Genentech: Publications

May 1, 2005

A monoclonal antibody that inhibits mouse tissue factor function [7]

Journal of Thrombosis and Haemostasis, ISSN: 15387933 15387836

Daniel Kirchhofer; Paul Moran; Sherron L. Bullens; Franklin V. Peale Jr.; Bunting

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May 1, 2005

GMAP: A genomic mapping and alignment program for mRNA and EST sequences

Bioinformatics, ISSN: 13674803

Thomas D Wu; Colin K. Watanabe

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May 1, 2005

Disulfide locked variants of factor VIIa with a restricted β-strand conformation have enhanced enzymatic activity

Protein Science, ISSN: 09618368

Henry R. Maun; Eigenbrot; Helga Raab; David Arnott; Lilian Phu; Sherron L. Bullens; Lazarus

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May 1, 2005

PAK4 mediates morphological changes through the regulation of GEF-H1

Journal of Cell Science, ISSN: 00219533

Marinella G. Callow; Sergey Zozulya; Mikhail L. Gishizky; Bahija Jallal; Tod Smeal

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May 1, 2005

Synthetic lethality of retinoblastoma mutant cells in the Drosophila eye by mutation of a novel peptidyl prolyl isomerase gene

Genetics, ISSN: 00166731

Kyle A. Edgar; Marcia Belvin; Annette L. Parks; Kellie Whittaker; Matt B. Mahoney; Monique Nicoll; Christopher C. Park; Christopher G. Winter; Feng Chen; Kim Lickteig; Ferhad Ahmad; Hanife Esengil; Matthew V. Lorenzi; Amanda Norton; Brent A. Rupnow; Laleh Shayesteh; Mariano Tabios; Lynn M. Young; Pamela M. Carroll; Casey Kopczynski; Greg D. Plowman; Lori S. Friedman; Helen L. Francis-Lang

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May 1, 2005

Tenecteplase in the treatment of thrombosed hemodialysis grafts

CardioVascular and Interventional Radiology, ISSN: 01741551

Abigail Falk; Kathy Harbour

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April 26, 2005

Comparison of the global structure and dynamics of native and unmodified tRNAval

Biochemistry, ISSN: 00062960

Annaleen Vermeulen; Scott A. McCallum; Arthur Pardi

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April 25, 2005

Non-enzymatic hinge region fragmentation of antibodies in solution

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, ISSN: 15700232

Cordoba; Bao-Jen Shyong; Deirdre Breen; Reed J. Harris

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April 15, 2005

Napoleone Ferrara discusses Avastin™ and the future of anti-angiogenesis therapy

Drug Discovery Today, ISSN: 13596446

Ulrike Knies-Bamforth; Christopher Watson; Napoleone Ferrara

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April 15, 2005

γδ T cell homeostasis is controlled by IL-7 and IL-15 together with subset-specific factors

Journal of Immunology, ISSN: 00221767

Roberto Baccala; Deborah Witherden; Rosana Gonzalez-Quintial; Wolfgang Dummer; Charles D. Surh; Wendy L. Havran; Argyrios N. Theofilopoulos

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April 1, 2005

Comparative evaluation of three active air samplers: For the monitoring of airborne microorganisms

Pharmaceutical Technology, ISSN: 15432521

Evelyn F. Der; Joe P. Stablein; Daniel A. Coleman

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April 1, 2005

Design, optimisation, and evaluation of a sheath flow interface for automated capillary electrophoresis-electrospray-mass spectrometry

Electrophoresis, ISSN: 01730835

Charles C. Liu; Jean-Francois Alary; Pauline Vollmerhaus; Miryam Kadkhodayan

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April 1, 2005

Increased hepatobiliary clearance of unconjugated thyroxine determines DMP 904-induced alterations in thyroid hormone homeostasis in rats

Toxicological Sciences, ISSN: 10966080

Harvey Wong; Lois D. Lehman-McKeeman; Mary F. Grubb; Grossman; Vasanthi M. Bhaskaran; Eric G. Solon; Helen S. Shen; Ronald J. Gerson; Bruce D. Car; Bitao Zhao; Brian Gemzik

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April 1, 2005

Population pharmacokinetics or efalizumab (humanized monoclonal anti-CD11a antibody) following long-term subcutaneous weekly dosing in psoriasis subjects

Journal of Clinical Pharmacology, ISSN: 00912700

Sun; Jian-Feng Lu; Amita Joshi; Peter Compton; Paul Kwon; Rene Bruno

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April 1, 2005

Defining molecular targets for drug design: Synergism between academia and industry

Journal of Pediatric Gastroenterology and Nutrition, ISSN: 02772116

Andrew A. Chan

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April 1, 2005

Method validation and measurement of biomarkers in nonclinical and clinical samples in drug development: A conference report

Pharmaceutical Research, ISSN: 07248741

Jean W. Lee; Russell Weiner; Jeff M. Sailstad; Ronald Bowsher; Dean W. Knuth; Peter J. O'Brien; Jean L. Fourcroy; Rakesh Dixit; Lini Pandite; Robert G. Pietrusko; Holly D. Soares; Quarmby; Ole L. Vesterqvist; David M. Potter; James L. Witliff; Herbert A. Fritche; Timothy O'Leary; Lorah Perlee; Sunil Kadam; John A. Wagner

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April 1, 2005

Intramolecular cooperativity in a protein binding site assessed by combinatorial shotgun scanning mutagenesis

Journal of Molecular Biology, ISSN: 00222836

Gábor Pál; Ultsch; Clark; Bridget Currell; Anthony A. Kossiakoff; Sachdev S. Sidhu

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April 1, 2005

Identification of a massive reserve of hematopoietic progenitors in mice

Stem Cells and Development, ISSN: 15473287

Hal E. Broxmeyer; Scott Cooper; Lasky; Frederic J. De Sauvage

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April 1, 2005

Safety and efficacy of intravitreal injection of ranibizumab in combination with verteporfin PDT on experimental choroidal neovascularization in the monkey

Archives of Ophthalmology, ISSN: 00039950

Deeba Husain; Ivana K. Kim; Danny Gauthier; Anne Marie Lane; Miltiadis K. Tsilimbaris; Eric Ezra; Edward Connolly; Norman Michaud; Evangelos S. Gragoudas; Charles A. O'Neill; Joseph Beyer; Joan W. Miller

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April 1, 2005

Multiple protein interactions involving proposed extracellular loop domains of the tight junction protein occludin

Molecular Biology of the Cell, ISSN: 10591524

Asma Nusrat; G. Thomas Brown; Jeffrey Tom; Alex Drake; Tam T.T. Bui; Quan; Mrsny

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April 1, 2005

Coregulator interactions with the thyroid hormone receptor

Molecular and Cellular Proteomics, ISSN: 15359476

Jamie M. R. Moore; R. Kiplin Guy

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March 28, 2005

Hepsin activates pro-hepatocyte growth factor and is inhibited by hepatocyte growth factor activator inhibitor-1B (HAI-1B) and HAI-2

FEBS Letters, ISSN: 00145793

Daniel Kirchhofer; Peek; Michael T. Lipari; Karen L Billeci; Bin Fan; Paul Moran

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March 25, 2005

Impact of multiple re-use of anion-exchange chromatography media on virus removal

Journal of Chromatography A, ISSN: 00219673

Lenore A Norling; Scott Lute; Rachel Emery; Wynn Khuu; Mark Voisard; Yuan Xu; Qi Chen; Gregory S. Blank; Kurt Brorson

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March 15, 2005

Cutting edge: Recent immune status determines the source of antigens that drive homeostatic T cell expansion

Journal of Immunology, ISSN: 00221767

William C. Kieper; Amy Troy; J. Theodore Burghardt; Chris Ramsey; Joon Youb Lee; Han-Qing Jiang; Wolfgang Dummer; Hao Shen; John J. Cebra; Charles D. Surh

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March 15, 2005

IL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes

Journal of Immunology, ISSN: 00221767

Katia Boniface; François-Xavier Bernard; Martine Garcia; Austin L. Gurney; Jean-Claude Lecron; Franck Morel

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March 11, 2005

A selective, slow binding inhibitor of factor VIIa binds to a nonstandard active site conformation and attenuates thrombus formation in vivo

Journal of Biological Chemistry, ISSN: 00219258 1083351X

Alan G. Olivero; Eigenbrot; Richard Goldsmith; Kirk D. Robarge; Dean R. Artis; Flygare; Thomas E. Rawson; Daniel P. Sutherlin; Saloumeh Kadkhodayan; Beresini; Linda O. Elliott; Geralyn G. Deguzman; David W. Banner; Ultsch; Ulla Marzec; Stephen R. Hanson; Refino; Bunting; Daniel Kirchhofer

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March 11, 2005

Conformational lability in serine protease active sites: Structures of hepatocyte growth factor activator (HGFA) alone and with the inhibitory domain from HGFA inhibitor-1B

Journal of Molecular Biology, ISSN: 00222836

Steven Shia; Jennifer Stamos; Daniel Kirchhofer; Bin Fan; Judy Wu; Corpuz; Santell; Lazarus; Eigenbrot

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March 7, 2005

T cells that cannot respond to TGF-β escape control by CD4+ CD25+ regulatory T cells

Journal of Experimental Medicine, ISSN: 00221007

Linda Fahlén; Simon Read; Leonid Gorelik; Stephen D. Hurst; Coffman; Richard A. Flavell; Fiona Powrie

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March 1, 2005

The mitochondrial inner membrane protein mitofilin controls cristae morphology

Molecular Biology of the Cell, ISSN: 10591524

George B. John; Yonglei Shang; Li Li; Christian Renken; Carmen A. Mannella; Jeanne M. L. Selker; Linda Rangell; Michael J. Bennett; Jiping Zha

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March 1, 2005

Effect of copper sulfate on performance of a serum-free CHO cell culture process and the level of free thiol in the recombinant antibody expressed

Biotechnology Progress, ISSN: 87567938

Wendy B. Chaderjian; Chin; Reed J. Harris; Etcheverry

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March 1, 2005

αvβ3 antagonists based on a central benzoic acid scaffold

Polish Journal of Chemistry, ISSN: 01375083

Will; Breipohl; Gourvest; Ruxer; Doucet; Auberval; Roland Baron; Gaillard; Thomas Gadek; Knolle; Stilz; Peyman

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March 1, 2005

1H, 13C, and 15N resonance assignments of SAP18 [1]

Journal of Biomolecular NMR, ISSN: 09252738

Scott A. McCallum; Jianping Yin; Wayne J. Fairbrother

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March 1, 2005

Pharmacokinetics and pharmacodynamics of multiple weekly subcutaneous efalizumab doses in patients with plaque psoriasis

Journal of Clinical Pharmacology, ISSN: 00912700

Deborah L. Mortensen; Patricia Walicke; Xiaolin Wang; Paul Kwon; Peter Kuebler; Alice Gottlieb; James G. Krueger; Craig Leonardi; Bruce Miller; Amita Joshi

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March 1, 2005

CD4+ T cell-mediated antigen-specific immunotherapy in a mouse model of cervical cancer

Cancer Research, ISSN: 00085472

Dylan Daniel; Christopher Chiu; Enrico Giraudo; Masahiro Inoue; Lee A. Mizzen; N. Randall Chu; Douglas Hanahan

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March 1, 2005

Efficacy of trastuzumab

Cancer Research, ISSN: 00085472

Charles L. Vogel; Josina C. Reddy; Leonard M. Reyno

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March 1, 2005

Mass spectrometric contributions to the practice of phosphorylation site mapping through 2003

Molecular and Cellular Proteomics, ISSN: 15359476

Kelly M. Loyet; Stults; David Arnott

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March 1, 2005

Vascular endothelial growth factor D is dispensable for development of the lymphatic system

Molecular and Cellular Biology, ISSN: 02707306

Megan E. Baldwin; Michael M. Halford; Sally Roufail; Richard A. Williams; Margaret L. Hibbs; Dianne Grail; Hajime Kubo; Steven A. Stacker; Marc G. Achen

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March 1, 2005

Peripheral nerve-derived VEGF promotes arterial differentiation via neuropilin 1-mediated positive feedback

Development (Cambridge), ISSN: 09501991

Yoh-Suke Mukouyama; Hans-Peter Gerber; Napoleone Ferrara; Chenghua Gu; David J. Anderson

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March 1, 2005

Proteomic profiling of surface proteins on Th1 and Th2 Cells

Journal of Proteome Research, ISSN: 15353893

Kelly M. Loyet; Wenjun Ouyang; Dan L. Eaton; Stults

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February 25, 2005

Structures of APRIL-receptor complexes: Like BCMA, TACI employs only a single cysteine-rich domain for high affinity ligand binding

Journal of Biological Chemistry, ISSN: 00219258

Sarah G. Hymowitz; Darshana Patel; Heidi J. A. Wallweber; Steven T. Runyon; Minhong Yan; Jianping Yin; Stephanie K. Shriver; Nathaniel C. Gordon; Borlan Pan; Nicholas J. Skelton; Robert F. Kelley; Melissa A. Starovasnik

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February 21, 2005

A phase I study of dexosome immunotherapy in patients with advanced non-small cell lung cancer

Journal of Translational Medicine, ISSN: 14795876 14795876

Michael A. Morse; Jennifer Garst; Takuya Osada; Shubi Khan; Amy Hobeika; Timothy M. Clay; Nancy Valente; Revati Shreeniwas; Mary Ann Sutton; Alain Delcayre; Di-Hwei Hsu; Jean-Bernard Le Pecq; H. Kim Lyerly

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February 18, 2005

Accumulation of free ADP-ribose from mitochondria mediates oxidative stress-induced gating of TRPM2 cation channels

Journal of Biological Chemistry, ISSN: 00219258

Anne-Laure Perraud; Christina L. Takanishi; Betty Shen; Shin Kang; Megan K. Smith; Carsten Schmitz; Heather M. Knowles; Dana Ferraris; Weixing Li; Jie Zhang; Barry L. Stoddard; Andrew M. Scharenberg

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February 17, 2005

Differential requirement for Plexin-A3 and -A4 in mediating responses of sensory and sympathetic neurons to distinct class 3 Semaphorins

Neuron, ISSN: 08966273

Avraham Yaron; Pei-Hsin Huang; Hwai-Jong Cheng; Marc Tessier-Lavigne

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February 16, 2005

Triple knock-out of CNTF, LIF, and CT-1 defines cooperative and distinct roles of these neurotrophic factors for motoneuron maintenance and function

Journal of Neuroscience, ISSN: 02706474

Bettina Holtmann; Stefan Wiese; Mohtashem Samsam; Katja Grohmann; Diane Pennica; Rudolf Martini; Michael Sendtner

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February 15, 2005

Semi-parametric and non-parametric methods for clinical trials with incomplete data

Statistics in Medicine, ISSN: 02776715

O'Brien; David Zhang; Kent R. Bailey

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February 1, 2005

Pharmacology and pharmacodynamics of bevacizumab as monotherapy or in combination with cytotoxic therapy in preclinical studies

Cancer Research, ISSN: 00085472

Hans-Peter Gerber; Napoleone Ferrara

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February 1, 2005

Characterization of alteplase (tPA) following delivery through the AngioJet rheolytic catheter

Journal of Endovascular Therapy, ISSN: 15266028

Charles P. Semba; Weck; Mahmood K Razavi; Cindy M. Setum; Thomas W. Patapoff

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February 1, 2005

The FIP3-Rab11 protein complex regulates recycling endosome targeting to the cleavage furrow during late cytokinesis

Molecular Biology of the Cell, ISSN: 10591524

Gayle M. Wilson; Andrew B. Fielding; Glenn C. Simon; Xinzi Yu; Paul D. Andrews; Rebecca S. Haines; Andrew M. Frey; Andrew A. Peden; Gwyn W. Gould; Rytis Prekeris

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February 1, 2005

Review: Clonidine is more effective than placebo for long term smoking cessation, but has side effects

Evidence-Based Medicine, ISSN: 13565524

Steven G. Gourlay; Stead; Neal L. Benowitz; Charles J. Bentz

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February 1, 2005

Nitration and increased α-synuclein expression associated with dopaminergic neurodegeneration in equine pituitary pars intermedia dysfunction

Journal of Neuroendocrinology, ISSN: 09538194

Dianne McFarlane; Noel Dybdal; Donaldson; Lisa M. Miller; Alastair E. Cribb

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