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Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 9701 - 9750 OF 15491 RESULTS

Molecular imaging in drug development
Nature Reviews Drug Discovery, ISSN: 14741776 14741784
Jürgen K. Willmann; Nicholas Van Bruggen; Ludger M. Dinkelborg; Sanjiv S. Gambhir
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The effects of anesthetic agent and carrier gas on blood glucose and tissue uptake in mice undergoing dynamic FDG-PET Imaging: Sevoflurane and Isoflurane Compared in Air and in Oxygen
Molecular Imaging and Biology, ISSN: 15361632 18602002
Judith E. Flores; Leanne McFarland; Alexander N. Vanderbilt; Annie Ogasawara; Simon P. Williams
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Functional genomics identifies ABCC3 as a mediator of taxane resistance in HER2-amplified breast cancer
Cancer Research, ISSN: 00085472
Carol O'Brien; Guy Cavet; Ajay Pandita; Xiaolan Hu; Lauren Haydu; Sankar Mohan; Toy; Rivers; Zora Modrusan; Lukas Amler; Lackner
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3D micro-CT imaging of the postmortem brain
Journal of Neuroscience Methods, ISSN: 01650270
De Crespigny; Hani Bou-Reslan; Merry C. Nishimura; Phillips; Richard A. D. Carano; Helen D'Arceuil
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DSCAM Is a Netrin Receptor that Collaborates with DCC in Mediating Turning Responses to Netrin-1
Cell, ISSN: 00928674
Alice Ly; Anatoly Nikolaev; Geetha Suresh; Yufang Zheng; Marc Tessier-Lavigne; Elke Stein
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Aurora A: Target Invalidated?
Chemistry and Biology, ISSN: 10745521
Andrea G Cochran
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Molecular mechanisms controlling midline crossing by precerebellar neurons
Journal of Neuroscience, ISSN: 02706474 02706474
Thomas Di Meglio; Kim T. Nguyen-Ba-Charvet; Marc Tessier-Lavigne; Constantino Sotelo; Alain Chedotal
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DEAF-1 regulates immunity gene expression in Drosophila
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424 10916490
Darien E. Reed; Xinhua M. Huang; James A. Wohlschlegel; Michael Levine; Kate Senger
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Final survival and safety results from a multicenter, open-label, phase 3b trial of erlotinib in patients with advanced nonsmall cell lung cancer
Cancer, ISSN: 0008543X 10970142
David Spigel; Ming Lin; Vincent O'Neill; John Hainsworth
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Improvement in patient-reported outcomes in a rituximab trial in patients with severe rheumatoid arthritis refractory to anti-tumor necrosis factor therapy
Arthritis Care and Research, ISSN: 21514658
Edward Keystone; Gerd R. Burmester; Richard A. Furie; James E. Loveless; Paul Emery; Joel M. Kremer; Paul P. Tak; Michael S. Broder; Elaine B. Yu; Matthew W. Cravets; Fabio Magrini; Jost
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Bridging Toll-like- and B Cell-Receptor Signaling: Meet Me at the Autophagosome
Immunity, ISSN: 10747613
John G. Monroe; Mary E. Keir
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Systems analysis of quantitative shRNA-library screens identifies regulators of cell adhesion
BMC Systems Biology, ISSN: 17520509
Xiaodong Huang; Jean Y.J. Wang; Xin Lu
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Genomic analysis of Drosophila neuronal remodeling: A role for the RNA-binding protein boule as a negative regulator of axon pruning
Journal of Neuroscience, ISSN: 02706474 02706474
Eric D. Hoopfer; Andrea Penton; Ryan J. Watts; Liqun Luo
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Dual-specificity phosphatases in the hypo-osmotic stress response of keratin-defective epithelial cell lines
Experimental Cell Research, ISSN: 00144827
Mirjana Liovic; Brian Lee; Marjana Tomic-Canic; Mariella D'Alessandro; Viacheslav N. Bolshakov; E. Birgitte Lane
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Dual-specificity phosphatases in the hypo-osmotic stress response of keratin-defective epithelial cell lines
Experimental Cell Research, ISSN: 00144827
Mirjana Liovic; Brian B. Lee; Marjana Tomic-Canic; Mariella D'Alessandro; Viacheslav N. Bolshakov; E. Birgitte Lane
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A NOD2-NALP1 complex mediates caspase-1-dependent IL-1β secretion in response to Bacillus anthracis infection and muramyl dipeptide
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424 10916490
Li-Chung Hsu; Syed R. Ali; Shauna McGillivray; Ping-Hui Tseng; Sanjeev Mariathasan; Eric W. Humke; Lars Eckmann; Jonathan J. Powell; Victor Nizet; Vishva M. Dixit; Michael Karin
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To kill a tumor cell: The potential of proapoptotic receptor agonists
Journal of Clinical Investigation, ISSN: 00219738 15588238
Avi Ashkenazi; Roy S. Herbst
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Use of quantitative pharmacology in the development of HAE1, a high-affinity anti-ige monoclonal antibody
AAPS Journal, ISSN: 15507416
Wendy Putnam; Jing Li; Jonas Haggstrom; Chee Ng; Saloumeh Kadkhodayan Fischer; Melissa Cheu; Yamo Deniz; Henry B. Lowman; Fielder; Jennifer Visich; Amita Joshi; Nelson L'ntshotsholé Jumbe
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Targeting the extrinsic apoptosis pathway in cancer
Cytokine and Growth Factor Reviews, ISSN: 13596101
Avi Ashkenazi
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Netrin-1 inhibits sprouting angiogenesis in developing avian embryos
Developmental Biology, ISSN: 00121606
Karine Bouvrée; Bruno Larrivee; Xiang Lv; Li Yuan; Benjamin DeLafarge; Catarina Freitas; Thomas Mathivet; Christiane Bréant; Marc Tessier-Lavigne; Andréas Bikfalvi; Anne Eichmann; Luc Pardanaud
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Role of P-glycoprotein and the intestine in the excretion of DPC 333 [(2R)-2-{(3R)-3-amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl] -2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in rodents
Drug Metabolism and Disposition, ISSN: 00909556 1521009X
C. Edwin Garner; Eric G. Solon; Chii-Ming Lai; Jianrong Lin; Gang Luo; Kevin Jones; Jingwu Duan; Carl P. Decicco; Thomas Maduskuie; Stephen E. Mercer; Lian-Shen Gan; Mingxin Qian; Shimoga Prakash; Huey-Shin Shen; Frank W. Lee
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MetMAb, the one-armed 5d5 anti-c-met antibody, inhibits orthotopic pancreatic tumor growth and improves survival
Cancer Research, ISSN: 00085472
Hongkui Jin; Renhui Yang; Zhong Zheng; Mally Romero; Ross; Hani Bou-Reslan; Richard A. D. Carano; Ian Kasman; Elaine Mai; Judy Young; Jiping Zha; Zemin Zhang; Ross; Ralph H. Schwall; Gail T. Colbern; Mark Merchant
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(Un)expected roles of c-IAPs in apoptotic and NFκB signaling pathways
Cell Cycle, ISSN: 15514005 15384101
Eugene Varfolomeev; Domagoj Vucic
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Multiple sclerosis risk after optic neuritis: Final optic neuritis treatment trial follow-up
Archives of Neurology, ISSN: 00039942 15383687
Michael Brodsky; Sarkis Nazarian; Silvia Orengo-Nania; George J. Hutton; Edward G. Buckley; E. Wayne Massey; M. Tariq Bhatti; Melvin Greer; James Goodwin; Michael Wall; Peter J. Savino; Thomas Leist; Neil R. Miller; David Irani; Jonathan D. Trobe; Wayne Cornblath; David I. Kaufman; Eric Eggenberger; Mark J. Kupersmith; William T. Shults; Leslie McAllister; Steve Hamilton; Roy W. Beck; Mariya Dontchev; Robin L. Gal; Craig Kollman; John L. Keltner; Craig H. Smith
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Ubiquitin-mediated regulation of TNFR1 signaling
Cytokine and Growth Factor Reviews, ISSN: 13596101
Ingrid E. Wertz; Vishva M. Dixit
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Quantitative determination of humanized monoclonal antibody rhuMAb2H7 in cynomolgus monkey serum using a Generic Immunoglobulin Pharmacokinetic (GRIP) assay
Journal of Immunological Methods, ISSN: 00221759
Yang; Carl Ng; Henry B. Lowman; Chestnut; Cheryl A. Schofield; Bryan Sandlund; James A. Ernst; Bennett; Quarmby
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Dendritic cells: Driving the differentiation programme of T cells in viral infections
Immunology and Cell Biology, ISSN: 08189641 14401711
Frederick Masson; Adele Mount; Nicholas S. Wilson; Gabrielle T Belz
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High-resolution genomic and expression analyses of copy number alterations in breast tumors
Genes Chromosomes and Cancer, ISSN: 10452257 10982264
Matthias Peter; Jane Fridlyand; Li Li; Gad Getz; Rameen Beroukhim; Scott Lohr; Thomas D Wu; Guy Cavet; Zemin Zhang; John Chant
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Design opportunities for actively targeted nanoparticle vaccines
Nanomedicine, ISSN: 17435889
Tarek M. Fahmy; Stacey L. Demento; Michael J. Caplan; Ira Mellman; W. Mark Saltzman
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Vascular endothelial growth factors in pulmonary edema: An update
Journal of Thrombosis and Thrombolysis, ISSN: 09295305
Ioanna Kosmidou; Dimitrios Karmpaliotis; Ajay J. Kirtane; Hal V. Barron; C.Michael Gibson
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A golden era of opportunity in immunotherapy discovery and development
Immunological Reviews, ISSN: 01052896 1600065X
Andrew A. Chan
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PCSK9 function and physiology
Journal of Lipid Research, ISSN: 00222275 15397262
Andrew S. Peterson; Loren G. Fong; Stephen G. Young
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Proteins and Peptides as Drugs: Sources and Methods of Purification
Biotechnology: Second, Completely Revised Edition,
Stuart E. Builder; Robert L. Garnick; James C. Hodgdon; John R. Ogez
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In vitro Protein Refolding
Biotechnology: Second, Completely Revised Edition,
Cleland; Daniel I. C. Wang
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IgG regulates the CD1 expression profile and lipid antigen-presenting function in human dendritic cells via RrγRIIa
Blood, ISSN: 15280020 00064971
Anna Smed-Sörensen; Markus Moll; Tan-Yuri Cheng; Karin Loré; Anna-Carin Norlin; Leif Perbeck; D. Branch Moody; Anna-Lena Spetz; Johan K. Sandberg
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On-line CE-LIF-MS technology for the direct characterization of N-linked glycans from therapeutic antibodies
Analytical Chemistry, ISSN: 00032700
Lynn Gennaro; Oscar Salas-Solano
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Regulation of epithelial branching morphogenesis and cancer cell growth of the prostate by Wnt signaling
PLoS ONE, ISSN: 19326203
Bu-Er Wang; Xi-De Wang; James A. Ernst; Paul G. Polakis; Gao
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The hominoid-specific oncogene TBC1d3 activates ras and modulates epidermal growth factor receptor signaling and trafficking
Journal of Biological Chemistry, ISSN: 00219258 1083351X
Marisa J. Wainszelbaum; Audra J. Charron; Chen Kong; Donald S. Kirkpatrick; Priya Srikanth; M. Alejandro Barbieri; Steven P. Gygi; Philip D. Stahl
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Alternative Splicing of the Robo3 Axon Guidance Receptor Governs the Midline Switch from Attraction to Repulsion
Neuron, ISSN: 08966273
Zhe Chen; Bryan B. Gore; Hua Long; Le Ma; Marc Tessier-Lavigne
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In vitro Protein Refolding
Biotechnology: Second, Completely Revised Edition,
Cleland; Daniel I. C. Wang
View on Scopus
Proteins and Peptides as Drugs: Sources and Methods of Purification
Biotechnology: Second, Completely Revised Edition,
Stuart E. Builder; Robert L. Garnick; James C. Hodgdon; John R. Ogez
View on Scopus
Manufacturing control systems bridge production and IT
Control Engineering, ISSN: 00108049
Ronald E. Menéndez; Darrell Tanner
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Specificity of the STAT4 genetic association for severe disease manifestations of systemic lupus erythematosus
PLoS Genetics, ISSN: 15537390 15537404
Kimberly E. Taylor; Elaine F. Remmers; Annette T. Lee; Ward Ortmann; Robert M. Plenge; Tian; Sharon A. Chung; Joanne Nititham; Geoffrey Hom; Amy H. Kao; F. Yesim Demirci; M. Ilyas Kamboh; Michelle Petri; Manzi; Daniel L. Kastner; Michael F. Seldin; Peter K. Gregersen; Timothy W. Behrens; Lindsey A. Criswell
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Role of FDA's drug information centers
American Journal of Health-System Pharmacy, ISSN: 10792082
Kavita C. Dada; Mary Kremzner; Sanjeev K. Bhanot; Renu Lal
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Change in serum measurements of cartilage oligomeric matrix protein and association with the development and worsening of radiographic hip osteoarthritis
Osteoarthritis and Cartilage, ISSN: 10634584
Chaganti; Ariella Kelman; Lui; Yao; Javaid; Bauer; Nevitt; Lane; for the Study of Osteoporotic Fractures Research Group (SOF)
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Purifying therapeutic monoclonal antibodies
Chemical Engineering Progress, ISSN: 03607275
Amit Mehta; Martha Lovato Tse; Jace Fogle; Amy Len; Roshan Shrestha; Nuno Fontes; Lebreton; Bradley Wolk; Robert Van Reis
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Microphthalmia-associated transcription factor is a critical transcriptional regulator of melanoma inhibitor of apoptosis in melanomas
Cancer Research, ISSN: 00085472
Jasmin N. Dynek; Sara M. Chan; Jinfeng Liu; Jiping Zha; Wayne J. Fairbrother; Domagoj Vucic
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The nucleolar phosphatase Cdc14B is dispensable for chromosome segregation and mitotic exit in human cells
Cell Cycle, ISSN: 15514005 15384101
Eli Berdougo; Maxence V. Nachury; Peter K Jackson; Prasad V. Jallepalli
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An actively mixed mini-bioreactor for protein production from suspended animal cells
Biotechnology and Bioengineering, ISSN: 00063592 10970290
Jinpian Diao; Lincoln Young; Peng Zhou; Michael L. Shuler
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Role of haptoglobin on the uptake of native and β-chain [trimesoyl-(Lys82)β-(Lys82)β] cross-linked human hemoglobins in isolated perfused rat livers
Drug Metabolism and Disposition, ISSN: 00909556 1521009X
Edwin C. Y. Chow; Lichuan Liu; Noam Ship; Ronald H. Kluger; K. Sandy Pang
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