Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 9801 - 9850 OF 15217 RESULTS

The biology and therapeutic potential of interleukin 27
Journal of Molecular Medicine, ISSN: 09462716
Marcel Batten; Nico Ghilardi
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A phase I/II randomized open-label multicenter trial of efalizumab, a humanized anti-CD11a, anti-LFA-1 in renal transplantation
American Journal of Transplantation, ISSN: 16006135 16006143
Vincenti; Mendez; Pescovitz; Rajagopalan; Wilkinson; Butt; Laskow; Slakey; Lorber; Jay Garg; Marvin Garovoy
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CanPredict: A computational tool for predicting cancer-associated missense mutations
Nucleic Acids Research, ISSN: 03051048 13624962
Joshua S. Kaminker; Yan Zhang; Colin K. Watanabe; Zemin Zhang
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Identification of a novel glutathione conjugate of flutamide in incubations with human liver microsomes
Drug Metabolism and Disposition, ISSN: 00909556 1521009X
Ping Kang; Deepak Dalvie; Evan Smith; Sue Zhou; Alan Deese
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Metabolism, pharmacokinetics, and excretion of a nonpeptidic substance P receptor antagonist, ezlopitant, in normal healthy male volunteers: Characterization of polar metabolites by chemical derivatization with dansyl chloride
Drug Metabolism and Disposition, ISSN: 00909556 1521009X
Chandra Prakash; John O'Donnell; S. Cyrus Khojasteh
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Growth factors gene expression in the developing lung
Acta Paediatrica, International Journal of Paediatrics, ISSN: 08035253 16512227
Edward M. Mager; Gabriele Renzetti; Alexander Auais; Giovanni Piedimonte
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GA-binding protein is dispensable for neuromuscular synapse formation and synapse-specific gene expression
Molecular and Cellular Biology, ISSN: 02707306
Alexander Jaworski; Cynthia L. Smith; Steven J. Burden
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The Biflow: An instrument for transfer-loop mediated, continuous, preparative-scale isoelectric trapping separations
Electrophoresis, ISSN: 01730835 15222683
Evan Shave; Gyula Vigh
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UNC5C is required for spinal accessory motor neuron development
Molecular and Cellular Neuroscience, ISSN: 10447431
Dillon; Jevince; Hinck; Ackerman; Lu; Marc Tessier-Lavigne; Kaprielian
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Characterization of the rat urokinase plasminogen activator receptor promoter in PC12 cells
Journal of Neuroscience Research, ISSN: 03604012 10974547
Feng Su; Kathy R. Kozak; Harvey Herschman; Srinivasa T. Reddy; Robin Farias-Eisner
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Multiplex assay for comprehensive genotyping of genes involved in drug metabolism, excretion, and transport
Clinical Chemistry, ISSN: 00099147
Thomas M. Daly; Carmen M. Dumaual; Xin Miao; Mark W. Farmen; Reuben K. Njau; Dong-Jing Fu; Nancy L. Bauer; Sandra Close; Nancy Watanabe; Carsten Bruckner; Paul Hardenbol; Richard D. Hockett
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Secreted sulfatases Sulf1 and Sulf2 have overlapping yet essential roles in mouse neonatal survival
PLoS ONE, ISSN: 19326203
Charles R. Holst; Hani Bou-Reslan; Bryan B. Gore; Karen Wong; Deanna Grant; Sreedevi Chalasani; Richard A. D. Carano; Gretchen D. Frantz; Marc Tessier-Lavigne; Brad Bolon; French; Avi Ashkenazi
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Epigenome scans and cancer genome sequencing converge on WNK2, a kinase-independent suppressor of cell growth
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Chibo Hong; K. Scott Moorefield; Peter Jun; Kenneth D. Aldape; Samir Kharbanda; Phillips; Joseph F. Costello
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2007 highlights of advance in the pharmaceutical sciences: An American Association of Pharmaceutical Scientists (AAPS) perspective
AAPS Journal, ISSN: 15507416
Marilyn N. Martinez; Peter Bonate; Robert L. Chapman; Anne De Groot; Susan D'Souza; Naushad Ghilazi; Vivian Gray; Vishal K. Gupta; Kim Huynh-Ba; Sunil Iyer; Arya Jayatilaka; Amita Joshi; H. Thomas Karnes; Mansoor Khan; Patrick Liu; Craig Lunte; Christopher R. McCurdy; Marilyn E. Morris; Kenneth J. Norris; Phillip Ramsey; Sanjay Sehgal; Manuel Zahn
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Inhibition of VEGF-A prevents the angiogenic switch and results in increased survival of Apc+/min mice
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Nina Korsisaari; Ian Kasman; William F. Forrest; Navneet Pal; Wei Bai; Fuh; Franklin V. Peale Jr.; Ron Smits; Napoleone Ferrara
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Erratum: Armed antibodies targeting the mucin repeats of the ovarian cancer antigen, MUC16, are highly efficacious in animal tumor models (Cancer Research (2007) 67, (4924-4932))
Cancer Research, ISSN: 00085472
Youjun Chen; Suzanna Clark; Wong; Yongmei Chen; Chen; Dennis; Luis; Fiona Zhong; Sheila Bheddah; Koeppen; Alvin Gogineni; Paul G. Polakis; William Mallet
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A Core Complex of BBS Proteins Cooperates with the GTPase Rab8 to Promote Ciliary Membrane Biogenesis
Cell, ISSN: 00928674
Maxence V. Nachury; Alexander V. Loktev; Qihong Zhang; Christopher J. Westlake; Johan Peränen; Andreas Merdes; Diane C. Slusarski; Richard H. Scheller; J.Fernando Bazan; Val C. Sheffield; Peter K Jackson
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A novel inhibitor of the alternative pathway of complement reverses inflammation and bone destruction in experimental arthritis
Journal of Experimental Medicine, ISSN: 00221007 00221007
Kenneth J. Katschke Jr.; Karim Y. Helmy; Micah Steffek; Hongkang Xi; Jianping Yin; Wyne P. Lee; Gribling; Kai H. Barck; Richard A. D. Carano; Taylor; Linda Rangell; Laurie Diehl; Hass; Wiesmann; Menno Van Lookeren Campagne
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Safety outcomes of Alteplase among acute ischemic stroke patients with special characteristics
Neurocritical Care, ISSN: 15416933
Sylaja; Wei Dong; James C. Grotta; Mary K. Miller; Kristen Tomita; Scott Hamilton; Charles P. Semba; Michael D. Hill
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Identifying specificity profiles for peptide recognition modules from phage-displayed peptide libraries
Nature Protocols, ISSN: 17542189 17502799
Raffi Tonikian; Yingnan Zhang; Charles Boone; Sachdev S. Sidhu
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Association of control and risk of severe asthma-related events in severe or difficult-to-treat asthma patients
Allergy: European Journal of Allergy and Clinical Immunology, ISSN: 01054538 13989995
Sean D. Sullivan; Sally E. Wenzel; Bresnahan; Zheng; June H. Lee; Pritchard; Tripthi V. Kamath; Weiss
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Nerve growth factor mediates steroid-resistant inflammation in respiratory syncytial virus infection
Pediatric Pulmonology, ISSN: 87556863 10990496
Lida Mohtasham; Alexander Auais; Giovanni Piedimonte
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A pilot study of tumor necrosis factor inhibition in erosive/inflammatory osteoarthritis of the hands
Journal of Rheumatology, ISSN: 0315162X
Molly D. Magnano; Eliza F. Chakravarty; Corrie Broudy; Lorinda Chung; Ariella Kelman; Jennifer Hillygus; Mark C. Genovese
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Do deaf and hard of hearing youth need antitobacco education?
American Annals of the Deaf, ISSN: 0002726X
Barbara A. Herman; Leanne Streja; Coen A. Bernaards; Elizabeth A. Eckhardt; Heidi B. Kleiger; Lauren Maucere; Glenn Wong; Shari Barkin; Roshan Bastani
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Presence of methicillin resistant Staphylococcus aureus in respiratory cultures from cystic fibrosis patients is associated with lower lung function
Pediatric Pulmonology, ISSN: 87556863 10990496
Clement L. Ren; Morgan; Michael W. Konstan; Michael S. Schechter; Wagener; Kathryn A. Fisher; Warren E. Regelmann
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Exploring and designing protein function with restricted diversity
Current Opinion in Chemical Biology, ISSN: 13675931
Sachdev S. Sidhu; Anthony A. Kossiakoff
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Dendritic cell vaccine hits FDA roadblock.
Managed Care, ISSN: 10623388
Thomas Morrow
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Real-world Evaluation of Asthma Control and Treatment (REACT): Findings from a national Web-based survey
Journal of Allergy and Clinical Immunology, ISSN: 00916749
Stephen P. Peters; Craig A. Jones; Tmirah Haselkorn; David R. Mink; David J. Valacer; Weiss
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The soluble Wnt receptor Frizzled8CRD-hFc inhibits the growth of teratocarcinomas in vivo
Cancer Research, ISSN: 00085472
Venita I. DeAlmeida; Li Miao; James A. Ernst; Koeppen; Paul G. Polakis; Bonnee Rubinfeld
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Characterization of protein-protein interactions critical for poliovirus replication: Analysis of 3AB and VPg binding to the RNA-dependent RNA polymerase
Journal of Virology, ISSN: 0022538X
Daniel M. Strauss; Deborah S. Wuttke
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Transitioning patients from efalizumab to alternative psoriasis therapies: Findings from an open-label, multicenter, Phase IIIb study
International Journal of Dermatology, ISSN: 00119059 13654632
Alan Menter; Tiffani K. Hamilton; Darryl P. Toth; Hoi M. Leung; Graham Wetherill; Brian Hennessey; Marvin Garovoy; Paul Kwon; David M. Pariser
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Structure of the catalytic domain of human polo-like kinase 1
Biochemistry, ISSN: 00062960
Michael Kothe; Darcy Kohls; Simon Low; Rocco Coli; Alan C. Cheng; Suzanne L. Jacques; Theresa L. Johnson; Lewis; Christine Loh; Jim Nonomiya; Alissa L. Sheils; Kimberly A. Verdries; Thomas A. Wynn; Cyrille Kuhn; Yuan-Hua Ding
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Armed antibodies targeting the mucin repeats of the ovarian cancer antigen, MUC16, are highly efficacious in animal tumor models
Cancer Research, ISSN: 00085472
Youjun Chen; Suzanna Clark; Wong; Yongmei Chen; Chen; Dennis; Luis; Fiona Zhong; Sheila Bheddah; Koeppen; Alvin Gogineni; Paul G. Polakis; William Mallet
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Targeting VEGF-A to treat cancer and age-related macular degeneration
Annual Review of Medicine, ISSN: 00664219
Napoleone Ferrara; Robert Mass; Claudio Campa; Robert Kim
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Krüppel-like transcription factor 13 regulates T lymphocyte survival in vivo
Journal of Immunology, ISSN: 00221767
Meixia Zhou; Lisa McPherson; Dongdong Feng; An Song; Chen Dong; Shu-Chen Lye; Lu Zhou; Xiaoyan Shi; Yong-Tae Ahn; Demin Wang; Carol Clayberger; Alan M. Krensky
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Loop anchor modification causes the population of an alternative native state in an SH3-like domain
Protein Science, ISSN: 09618368 1469896X
Jane A. Knappenberger; Juliette T.J. Lecomte
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Targeted and untargeted CD137L fusion proteins for the immunotherapy of experimental solid tumors
Clinical Cancer Research, ISSN: 10780432
Nan Zhang; Rebecca E. Sadun; Robyn S. Arias; Meg L. Flanagan; Suzanne M. Sachsman; Yu-Chih Nien; Leslie A. Khawli; Peisheng Hu; Alan L. Epstein
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Quantitative translational pharmacology for monoclonal antibody dose and dose-schedule determination
American Pharmaceutical Review, ISSN: 10998012
Nelson L'ntshotsholé Jumbe
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Monoclonal antibody now available to prevent red blood cell breakdown.
Managed Care, ISSN: 10623388
Thomas Morrow
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Selective clearance of glycoforms of a complex glycoprotein pharmaceutical caused by terminal N-acetylglucosamine is similar in humans and cynomolgus monkeys
Glycobiology, ISSN: 09596658 14602423
Andrew J.S. Jones; Damon I. Papac; Chin; Rodney Keck; Sharon A. Baughman; Yvonne S. Lin; Johannes Kneer; John E. Battersby
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Demographic and clinical characteristics of children and adolescents with severe or difficult-to-treat asthma
Journal of Allergy and Clinical Immunology, ISSN: 00916749
Bradley E. Chipps; Stanley J. Szefler; F. Estelle R. Simons; Tmirah Haselkorn; David R. Mink; Yamo Deniz; June H. Lee
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Full-length antibodies on display
Nature Biotechnology, ISSN: 10870156 15461696
Sachdev S. Sidhu
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Quantifying the treatment effect explained by markers in the presence of measurement error
Statistics in Medicine, ISSN: 02776715 10970258
Somnath Sarkar; Yongming Qu
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Role for Msh5 in the regulation of Ig class switch recombination
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Hideharu Sekine; Ricardo C. Ferreira; Qiang Pan-Hammarström; Robert R. Graham; Beth Ziemba; Sandra S. De Vries; Jiabin Liu; Keli Hippen; Thearith Koeuth; Ward Ortmann; Akiko Iwahori; Margaret K. Elliott; Steven Offer; Cara Skon; Likun Du; Jill Novitzke; Annette T. Lee; Nianxi Zhao; Joshua D. Tompkins; David Altshuler; Peter K. Gregersen; Charlotte Cunningham-Rundles; Reuben S. Harris; Chengtao Her; David L. Nelson; Lennart Hammarström; Gary S. Gilkeson; Timothy W. Behrens
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Spectroscopic evaluation of the stabilization of humanized monoclonal antibodies in amino acid formulations
International Journal of Pharmaceutics, ISSN: 03785173
Fei Tian; C. Russell Middaugh; Tom Offerdahl; Eric Munson; Samir Sane; J. Howard Rytting
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The BH3-Only Protein Bid Is Dispensable for DNA Damage- and Replicative Stress-Induced Apoptosis or Cell-Cycle Arrest
Cell, ISSN: 00928674
Kaufmann; Lin Tai; Paul G. Ekert; David C.S. Huang; Fiona Norris; Ralph K. Lindemann; Ricky W. Johnstone; Vishva M. Dixit; Andreas Strasser
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ElaD, a deubiquitinating protease expressed by E. coli
PLoS ONE, ISSN: 19326203
André Catic; Shahram Misaghi; Gregory A. Korbel; Hidde L. Ploegh
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Netrin-1/DCC signaling in commissural axon guidance requires cell-autonomous expression of heparan sulfate
Journal of Neuroscience, ISSN: 02706474 02706474
Yoshihiro Matsumoto; Fumitoshi Irie; Masaru Inatani; Marc Tessier-Lavigne; Yu Yamaguchi
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Ala657 and conserved active site residues promote fibroblast activation protein endopeptidase activity via distinct mechanisms of transition state stabilization
Biochemistry, ISSN: 00062960
Sarah A. Meadows; Conrad Yap Edosada; Mark Mayeda; Thuy Tran; Quan; Helga Raab; Wiesmann; Beni B. Wolf
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Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Robert R. Graham; Chieko Kyogoku; Snaevar Sigurdsson; Irina A. Vlasova; Leela R. L. Davies; Emily C. Baechler; Robert M. Plenge; Thearith Koeuth; Ward Ortmann; Geoffrey Hom; Jason W. Bauer; Clarence Gillett; Noel Burtt; Deborah S. Cunninghame Graham; Robert Onofrio; Michelle Petri; Iva Gunnarsson; Elisabet Svenungsson; Lars Rönnblom; Gunnel Nordmark; Peter K. Gregersen; Kathy L. Moser; Patrick M. Gaffney; Lindsey A. Criswell; Timothy J. Vyse; Ann-Christine Syvänen; Paul R. Bohjanen; Mark J. Daly; Timothy W. Behrens; David Altshuler
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