Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 9551 - 9600 OF 15217 RESULTS

Allergen skin tests and free IgE levels during reduction and cessation of omalizumab therapy
Journal of Allergy and Clinical Immunology, ISSN: 00916749
Jonathan Corren; Gail Shapiro; Reimann; Yamo Deniz; Dennis A. Wong; Daniel C. Adelman; Alkis Togias
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Duration of chronic toxicity studies for biotechnology-derived pharmaceuticals: Is 6 months still appropriate?
Regulatory Toxicology and Pharmacology, ISSN: 02732300 10960295
Janet Clarke; Christopher Hurst; Pauline L. Martin; John Vahle; Rafael Ponce; Barbara Mounho; Shawn Heidel; Laura Andrews; Theresa Reynolds; Joy A. Cavagnaro
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Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci
Nature Genetics, ISSN: 10614036 15461718
John B. Harley; Marta E. Alarcón-Riquelme; Lindsey A. Criswell; Chaim O. Jacob; Robert P. Kimberly; Kathy L. Moser; Betty P. Tsao; Timothy J. Vyse; Carl D. Langefeld; Swapan K. Nath; Joel M. Guthridge; Beth L. Cobb; Daniel B. Mirel; Miranda C. Marion; Adrienne H. Williams; Jasmin Divers; Wei Wang; Summer G. Frank; Bahram Namjou; Stacey B. Gabriel; Annette T. Lee; Peter K. Gregersen; Timothy W. Behrens; Kimberly E. Taylor; Michelle M.A. Fernando; Raphael Zidovetzki; Patrick M. Gaffney; Jeffrey C. Edberg; John D. Rioux; Joshua O. Ojwang; Judith A. James; Merrill; Gary S. Gilkeson; Michael F. Seldin; Hong Yin; Emily C. Baechler; Quan-Zhen Li; Edward K. Wakeland; Gail R. Bruner; Kenneth M. Kaufman; Jennifer A. Kelly
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Racial variation in the incidence, care, and outcomes of severe sepsis: Analysis of population, patient, and hospital characteristics
American Journal of Respiratory and Critical Care Medicine, ISSN: 1073449X 15354970
Amber E. Barnato; Sherri L. Alexander; Walter T. Linde-Zwirble; Derek C. Angus
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Netrin-1 is a novel myelin-associated inhibitor to axon growth
Journal of Neuroscience, ISSN: 02706474 02706474
Karin Löw; Maya Culbertson; Frank Bradke; Marc Tessier-Lavigne; Mark H. Tuszynski
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SAGA-mediated H2B deubiquitination controls the development of neuronal connectivity in the Drosophila visual system
EMBO Journal, ISSN: 02614189 14602075
Vikki M. Weake; Kenneth K. Lee; Sebastián Guelman; Chia-Hui Lin; Christopher Seidel; Susan M. Abmayr; Jerry L. Workman
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Dual effects of Tween 80 on protein stability
International Journal of Pharmaceutics, ISSN: 03785173
Wei Wang; Y. John Wang; Wang
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Construction and preclinical characterization of Fc-mGITRL for the immunotherapy of cancer
Clinical Cancer Research, ISSN: 10780432
Peisheng Hu; Robyn S. Arias; Rebecca E. Sadun; Yu-Chih Nien; Nan Zhang; Helen Sabzevari; M. E. Christine Lutsiak; Leslie A. Khawli; Alan L. Epstein
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Role for lysosomal enzyme β-hexosaminidase in the control of mycobacteria infection
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424 10916490
Ingrid Chou Koo; Yamini M. Ohol; Ping Wu; J. Hiroshi Morisaki; Jeffery S. Cox; Eric J. Brown
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Laboratory evolution of Escherichia coli thioredoxin for enhanced catalysis of protein oxidation in the periplasm reveals a phylogenetically conserved substrate specificity determinant
Journal of Biological Chemistry, ISSN: 00219258 1083351X
Lluis Masip; Daniel Klein-Marcuschamer; Shu Quan; James C. A. Bardwell; George Georgiou
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Response-independent survival benefit in metastatic colorectal cancer: A comparative analysis of N9741 and AVF2107
Journal of Clinical Oncology, ISSN: 0732183X
Grothey; Eric Hedrick; Robert Mass; Somnath Sarkar; Sam Suzuki; Ramesh K. Ramanathan; Herbert Hurwitz; Richard M. Goldberg; Daniel J. Sargent
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Synthetic antibodies for specific recognition and crystallization of structured RNA
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424 10916490
Jing-Dong Ye; Valentina Tereshko; John K. Frederiksen; Akiko Koide; Frederic A. Fellouse; Sachdev S. Sidhu; Shohei Koide; Anthony A. Kossiakoff; Joseph A. Piccirilli
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Targeting FGF19 inhibits tumor growth in colon cancer xenograft and FGF19 transgenic hepatocellular carcinoma models
Oncogene, ISSN: 09509232 14765594
Luc Desnoyers; Rama Pai; Ron Ferrando; Kathy Hötzel; Tom Le; Ross; Richard A. D. Carano; Aloma L. D'Souza; Jing Qing; Iman Mohtashemi; Avi Ashkenazi; French
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Accounting for interim analyses in the assessment of program expected net present value
Drug Information Journal, ISSN: 00928615
Lee D. Kaiser; Jeffrey D. Helterbrand; Hal V. Barron
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Cytokine, chemokine, and co-stimulatory fusion proteins for the immunotherapy of solid tumors
Handbook of Experimental Pharmacology, ISSN: 18650325 01712004
Leslie A. Khawli; Peisheng Hu; Alan L. Epstein
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DNA microarray gene expression profile of marginal zone versus follicular B cells and idiotype positive marginal zone B cells before and after immunization with Streptococcus pneumoniae
Journal of Immunology, ISSN: 15506606 00221767
Nicholas W. Kin; Dianna Crawford; Jiabin Liu; Timothy W. Behrens; John F. Kearney
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Oral involvement in primary Sjögren syndrome
Journal of the American Dental Association, ISSN: 00028177
Philip C. Fox; Simon J. Bowman; Barbara Segal; Frederick B. Vivino; Murukutla; Karen Choueiri; Sarika Ogale; Lachy McLean
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Therapeutic anti-VEGF antibodies
Handbook of Experimental Pharmacology, ISSN: 18650325 01712004
Samantha Lien; Henry B. Lowman
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Systematic comparison of gene expression between murine memory and naive B cells demonstrates that memory B cells have unique signaling capabilities
Journal of Immunology, ISSN: 15506606 00221767
Mary M. Tomayko; Shannon M. Anderson; Catherine E. Brayton; Saheli Sadanand; Natalie C. Steinel; Timothy W. Behrens; Mark J. Shlomchik
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Influence of race on tolerance of platinum-based chemotherapy and clinical outcomes in women with advanced and recurrent cervical cancer: a pooled analysis of 3 Gynecologic Oncology Group studies
American Journal of Obstetrics and Gynecology, ISSN: 00029378
Steven C. Plaxe; Sandra E. Brooks; Chunquiao Tian; Jeffrey D. Bloss; David H. Moore; Harry J. Long
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Neuromyelitis optica and the optic neuritis treatment trial - Reply
Archives of Neurology, ISSN: 15383687 00039942
Craig H. Smith
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Recognition of genetic factors influencing the progression of hepatitis C: Potential for personalized therapy
Molecular Diagnosis and Therapy, ISSN: 11771062
Julie R. Jonsson; David M. Purdie; Andrew D. Clouston; Elizabeth E. Powell
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A role of macrophage complement receptor crig in immune clearance and inflammation
Molecular Immunology, ISSN: 18729142 01615890
Jeannie Q. He; Wiesmann; Menno Van Lookeren Campagne
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Reversible self-association of a concentrated monoclonal antibody solution mediated by fab-fab interaction that impacts solution viscosity
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Sonoko Kanai; Jun Liu; Thomas W. Patapoff; Steven J. Shire
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Racial disparities in asthma-related health outcomes in severe or difficult-to-treat asthma
Annals of Allergy, Asthma and Immunology, ISSN: 15344436 10811206
Tmirah Haselkorn; June H. Lee; David R. Mink; Weiss
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Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus
Nature Genetics, ISSN: 15461718 10614036
Robert R. Graham; Chris Cotsapas; Leela R. L. Davies; Rachel Hackett; Christopher J. Lessard; Joanlise M. Leon; Noel Burtt; Candace Guiducci; Melissa Parkin; Casey Gates; Robert M. Plenge; Timothy W. Behrens; Joan E. Wither; John D. Rioux; Fortin; Deborah S. Cunninghame Graham; Andrew K. Wong; Timothy J. Vyse; Mark J. Daly; David Altshuler; Kathy L. Moser; Patrick M. Gaffney
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The safety of bone allografts used in dentistry: A review
Journal of the American Dental Association, ISSN: 00028177
Dan Holtzclaw; Nicholas Toscano; Lisa Eisenlohr; Don Callan
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The complex inter-relationships between protein flexibility and stability
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Tim J. Kamerzell; C. Russell Middaugh
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Anti-CD22-MCC-DM1 and MC-MMAF conjugates: Impact of assay format on pharmacokinetic parameters determination
Bioconjugate Chemistry, ISSN: 10431802
Jean-Philippe Stephan; Pamela Chan; Chien C. Lee; Nelson; J. Michael Elliott; Charity Bechtel; Helga Raab; David Xie; Jon Akutagawa; Jakub Baudys; Ola M. Saad; Saileta Prabhu; Wai Lee T. Wong; Richard L. Vandlen; Fred Jacobson; Allen Ebens
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15 Capillary electrophoresis and bioanalysis
Separation Science and Technology, ISSN: 01496395
Oscar Salas-Solano; Chantal Felten
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The Notch pathway in prostate development and cancer
Differentiation, ISSN: 14320436 03014681
Kevin G. Leong; Gao
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Evaluation of hydrate-screening methods
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Yonc Cui; Erica Yao
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Synthesis of a cross-bridged cyclam derivative for peptide conjugation and 64Cu radiolabeling
Bioconjugate Chemistry, ISSN: 10431802
C. Andrew Boswell; Celeste A. S. Regino; Kwamena E. Baidoo; Karen J. Wong; Ambika Bumb; Heng Xu; Diane E. Milenic; James A. Kelley; Christopher C. Lai; Martin W. Brechbiel
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Stopping replication, at the beginning
Nature Chemical Biology, ISSN: 15524469 15524450
Peter K Jackson
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Summary statement novel agents in the treatment of lung cancer: Fifth Cambridge conference assessing opportunities for combination therapy
Journal of Thoracic Oncology, ISSN: 15561380 15560864
Thomas J. Lynch; George R. Blumenschein; Jeff A. Engelman; Igor Espinoza-Delgado; Ramaswamy Govindan; Jeffrey H. Hanke; Nasser H. Hanna; John V. Heymach; Fred R. Hirsch; Pasi A. Jänne; Rogerio C. Lilenbaum; Ronald B. Natale; Gregory J. Riely; Lecia V. Sequist; Geoffrey I. Shapiro; Alice T. Shaw; Frances A. Shepherd; Mark A. Socinski; A Gregory Sorensen; Heather A. Wakelee; Aaron Weitzman
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Prediction of the possibility of the second peak of drug plasma concentration time curve after iv bolus administration from the standpoint of the traditional multi-compartmental linear pharmacokinetics
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Leonid M. Berezhkovskiy
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Ten-year outcomes following traumatic brain injury: A population-based cohort
Brain Injury, ISSN: 1362301X 02699052
Cameron; David M. Purdie; Kliewer; Rod J. McClure
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Ranibizumab Combined With Verteporfin Photodynamic Therapy in Neovascular Age-related Macular Degeneration (FOCUS): Year 2 Results
American Journal of Ophthalmology, ISSN: 00029394
Andrew N. Antoszyk; Lisa Tuomi; Carol Chung; Angele Singh
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Blockade of CD11a by efalizumab in psoriasis patients induces a unique state of T-cell hyporesponsiveness
Journal of Investigative Dermatology, ISSN: 15231747 0022202X
Emma Guttman-Yassky; Yulia Vugmeyster; Michelle A. Lowes; Francesca Chamian; Toyoko Kikuchi; Mark Kagen; Patricia Gilleaudeau; Edmund Lee; Brisdell Hunte; Howell; Wolfgang Dummer; Bodary; James G. Krueger
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A key claudin extracellular loop domain is critical for epithelial barrier integrity
American Journal of Pathology, ISSN: 00029440
Mrsny; G. Thomas Brown; Kirsten Gerner-Smidt; Andre G. Buret; Jon B. Meddings; Quan; Michael Koval; Asma Nusrat
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Ranibizumab for macular edema due to retinal vein occlusions: Implication of VEGF as a critical stimulator
Molecular Therapy, ISSN: 15250024 15250016
Peter A. Campochiaro; Gulnar Hafiz; Syed Mahmood Shah; Quan Dong Nguyen; Howard Ying; Diana V. Do; Edward Quinlan; Ingrid Zimmer-Galler; Julia A. Haller; Sharon D. Solomon; Jennifer U. Sung; Yasmin Hadi; Kashif A. Janjua; Nida Jawed; David F. Choy; Joseph R. Arron
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Insurance status and asthma-related health care utilization in patients with severe asthma
Annals of Allergy, Asthma and Immunology, ISSN: 10811206
Anju T. Peters; Julie C. Klemens; Tmirah Haselkorn; Weiss; Leslie C. Grammer; June H. Lee; Hubert Chen
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Assessing productivity loss and activity impairment in severe or difficult-to-treat asthma
Value in Health, ISSN: 15244733 10983015
Hubert Chen; Paul D. Blanc; Mary Lou Hayden; Eugene R. Bleecker; Chawla; June H. Lee
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Compliance and persistence in pediatric and adult patients receiving growth hormone therapy
Endocrine Practice, ISSN: 1530891X
Rosenfeld; Bert Bakker
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Recently-approved sapropterin reduces phenylalanine levels
Managed Care, ISSN: 10623388
Thomas Morrow
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T-cell lymphomas in T-cell-specific Pten-deficient mice originate in the thymus
Leukemia, ISSN: 14765551 08876924
Thijs Hagenbeek; Hergen Spits
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Long-term safety of recombinant human growth hormone in Turner syndrome
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X 0021972X
Katrina Bolar; Andrew R. Hoffman; Thomas J. Maneatis; Barbara M. Lippe
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Height velocity targets from the national cooperative growth study for first-year growth hormone responses in short children
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X 0021972X
Bert Bakker; James W. Frane; Henry Anhalt; Barbara M. Lippe; Rosenfeld
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Personalized medicine complicates medical decision-making
Managed Care, ISSN: 10623388
Thomas Morrow
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Randomized, Double-Masked, Sham-Controlled Trial of Ranibizumab for Neovascular Age-related Macular Degeneration: PIER Study Year 1
American Journal of Ophthalmology, ISSN: 00029394
Carl D. Regillo; David M. Brown; Prema Abraham; Huibin Yue; Tsontcho Ianchulev; Susan Schneider; Naveed Shams
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