15356108
Teemu T. Junttila; Robert W. Akita; Kathryn Parsons; Carter Fields; Gail L. Phillips; Lori S. Friedman; Deepak Sampath; Mark X. Sliwkowski
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The PRL -1149 G/T polymorphism and rheumatoid arthritis susceptibility
Arthritis and Rheumatism, ISSN: 00043591 15290131
Yvonne C. Lee; Soumya Raychaudhuri; Jing Cui; Immaculata De Vivo; Bo Ding; Lars Alfredsson; Leonid Padyukov; Karen H. Costenbader; Mark Seielstad; Robert R. Graham; Lars Klareskog; Peter K. Gregersen; Robert M. Plenge; Elizabeth W. Karlson
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How can we improve the translational landscape for a faster cure of type 1 diabetes?
Journal of Clinical Investigation, ISSN: 00219738 15588238
Matthias von Herrath; Andrew A. Chan
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Variation in the upstream region of P-Selectin (SELP) is a risk factor for SLE
Genes and Immunity, ISSN: 14664879 14765470
David L. Morris; Robert R. Graham; Erwig; Patrick M. Gaffney; Kathy L. Moser; Timothy W. Behrens; Timothy J. Vyse; Deborah S. Cunninghame Graham
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Efficacy and safety of erlotinib in patients with locally advanced or metastatic breast cancer
Breast Cancer Research and Treatment, ISSN: 01676806 15737217
Maura N. Dickler; Melody A. Cobleigh; Kathy Miller; Pam Klein; Eric P. Winer
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Predictive biomarkers in the development of oncology drugs: A therapeutic industry perspective
Clinical Pharmacology and Therapeutics, ISSN: 00099236 15326535
Bernard M. Fine; Lukas Amler
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