Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 9301 - 9350 OF 15217 RESULTS

Monitoring and control of cell culture bioreactors using on-line scanning dielectric spectroscopy
AIChE Annual Meeting, Conference Proceedings,
Cary F. Opel; Ashraf Amanullah
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How Do You Classify Asthma by Severity?
Clinical Asthma,
James E. Fish
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Recombinant protein production in escherichia coli
AIChE Annual Meeting, Conference Proceedings,
Jane Gunson; Mike Laird
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Trends in presenting characteristics and hospital mortality among patients with ST elevation and non-ST elevation myocardial infarction in the National Registry of Myocardial Infarction from 1990 to 2006
American Heart Journal, ISSN: 00028703 10976744
William J. Rogers; Paul D. Frederick; Edna Stoehr; John G. Canto; Joseph P. Ornato; C.Michael Gibson; Charles V. Pollack Jr.; Joel M. Gore; Nisha C. Chandra; Eric D. Peterson; William J. French
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Some features of the kinetics and equilibrium of drug binding to plasma proteins
Expert Opinion on Drug Metabolism and Toxicology, ISSN: 17425255
Leonid M. Berezhkovskiy
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High throughput ADME screening: Practical considerations, impact on the portfolio and enabler of in silico ADME models
Current Drug Metabolism, ISSN: 13892002
Cornelis E. Hop; Mark J. Cole; Ralph E. Davidson; David B. Duignan; James Federico; John S. Janiszewski; Kelly Jenkins; Suzanne Krueger; Rebecca Lebowitz; Theodore E. Liston; Walter Mitchell; Mark Snyder; Stefan J. Steyn; John R. Soglia; Christine Taylor; Troutman; John Umland; Michael West; Kevin M. Whalen; Veronica Zelesky; Sabrina X. Zhao
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The p85α subunit of class IA phosphatidylinositol 3-kinase regulates the expression of multiple genes involved in osteoclast maturation and migration
Molecular and Cellular Biology, ISSN: 02707306
Veerendra Munugalavadla; Sasidhar Vemula; Emily Sims; Subha Krishnan; Shi Chen; Jincheng Yan; Huijie Li; Paul J. Niziolek; Clifford Takemoto; Alexander G. Robling; Feng-Chun Yang; Reuben Kapur
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Automated monitoring of mammalian cell cultures via an auto-sampler and an integrated multi-functional off-line analyzer
AIChE Annual Meeting, Conference Proceedings,
Gayle E. Derfus; Daniel Abramzon; Meg Tung; Robert Kiss; Ashraf Amanullah
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Are health-care relationships important for mammography adherence in Latinas?
Journal of General Internal Medicine, ISSN: 08848734 15251497
Vanessa B. Sheppard; Judy Wang; Bin Yi; Toni Michelle Harrison; Shibao Feng; Elmer E. Huerta; Jeanne S. Mandelblatt
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Cooperation of the agonistic DR5 antibody apomab with chemotherapy to inhibit orthotopic lung tumor growth and improve survival
Clinical Cancer Research, ISSN: 10780432
Hongkui Jin; Renhui Yang; Ross; Fong; Richard A. D. Carano; Klara Totpal; David Lawrence; Zhong Zheng; Koeppen; Howard M. Stern; Ralph H. Schwall; Avi Ashkenazi
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Startle reactivity in children at risk for migraine
Clinical Neurophysiology, ISSN: 13882457
Roman Duncko; Lihong Cui; Jeffrey Hille; Christian Grillon; Kathleen R. Merikangas
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Analysis of the nucleotide sequence of the guinea pig cytomegalovirus (GPCMV) genome
Virology Journal, ISSN: 1743422X
Mark R. Schleiss; Alistair McGregor; K Yeon Choi; Shailesh V. Date; Xiaohong Cui; Michael A. McVoy
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Effects of cell culture conditions on antibody N-glycosylation- What causes high mannose 5 glycoform
AIChE Annual Meeting, Conference Proceedings,
Efren Pacis; Feng Li; Darren Brown; Robert Bayer
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Erratum: PCSK9 function and physiology (Journal of Lipid Research)
Journal of Lipid Research, ISSN: 00222275 15397262
Andrew S. Peterson; Loren G. Fong; Stephen G. Young
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Chirality vs. HOMFLY and Kauffman polynomials
Journal of Knot Theory and its Ramifications, ISSN: 02182165
Sandy Ganzell; Amy V. Kapp
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Independent development of hydrolysate-containing and hydrolysate-free cho cell culture processes yields different optimal conditions
AIChE Annual Meeting, Conference Proceedings,
Diane M. Wuest; Polina Rapoport; Deborah E. Pascoe
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Erratum: FGF15 promotes neurnogenesis and opposes FGF8 function during neocortical development (Neural Development (2008) 3 (31))
Neural Development, ISSN: 17498104
Ugo Borello; Inma Cobos; Jason E. Long; John R. McWhirter; Cornelis Murre; John L. R. Rubenstein
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The semaphorin receptor PlexinA3 mediates neuronal apoptosis during dorsal root ganglia development
Journal of Neuroscience, ISSN: 02706474 02706474
Ayal Ben-Zvi; Osnat Manor; Melitta Schachner; Avraham Yaron; Marc Tessier-Lavigne; Oded Behar
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Chapter 6 Mouse Models to Investigate Anti-Cancer Effects of VEGF Inhibitors
Methods in Enzymology, ISSN: 00766879
Yongping Crawford; Napoleone Ferrara
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Targeting HER2-positive breast cancer with trastuzumab-DM1, an antibody-cytotoxic drug conjugate
Cancer Research, ISSN: 00085472 15387445
Gail L. Phillips; Guangmin Li; Dugger; Lisa Crocker; Kathryn Parsons; Elaine Mai; Walter A. Blättler; John M. Lambert; Ravi Chari; Robert J. Lutz; Wai Lee T. Wong; Fred Jacobson; Koeppen; Ralph H. Schwall; Sara Kenkare-Mitra; Spencer; Mark X. Sliwkowski
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Laminin-332 is a substrate for hepsin, a protease associated with prostate cancer progression
Journal of Biological Chemistry, ISSN: 00219258 1083351X
Manisha Tripathi; Srinivas Nandana; Hironobu Yamashita; Rajkumar Ganesan; Daniel Kirchhofer; Vito Quaranta
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Directing cancer cells to self-destruct with pro-apoptotic receptor agonists
Nature Reviews Drug Discovery, ISSN: 14741776 14741784
Avi Ashkenazi
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PirB is a functional receptor for myelin inhibitors of axonal regeneration
Science, ISSN: 00368075 10959203
Jasvinder K. Atwal; Julie Pinkston-Gosse; Josh Syken; Scott Stawicki; Yan Wu; Carla J. Shatz; Marc Tessier-Lavigne
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Reflections
Neuron, ISSN: 08966273
Richard H. Scheller; John R. Nambu
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Formation of the blood - Brain barrier: Wnt signaling seals the deal
Journal of Cell Biology, ISSN: 00219525 00219525
Paul G. Polakis
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Coordinated protein sorting, targeting and distribution in polarized cells
Nature Reviews Molecular Cell Biology, ISSN: 14710072 14710080
Ira Mellman; W. James Nelson
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Effect of therapeutic integrin (CD11a) blockade with efalizumab on immune responses to model antigens in humans: Results of a randomized, single blind study
Journal of Investigative Dermatology, ISSN: 0022202X 15231747
James G. Krueger; Hans D. Ochs; Piyush Patel; Ellen Gilkerson; Emma Guttman-Yassky; Wolfgang Dummer
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Increased plasma concentrations of cytoskeletal and Aa2+-binding proteins and their peptides in psoriasis patients
Clinical Chemistry, ISSN: 00099147
Tatiana Plavina; Marina Hincapie; Eric Wakshull; Subramanyam; William S. Hancock
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BMP/SMAD1 signaling sets a threshold for the left/right pathway in lateral plate mesoderm and limits availability of SMAD4
Genes and Development, ISSN: 08909369 15495477
Milena B. Furtado; Mark J. Solloway; Vanessa J. Jones; Mauro W. Costa; Christine Biben; Orit Wolstein; Jost I. Preis; Duncan B. Sparrow; Yumiko Saga; Sally Dunwoodie; Elizabeth J. Robertson; Patrick P. L. Tam; Richard P. Harvey
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Evidence for an asialoglycoprotein receptor on nonparenchymal cells for O-linked glycoproteins
Journal of Pharmacology and Experimental Therapeutics, ISSN: 00223565 15210103
Stefanich; Song Ren; Dimitry Danilenko; Lim; An Song; Suhasini Iyer; Fielder
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Pharmacokinetics, metabolism, and excretion of torcetrapib, a cholesteryl ester transfer protein inhibitor, in humans
Drug Metabolism and Disposition, ISSN: 00909556 1521009X
Deepak Dalvie; Weichao Chen; Chenghong Zhang; Alfin D. Vaz; Teresa Smolarek; Loretta M. Cox; Jian Lin; R. Scott Obach
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The environmental impact of disposable technologies
BioPharm International, ISSN: 1542166X
Andrew Sinclair; Lindsay Leveen; Miriam Monge; Janice Lim; Stacey Cox
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Metabolic engineering of the non-sporulating, non-solventogenic Clostridium acetobutylicum strain M5 to produce butanol without acetone demonstrate the robustness of the acid-formation pathways and the importance of the electron balance
Metabolic Engineering, ISSN: 10967176 10967184
Ryan Sillers; Alison Chow; Bryan Tracy; Eleftherios T. Papoutsakis
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The response to combination therapy treatment regimens in severe/difficult-to-treat asthma
European Respiratory Journal, ISSN: 09031936 13993003
Campbell; Larry Borish; Tmirah Haselkorn; Lawrence Rasouliyan; June H. Lee; Sally E. Wenzel; Sean D. Sullivan
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Small RNAs with 5′-polyphosphate termini associate with a piwi-related protein and regulate gene expression in the single-celled eukaryote Entamoeba histolytica
PLoS Pathogens, ISSN: 15537366 15537374
Hanbang Zhang; Gretchen M. Ehrenkaufer; Justine M. Pompey; Jason A. Hackney; Upinder Singh
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Increased inflammatory gene expression in ABC transporter-deficient macrophages: Free cholesterol accumulation, increased signaling via toll-like receptors, and neutrophil infiltration of atherosclerotic lesions
Circulation, ISSN: 00097322 15244539
Laurent Yvan-Charvet; Carrie Welch; Tamara A. Pagler; Mollie Ranalletta; Lamkanfi; Seongah Han; Minako Ishibashi; Rong Li; Nan Wang; Alan R. Tall
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Transport of LDL-derived cholesterol from the NPC1 compartment to the ER involves the trans-Golgi network and the SNARE protein complex
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 10916490 00278424
Yasuomi Urano; Hiroshi Watanabe; Stephanie R. Murphy; Yohei Shibuya; Yong Geng; Andrew A. Peden; Catherine C. Y. Chang; Ta Yuan Chang
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Antixenograft tumor activity of a humanized anti-insulin-like growth factor-I receptor monoclonal antibody is associated with decreased AKT activation and glucose uptake
Molecular Cancer Therapeutics, ISSN: 15357163
Yonglei Shang; Yifan Mao; Jennifer Batson; Suzie J. Scales; Gail L. Phillips; Lackner; Klara Totpal; Simon P. Williams; Yang; Zhijun Tang; Zora Modrusan; Christine Tan; Wei-Ching Liang; Ping Tsai Siao; Alexander N. Vanderbilt; Kenji Kozuka; Klaus P. Hoeflich; Janet Y. Tien; Ross; Congfen Li; Hoon Lee Sang; An Song; Yan Wu; Jean-Philippe Stephan; Avi Ashkenazi; Jiping Zha
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Kinetics of Wnt-driven β-catenin stabilization revealed by quantitative and temporal imaging
PLoS ONE, ISSN: 19326203
Rami N. Hannoush
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A PDZ-Binding motif controls basolateral targeting of syndecan-1 along the biosynthetic pathway in polarized epithelial cells
Traffic, ISSN: 13989219 16000854
Sandra Maday; Eric Anderson; Henry C. Chang; James Shorter; Ayano Satoh; Jeff Sfakianos; Heike Fölsch; James M. Anderson; Zenta Walther; Ira Mellman
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Balancing between antitumor efficacy and autoimmune pathology in T-cell-mediated targeting of carcinoembryonic antigen
Cancer Research, ISSN: 00085472
Rinke Bos; Suzanne Van Duikeren; Hans Morreau; Kees Franken; Ton N. M. Schumacher; John B. Haanen; Sjoerd H. van der Burg; Cornelis J. M. Melief; Rienk Offringa
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Cross-species differential plasma protein binding of MBX-102/JNJ39659100: A novel PPAR-γ agonist
PPAR Research, ISSN: 16874757 16874765
Holly J. Clarke; Francine M. Gregoire; Fang Ma; Robert Martin; Spring Zhao; Brian E. Lavan
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Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents
Journal of Cell Biology, ISSN: 00219525 00219525
Michael Degtyarev; Ann De Mazière; Christine Orr; Jie Lin; Brian Lee; Janet Y. Tien; Wei Wei Prior; Suzanne Van Dijk; Hong Wu; Daniel C. Gray; David P. Davis; Howard M. Stern; Lesley J. Murray; Klaus P. Hoeflich; Judith Klumperman; Lori S. Friedman; Kui Lin
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Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents
Journal of Cell Biology, ISSN: 00219525 00219525
Michael Degtyarev; Ann De Mazière; Christine Orr; Jie Lin; Brian B. Lee; Janet Y. Tien; Wei Wei Prior; Suzanne Van Dijk; Hong Wu; Daniel C. Gray; David P. Davis; Howard M. Stern; Lesley J. Murray; Klaus P. Hoeflich; Judith Klumperman; Lori S. Friedman; Kui Lin
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γ-Glutamyltranspeptidase-mediated degradation of diclofenac-s-acyl- glutathione in vitro and in vivo in rat
Chemical Research in Toxicology, ISSN: 0893228X
Mark P. Grillo; Fengmei Hua; Kristi L. March; Leslie Z. Benet; Charles G. Knutson; Joseph A. Ware
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In vitro allergen challenge of peripheral blood induces differential gene expression in mononuclear cells of asthmatic patients: Inhibition of cytosolic phospholipase A2α overcomes the asthma-associated response
Clinical and Experimental Allergy, ISSN: 09547894 13652222
Whalen; Legault; Hang; Hill; Kasaian; Donaldson; Bensch; Bensch; Baker; Reddy; Wood; Ramarao; Ellis; Csimma; McKee; Clark; Ryan; Dorner; O'Toole
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Clinical pharmacokinetics of bevacizumab in patients with solid tumors
Cancer Chemotherapy and Pharmacology, ISSN: 03445704
Jian-Feng Lu; Rene Bruno; Stephen M. Eppler; Novotny; Bert L. Lum; Jacques Gaudreault
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Magnetic resonance imaging and spectroscopy for monitoring liver steatosis
Journal of Magnetic Resonance Imaging, ISSN: 10531807 15222586
Gary J. Cowin; Julie R. Jonsson; Judith D. Bauer; Susan Ash; Azmat Ali; Emma J. Osland; David M. Purdie; Andrew D. Clouston; Elizabeth E. Powell; Graham J. Galloway
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From the authors
American Journal of Respiratory and Critical Care Medicine, ISSN: 15354970 1073449X
Derek C. Angus; Walter T. Linde-Zwirble; Amber E. Barnato; Sherri L. Alexander
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A chemical screen in diverse breast cancer cell lines reveals genetic enhancers and suppressors of sensitivity to PI3K isoform-selective inhibition
Biochemical Journal, ISSN: 02646021
Neil E. Torbett; Antonio Luna-Moran; Zachary A. Knight; Andrew Houk; Mark Moasser; William Weiss; Kevan Shokat; David Stokoe
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