Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 10701 - 10750 OF 15217 RESULTS

January 1, 2004

Inhibitors of histone deacetylases promote hematopoietic stem cell self-renewal

Cytotherapy, ISSN: 14653249

Judy Young; Wu; Hansteen; Du; Sambucetti; Remiszewski; O'Farrell; Hill; Lavau; Lesley J. Murray

January 1, 2004

Re: Catheter-directed Thrombolytic Therapy for Limb Ischemia: Current Status and Controversies [1]

Journal of Vascular and Interventional Radiology, ISSN: 10510443

Charles P. Semba; Iris Tam; Martha Blaney

January 1, 2004

Bevacizumab (Avastin).

Clinical journal of oncology nursing, ISSN: 10921095

Gena Middleton; Denise V Lapka

January 1, 2004

Quality Assurance Practices for Pharmaceutical Industry-Based Drug Information Departments: A Review and Case Study

Therapeutic Innovation and Regulatory Science, ISSN: 21684790

Stacey M. Fung; Joyce Serrano Martin

January 1, 2004

Ureagenesis: Evidence for a lack of hepatic regulation of acid-base equilibrium in humans

American Journal of Physiology - Renal Physiology, ISSN: 15221466 1931857X

Markus Hosch; Juergen Muser; Henry N. Hulter; Reto Krapf

December 22, 2003

Cup is an eIF4E binding protein required for both the translational repression of oskar and the recruitment of Barentsz

Journal of Cell Biology, ISSN: 00219525

James E. Wilhelm; Meredith Hilton; Quinlan Amos; William J. Henzel

December 20, 2003

Application of Multivirus Spike Approach for Viral Clearance Evaluation

Biotechnology and Bioengineering, ISSN: 00063592

Christine Valera; Janice W. Chen; Yuan Xu

December 17, 2003

Efalizumab for Patients with Moderate to Severe Plaque Psoriasis: A Randomized Controlled Trial

JAMA - Journal of the American Medical Association, ISSN: 00987484

Kenneth B. Gordon; Kim Papp; Tiffani K. Hamilton; Patricia Walicke; Wolfgang Dummer; Nicole F. Li; Bresnahan; Alan Menter

December 15, 2003

Activation of Toll-Like Receptor 2 on Human Tracheobronchial Epithelial Cells Induces the Antimicrobial Peptide Human β Defensin-2

Journal of Immunology, ISSN: 00221767

Cheryl J. Hertz; Qi Wu; Edith Martin Porter; Yan J. Zhang; Karl-Heinz Weismüller; Godowski; Tomas Ganz; Scott H. Randell; Robert L. Modlin

December 12, 2003

Anterior-Posterior Guidance of Commissural Axons by Wnt-Frizzled Signaling

Science, ISSN: 00368075

Anna I. Lyuksyutova; Chin-Chun Lu; Nancy Milanesio; Leslie A. King; Nini Guo; Yanshu Wang; Jeremy Nathans; Marc Tessier-Lavigne; Yimin Zou

December 9, 2003

IL-27 regulates IL-12 responsiveness of naïve CD4+ T cells through Stat1-dependent and -independent mechanisms

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Sophie Lucas; Nico Ghilardi; Ji Li; Frederic J. De Sauvage

December 4, 2003

IGF-I Receptor Mutations Resulting in Intrauterine and Postnatal Growth Retardation

New England Journal of Medicine, ISSN: 00284793

M. Jennifer Abuzzahab; Anke Schneider; Goddard; Florin Grigorescu; Corinne Lautier; Eberhard Keller; Wieland Kiess; Jürgen Klammt; Jürgen Kratzsch; Doreen Osgood; Roland Pfäffle; Klemens Raile; Berthold Seidel; Robert J. Smith; Chernausek

December 1, 2003

Regulation of interactions of endotoxin with host cells

Journal of Endotoxin Research, ISSN: 09680519

Theresa L. Gioannini; Athmane Teghanemt; Kol A. Zarember; Weiss

December 1, 2003

Underlying chronic granulomatous disease in a patient with bronchocentric granulomatosis

Thorax, ISSN: 00406376

Moltyaner; Geerts; Chamberlain; Heyworth; Noack; Julie Rae; Doyle; Downey

December 1, 2003

Nonlinear models for repeated measurement data: An overview and update

Journal of Agricultural, Biological, and Environmental Statistics, ISSN: 10857117

Davidian; Giltinan

December 1, 2003

The netrin-G1 ligand NGL-1 promotes the outgrowth of thalamocortical axons

Nature Neuroscience, ISSN: 10976256

John C. Lin; Ho; Austin L. Gurney; Rosenthal

December 1, 2003

Hair Cell Development in Higher Vertebrates

Current Topics in Developmental Biology, ISSN: 00702153

Gao

December 1, 2003

B cell defects in SLP65/BLNK-deficient mice can be partially corrected by the absence of CD22, an inhibitory coreceptor for BCR signaling

European Journal of Immunology, ISSN: 00142980

Judith Gerlach; Snigdha Ghosch; Hassan Jumaa; Michael Reth; Jürgen Wienands; Andrew A. Chan; Lars Nitschke

December 1, 2003

Identification of the human cytochrome P450s responsible for the in vitro metabolism of a leukotriene B4 receptor antagonist, CP-195,543

Xenobiotica, ISSN: 00498254

S. Cyrus Khojasteh; Rossulek; Fouda; Chandra Prakash

December 1, 2003

Generation of Fine Powders of Recombinant Human Deoxyribonuclease Using the Aerosol Solvent Extraction System

Pharmaceutical Research, ISSN: 07248741

Rana T. Bustami; Chan; Sweeney; Fariba Dehghani; Neil R. Foster

December 1, 2003

Semi-synthetic glycopeptide antibacterials

Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X

J. Kevin Judice; John Pace

December 1, 2003

VEGF and bone

Journal of Musculoskeletal Neuronal Interactions, ISSN: 11087161

Ellen H. Filvaroff

December 1, 2003

Angiogenesis: New opportunities and solutions for drug development. Predictive markers for antiangiogenic drugs

Expert Opinion on Investigational Drugs, ISSN: 13543784

Hans-Peter Gerber

November 28, 2003

Stanniocalcin 1 Is an Autocrine Modulator of Endothelial Angiogenic Responses to Hepatocyte Growth Factor

Journal of Biological Chemistry, ISSN: 00219258

Constance Zlot; Gladys S. Ingle; Hongo; Suya Yang; Zhong Sheng; Ralph H. Schwall; Nicholas F. Paoni; Fay Wang; Franklin V. Peale Jr.; Mary E. Gerritsen

November 28, 2003

Deficiency of the Nrf1 and Nrf2 Transcription Factors Results in Early Embryonic Lethality and Severe Oxidative Stress

Journal of Biological Chemistry, ISSN: 00219258

Laura Leung; Mandy Kwong; Stephen Hou; Candy Lee; Jefferson Y. Chan

November 28, 2003

Regulation of NF-κB-Dependent Lymphocyte Activation and Development by Paracaspase

Science, ISSN: 00368075

Astrid A. Ruefli-Brasse; French; Vishva M. Dixit

November 27, 2003

A New Synthetic Approach to the C Ring of Known as Well as Novel Bryostatin Analogues

Organic Letters, ISSN: 15237060

Paul A. Wender; Michael F. T. Koehler; Martin Sendzik

November 24, 2003

Systematic identification of regulatory proteins critical for T-cell activation

Journal of Biology, ISSN: 14785854 14754924

Peter C. Chu; Jorge Pardo; Haoran Zhao; Connie C. Li; Erlina Pali; Mary M. Shen; Kunbin Qu; Simon X. Yu; Betty Huang; Peiwen Yu; Esteban S. Masuda; Susan M. Molineaux; Frank Kolbinger; Gregorio Aversa; Jan De Vries; Donald G. Payan; X. Charlene Liao

November 20, 2003

A Novel Targeted T-Cell Modulator, Efalizumab, for Plaque Psoriasis

New England Journal of Medicine, ISSN: 00284793

Mark Lebwohl; Stephen K. Tyring; Tiffani K. Hamilton; Darryl P. Toth; Scott Glazer; Naji H. Tawfik; Patricia Walicke; Wolfgang Dummer; Xiaolin Wang; Marvin Garovoy; David M. Pariser

November 13, 2003

Assembling Polycyclic Bisguanidine Motifs Resembling Batzelladine Alkaloids by Double Tethered Biginelli Condensations

Organic Letters, ISSN: 15237060

Frederick Cohen; Shawn K. Collins; Larry E. Overman

November 13, 2003

A rapid cellular FRET assay of polyglutamine aggregation identifies a novel inhibitor

Neuron, ISSN: 08966273

Sonia K. Pollitt; Judit Pallos; Jieya Shao; Urvee A. Desai; Aye Aye K. Ma; Leslie Michels Thompson; J. Lawrence Marsh; Marc I. Diamond

November 7, 2003

Non-Receptor Protein Tyrosine Kinases in T-Cell Antigen Receptor Function

Handbook of Cell Signaling,

Kiminori Hasegawa; Shin W. Kang; Chris Chiu; Andrew A. Chan

November 7, 2003

Hedgehog Signaling and Embryonic Development

Handbook of Cell Signaling,

Mark Merchant; Weilan Ye; Frederic J. De Sauvage

November 7, 2003

The Mechanism of VEGFR Activation Suggested by the Complex of VEGF-flt1-D2

Handbook of Cell Signaling,

Wiesmann; De Vos

November 7, 2003

What Does the Structure of Apo2L/TRAIL Bound to DR5 Tell Us About Death Receptors?

Handbook of Cell Signaling,

Sarah G. Hymowitz; De Vos

November 7, 2003

Mammalian Brain Morphogenesis and Midline Axon Guidance Require Heparan Sulfate

Science, ISSN: 00368075

Masaru Inatani; Fumitoshi Irie; Andrew Plump; Marc Tessier-Lavigne; Yu Yamaguchi

November 7, 2003

The Mechanism of NGF Suggested by the NGF-TrkA-D5 Complex

Handbook of Cell Signaling,

De Vos; Wiesmann

November 7, 2003

Signaling from FGF Receptors in Development and Disease

Handbook of Cell Signaling,

Monica Kong-Beltran; Daniel J. Donoghue

November 6, 2003

Confronting the challenges of bioprocess control in an industrial setting

Proceedings of the American Control Conference, ISSN: 07431619

Tina M. Larson

November 1, 2003

Improved gene transfer selectivity to hepatocarcinoma cells by retrovirus vector displaying single-chain variable fragment antibody against c-Met

Cancer Gene Therapy, ISSN: 09291903

Tuan Huy Nguyen; Nathalie Loux; Ibrahim Dagher; Corinne Vons; Kendall Carey; Pascale Briand; Michelle Hadchouel; Dominique Franco; Jacqueline Jouanneau; Ralph H. Schwall; Anne Weber

November 1, 2003

SNAP-25 Ser187 does not mediate phorbol ester enhancement of hippocampal synaptic transmission

Neuropharmacology, ISSN: 00283908

Finley; Richard H. Scheller; Daniel V. Madison

November 1, 2003

In Vitro Activity of TD-6424 against Staphylococcus aureus

Antimicrobial Agents and Chemotherapy, ISSN: 00664804

John Pace; Kevin M. Krause; Deborah Johnston; Dmitri Debabov; Terry X. Wu; Lesley Farrington; Cassie Lane; Deborah L. Higgins; Burton G. Christensen; J. Kevin Judice; Koné Kaniga

November 1, 2003

Growth Hormone (GH) Dose-Response in Young Adults with Childhood-Onset GH Deficiency: A Two-Year, Multicenter, Multiple-Dose, Placebo-Controlled Study

Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X

Louis E. Underwood; Kenneth M. Attie; Joyce Baptista

November 1, 2003

Critical Role of the Complement System in Group B Streptococcus-Induced Tumor Necrosis Factor Alpha Release

Infection and Immunity, ISSN: 00199567

Ofer Levy; Rochelle M. Jean-Jacques; Colette Cywes; Richard B. Sisson; Kol A. Zarember; Godowski; Jennifer L. Christianson; Hilde-Kari Guttormsen; Michael C. Carroll; Anne Nicholson-Weller; Michael R. Wessels

November 1, 2003

Angiogenesis and bone repair

Drug Discovery Today, ISSN: 13596446

Richard A. D. Carano; Ellen H. Filvaroff

October 28, 2003

A Mutation Causing a Reduced Level of Expression of Six β4-Galactosyltransferase Genes Is the Basis of the Lec19 CHO Glycosylation Mutant

Biochemistry, ISSN: 00062960

JaeHoon Lee; Sung-Hae Park; Subha Sundaram; T. Shantha Raju; Nancy L. Shaper; Pamela Stanley

October 24, 2003

Diagnostic growth hormone deficiency testing practices among patients in the NCGS/NCSS databases

Journal of Pediatric Endocrinology and Metabolism, ISSN: 0334018X

Richard A. Levy; Connelly

October 24, 2003

Near adult heights after growth hormone treatment in patients with idiopathic short stature or idiopathic growth hormone deficiency

Journal of Pediatric Endocrinology and Metabolism, ISSN: 0334018X

J. Paul Frindik; Stephen F. Kemp; Joanne Julius Hunold

October 20, 2003

Generic/matrix evaluation of SV40 clearance by anion exchange chromatography in flow-through mode

Biotechnology and Bioengineering, ISSN: 00063592

Sherrie Curtis; Kitty Lee; Gregory S. Blank; Kurt Brorson; Yuan Xu

October 15, 2003

Cortical and retinal defects caused by dosage-dependent reductions in VEGF-A paracrine signaling

Developmental Biology, ISSN: 00121606

Jody Haigh; Paula I. Morelli; Holger Gerhardt; Katharina Haigh; John Tsien; Annette Damert; Lucile Miquerol; Ulrich Muhlner; Rüdiger Klein; Napoleone Ferrara; Wagner; Christer Betsholtz; Andras Nagy

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