Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 9851 - 9900 OF 15217 RESULTS

Assays for the Release of Viral Vector Gene Therapy Products for Human Clinical Trials
Concepts in Genetic Medicine,
Flavia Borellini
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The tumour-suppressor Scribble dictates cell polarity during directed epithelial migration: Regulation of Rho GTPase recruitment to the leading edge
Oncogene, ISSN: 09509232 14765594
Dow; Kauffman; Caddy; Andrew S. Peterson; Jane; Russell; Humbert
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Glycosylphosphatidylinositol-Anchored High-Density Lipoprotein-Binding Protein 1 Plays a Critical Role in the Lipolytic Processing of Chylomicrons
Cell Metabolism, ISSN: 15504131
Anne P. Beigneux; Brandon S.J. Davies; Peter Gin; Michael M. Weinstein; Emily Farber; Xin Qiao; Franklin V. Peale Jr.; Bunting; Rosemary L. Walzem; Jinny S. Wong; William S. Blaner; Zhi-Ming Ding; Kristan Melford; Nuttaporn Wongsiriroj; Xiao Shu; Frederic J. De Sauvage; Robert O. Ryan; Loren G. Fong; André Bensadoun; Stephen G. Young
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Plexin-B2 controls the development of cerebellar granule cells
Journal of Neuroscience, ISSN: 02706474 02706474
Roland H. Friedel; Géraldine Kerjan; Helen Rayburn; Ulrich Schüller; Constantino Sotelo; Marc Tessier-Lavigne; Alain Chedotal
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Swapping the gene-specific and regional silencing specificities of the Hst1 and Sir2 histone deacetylases
Molecular and Cellular Biology, ISSN: 02707306
Janet Mead; Ron McCord; Laura Youngster; Mandakini Sharma; Marc R. Gartenberg; Andrew K. Vershon
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Vasorelaxation induced by vascular endothelial growth factor in the human internal mammary artery and radial artery
Vascular Pharmacology, ISSN: 15371891
Wei Wei; Zhi-Wu Chen; Qin Yang; Hongkui Jin; Anthony Furnary; Xiao-Qiang Yao; Anthony P. C. Yim; Guo-Wei He
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Vascular targeting via caveolae
Nature Biotechnology, ISSN: 10870156 15461696
Kristy Red-Horse; Napoleone Ferrara
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Basic helix-loop-helix transcription factor heterocomplex of Yas1p and Yas2p regulates cytochrome P450 expression in response to alkanes in the yeast Yarrowia lipolytica
Eukaryotic Cell, ISSN: 15359778
Setsu Endoh-Yamagami; Kiyoshi Hirakawa; Daisuke Morioka; Ryouichi Fukuda; Akinori Ohta
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High-throughput automated system for crystallizing membrane proteins in lipidic mesophases
IEEE Transactions on Automation Science and Engineering, ISSN: 15455955
Avinash Peddi; Lalitha Muthusubramaniam; Yuan F. Zheng; Vadim Cherezov; Yohann Misquitta; Martin Caffrey
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Dimethylfumarate induces immunosuppression via glutathione depletion and subsequent induction of heme oxygenase 1
Journal of Investigative Dermatology, ISSN: 0022202X 15231747
Joachim C.U. Lehmann; Joanna J. Listopad; Christine U. Rentzsch; Frederik H. Igney; Arne Von Bonin; Hartwig H. Hennekes; Khusru Asadullah; Wolf-Dietrich F. Docke
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The 620W allele is the PTPN22 genetic variant conferring susceptibility to RA in a Dutch population
Rheumatology, ISSN: 14620324 14620332
Wesoly; Hu; Thabet; Chang; Uh; Allaart; Toes; Houwing-Duistermaat; Begovich; Tom W. J. Huizinga
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Regulation of myeloid progenitor cell proliferation/survival by IL-31 receptor and IL-31
Experimental Hematology, ISSN: 0301472X
Hal E. Broxmeyer; Ji Li; Giao Hangoc; Scott Cooper; Wen Tao; Charlie Mantel; Barbara Graham-Evans; Nico Ghilardi; Frederic J. De Sauvage
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ASC, Ipaf and Cryopyrin/Nalp3: bona fide intracellular adapters of the caspase-1 inflammasome
Microbes and Infection, ISSN: 12864579 1769714X
Sanjeev Mariathasan
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Design space for biotech products
BioPharm International, ISSN: 1542166X
Anurag S. Rathore; Ron Branning; Doug Cecchini
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Phosphorylation of a Wiscott-Aldrich syndrome protein-associated signal complex is critical in osteoclast bone resorption
Journal of Biological Chemistry, ISSN: 00219258 1083351X
Meenakshi A. Chellaiah; Dhandapani Kuppuswamy; Larry Lasky; Stefan Linder
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Species-dependent serum interference in a sandwich ELISA for Apo2L/TRAIL
Journal of Immunological Methods, ISSN: 00221759
Laura DeForge; Danny Shih; Derek Kennedy; Klara Totpal; Anan Chuntharapai; Bennett; Jason H. Drummond; Patricia Siguenza; Wai Lee T. Wong
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Robo1 and Robo2 cooperate to control the guidance of major axonal tracts in the mammalian forebrain
Journal of Neuroscience, ISSN: 02706474 02706474
Guillermina López-Bendito; Nuria Flames; Le Ma; Coralie Fouquet; Thomas Di Meglio; Alain Chedotal; Marc Tessier-Lavigne; Oscar Marín
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Utilizing the activation mechanism of serine proteases to engineer hepatocyte growth factor into a Met antagonist
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Daniel Kirchhofer; Michael T. Lipari; Santell; Karen L Billeci; Henry R. Maun; Wendy N. Sandoval; Paul Moran; John B.B. Ridgway; Eigenbrot; Lazarus
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Substrate tolerance of module 6 of the epothilone synthetase
Biochemistry, ISSN: 00062960
Martha Lovato Tse; R. Edward Watts; Chaitan Khosla
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IL-31-IL-31R interactions negatively regulate type 2 inflammation in the lung
Journal of Experimental Medicine, ISSN: 00221007 00221007
Jacqueline G. Perrigoue; Ji Li; Colby Zaph; Michael Goldschmidt; Phillip Scott; Frederic J. De Sauvage; Edward J. Pearce; Nico Ghilardi; David Artis
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Facilitating matched pairing and expression of TCR chains introduced into human T cells
Blood, ISSN: 00064971 00064971
Jürgen Kuball; Michelle L. Dossett; Matthias Wolfl; William Y. Ho; Ralf-Holger Voss; Carla Fowler; Philip D. Greenberg
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Robustness of a multivariate normal approximation for imputation of incomplete binary data
Statistics in Medicine, ISSN: 02776715 10970258
Coen A. Bernaards; Thomas R. Belin; Joseph L. Schafer
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Emi2 at the crossroads: Where CSF meets MPF
Cell Cycle, ISSN: 15514005 15384101
David V. Hansen; Joseph R. Pomerening; Matthew K. Summers; Julie J. Miller; James E. Ferrell Jr.; Peter K Jackson
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Translational unmasking of Emi2 directs cytostatic factor arrest in meiosis II
Cell Cycle, ISSN: 15514005 15384101
Jeffrey J. Tung; Kiran Padmanabhan; David V. Hansen; Joel D. Richter; Peter K Jackson
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Future of antibody purification
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, ISSN: 15700232
Duncan Low; O'Leary; Narahari Pujar
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Robo1 and Robo2 control the development of the lateral olfactory tract
Journal of Neuroscience, ISSN: 02706474 02706474
Coralie Fouquet; Thomas Di Meglio; Le Ma; Takahiko Kawasaki; Hua Long; Tatsumi Hirata; Marc Tessier-Lavigne; Alain Chedotal; Kim T. Nguyen-Ba-Charvet
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Large-scale identification of novel transcripts in the human genome
Genome Research, ISSN: 10889051 15495469
Brock A. Peters; Brad St. Croix; Tobias Sjöblom; Jordan M. Cummins; Natalie Silliman; Janine Ptak; Saurabh Saha; Kenneth W. Kinzler; Christos Hatzis; Victor E. Velculescu
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Synthesis and structure-activity relationship of N-acyl-Gly-, N-acyl-Sar- and N-blocked-boroPro inhibitors of FAP, DPP4, and POP
Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X
Thuy Tran; Quan; Conrad Yap Edosada; Mark Mayeda; Wiesmann; Daniel P. Sutherlin; Beni B. Wolf
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Antiangiogenesis to treat cancer and intraocular neovascular disorders
Laboratory Investigation, ISSN: 00236837 15300307
Farbod Shojaei; Napoleone Ferrara
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Sudden death in Prader-Willi syndrome: Brief review of five additional cases - Concerning the article by U. Eiholzer et al.: Deaths in children with Prader-Willi syndrome. A contribution to the debate about the safety of growth hormone treatment in children with PWS (Horm Res 2005;63:33-39)
Hormone Research, ISSN: 03010163
Bert Bakker; Thomas J. Maneatis; Barbara M. Lippe
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Comprehensive assesment of metabolic enzyme and transporter genes using the affymetrix® targeted genotyping system
Pharmacogenomics, ISSN: 14622416 17448042
Carmen M. Dumaual; Xin Miao; Thomas M. Daly; Carsten Bruckner; Reuben K. Njau; Dong-Jing Fu; Sandra Close-Kirkwood; Nancy L. Bauer; Nancy Watanabe; Paul Hardenbol; Richard D. Hockett
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A Role for Nogo Receptor in Macrophage Clearance from Injured Peripheral Nerve
Neuron, ISSN: 08966273
Elizabeth J. Fry; Carole Ho; Samuel David
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Infant care patterns at epidemiologic study of cystic fibrosis sites that achieve superior childhood lung function
Pediatrics, ISSN: 00314005 02105721
Raj Padman; Susanna A. McColley; Dave P. Miller; Michael W. Konstan; Morgan; Michael S. Schechter; Clement L. Ren; Wagener
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Loss of the BH3-only protein Bid does not rescue RelA-deficient embryos from TNF-R1-mediated fatal hepatocyte destruction [2]
Cell Death and Differentiation, ISSN: 13509047 14765403
Kaufmann; Gugasyan; Gerondakis; Vishva M. Dixit; Andreas Strasser
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Unified Manufacturing Control System (MCS) architecture for pharmaceutical and biotech manufacturing
Pharmaceutical Engineering, ISSN: 02738139
Ronald E. Menéndez; Darrell Tanner
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Hepatocyte growth factor activator inhibitor-1 (HAI-1) is essential for the integrity of basement membranes in the developing placental labyrinth
Developmental Biology, ISSN: 00121606
Bin Fan; Jane Brennan; Deanna Grant; Franklin V. Peale Jr.; Linda Rangell; Daniel Kirchhofer
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Current development of clinical inhibitors of poly(ADP-ribose) polymerase in oncology
Clinical Cancer Research, ISSN: 10780432
Kapila Ratnam; Low
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Cardiotrophin-1 is an essential factor in the natural defense of the liver against apoptosis
Hepatology, ISSN: 02709139
Juan M. Marquès; Idoia Belza; Bettina Holtmann; Diane Pennica; Jesús Prieto; Matilde Bustos
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Expression of protein elongation factor eEF1A2 predicts favorable outcome in breast cancer
Breast Cancer Research and Treatment, ISSN: 01676806
Geeta Kulkarni; Dmitry A. Turbin; Anahita Amiri; Sujeeve Jeganathan; Miguel A. Andrade-Navarro; Thomas D Wu; David G. Huntsman; Jonathan M. Lee
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Mice expressing a humanized form of VEGF-A may provide insights into the safety and efficacy of anti-VEGF antibodies
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Hans-Peter Gerber; Xiumin Wu; Lanlan Yu; Wiesmann; Xiao Huan Liang; Chingwei V. Lee; Fuh; Christine Olsson; Lisa A. Damico; David Xie; Meng; Johnny Gutierrez; Corpuz; Bing Li; Linda Hall; Linda Rangell; Ron Ferrando; Henry B. Lowman; Franklin V. Peale Jr.; Napoleone Ferrara
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Identification of IGF2 signaling through phosphoinositide-3-kinase regulatory subunit 3 as a growth-promoting axis in glioblastoma
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Liliana Soroceanu; Samir Kharbanda; Ruihuan Chen; Robert Soriano; Kenneth D. Aldape; Anjan Misra; Jiping Zha; William F. Forrest; Janice M. Nigro; Zora Modrusan; Burt G. Feuerstein; Phillips
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Eruptive papules during efalizumab (anti-CD11a) therapy of psoriasis vulgaris: A case series
BMC Dermatology, ISSN: 14715945
Michelle A. Lowes; Francesca Chamian; Maria V. Abello; Craig Leonardi; Wolfgang Dummer; Kim Papp; James G. Krueger
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Function Blocking Antibodies to Neuropilin-1 Generated from a Designed Human Synthetic Antibody Phage Library
Journal of Molecular Biology, ISSN: 00222836
Wei-Ching Liang; Dennis; Scott Stawicki; Yvan Chanthery; Qi Pan; Yongmei Chen; Eigenbrot; Jianping Yin; Alexander W. Koch; Xiumin Wu; Napoleone Ferrara; Anil Bagri; Marc Tessier-Lavigne; Ryan J. Watts; Yan Wu
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Efficacy and safety of single-agent pertuzumab (rhuMAb 2C4), a human epidermal growth factor receptor dimerization inhibitor, in castration-resistant prostate cancer after progression from taxane-based therapy
Journal of Clinical Oncology, ISSN: 0732183X
Agus; Christopher J. Sweeney; Michael J. Morris; David Mendelson; Douglas G. McNeel; Frederick R. Ahmann; Jin Wang; Mika K. Derynck; Kimmie Ng; Benjamin Lyons; David E. Allison; Michael W. Kattan; Scher
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Efficacy and safety of single-agent pertuzumab (rhuMAb 2C4), a human epidermal growth factor receptor dimerization inhibitor, in castration-resistant prostate cancer after progression from taxane-based therapy
Journal of Clinical Oncology, ISSN: 0732183X
David B. Agus; Christopher J. Sweeney; Michael J. Morris; David Mendelson; Douglas G. McNeel; Frederick R. Ahmann; Jin Wang; Mika K. Derynck; Kimmie Ng; Benjamin Lyons; David E. Allison; Michael W. Kattan; Scher
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The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis
Journal of Immunology, ISSN: 00221767
Susan Sa; Patricia A. Valdez; Jianfeng Wu; Kenneth Jung; Fiona Zhong; Linda Hall; Ian Kasman; Jane Winer; Zora Modrusan; Dimitry Danilenko; Wenjun Ouyang
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Ion exchange chromatography of antibody fragments
Biotechnology and Bioengineering, ISSN: 00063592 10970290
Anders Ljunglöf; Karol M. Lacki; Jay Mueller; Chithkala Harinarayan; Robert Van Reis; Fahrner; James M. Van Alstine
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Dr. Rosenfeld and colleagues reply [13]
New England Journal of Medicine, ISSN: 00284793 15334406
Philip J. Rosenfeld; David M. Brown; Susan Schneider
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Aspartate isomerization in the complementarity-determining regions of two closely related monoclonal antibodies
Biochemistry, ISSN: 00062960
Aditya A. Wakankar; Ronald T. Borchardt; Eigenbrot; Steven Shia; Y. John Wang; Steven J. Shire; Jun Liu
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Novel genomic effects of glucocorticoids in epidermal keratinocytes: Inhibition of apoptosis, interferon-γ pathway, and wound healing along with promotion of terminal differentiation
Journal of Biological Chemistry, ISSN: 1083351X 00219258
Olivera Stojadinovic; Brian Lee; Constantinos Vouthounis; Sasa Vukelic; Irena Pastar; Miroslav Blumenberg; Harold Brem; Marjana Tomic-Canic
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