Genentech: Publications

October 10, 2003

A neurexin-related protein, BAM-2, terminates axonal branches in C. elegans

Science, ISSN: 00368075

Antonio Colavita; Marc Tessier-Lavigne

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October 8, 2003

Validity and realiability of patient reported outcomes used in psoriasis: Results from two randomized clinical trials

Health and Quality of Life Outcomes, ISSN: 14777525

Richard Shikiar; Bresnahan; Stephen P. Stone; Christine Thompson; John Y. Koo; Dennis A. Revicki

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October 1, 2003

Crystal structures of the benzene and ethanol solvates of neotame

Journal of Chemical Crystallography, ISSN: 10741542

Zedong Dong; Victor G. Young Jr.; Eric Munson; Steve A. Schroeder; Indra Prakash; David J. W. Grant

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October 1, 2003

Emerging technologies that overcome biological barriers for therapeutic protein delivery

Expert Opinion on Biological Therapy, ISSN: 14712598

Daugherty; Mrsny

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October 1, 2003

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: A bioinformatics assessment

Genome Research, ISSN: 10889051

Hilary F. Clark; Austin L. Gurney; Evangeline Abaya; Kevin Baker; Daryl T. Baldwin; Brush; Jian Chen; Bernard Chow; Clarissa Chui; Crowley; Bridget Currell; Bethanne Deuel; Patrick Dowd; Dan L. Eaton; Foster; Grimaldi; Qimin Gu; Hass; Sherry Heldens; Arthur Huang; Hok Seon Kim; Laura Klimowski; Yisheng Jin; Stephanie Johnson; James Lee; Lhney Lewis; Dong-Zhou Liao; Melanie R Mark; Edward Robbie; Celina Sanchez; Schoenfeld; Somasekar Seshagiri; Laura C. Simmons; Singh; Victoria Smith; Stinson; Alicia Vagts; Richard L. Vandlen; Colin K. Watanabe; David Wieand; Kathryn Woods; Xie; Yansura; Sothy Yi; Guoying Yu; Jean Q. Yuan; Min Zhang; Zemin Zhang; Goddard; William I. Wood; Godowski

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October 1, 2003

Population pharmacokinetics and pharmacodynamics of enoxaparin in unstable angina and non-ST-segment elevation myocardial infarction

British Journal of Clinical Pharmacology, ISSN: 03065251

Rene Bruno; Pascale Baille; Sylvie Retout; Nicole Vivier; Christine Veyrat-Follet; Ger-Jan Sanderink; Richard C. Becker; Elliott M. Antman

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October 1, 2003

EG-VEGF and Bv8: A novel family of tissue-selective mediators of angiogenesis, endothelial phenotype, and function

Trends in Cardiovascular Medicine, ISSN: 10501738

Jennifer Lecouter; Napoleone Ferrara

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September 26, 2003

Comprehensive mutagenesis of the C-terminal domain of the M13 gene-3 minor coat protein: The requirements for assembly into the bacteriophage particle

Journal of Molecular Biology, ISSN: 00222836

Gregory A. Weiss; Tomer A. Roth; Pierre F. Baldi; Sachdev S. Sidhu

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September 19, 2003

Contributions of CDR3 to VHH domain stability and the design of monobody scaffolds for naive antibody libraries

Journal of Molecular Biology, ISSN: 00222836

Christopher J. Bond; James C. Marsters Jr.; Sachdev S. Sidhu

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September 19, 2003

Tissue expression, protease specificity, and Kunitz domain functions of hepatocyte growth factor activator inhibitor-1B (HAI-1B), a new splice variant of HAI-1

Journal of Biological Chemistry, ISSN: 00219258

Daniel Kirchhofer; Peek; Wei Li; Jennifer Stamos; Eigenbrot; Saloumeh Kadkhodayan; J. Michael Elliott; Corpuz; Lazarus; Paul Moran

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September 18, 2003

The function role of GATA-3 in Th1 and Th2 differentiation

Immunologic Research, ISSN: 0257277X

Meixia Zhou; Wenjun Ouyang

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September 15, 2003

Genome-wide identification of chromosomal regions of increased tumor expression by transcriptome analysis

Cancer Research, ISSN: 00085472

Yan Zhou; Shiuh-Ming Luoh; Yan Zhang; Colin K. Watanabe; Thomas D Wu; Michael Ostland; William I. Wood; Zemin Zhang

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September 15, 2003

Plasmin activates the lymphangiogenic growth factors VEGF-C and VEGF-D

Journal of Experimental Medicine, ISSN: 00221007

Bradley K. McColl; Megan E. Baldwin; Sally Roufail; Craig Freeman; Robert L. Moritz; Pichard J. Simpson; Kari Alitalo; Steven A. Stacker; Marc G. Achen

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September 12, 2003

Prostaglandin E2 regulates cell migration via the intracellular activation of the epidermal growth factor receptor

Journal of Biological Chemistry, ISSN: 00219258

F. Gregory Buchanan; Dingzhi Wang; Francesca Bargiacchi; Raymond N. DuBois

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September 5, 2003

The functional binding epitope of a high affinity variant of human growth hormone mapped by shotgun alanine-scanning mutagenesis: Insights into the mechanisms responsible for improved affinity

Journal of Molecular Biology, ISSN: 00222836

Gábor Pál; Anthony A. Kossiakoff; Sachdev S. Sidhu

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September 1, 2003

Shedding light on bioscience. Symposium on optical imaging: Applications to biology and medicine

EMBO Reports, ISSN: 1469221X

Mary J. Cole; Melinda Pirity; Anna-Katerina Hadjantonakis

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September 1, 2003

An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors

Molecular Cell, ISSN: 10972765

Antony W. Burgess; Hyun-Soo Cho; Eigenbrot; Kathryn M. Ferguson; Thomas P.J. Garrett; Daniel J. Leahy; Mark A. Lemmon; Mark X. Sliwkowski; Colin W. Ward; Shigeyuki Yokoyama

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September 1, 2003

Superwarfarin and glass ingestion with prolonged coagulopathy requiring high-dose vitamin K1 therapy

Pharmacotherapy, ISSN: 02770008

Ben T. Tsutaoka; Michael Miller; Stacey M. Fung; Manish M. Patel; Kent R. Olson

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September 1, 2003

ABRF-PRG03: Phosphorylation site determination

Journal of Biomolecular Techniques, ISSN: 15240215 19434731

David Arnott; Mary Ann Gawinowicz; Raymond A. Grant; Thomas A. Neubert; Len C. Packman; Kaye D. Speicher; Kathryn Stone; Christoph W. Turck

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September 1, 2003

Bacteriophage that display small molecules

Chemistry and Biology, ISSN: 10745521

Frederic A. Fellouse; Deshayes

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August 26, 2003

Relation between hospital intra-aortic balloon counterpulsation volume and mortality in acute myocardial infarction complicated by cardiogenic shock

Circulation, ISSN: 00097322

Edmond W. Chen; John G. Canto; Lori Parsons; Eric D. Peterson; Katherine A. Littrell; Nathan R. Every; C.Michael Gibson; Judith S. Hochman; E. Magnus Ohman; Morris Cheeks; Hal V. Barron

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August 15, 2003

Photodetachment of hydrated oxalate dianions in the gas phase, C 2O42-(H2O)n (n-3-40): From solvated clusters to nanodroplet

Journal of Chemical Physics, ISSN: 00219606

Xue-Bin Wang; Xin Yang; John B. Nicholas; Lai-Sheng Wang

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August 12, 2003

Complex with a phage display-derived peptide provides insight into the function of insulin-like growth factor I

Biochemistry, ISSN: 00062960

Schaffer; Deshayes; Nakamura; Sachdev S. Sidhu; Nicholas J. Skelton

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August 11, 2003

Dynamics of cell surface molecules during T cell recognition

Annual Review of Biochemistry, ISSN: 00664154

Mark M. Davis; Michelle Krogsgaard; Johannes B. Huppa; Cenk Sumen; Marco A. Purbhoo; Darrell J. Irvine; Lawren C. Wu; Lauren Ehrlich

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August 8, 2003

Structural insight into how an anti-idiotypic antibody against D3H44 (anti-tissue factor antibody) restores normal coagulation

Journal of Molecular Biology, ISSN: 00222836

Eigenbrot; Meng; Rajeswari Krishnamurthy; Michael T. Lipari; Presta; Devaux; Wong; Paul Moran; Sherron L. Bullens; Daniel Kirchhofer

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August 8, 2003

The forkhead transcription factor FOXO4 induces the down-regulation of hypoxia-inducible factor 1α by a von Hippel-Lindau protein-independent mechanism

Journal of Biological Chemistry, ISSN: 00219258

Tracy Tzu-Ling Tang; Lasky

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August 1, 2003

The effects of an anti-CD11a mAb, efalizumab, on allergen-induced airway responses and airway inflammation in subjects with atopic asthma

Journal of Allergy and Clinical Immunology, ISSN: 00916749

Gauvreau; Allan B. Becker; Boulet; Jamila Chakir; Robert B. Fick Jr.; William L. Greene; Killian; O'Byrne; John K. Reid; Cockcroft

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August 1, 2003

Electron and excitation transfer in hetero-supramolecular assemblies and at molecule-nanoparticle interfaces

Pure and Applied Chemistry, ISSN: 00334545

Piotrowiak; Deshayes; Romanova; Cynthia Pagba; Sarmimala Hore; Giovanni Zordan; Ileana Place; Agnes Farrán

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August 1, 2003

Quantitative analysis of colorectal tissue microarrays by immunofluorescence and in situ hybridization

Journal of Pathology, ISSN: 00223417

Adrian M. Jubb; Landon; Jennifer Burwick; Thinh Q. Pham; Gretchen D. Frantz; Cairns; Philip Quirke; Franklin V. Peale Jr.; Kenneth J. Hillan

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August 1, 2003

Comparison of neural network, Bayesian, and multiple stepwise regression-based limited sampling models to estimate area under the curve

Pharmacotherapy, ISSN: 02770008

Chee Ng

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August 1, 2003

The hypoxic response of tumors is dependent on their microenvironment

Cancer Cell, ISSN: 15356108

Barbara Blouw; Hanqiu Song; Tarik Tihan; Jenel Bosze; Napoleone Ferrara; Hans-Peter Gerber; Randall S. Johnson; Gabriele Bergers

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July 15, 2003

Structure and function analysis of peptide antagonists of melanoma inhibitor of apoptosis (ML-IAP)

Biochemistry, ISSN: 00062960

Matthew C Franklin; Saloumeh Kadkhodayan; Heidi J. A. Wallweber; Daniela Alexandru; Mark D. Distefano; Linda O. Elliott; Flygare; Grace Mausisa; David C Okawa; Danny Ong; Domagoj Vucic; Deshayes; Wayne J. Fairbrother

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July 15, 2003

Mice lacking the CARD of CARMA1 exhibit defective B lymphocyte development and impaired proliferation of their B and T lymphocytes

Current Biology, ISSN: 09609822

Kim Newton; Vishva M. Dixit

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July 7, 2003

Trail/Apo2L

The Cytokine Handbook,

David H. Lynch; Avi Ashkenazi

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July 2, 2003

Early use of glycoprotein IIb/IIIa inhibitors in non-ST-elevation acute myocardial infarction: Observations from the national registry of myocardial infarction 4

Journal of the American College of Cardiology, ISSN: 07351097

Eric D. Peterson; Charles V. Pollack Jr.; Matthew T. Roe; Lori Parsons; Katherine A. Littrell; John G. Canto; Hal V. Barron

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July 1, 2003

Structural basis of the interaction between RalA and Sec5, a subunit of the sec6/8 complex

EMBO Journal, ISSN: 02614189

Shuya Fukai; Hugo T. Matern; Jagath R. Junutula; Richard H. Scheller; Axel T. Brünger

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July 1, 2003

Comparison of the Escherichia coli proteomes for recombinant human growth hormone producing and nonproducing fermentations

Proteomics, ISSN: 16159853

Kathleen M. Champion; Julie C. Nishihara; Ilana S. Aldor; G. Tony Moreno; Dana C. Andersen; Kathy L. Stults; Vanderlaan

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July 1, 2003

Nrf1 is critical for redox balance and survival of liver cells during development

Molecular and Cellular Biology, ISSN: 02707306

Linyun Chen; Mandy Kwong; Ronghua Lu; David G. Ginzinger; Candy Lee; Laura Leung; Jefferson Y. Chan

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July 1, 2003

Cooperation of cytokine signaling with chimeric transcription factors in leukemogenesis: PML-retinoic acid receptor alpha blocks growth factor-mediated differentiation

Molecular and Cellular Biology, ISSN: 02707306

Vernon T. Phan; David B. Shultz; Bao-Tran Truong; Timothy J. Blake; Anna L. Brown; Thomas J. Gonda; Michelle M. Le Beau; Scott C. Kogan

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July 1, 2003

Production of the signalling molecule, autoinducer-2, by Neisseria meningitidis: Lack of evidence for a concerted transcriptional response

Microbiology, ISSN: 13500872

Joanne E. Dove; Kazutoyo Yasukawa; Colin R. Tinsley; Xavier Nassif

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July 1, 2003

Automated sample preparation using vapor-phase hydrolysis for amino acid analysis

Analytical Biochemistry, ISSN: 00032697

Alan Higbee; Susan C. Wong; William J. Henzel

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July 1, 2003

Cooperation of cytokine signaling with chimeric transcription factors in leukemogenesis: PML-retinoic acid receptor alpha blocks growth factor-mediated differentiation

Molecular and Cellular Biology, ISSN: 02707306

Vernon T. Phan; David B. Shultz; Bao-Tran Truong; Timothy J. Blake; Anna L. Brown; Thomas J. Gonda; Michelle M. Le Beau; Scott Kogan

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June 26, 2003

Neutropenia in patients treated with rituximab [6] (multiple letters)

New England Journal of Medicine, ISSN: 00284793

Eric Voog; Morschhauser; Philippe Solal-Celigny; Benyunes; Pratik S. Multani; Andrew Saunders

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June 26, 2003

Interstitial pneumonitis related to rituximab therapy [5] (multiple letters)

New England Journal of Medicine, ISSN: 00284793

Catherine Burton; Richard Kaczmarski; Riaz Jan-Mohamed; Benyunes; Pratik S. Multani; Andrew Saunders

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June 23, 2003

Bolus inhalation of rhDNAse with the AERx system in subjects with cystic fibrosis

Journal of Aerosol Medicine: Deposition, Clearance, and Effects in the Lung, ISSN: 08942684

David E. Geller; John Thipphawong; Babatunde Otulana; Daniel Caplan; Dawn Ericson; Laura Milgram; Jerry Okikawa; Joanne M. Quan; C. Michael Bowman

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June 17, 2003

Redesigning an antibody fragment for faster association with its antigen

Biochemistry, ISSN: 00062960

Jonathan S. Marvin; Henry B. Lowman

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June 17, 2003

Role of VEGF-A in vascularization of pancreatic islets

Current Biology, ISSN: 09609822

Eckhard Lammert; Guoqiang Gu; Margaret McLaughlin; Dennis Brown; Rolf Brekken; Lewis Charles Murtaugh; Hans-Peter Gerber; Napoleone Ferrara; Douglas A. Melton

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June 15, 2003

Discovery of small molecule leads in a biotechnology datastream

Drug Discovery Today, ISSN: 13596446

Thomas Gadek; Robert S. McDowell

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June 13, 2003

Engineering exosite peptides for complete inhibition of factor VIIa using a protease switch with substrate phage

Journal of Biological Chemistry, ISSN: 00219258

Henry R. Maun; Eigenbrot; Lazarus

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June 5, 2003

A highly selective, non-hydantoin, non-carboxylic acid inhibitor of aldose reductase with potent oral activity in diabetic rat models: 6-(5-chloro-3-methylbenzofuran-2-sulfonyl)-2-H-pyridazin-3-one

Journal of Medicinal Chemistry, ISSN: 00222623

Mylari; Sandra J. Armento; Beebe; Edward L. Conn; Coutcher; Dina; Melissa T. O'Gorman; Michael C. Linhares; William H. Martin; Oates; David A. Tess; Gregory J. Withbroe; Zembrowski

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