Genentech: Publications

February 1, 2005

Preclinical pharmacokinetics of ranibizumab (rhuFabV2) after a single intravitreal administration

Investigative Ophthalmology and Visual Science, ISSN: 01460404

Jacques Gaudreault; David T.W. Fei; Jeriza Rusit; Pamela Suboc; Vanessa Shiu

January 25, 2005

A coreceptor interaction between the CD28 and TNF receptor family members B and T lymphocyte attenuator and herpesvirus entry mediator

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Lino C. Gonzalez Jr.; Kelly M. Loyet; Jill Calemine-Fenaux; Vandana Chauhan; Bernd Wranik; Wenjun Ouyang; Dan L. Eaton

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January 25, 2005

Genetic deletion of the Nogo receptor does not reduce neurite inhibition in vitro or promote corticospinal tract regeneration in vivo

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Binhai Zheng; Jasvinder K. Atwal; Carole Ho; Lauren C Case; Xiao-Lin He; Garcia; Oswald Steward; Marc Tessier-Lavigne

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January 25, 2005

Automated online liquid chromatographic/mass spectrometric metabolic study for prodrug stability

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, ISSN: 15700232

Fran Lai; S. Cyrus Khojasteh

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January 21, 2005

Receptor-selective mutants of apoptosis-inducing ligand 2/tumor necrosis factor-related apoptosis-inducing ligand reveal a greater contribution of Death Receptor (DR) 5 than DR4 to apoptosis signaling

Journal of Biological Chemistry, ISSN: 00219258

Robert F. Kelley; Klara Totpal; Stephanie H. Lindstrom; Mary Mathieu; Karen L Billeci; Laura DeForge; Roger Pai; Sarah G. Hymowitz; Avi Ashkenazi

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January 15, 2005

Importance of cellular microenvironment and circulatory dynamics in B cell immunotherapy

Journal of Immunology, ISSN: 00221767

Qian Gong; Qinglin Ou; Shiming Ye; Wyne P. Lee; Jennine Cornelius; Laurie Diehl; Yu Lin Wei; Zhilan Hu; Yanmei Lu; Yongmei Chen; Yan Wu; Meng; Gribling; Zhonghua Lin; Kathy Nguyen; Thanhvien Tran; Yifan Zhang; Hugh Rosen; Flavius Martin; Andrew A. Chan

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January 1, 2005

Influence of different hormonal regimens on endometrial microvascular density and VEGF expression in women suffering from breakthrough bleeding

Human Reproduction, ISSN: 14602350 02681161

Peter A.W. Rogers; Martinez; Girling; Lederman; Cann; Farrell; Tresserra; Patel

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January 1, 2005

A role for Hath1, a bHLH transcription factor, in colon adenocarcinoma

Annals of the New York Academy of Sciences, ISSN: 00778923

Ching Ching Leow; Paul G. Polakis; Gao

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January 1, 2005

Vascular endothelial growth factor expression in the retinal pigment epithelium is essential for choriocapillaris development and visual function

American Journal of Pathology, ISSN: 00029440

Alexander G. Marneros; Jie Fan; Yoshihito Yokoyama; Hans-Peter Gerber; Napoleone Ferrara; Rosalie K. Crouch; Bjorn R. Olsen

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January 1, 2005

Isolated central nervous system metastases in patients with HER2-overexpressing advanced breast cancer treated with first-line trastuzumab-based therapy

Annals of Oncology, ISSN: 15698041 09237534

Burstein; Lieberman; Dennis J. Slamon; Eric P. Winer; Pam Klein

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January 1, 2005

Development and validation of the cystic fibrosis questionnaire in the United States: A health-related quality-of-life measure for cystic fibrosis

Chest, ISSN: 00123692

Alexandra L. Quittner; Anne Buu; Melissa A. Messer; Avani C. Modi; Marc Watrous

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January 1, 2005

Cancer risk in asthmatic populations

Annals of Allergy, Asthma and Immunology, ISSN: 10811206

Patricia Tennis; Beth Sherrill; Carlos Fernandez; Chantal M. Dolan

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January 1, 2005

Regeneration of the adult central nervous system.

Current Biology, ISSN: 09609822

Lauren C Case; Marc Tessier-Lavigne

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January 1, 2005

Oligosaccharide release and MALDI-TOF MS analysis of N-linked carbohydrate structures from glycoproteins.

Methods in Molecular Biology, ISSN: 10643745

Rodney Keck; Briggs; Andrew J.S. Jones

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January 1, 2005

Capillary electrophoresis of carbohydrates derivatized with fluorophoric compounds.

Methods in Molecular Biology, ISSN: 10643745

Stacey Ma; Wendy Lau; Rodney Keck; Briggs; Andrew J.S. Jones; Kathy Moorhouse; Wassim Nashabeh

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January 1, 2005

Reversible self-association increases the viscosity of a concentrated monoclonal antibody in aqueous solution

Journal of Pharmaceutical Sciences, ISSN: 00223549

Jun Liu; Mary D. H. Nguyen; Andya; Steven J. Shire

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January 1, 2005

Total serum IgE levels in a large cohort of patients with severe or difficult-to-treat asthma

Annals of Allergy, Asthma and Immunology, ISSN: 10811206

Larry Borish; Bradley E. Chipps; Yamo Deniz; Gujrathi; Zheng; Chantal M. Dolan

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January 1, 2005

Hormone receptor status does not affect the clinical benefit of trastuzumab therapy for patients with metastatic breast cancer

Clinical Breast Cancer, ISSN: 15268209

Adam Brufsky; Barry Lembersky; Kathy Schiffman; Lieberman; Virginia Paton

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January 1, 2005

Good research practices for cost-effectiveness analysis alongside clinical trials: The ISPOR RCT-CEA Task Force report

Value in Health, ISSN: 10983015

Scott D. Ramsey; Richard Willke; Andrew Briggs; Ruth Brown; Martin Buxton; Chawla; John Cook; Henry Glick; Bengt Liljas; Diana Petitti; Shelby Reed

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January 1, 2005

PDA Technical Report No. 42: Process validation of protein manufacturing

PDA Journal of Pharmaceutical Science and Technology, ISSN: 10797440

Chris Bussineau; Robert Seely; Genevieve Lovitt; James Fernandez; Gregory S. Blank; Brandreth; Doris Conrad; Rebecca A. Devine; Robert J. Ferris; Koen De Heyder; Robert W. Juffras; Peter Levy; Wolfgang List; Morten Munk; Brian C. Neely; Stephen Notarnicola; O'Leary; Harold Van Deinse

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January 1, 2005

Incidence of infection during efalizumab therapy for psoriasis: Analysis of the clinical trial experience

Clinical Therapeutics, ISSN: 1879114X 01492918

Richard G. B. Langley; Wayne Carey; Elyse S. Rafal; Stephen K. Tyring; Ivor Caro; Xiaolin Wang; Graham Wetherill; Kenneth B. Gordon

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January 1, 2005

Arming antibodies for cancer therapy

Current Opinion in Pharmacology, ISSN: 14714892

Paul G. Polakis

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January 1, 2005

Development of a quantifiable symptom assessment tool for patients with chronic bronchitis: The Chronic Bronchitis Symptoms Assessment Scale

COPD: Journal of Chronic Obstructive Pulmonary Disease, ISSN: 15412563 15412555

David H. Au; David Blough; Leonard Kirchdoerfer; Kevin B.. Weiss; Edmunds M. Udris; Sean D. Sullivan

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January 1, 2005

Single-molecule studies of synaptotagmin and complexin binding to the SNARE complex

Biophysical Journal, ISSN: 00063495

Mark E. Bowen; Keith Weninger; James A. Ernst; Steven Chu; Axel T. Brünger

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January 1, 2005

A brief review of the use and utility of growth hormone stimulation testing in the NCGS: Do we need to do provocative GH testing?

Growth Hormone and IGF Research, ISSN: 15322238 10966374

Wilson; James W. Frane

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January 1, 2005

Uniform overexpression and rapid accessibility of α5β 1 integrin on blood vessels in tumors

American Journal of Pathology, ISSN: 00029440

Patricia Parsons-Wingerter; Ian Kasman; Scott Norberg; Anette Magnussen; Sara Zanivan; Alberto Rissone; Peter Baluk; Cecile J. Favre; Ursula Jeffry; Richard Murray; Donald M. McDonald

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January 1, 2005

Maximum tolerated dose of a humanized anti-vascular endothelial growth factor antibody fragment for treating neovascular age-related macular degeneration

Ophthalmology, ISSN: 01616420

Philip J. Rosenfeld; Steven D. Schwartz; Mark S. Blumenkranz; Joan W. Miller; Julia A. Haller; Reimann; William L. Greene; Naveed Shams

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January 1, 2005

Depletion of B cells by a humanized anti-CD20 antibody PRO70769 in Macaca Fascicularis

Journal of Immunotherapy, ISSN: 15249557

Yulia Vugmeyster; Joseph Beyer; Howell; Dan Combs; Fielder; Yang; Ferhan Qureshi; Bryan Sandlund; Ly Kawaguchi; Wolfgang Dummer; Henry B. Lowman; Kathleen McKeever

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January 1, 2005

Met activation and receptor dimerization in cancer: A role for the Sema domain

Cell Cycle, ISSN: 15514005 15384101

Dineli Wickramasinghe; Monica Kong-Beltran

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January 1, 2005

Epidemiology of cystic fibrosis-related diabetes

Journal of Pediatrics, ISSN: 00223476

Marshall; Butler; Stoddard; Moran; Liou; Morgan; Seema Asthana

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January 1, 2005

Adjuvant and neoadjuvant therapy in non-small cell lung cancer

Seminars in Oncology, ISSN: 00937754

Chandra P. Belani

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January 1, 2005

Proteomic profiling of recombinant Escherichia coli in high-cell-density fermentations for improved production of an antibody fragment biopharmaceutical

Applied and Environmental Microbiology, ISSN: 00992240

Ilana S. Aldor; Denise C. Krawitz; William F. Forrest; Christina Y. Chen; Julie C. Nishihara; John C. Joly; Kathleen M. Champion

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January 1, 2005

Alteplase as a catheter locking solution: In vitro evaluation of biochemical stability and antimicrobial properties

Journal of Vascular and Interventional Radiology, ISSN: 10510443

Weck; Samantha Cheung; Hiraoka-Sutow; Thomas W. Patapoff; Charles P. Semba

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January 1, 2005

Alteplase stability and bioactivity after low-power ultrasonic energy delivery with the OmniSonics resolution system

Journal of Vascular and Interventional Radiology, ISSN: 10510443

John Smikahl; Yeung; Sharon Wang; Charles P. Semba

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January 1, 2005

The anti-inflammatory effects of omalizumab confirm the central role of IgE in allergic inflammation

Journal of Allergy and Clinical Immunology, ISSN: 00916749

Stephen Holgate; Thomas B. Casale; Sally E. Wenzel; Jean Bousquet; Yamo Deniz; Colin Reisner

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January 1, 2005

Industry-based medical communications: Benchmarking survey of quality assurance practices

Drug Information Journal, ISSN: 00928615

S. Justin Hileman; Graham; Joyce Serrano Martin; Barry Grobman

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January 1, 2005

Are inflammatory cytokines the common link between cancer-associated cachexia and depression?

Journal of Supportive Oncology, ISSN: 15446794

James Illman; Robert Corringham; Don Robinson Jr.; Hugh M. Davis; Jean-Francois Rossi; Cella; Mohit Trikha

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January 1, 2005

The changing role of thrombolytic therapy in the management of acute deep vein thrombosis

Therapy, ISSN: 14750708

Mahmood K Razavi; Charles P. Semba

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January 1, 2005

Efficacy and safety observed during 24 weeks of efalizumab therapy in patients with moderate to severe plaque psoriasis

Archives of Dermatology, ISSN: 0003987X

Alan Menter; Kenneth B. Gordon; Wayne Carey; Tiffani K. Hamilton; Scott Glazer; Ivor Caro; Nicole F. Li; Wayne P. Gulliver

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January 1, 2005

Gradient projection algorithms and software for arbitrary rotation criteria in factor analysis

Educational and Psychological Measurement, ISSN: 00131644

Coen A. Bernaards; Robert I. Jennrich

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January 1, 2005

The role of VEGF in the regulation of physiological and pathological angiogenesis.

EXS, ISSN: 1023294X

Napoleone Ferrara

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January 1, 2005

POLO kinase regulates the Drosophila centromere cohesion protein MEI-S332

Developmental Cell, ISSN: 15345807

Astrid S. Clarke; Tracy Tzu-Ling Tang; Danny Liang-Yee Ooi; Terry L. Orr-Weaver

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January 1, 2005

Engineering ML-IAP to produce an extraordinarily potent caspase 9 inhibitor: Implications for Smac-dependent anti-apoptotic activity of ML-IAP

Biochemical Journal, ISSN: 02646021

Domagoj Vucic; Matthew C Franklin; Heidi J. A. Wallweber; Kanad Das; Brendan P. Eckelman; Hwain Shin; Linda O. Elliott; Saloumeh Kadkhodayan; Deshayes; Guy S. Salvesen; Wayne J. Fairbrother

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January 1, 2005

Comparison of EP "Heavy Metals" test with USP "Conductivity" test

Pharmaceutical Technology, ISSN: 15432521

George Torres; Arlene Arsitio; Carole Genovesi

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January 1, 2005

Evaluation of clinical outcomes according to HER2 detection by fluorescence in situ hybridization in women with metastatic breast cancer treated with trastuzumab

Clinical Breast Cancer, ISSN: 15268209

Robert Mass; Michael F. Press; Steven M. Anderson; Melody A. Cobleigh; Charles L. Vogel; Noel Dybdal; Grazyna Leiberman; Dennis J. Slamon; Virginia Paton

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January 1, 2005

Mouse Disp1 is required in sonic hedgehog-expressing cells for paracrine activity of the cholesterol-modified ligand

Development (Cambridge), ISSN: 09501991

Hua Tian; Juhee Jeong; Brian D. Harfe; Clifford J. Tabin; Andrew P. McMahon

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January 1, 2005

Trials in the real world

Good Clinical Practice Journal, ISSN: 13500961

Elizabeth Tschosik; Susan Morris

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January 1, 2005