Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 9551 - 9600 OF 15971 RESULTS

Long-term safety of recombinant human growth hormone in children
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X 0021972X
Jennifer J. Bell; Parker; Rita D. Swinford; Andrew R. Hoffman; Thomas J. Maneatis; Barbara M. Lippe
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Regulation of death receptor signaling by the ubiquitin system
Cell Death and Differentiation, ISSN: 13509047 14765403
Ingrid E. Wertz; Vishva M. Dixit
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Crystal structures of IL-2-inducible T cell kinase complexed with inhibitors: Insights into rational drug design and activity regulation
Chemical Biology and Drug Design, ISSN: 17470285 17470277
Alan K. Kutach; Armando G. Villaseñor; Diana Lam; Charles Belunis; Cheryl Janson; Stephen Lok; Li-Na Hong; Chao-Min Liu; Jerome Deval; Thomas J. Novak; Jim W. Barnett; Wei Chu; David Shaw; Andreas Kuglstatter
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Efficacy and safety of rituximab in moderately-to-severely active systemic lupus erythematosus: The randomized, double-blind, phase II/III systemic lupus erythematosus evaluation of rituximab trial
Arthritis and Rheumatism, ISSN: 00043591 15290131
Merrill; C. Michael Neuwelt; Daniel J. Wallace; Joseph C. Shanahan; Latinis; James C. Oates; Tammy O. Utset; Gordon; David A. Isenberg; Hsin-Ju Hsieh; David Zhang; Paul Brunetta
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Hijacking HES1: how tumors co-opt the anti-differentiation strategies of quiescent cells
Trends in Molecular Medicine, ISSN: 14714914
Liyun Sang; James M. Roberts; Hilary A. Coller
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Poor disease control among insured users of high-dose combination therapy for asthma
Allergy and Asthma Proceedings, ISSN: 10885412 15396304
Michael S. Broder; Eunice Chang; Tripthi V. Kamath; Sandhya Sapra
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Purification and characterization of a motility initiating protein from caprine epididymal plasma
Journal of Cellular Physiology, ISSN: 00219541
Bijay S. Jaiswal; Kaushik Das; Sudipta Saha; Sandhya Rekha Dungdung; Gopal C. Majumder
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AF-353, a novel, potent and orally bioavailable P2X3/P2X2/3 receptor antagonist
British Journal of Pharmacology, ISSN: 14765381 00071188
Joel R. Gever; Rothschild Soto; Robert A. Henningsen; Renee S. Martin; David Hackos; Sandip Panicker; Rubas; Ian B. Oglesby; Michael P. Dillon; Marcos E. Milla; Geoffrey Burnstock; Anthony P. D. W. Ford
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Local tissue distribution and cellular fate of vascular endothelial growth factor (VEGF) following intramuscular injection
Journal of Drug Targeting, ISSN: 1061186X 10292330
Daugherty; Mrsny
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Structural characterization of intact antibodies by high-resolution LTQ Orbitrap mass spectrometry
Journal of Mass Spectrometry, ISSN: 10765174 10969888
Jennifer Zhang; Hongbin Liu; Viswanatham Katta
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Mechanism-based receptor-binding model to describe the pharmacokinetic and pharmacodynamic of an anti-α5β1 integrin monoclonal antibody (volociximab) in cancer patients
Cancer Chemotherapy and Pharmacology, ISSN: 03445704
Chee Ng; Shuang Bai; Takimoto; Meina Tao Tang; Anthony W. Tolcher
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Prospects for personalized medicine with inhibitors targeting the RAS and PI3K pathways
Expert Review of Molecular Diagnostics, ISSN: 14737159 17448352
Lackner
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Cell culture monitoring via an auto-sampler and an integrated multi-functional off-line analyzer
Biotechnology Progress, ISSN: 87567938 15206033
Gayle E. Derfus; Daniel Abramzon; Meg Tung; David Chang; Robert Kiss; Ashraf Amanullah
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Guidelines for reporting the use of capillary electrophoresis in proteomics
Nature Biotechnology, ISSN: 15461696 10870156
Paula J. Domann; Satoko Akashi; Coral Barbas; Lihua Huang; Wendy Lau; Cristina Legido-Quigley; Stephen McClean; Christian Neusü; David Perrett; Milena Quaglia; Erdmann Rapp; Lance Smallshaw; Norman W. Smith; W Franklin Smyth; Chris Taylor
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Phase 1 study of aflibercept administered subcutaneously to patients with advanced solid tumors
Clinical Cancer Research, ISSN: 10780432
William P. Tew; Michael S. Gordon; John Murren; Jakob Dupont; Sandra Pezzulli; Carol Aghajanian; Paul Sabbatini; David Mendelson; Lawrence Schwartz; Scott Gettinger; Amanda Psyrri; Jesse M. Cedarbaum; David R. Spriggs
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Immunization responses in rheumatoid arthritis patients treated with rituximab: Results from a controlled clinical trial
Arthritis and Rheumatism, ISSN: 00043591 15290131
Bingham; R. John Looney; Deodhar; Neal Halsey; Maria Greenwald; Christine Codding; Benjamin L. Trzaskoma; Flavius Martin; Sunil Agarwal; Ariella Kelman
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A two-stage algorithm for designing phase I cancer clinical trials for two new molecular entities
Contemporary Clinical Trials, ISSN: 15517144
Zheng Su
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B-cell activation influences T-cell polarization and outcome of anti-CD20 B-cell depletion in central nervous system autoimmunity
Annals of Neurology, ISSN: 15318249 03645134
Martin Weber; Thomas Prod'homme; Juan C. Patarroyo; Nicolas Molnarfi; Tara Karnezis; Klaus Lehmann-Horn; Dimitry Danilenko; Jeffrey Eastham-Anderson; Anthony J. Slavin; Christopher Linington; Claude C.A. Bernard; Flavius Martin; Scott S. Zamvil
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The conserved bardet-biedl syndrome proteins assemble a coat that traffics membrane proteins to Cilia
Cell, ISSN: 00928674
Hua Jin; Susan Roehl White; Toshinobu Shida; Stefan Schulz; Mike Aguiar; Steven P. Gygi; J.Fernando Bazan; Maxence V. Nachury
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Inflammasome-dependent release of the alarmin HMGB1 in endotoxemia
Journal of Immunology, ISSN: 15506606 00221767
Lamkanfi; Anasuya Sarkar; Vande Walle; Alberto C. Vitari; Amal O. Amer; Mark D. Wewers; Kevin J. Tracey; Thirumala-Devi Kanneganti; Vishva M. Dixit
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Pharmaceutical medical information contact centers: Results of three benchmarking surveys
Drug Information Journal, ISSN: 00928615
Pete Guillot; Stacey M. Fung
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Semi-automated protein binding methodology using equilibrium dialysis and a novel mixed-matrix cassette approach
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Emile G. Plise; Daniel Tran; Laurent Salphati
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Factors affecting the viscosity in high concentration solutions of different monoclonal antibodies
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Sandeep Yadav; Steven J. Shire; Devendra S. Kalonia
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Standardizing rodent trimming and embedding guidelines for histology: Improving efficiency in the laboratory
Journal of Histotechnology, ISSN: 01478885
Monika Larson; Taylor; Marjie Van Hoy
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Surface expression of precursor N-cadherin promotes tumor cell invasion
Neoplasia (United States), ISSN: 14765586 15228002
Deborah Maret; Eugenia Gruzglin; Mohamad Seyed Sadr; Vincent Siu; Shan; Alexander W. Koch; Nabil G. Seidah; Rolando F. del Maestro; David R. Colman
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Molecular mechanisms of regulatory T cell development and suppressive function
Progress in Molecular Biology and Translational Science, ISSN: 18771173
Kim
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Cell biology redux.
Molecular Biology of the Cell, ISSN: 19394586
Ira Mellman
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Molecular biomarker analyses using circulating tumor cells
PLoS ONE, ISSN: 19326203
Elizabeth A. Punnoose; Siminder Atwal; Jill M. Spoerke; Heidi Savage; Ajay Pandita; Ru-Fang Yeh; Andrea Pirzkall; Bernard M. Fine; Lukas Amler; Daniel S. Chen; Lackner
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Questions about coverage accompany new fully implantable hearing system
Managed Care, ISSN: 10623388
Thomas Morrow
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On the possibility of self-induction of drug protein binding
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Leonid M. Berezhkovskiy
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Randomized, double-masked, sham-controlled trial of ranibizumab for neovascular age-related macular degeneration: PIER study year 2
American Journal of Ophthalmology, ISSN: 00029394
Prema Abraham; Huibin Yue; Laura J. Wilson
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Structure of the Complex between HER2 and an Antibody Paratope Formed by Side Chains from Tryptophan and Serine
Journal of Molecular Biology, ISSN: 00222836
Robert D. Fisher; Ultsch; Andreas Lingel; Gabriele Schaefer; Lily Shao; Sara Birtalan; Sachdev S. Sidhu; Eigenbrot
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Effect of temperature, pH, dissolved oxygen, and hydrolysate on the formation of triple light chain antibodies in cell culture.
Biotechnology Progress, ISSN: 15206033
Natalia Gomez; Jun Ouyang; Mary D. H. Nguyen; Abigail R Vinson; Andy Lin; Inn H. Yuk
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Monoclonal antibody purification using cationic polyelectrolytes: an alternative to column chromatography.
Biotechnology Progress, ISSN: 15206033
Thanmaya Peram; Paul McDonald; Jayme N. Carter-Franklin; Fahrner
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Treatment outcomes by tumor histology in eastern cooperative group study E4599 of bevacizumab with paclitaxel/carboplatin for advanced non-small cell lung cancer
Journal of Thoracic Oncology, ISSN: 15561380 15560864
Alan Sandler; Jing Yi; Suzanne Dahlberg; Margaret M. Kolb; Lisa I. Wang; Julie Hambleton; Joan H. Schiller; David H. Johnson
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Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency
Nature Genetics, ISSN: 15461718 10614036
Ricardo C. Ferreira; Qiang Pan-Hammarström; Robert R. Graham; Vesela Gateva; Gumersindo Fontán; Annette T. Lee; Ward Ortmann; Elena Urcelay; Miguel Fernández-Arquero; Concepción Núñez; Gudmundur Jorgensen; Björn R. Ludviksson; Sinikka Koskinen; Katri Haimila; Hilary F. Clark; Lars Klareskog; Peter K. Gregersen; Timothy W. Behrens; Lennart Hammarström
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Anti-CD22-MCC-DM1: An antibody-drug conjugate with a stable linker for the treatment of non-Hodgkin's lymphoma
Leukemia, ISSN: 14765551 08876924
Andrew G. Polson; Marna Williams; Gray; Reina N. Fuji; Kirsten Achilles Poon; Jacqueline McBride; Helga Raab; Thomas Januario; MaryAnn Go; Jeffrey Lau; Shang-Fan Yu; Du; Franklin Fuh; Christine Tan; Yan Wu; Wei-Ching Liang; Saileta Prabhu; Jean-Philippe Stephan; Hongo; Randall Dere; Rong Deng; Cullen; Ruth De Tute; Bennett; Andy Rawstron; Andrew S. Jack; Allen Ebens
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Characterization of a nutrient feed precipitate from an E. coli fermentation process.
Biotechnology Progress, ISSN: 15206033
Lauren Speciner; Erin Mallon; Susan Leung; Mike Laird; Osigwe Esue
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RTM3, which controls long-distance movement of potyviruses, is a member of a new plant gene family encoding a meprin and TRAF homology domain-containing protein
Plant Physiology, ISSN: 15322548 00320889
Patrick Cosson; Luc Sofer; Quang Hien Le; Valérie Léger; Valérie Schurdi-Levraud; Steven A. Whitham; Miki L. Yamamoto; Suresh Gopalan; Olivier le Gall; Thierry Candresse; James C. Carrington; Frédéric Revers
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Noncompartmental kinetic analysis of DCE-MRI data from malignant tumors: Application to glioblastoma treated with bevacizumab
Magnetic Resonance in Medicine, ISSN: 15222594 07403194
Ruediger E. Port; Lisa J. Bernstein; Daniel P. Barboriak; Lu Xu; Timothy P.L. Roberts; Nicholas Van Bruggen
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Vascular endothelial growth factor and age-related macular degeneration: From basic science to therapy
Nature Medicine, ISSN: 1546170X 10788956
Napoleone Ferrara
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Molecular dynamics simulations of hydrotropic solubilization and self-aggregation of nicotinamide
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Yong Cui; Chenyue Xing; Yingqing Ran
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The chemical toolbox for monitoring protein fatty acylation and prenylation
Nature Chemical Biology, ISSN: 15524469 15524450
Rami N. Hannoush; Jinglucy Sun
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O-fucose modulates notch-controlled blood lineage commitment
American Journal of Pathology, ISSN: 15252191 00029440
Quanjian Yan; David Yao; Lebing L. Wei; Yuanshuai Huang; Jay Myers; Lihua Zhang; Wei Xin; Jeongsup Shim; Yunfang Man; Bronislawa Petryniak; Stanton Gerson; John Lowe; Lan Zhou
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Incidence of New Choroidal Neovascularization in Fellow Eyes of Patients Treated in the MARINA and ANCHOR Trials
American Journal of Ophthalmology, ISSN: 00029394
Irene Barbazetto; Namrata Saroj; Howard Shapiro; Pamela Wong; Allen C. Ho; K. Bailey Freund
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Ranibizumab for Macular Edema following Central Retinal Vein Occlusion. Six-Month Primary End Point Results of a Phase III Study
Ophthalmology, ISSN: 01616420
David M. Brown; Peter A. Campochiaro; Rishi Singh; Zhengrong Li; Sarah Gray; Namrata Saroj; Amy Chen Rundle; Roman G. Rubio; Wendy Yee Murahashi
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Early menstrual characteristics associated with subsequent diagnosis of endometriosis
American Journal of Obstetrics and Gynecology, ISSN: 00029378
Susan A. Treloar; Tanya A. Bell; Christina M. Nagle; David M. Purdie; Adèle C. Green
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Ranibizumab for Macular Edema following Branch Retinal Vein Occlusion. Six-Month Primary End Point Results of a Phase III Study
Ophthalmology, ISSN: 01616420
Peter A. Campochiaro; Jeffrey S. Heier; Leonard Feiner; Sarah Gray; Namrata Saroj; Amy Chen Rundle; Wendy Yee Murahashi; Roman G. Rubio
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Vessel imaging with viable tumor analysis for quantification of tumor angiogenesis
Magnetic Resonance in Medicine, ISSN: 15222594 07403194
Sharon E. Ungersma; Glenn Pacheco; Calvin Ho; Sharon Fong Yee; Ross; Nicholas Van Bruggen; Franklin V. Peale Jr.; Ross; Richard A. D. Carano
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Manipulation of host cell death pathways during microbial infections
Cell Host and Microbe, ISSN: 19346069 19313128
Lamkanfi; Vishva M. Dixit
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