Genentech: Publications

January 1, 2008

The safety of bone allografts used in dentistry: A review

Journal of the American Dental Association, ISSN: 00028177

Dan Holtzclaw; Nicholas Toscano; Lisa Eisenlohr; Don Callan

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January 1, 2008

The complex inter-relationships between protein flexibility and stability

Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549

Tim J. Kamerzell; C. Russell Middaugh

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January 1, 2008

Anti-CD22-MCC-DM1 and MC-MMAF conjugates: Impact of assay format on pharmacokinetic parameters determination

Bioconjugate Chemistry, ISSN: 10431802

Jean-Philippe Stephan; Pamela Chan; Chien C. Lee; Nelson; J. Michael Elliott; Charity Bechtel; Helga Raab; David Xie; Jon Akutagawa; Jakub Baudys; Ola M. Saad; Saileta Prabhu; Wai Lee T. Wong; Richard L. Vandlen; Fred Jacobson; Allen Ebens

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January 1, 2008

15 Capillary electrophoresis and bioanalysis

Separation Science and Technology, ISSN: 01496395

Oscar Salas-Solano; Chantal Felten

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January 1, 2008

The Notch pathway in prostate development and cancer

Differentiation, ISSN: 14320436 03014681

Kevin G. Leong; Gao

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January 1, 2008

Evaluation of hydrate-screening methods

Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549

Yonc Cui; Erica Yao

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January 1, 2008

Synthesis of a cross-bridged cyclam derivative for peptide conjugation and 64Cu radiolabeling

Bioconjugate Chemistry, ISSN: 10431802

C. Andrew Boswell; Celeste A. S. Regino; Kwamena E. Baidoo; Karen J. Wong; Ambika Bumb; Heng Xu; Diane E. Milenic; James A. Kelley; Christopher C. Lai; Martin W. Brechbiel

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January 1, 2008

Stopping replication, at the beginning

Nature Chemical Biology, ISSN: 15524469 15524450

Peter K Jackson

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January 1, 2008

Summary statement novel agents in the treatment of lung cancer: Fifth Cambridge conference assessing opportunities for combination therapy

Journal of Thoracic Oncology, ISSN: 15561380 15560864

Thomas J. Lynch; George R. Blumenschein; Jeff A. Engelman; Igor Espinoza-Delgado; Ramaswamy Govindan; Jeffrey H. Hanke; Nasser H. Hanna; John V. Heymach; Fred R. Hirsch; Pasi A. Jänne; Rogerio C. Lilenbaum; Ronald B. Natale; Gregory J. Riely; Lecia V. Sequist; Geoffrey I. Shapiro; Alice T. Shaw; Frances A. Shepherd; Mark A. Socinski; A Gregory Sorensen; Heather A. Wakelee; Aaron Weitzman

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January 1, 2008

Prediction of the possibility of the second peak of drug plasma concentration time curve after iv bolus administration from the standpoint of the traditional multi-compartmental linear pharmacokinetics

Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549

Leonid M. Berezhkovskiy

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January 1, 2008

Ten-year outcomes following traumatic brain injury: A population-based cohort

Brain Injury, ISSN: 1362301X 02699052

Cameron; David M. Purdie; Kliewer; Rod J. McClure

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January 1, 2008

Ranibizumab Combined With Verteporfin Photodynamic Therapy in Neovascular Age-related Macular Degeneration (FOCUS): Year 2 Results

American Journal of Ophthalmology, ISSN: 00029394

Andrew N. Antoszyk; Lisa Tuomi; Carol Chung; Angele Singh

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January 1, 2008

Blockade of CD11a by efalizumab in psoriasis patients induces a unique state of T-cell hyporesponsiveness

Journal of Investigative Dermatology, ISSN: 15231747 0022202X

Emma Guttman-Yassky; Yulia Vugmeyster; Michelle A. Lowes; Francesca Chamian; Toyoko Kikuchi; Mark Kagen; Patricia Gilleaudeau; Edmund Lee; Brisdell Hunte; Howell; Wolfgang Dummer; Bodary; James G. Krueger

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January 1, 2008

A key claudin extracellular loop domain is critical for epithelial barrier integrity

American Journal of Pathology, ISSN: 00029440

Mrsny; G. Thomas Brown; Kirsten Gerner-Smidt; Andre G. Buret; Jon B. Meddings; Quan; Michael Koval; Asma Nusrat

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January 1, 2008

Ranibizumab for macular edema due to retinal vein occlusions: Implication of VEGF as a critical stimulator

Molecular Therapy, ISSN: 15250024 15250016

Peter A. Campochiaro; Gulnar Hafiz; Syed Mahmood Shah; Quan Dong Nguyen; Howard Ying; Diana V. Do; Edward Quinlan; Ingrid Zimmer-Galler; Julia A. Haller; Sharon D. Solomon; Jennifer U. Sung; Yasmin Hadi; Kashif A. Janjua; Nida Jawed; David F. Choy; Joseph R. Arron

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January 1, 2008

Insurance status and asthma-related health care utilization in patients with severe asthma

Annals of Allergy, Asthma and Immunology, ISSN: 10811206

Anju T. Peters; Julie C. Klemens; Tmirah Haselkorn; Weiss; Leslie C. Grammer; June H. Lee; Hubert Chen

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January 1, 2008

Assessing productivity loss and activity impairment in severe or difficult-to-treat asthma

Value in Health, ISSN: 15244733 10983015

Hubert Chen; Paul D. Blanc; Mary Lou Hayden; Eugene R. Bleecker; Chawla; June H. Lee

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January 1, 2008

Compliance and persistence in pediatric and adult patients receiving growth hormone therapy

Endocrine Practice, ISSN: 1530891X

Rosenfeld; Bert Bakker

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January 1, 2008

Recently-approved sapropterin reduces phenylalanine levels

Managed Care, ISSN: 10623388

Thomas Morrow

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January 1, 2008

T-cell lymphomas in T-cell-specific Pten-deficient mice originate in the thymus

Leukemia, ISSN: 14765551 08876924

Thijs Hagenbeek; Hergen Spits

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January 1, 2008

Long-term safety of recombinant human growth hormone in Turner syndrome

Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X 0021972X

Katrina Bolar; Andrew R. Hoffman; Thomas J. Maneatis; Barbara M. Lippe

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January 1, 2008

Height velocity targets from the national cooperative growth study for first-year growth hormone responses in short children

Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X 0021972X

Bert Bakker; James W. Frane; Henry Anhalt; Barbara M. Lippe; Rosenfeld

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January 1, 2008

Personalized medicine complicates medical decision-making

Managed Care, ISSN: 10623388

Thomas Morrow

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January 1, 2008

Randomized, Double-Masked, Sham-Controlled Trial of Ranibizumab for Neovascular Age-related Macular Degeneration: PIER Study Year 1

American Journal of Ophthalmology, ISSN: 00029394

Carl D. Regillo; David M. Brown; Prema Abraham; Huibin Yue; Tsontcho Ianchulev; Susan Schneider; Naveed Shams

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January 1, 2008

Comparison of two approaches for handling missing covariates in logistic regression

Educational and Psychological Measurement, ISSN: 15523888 00131644

Chao-Ying Joanne Peng; Jin Zhu

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January 1, 2008

The business case for energy management in high-tech industries

Energy Efficiency, ISSN: 1570646X 15706478

Evan Mills; Gary Shamshoian; Michele Blazek; Phil Naughton; Robert S. Seese; William Tschudi; Dale Sartor

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January 1, 2008

The proteasome inhibitor bortezomib in combination with gemcitabine and carboplatin in advanced non-small cell lung cancer: A California Cancer Consortium phase I study

Journal of Thoracic Oncology, ISSN: 15561380 15560864

Angela M. Davies; Christopher Ruel; Primo N. Lara; Derick H. Lau; Paul H. Gumerlock; Richard Bold; Stephen Shibata; Heinz-Josef Lenz; David P. Schenkein; David R. Gandara

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January 1, 2008

Optimization approaches in the routine analysis of monoclonal antibodies by capillary electrophoresis

LC-GC Europe, ISSN: 14716577

Oscar Salas-Solano; Lynn Gennaro; Chantal Felten

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January 1, 2008

Coordination of growth rate, cell cycle, stress response, and metabolic activity in yeast

Molecular Biology of the Cell, ISSN: 10591524

Matthew J. Brauer; Curtis Huttenhower; Edoardo M. Airoldi; Rachel Rosenstein; John C. Matese; David Gresham; Viktor M. Boer; Olga G. Troyanskaya; David Botstein

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January 1, 2008

Ongoing sonic hedgehog signaling is required for dorsal midline formation in the developing forebrain

Developmental Neurobiology, ISSN: 19328451 1932846X

Monica Hayhurst; Bryan B. Gore; Marc Tessier-Lavigne; Susan K. McConnell

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January 1, 2008

In vivo imaging of mucosal CD4+ T cells using single photon emission computed tomography in a murine model of colitis

Journal of Immunological Methods, ISSN: 00221759

Bittoo Kanwar; Dong Wei Gao; Andrew B. Hwang; James P. Grenert; Simon P. Williams; Benjamin Franc; Joseph M. McCune

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January 1, 2008

Genome wide screens in yeast to identify potential binding sites and target genes of DNA-binding proteins

Nucleic Acids Research, ISSN: 03051048 13624962

Jue Zeng; Jizhou Yan; Ting Wang; Deborah Mosbrook-Davis; Kyle T. Dolan; Ryan Christensen; Gary D. Stormo; David Haussler; Richard H. Lathrop; Rainer Brachmann; Shawn M. Burgess

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January 1, 2008

Polymorphism at the TNF superfamily gene TNFSF4 confers susceptibility to systemic lupus erythematosus

Nature Genetics, ISSN: 10614036 15461718

Deborah S. Cunninghame Graham; Robert R. Graham; Harinder Manku; Andrew K. Wong; John C. Whittaker; Patrick M. Gaffney; Kathy L. Moser; John D. Rioux; David Altshuler; Timothy W. Behrens; Timothy J. Vyse

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January 1, 2008

Computational approaches for predicting causal missense mutations in cancer genome projects

Current Bioinformatics, ISSN: 15748936

Lawrence S. Hon; Joshua S. Kaminker; Zemin Zhang

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January 1, 2008

High CD21 expression inhibits internalization of anti-CD19 antibodies and cytotoxicity of an anti-CD19-drug conjugate

British Journal of Haematology, ISSN: 00071048 13652141

Gladys S. Ingle; Pamela Chan; J. Michael Elliott; Wesley S. Chang; Koeppen; Jean-Philippe Stephan; Suzie J. Scales

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January 1, 2008

Recommended changes to oncology clinical trial design: Revolution or evolution?

European Journal of Cancer, ISSN: 09598049

Ratain; Rachel W. Humphrey; Gary Gordon; Gwendolyn Fyfe; Peter C. Adamson; Thomas R. Fleming; Walter M. Stadler; Donald A. Berry; Carl C. Peck

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January 1, 2008

Blocking vascular endothelial growth factor-A inhibits the growth of pituitary adenomas and lowers serum prolactin level in a mouse model of multiple endocrine neoplasia type 1

Clinical Cancer Research, ISSN: 10780432

Nina Korsisaari; Ross; Xiumin Wu; Marcin Kowanetz; Navneet Pal; Linda Hall; Jeffrey Eastham-Anderson; William F. Forrest; Nicholas Van Bruggen; Franklin V. Peale Jr.; Napoleone Ferrara

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January 1, 2008

Characterization of a complex glycoprotein whose variable metabolic clearance in humans is dependent on terminal N-acetylglucosamine content

Biologicals, ISSN: 10451056 10958320

Rodney Keck; Namita Nayak; Laura Lerner; Shanta Raju; Stacey Ma; Thomas Schreitmueller; Steven M. Chamow; Kathy Moorhouse; Claire Kotts; Andrew J.S. Jones

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January 1, 2008

Subspecialty differences in asthma characteristics and management

Mayo Clinic Proceedings, ISSN: 00256196

Hubert Chen; Charles A. Johnson; Tmirah Haselkorn; June H. Lee; Elliot Israel

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January 1, 2008

hADA2a and hADA3 are required for acetylation, transcriptional activity and proliferative effects of β-catenin

Cancer Biology and Therapy, ISSN: 15384047 15558576

Min Yang; Marian L. Waterman; Rainer Brachmann

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January 1, 2008

In reply

Annals of Emergency Medicine, ISSN: 01960644

Andrew R. Erdman

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January 1, 2008

The effects of CYP3A4 inhibition on erlotinib pharmacokinetics: Computer-based simulation (SimCYP™) predicts in vivo metabolic inhibition

European Journal of Clinical Pharmacology, ISSN: 00316970

Ashok Rakhit; Michael P. Pantze; Scott Fettner; Hannah M. Jones; Jean-Eric Charoin; Myriam Riek; Bert L. Lum; Marta Hamilton

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January 1, 2008

Improved health-related quality of life for patients with active rheumatoid arthritis receiving rituximab - Results of the dose-ranging assessment: International clinical evaluation of rituximab in rheumatoid arthritis (DANCER) trial

Journal of Rheumatology, ISSN: 0315162X

Philip J. Mease; Dennis A. Revicki; Jacek Szechinski; Maria Greenwald; Alan Kivitz; Leonor Barile-Fabris; Jatinderpal Kalsi; Jennifer Eames; Marjatta Leirisalo-Repo

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January 1, 2008

Quantification of viable tumor microvascular characteristics by multispectral analysis

Magnetic Resonance in Medicine, ISSN: 15222594 07403194

Berry; Kai H. Barck; MaryAnn Go; Ross; Xiumin Wu; Simon P. Williams; Alvin Gogineni; Mary J. Cole; Nicholas Van Bruggen; Fuh; Franklin V. Peale Jr.; Napoleone Ferrara; Ross; Ralph H. Schwall; Richard A. D. Carano

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January 1, 2008

Accounting for Interim Analyses in the Assessment of Program Expected Net Present Value

Therapeutic Innovation and Regulatory Science, ISSN: 21684790

Lee D. Kaiser; Jeffrey D. Helterbrand; Hal V. Barron

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January 1, 2008

Ranibizumab Combined With Verteporfin Photodynamic Therapy in Neovascular Age-related Macular Degeneration (FOCUS): Year 2 Results

American Journal of Ophthalmology, ISSN: 00029394

Andrew N. Antoszyk; Lisa Tuomi; Carol Y. Chung; Angele Singh

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December 26, 2007