Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 9751 - 9800 OF 15217 RESULTS

September 1, 2007

Macrophage complement receptors and pathogen clearance

Cellular Microbiology, ISSN: 14625814 14625822

Menno Van Lookeren Campagne; Wiesmann; Eric J. Brown

September 1, 2007

Highly efficient somatic-mutation identification using Escherichia coli mismatch-repair detection

Nature Methods, ISSN: 15487091 15491676

Brock A. Peters; Zhengyan Kan; Dragan Sebisanovic; Kanan Pujara; Zhiyong Wang; Peter Hong; Bernard Chow; Stinson; Victoria E. H. Carlton; Thinh Q. Pham; Howard M. Stern; Waring; Kenneth J. Hillan; Eberhard; Frederic J. De Sauvage; Jianbiao Zheng; Malek Faham; Somasekar Seshagiri

August 30, 2007

Isolation, growth and differentiation of hair cell progenitors from the newborn rat cochlear greater epithelial ridge

Journal of Neuroscience Methods, ISSN: 01650270

Yuan Zhang; Suo-qiang Zhai; Shou; Wei Song; Jian-he Sun; Wei Guo; Gui-liang Zheng; Yin-yan Hu; Gao

August 28, 2007

Molecular characterization of Rab11-FIP3 binding to ARF GTPases

European Journal of Cell Biology, ISSN: 01719335

Eric Schonteich; Manohar Pilli; Glenn C. Simon; Hugo T. Matern; Jagath R. Junutula; Danielle Sentz; Randall K. Holmes; Rytis Prekeris

August 28, 2007

Cortical dysplasia and skull defects in mice with a Foxc1 allele reveal the role of meningeal differentiation in regulating cortical development

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Konstantinos Zarbalis; Julie A. Siegenthaler; Youngshik Choe; Scott R. May; Andrew S. Peterson; Samuel J. Pleasure

August 24, 2007

Autocrine VEGF Signaling Is Required for Vascular Homeostasis

Cell, ISSN: 00928674

Sunyoung Lee; Tom T. Chen; Chad L. Barber; Maria C. Jordan; Jared Murdock; Sharina Desai; Napoleone Ferrara; Andras Nagy; Kenneth P. Roos; M. Luisa Iruela-Arispe

August 24, 2007

A Bacterial Effector Targets Mad2L2, an APC Inhibitor, to Modulate Host Cell Cycling

Cell, ISSN: 00928674

Hiroki Iwai; Minsoo Kim; Yuko Yoshikawa; Hiroshi Ashida; Michinaga Ogawa; Yukihiro Fujita; Daniel Muller; Teruo Kirikae; Peter K Jackson; Shuji Kotani; Chihiro Sasakawa

August 24, 2007

Blue-light-activated histidine kinases: Two-component sensors in bacteria

Science, ISSN: 00368075 10959203

Trevor E. Swartz; Tong-Seung Tseng; Marcus A. Frederickson; Gaston Paris; Diego J. Comerci; Gireesh Rajashekara; Jung-Gun Kim; Mary Beth Mudgett; Gary A. Splitter; Rodolfo A. Ugalde; Fernando A. Goldbaum; Winslow R. Briggs; Roberto A. Bogomolni

August 17, 2007

Dual regulation of SIRP α phosphorylation by integrins and CD47

Journal of Biological Chemistry, ISSN: 00219258 1083351X

Mette L. Johansen; Eric J. Brown

August 17, 2007

Neuropilin-1 binds to VEGF121 and regulates endothelial cell migration and sprouting

Journal of Biological Chemistry, ISSN: 00219258 1083351X

Qi Pan; Yvan Chathery; Yan Wu; Nisha Rathore; Raymond K. Tong; Franklin V. Peale Jr.; Anil Bagri; Marc Tessier-Lavigne; Alexander W. Koch; Ryan J. Watts

August 16, 2007

Retrograde BMP Signaling Regulates Trigeminal Sensory Neuron Identities and the Formation of Precise Face Maps

Neuron, ISSN: 08966273

Liberty K. Hodge; Matthew P. Klassen; Bao-Xia Han; Glenn Yiu; Joanna Hurrell; Audrey Howell; Guy Rousseau; Frederic Lemaigre; Marc Tessier-Lavigne; Fan Wang

August 15, 2007

Arterial thromboembolic events in patients with metastatic carcinoma treated with chemotherapy and bevacizumab

Journal of the National Cancer Institute, ISSN: 00278874 14602105

Frank A. Scappaticci; Jamey R. Skillings; Scott N. Holden; Hans-Peter Gerber; Kathy Miller; Fairooz F. Kabbinavar; Emily Bergsland; James Ngai; Holmgren; Jiuzhou Wang; Herbert Hurwitz

August 3, 2007

DNA internalized via caveolae requires microtubule-dependent, Rab7-independent transport to the late endocytic pathway for delivery to the nucleus

Journal of Biological Chemistry, ISSN: 00219258 1083351X

Athena W. Wong; Suzie J. Scales; Dorothea Reilly

August 3, 2007

Private lives: Reflections and challenges in understanding the cell biology of the immune system

Science, ISSN: 00368075 10959203

Ira Mellman

August 1, 2007

A mycobacterium ESX-1-secreted virulence factor with unique requirements for export

PLoS Pathogens, ISSN: 15537366 15537374

Bryant McLaughlin; Janet S. Chon; Jason A. MacGurn; Fredric Carlsson; Terri L. Cheng; Jeffery S. Cox; Eric J. Brown

August 1, 2007

Mode-of-action framework for evaluating the relevance of rodent forestomach tumors in cancer risk assessment

Toxicological Sciences, ISSN: 10966080 10960929

Deborah M. Proctor; Nicole M. Gatto; Sandra J. Hong; Krishna P. Allamneni

August 1, 2007

Phage display for engineering and analyzing protein interaction interfaces

Current Opinion in Structural Biology, ISSN: 0959440X

Sachdev S. Sidhu; Shohei Koide

August 1, 2007

Randomized comparison of phone versus in-person BRCA1/2 predisposition genetic test result disclosure counseling

Genetics in Medicine, ISSN: 10983600

Jean Jenkins; Kathleen A. Calzone; Eileen Dimond; David J. Liewehr; Seth M. Steinberg; Oxana Jourkiv; Pam Klein; Peter W. Soballe; Sheila A. Prindiville; Ilan R. Kirsch

August 1, 2007

Epidermal growth factor receptor in osteosarcoma: expression and mutational analysis

Human Pathology, ISSN: 00468177

Yong Hannah Wen; Koeppen; Roberto Garcia; Luis Chiriboga; Branden D. Tarlow; Brock A. Peters; Eigenbrot; Herman Yee; German Steiner; M. Alba Greco

August 1, 2007

Asthma control, severity, and quality of life: Quantifying the effect of uncontrolled disease

Journal of Allergy and Clinical Immunology, ISSN: 00916749

Hubert Chen; Michael K. Gould; Paul D. Blanc; Dave P. Miller; Tripthi V. Kamath; June H. Lee; Sean D. Sullivan

August 1, 2007

6-Hydroxybuspirone is a major active metabolite of buspirone: Assessment of pharmacokinetics and 5-hydroxytryptamine1A receptor occupancy in rats

Drug Metabolism and Disposition, ISSN: 00909556 1521009X

Harvey Wong; Randy C. Dockens; Lori Pajor; Suresh Yeola; James E. Grace Jr.; Arlene D. Stark; Rebecca A. Taub; Frank D. Yocca; Robert C. Zaczek; Yu-Wen Li

August 1, 2007

Sequential loss of tumor vessel pericytes and endothelial cells after inhibition of platelet-derived growth factor B by selective aptamer AX102

Cancer Research, ISSN: 00085472

Barbara Sennino; Beverly L. Falcón; Dilara McCauley; Tom Le; Thomas McCauley; Jeffrey C. Kurz; Amy Haskell; David M. Epstein; Donald M. McDonald

August 1, 2007

Tumor refractoriness to anti-VEGF treatment is mediated by CD11b +Gr1+ myeloid cells

Nature Biotechnology, ISSN: 10870156 15461696

Farbod Shojaei; Xiumin Wu; Ajay K. Malik; Cuiling Zhong; Megan E. Baldwin; Stefanie Schanz; Fuh; Hans-Peter Gerber; Napoleone Ferrara

August 1, 2007

Evaluation of assay technologies for the identification of protein-peptide interaction antagonists

Assay and Drug Development Technologies, ISSN: 1540658X

Saloumeh Kadkhodayan Fischer; Linda O. Elliott; Grace Mausisa; Heidi J. A. Wallweber; Deshayes; Bainian Feng; Wayne J. Fairbrother

August 1, 2007

Acute Reperfusion Therapy in ST-Elevation Myocardial Infarction from 1994-2003

American Journal of Medicine, ISSN: 00029343

Brahmajee K. Nallamothu; Martha Blaney; Susan M. Morris; Lori Parsons; Dave P. Miller; John G. Canto; Hal V. Barron; Harlan M. Krumholz

August 1, 2007

Computational approach to site-directed ligand discovery

Proteins: Structure, Function and Bioinformatics, ISSN: 08873585 10970134

Gergely Tóth; Kiran Mukhyala; James A. Wells

August 1, 2007

Novel leverage of structural genomics [5]

Nature Biotechnology, ISSN: 10870156 15461696

Jinfeng Liu; Gaetano T Montelione; Burkhard Rost

August 1, 2007

Kinetics of valproic acid glucuronidation: Evidence for in vivo autoactivation

Drug Metabolism and Disposition, ISSN: 00909556 1521009X

Harvey Wong; Vincent Tong; K. Wayne Riggs; Dan W. Rurak; Frank S. Abbott; Sanjeev Kumar

August 1, 2007

Cost-effectiveness analysis of trastuzumab in the adjuvant setting for treatment of HER2-positive breast cancer

Cancer, ISSN: 0008543X 10970142

Louis P. Garrison Jr.; Deborah Lubeck; Deepa Lalla; Virginia Paton; Amylou Dueck; Edith A. Perez

August 1, 2007

Epithelial-vascular cross talk mediated by VEGF-A and HGF signaling directs primary septae formation during distal lung morphogenesis

Developmental Biology, ISSN: 00121606

Hiroaki Yamamoto; Eun Jun Yun; Hans-Peter Gerber; Napoleone Ferrara; Jeffrey A. Whitsett; Thiennu H. Vu

August 1, 2007

Enhanced protein production by engineered zinc finger proteins

Biotechnology and Bioengineering, ISSN: 00063592 10970290

Andreas Reik; Yuanyue Zhou; Trevor N. Collingwood; Lyndon Warfe; Victor Bartsevich; Yanhong Kong; Karla A. Henning; Barrett K. Fallentine; Lei Zhang; Xiaohong Zhong; Yann Jouvenot; Andrew C. Jamieson; Edward J. Rebar; Casey C. Case; Alan Korman; Xiao-Yong Li; Amelia Black; David J. King; Philip D. Gregory

August 1, 2007

PDE4B5, a novel, super-short, brain-specific cAMP phosphodiesterase-4 variant whose isoform-specifying N-terminal region is identical to that of cAMP phosphodiesterase-4D6 (PDE4D6)

Journal of Pharmacology and Experimental Therapeutics, ISSN: 00223565 15210103

York-Fong Cheung; Zhengyan Kan; Philip Garrett-Engele; Irene Gall; Hannah Murdoch; George S. Baillie; Luiz Miguel Camargo; Jason M. Johnson; Miles D. Houslay; John C. Castle

August 1, 2007

EGFL7 regulates the collective migration of endothelial cells by restricting their spatial distribution

Development (Cambridge), ISSN: 09501991

Maike Schmidt; Kim Paes; Ann De Mazière; Tanya Smyczek; Stacey Yang; Gray; French; Ian Kasman; Judith Klumperman; Dennis S. Rice; Weilan Ye

August 1, 2007

Structural and functional analysis of the ligand specificity of the HtrA2/Omi PDZ domain

Protein Science, ISSN: 09618368 1469896X

Yingnan Zhang; Brent A. Appleton; Ping Wu; Wiesmann; Sachdev S. Sidhu

August 1, 2007

Think like a scientist - Behave like a business

BioPharm International, ISSN: 1542166X

Sue E. Steven

July 30, 2007

Cyclin E overexpression impairs progression through mitosis by inhibiting APCCdh1

Journal of Cell Biology, ISSN: 00219525 00219525

Jamie M. Keck; Matthew K. Summers; Donato Tedesco; Susanna Ekholm-Reed; Li-Chiou Chuang; Peter K Jackson; Steven I. Reed

July 25, 2007

Sequence and structure evolved separately in a ribosomal ubiquitin variant

EMBO Journal, ISSN: 02614189 14602075

André Catic; Zhen-Yu J. Sun; Daniel M. Ratner; Shahram Misaghi; Eric Spooner; John Samuelson; Gerhard Wagner; Hidde L. Ploegh

July 23, 2007

Falling into TRAPS - Receptor misfolding in the TNF receptor 1-associated periodic fever syndrome

Arthritis Research and Therapy, ISSN: 14786354 14786362

Fiona C. Kimberley; Adrian A. Lobito; Richard M. Siegel; Gavin R. Screaton

July 18, 2007

A material science perspective of pharmaceutical solids

International Journal of Pharmaceutics, ISSN: 03785173

Yong Cui

July 17, 2007

A novel exosite on coagulation factor VIIa and its molecular interactions with a new class of peptide inhibitors

Biochemistry, ISSN: 00062960

Roberge; Santell; Dennis; Eigenbrot; Dwyer; Lazarus

July 16, 2007

Human T-lymphotropic virus type-1 p30 alters cell cycle G2 regulation of T lymphocytes to enhance cell survival

Retrovirology, ISSN: 17424690

Antara Datta; Lee Silverman; Andrew J. Phipps; Hajime Hiraragi; Lee Ratner; Michael D. Lairmore

July 15, 2007

Antibody-drug conjugates targeted to CD79 for the treatment of non-Hodgkin lymphoma

Blood, ISSN: 00064971 00064971

Andrew G. Polson; Shang-Fan Yu; Kristi Elkins; Bing Zheng; Suzanna Clark; Gladys S. Ingle; Dionysos S. Slaga; Lynne Giere; Du; Christine Tan; Hongo; Alvin Gogineni; Mary J. Cole; Richard L. Vandlen; Jean-Philippe Stephan; Judy Young; Wesley S. Chang; Suzie J. Scales; Ross; Dan L. Eaton; Allen Ebens

July 13, 2007

A ubiquitin-binding motif in the translesion DNA polymerase Rev1 mediates its essential functional interaction with ubiquitinated proliferating cell nuclear antigen in response to DNA damage

Journal of Biological Chemistry, ISSN: 00219258 1083351X

Adam Wood; Parie Garg; Peter M. J. Burgers

July 13, 2007

Response: Does Bid Play a Role in the DNA Damage Response?

Cell, ISSN: 00928674

Kaufmann; Lin Tai; Paul G. Ekert; David C.S. Huang; Fiona Norris; Ralph K. Lindemann; Ricky W. Johnstone; Vishva M. Dixit; Damien Arnoult; Andreas Strasser

July 9, 2007

Tissue factor: A mediator of inflammatory cell recruitment, tissue injury, and thrombus formation in experimental colitis

Journal of Experimental Medicine, ISSN: 00221007 00221007

Christoph Anthoni; Janice Russell; Katherine C. Wood; Karen Y. Stokes; Thorsten Vowinkel; Daniel Kirchhofer; D. Neil Granger

July 5, 2007

Bioprocess membrane technology

Journal of Membrane Science, ISSN: 03767388

Robert Van Reis; Andrew Zydney

July 4, 2007

The Nogo-66 receptor NgR1 is required only for the acute growth cone-collapsing but not the chronic growth-inhibitory actions of myelin inhibitors

Journal of Neuroscience, ISSN: 02706474 02706474

Onanong Chivatakarn; Shinjiro Kaneko; Zhigang He; Marc Tessier-Lavigne; Roman J. Giger

July 3, 2007

Bcl-2 is the target of a UV-inducible apoptosis switch and a node for UV signaling

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Dejan Knezevic; Wengeng Zhang; Patrick J. Rochette; Douglas E. Brash

July 1, 2007

GeneHub-GEPIS: Digital expression profiling for normal and cancer tissues based on an integrated gene database

Nucleic Acids Research, ISSN: 03051048 13624962

Yan Zhang; Shiuh-Ming Luoh; Lawrence S. Hon; Robert Baertsch; William I. Wood; Zemin Zhang

July 1, 2007

Response [2]

Journal of Magnetic Resonance Imaging, ISSN: 10531807 15222586

Joan M. Greve; Simon P. Williams

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