Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 10801 - 10850 OF 15217 RESULTS

The magnitude of hedgehog signaling activity defines skin tumor phenotype
EMBO Journal, ISSN: 02614189
Vladimir Grachtchouk; Marina Grachtchouk; Lori Lowe; Tim Johnson; Lebing Wei; Aiqin Wang; Frederic J. De Sauvage; Andrzej A. Dlugosz
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Diabetic patients and retinal proliferation: An evaluation of the role of vascular endothelial growth factor (VEGF)
Experimental and Clinical Endocrinology and Diabetes, ISSN: 09477349
Nicoletti; Nicoletti; Napoleone Ferrara; Meli; Reibaldi; Alfredo Reibaldi
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Robust generation of new hair cells in the mature mammalian inner ear by adenoviral expression of Hath1
Molecular and Cellular Neuroscience, ISSN: 10447431
Shou; Zheng; Gao
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Recombinant human thrombopoietin augments mobilization of peripheral blood progenitor cells for autologous transplantation
Biology of Blood and Marrow Transplantation, ISSN: 10838791
Charles Linker; Paolo Anderlini; Herzig; Neal Christiansen; Somlo; William Bensinger; Fay; Joseph P. Lynch; Lawrence T. Goodnough; Ashby; Benyunes; Jones Jr.; Timothy A. Yang; Langdon L. Miller; Charles Weaver
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Mouse endocrine gland-derived vascular endothelial growth factor: A distinct expression pattern from its human ortholog suggests different roles as a regulator of organ-specific angiogenesis
Endocrinology, ISSN: 00137227
Jennifer Lecouter; Rui Lin; Gretchen D. Frantz; Zemin Zhang; Kenneth J. Hillan; Napoleone Ferrara
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Strategies and methods in the identification of antagonists of protein-protein interactions
BioTechniques, ISSN: 07366205
Thomas Gadek
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The biology of VEGF and its receptors
Nature Medicine, ISSN: 10788956
Napoleone Ferrara; Hans-Peter Gerber; Jennifer Lecouter
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Differential expression of the angiogenic factor genes vascular endothelial growth factor (VEGF) and endocrine gland-derived VEGF in normal and polycystic human ovaries
American Journal of Pathology, ISSN: 00029440
Napoleone Ferrara; Gretchen D. Frantz; Jennifer Lecouter; Lisa Dillard-Telm; Thinh Q. Pham; Aparna Draksharapu; Thomas Giordano; Franklin V. Peale Jr.
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Pathogenesis of mucous cell metaplasia in a murine asthma model
American Journal of Pathology, ISSN: 00029440
J. Rachel Reader; Tepper; Edward S. Schelegle; Melinda C. Aldrich; Lei F. Putney; Juergen W. Pfeiffer; Dallas M. Hyde
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BAFF/BLyS receptor 3 comprises a minimal TNF receptor-like module that encodes a highly focused ligand-binding site
Biochemistry, ISSN: 00062960
Nathaniel C. Gordon; Borlan Pan; Sarah G. Hymowitz; Jianping Yin; Robert F. Kelley; Andrea G Cochran; Minhong Yan; Vishva M. Dixit; Wayne J. Fairbrother; Melissa A. Starovasnik
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Inhibition of epithelial ductal branching in the prostate by sonic hedgehog is indirectly mediated by stromal cells
Journal of Biological Chemistry, ISSN: 00219258
Bu-Er Wang; Shou; Ross; Koeppen; Frederic J. De Sauvage; Gao
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TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells
EMBO Journal, ISSN: 02614189
Andreas Gschwind; Stefan Hart; Oliver M. Fischer; Axel Ullrich
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Phosphate ester serum albumin affinity tags greatly improve peptide half-life in vivo
Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X
Zobel; Michael F. T. Koehler; Beresini; Lisa D. Caris; Dan Combs
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Bracketed generic inactivation of rodent retroviruses by low pH treatment for monoclonal antibodies and recombinant proteins
Biotechnology and Bioengineering, ISSN: 00063592
Kurt Brorson; Sherrie Krejci; Kitty Lee; Elizabeth Hamilton; Kathryn Stein; Yuan Xu
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Activation and regulation of Toll-like receptors 2 and 1 in human leprosy
Nature Medicine, ISSN: 10788956
Stephan R. Krutzik; Maria Teresa Ochoa; Peter A. Sieling; Satoshi Uematsu; Yolanda W. Ng; Annaliza Legaspi; Philip T. Liu; Stewart T. Cole; Godowski; Yumi Maeda; Euzenir N. Sarno; Michael V. Norgard; Patrick J. Brennan; Shizuo Akira; Thomas H. Rea; Robert L. Modlin
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Inhibition of tissue factor limits the growth of venous thrombus in the rabbit
Journal of Thrombosis and Haemostasis, ISSN: 15387933 15387836
Jacques Himber; Wohlgensinger; Roux; Lisa A. Damico; John T. Fallon; Daniel Kirchhofer; Nemerson; Markus A. Riederer
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Pharmacokinetic study of patients with follicular or mantle cell lymphoma treated with rituximab as 'in vivo purge' and consolidative immunotherapy following autologous stem cell transplantation
Annals of Oncology, ISSN: 09237534
Joy Mangel; Rena Buckstein; Imrie; Spaner; Franssen; Pavlin; Boudreau; Pennell; Dan Combs; Neil Berinstein
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Vascular endothelial growth factor (VEGF) receptor-2 signaling mediates VEGF-CΔNΔC- and VEGF-A-induced angiogenesis in vitro
Experimental Cell Research, ISSN: 00144827
Jean-Christophe Tille; Xueyan Wang; Kenneth E. Lipson; Gerald McMahon; Napoleone Ferrara; Zhu; Daniel J. Hicklin; Jonathan P. Sleeman; Ulf Eriksson; Kari Alitalo; Pepper
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Design, construction, and in vitro analyses of multivalent antibodies
Journal of Immunology, ISSN: 00221767
Kathy Miller; Meng; Jun Liu; Amy Hurst; Vanessa Hsei; Wai Lee T. Wong; Rene Ekert; David Lawrence; Steve Sherwood; Laura DeForge; Jacques Gaudreault; Gilbert-Andre Keller; Mark X. Sliwkowski; Avi Ashkenazi; Presta
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Subcutaneously administered efalizumab (anti-CD11a) improves signs and symptoms of moderate to severe plaque psoriasis
Journal of Cutaneous Medicine and Surgery, ISSN: 12034754
Alice Gottlieb; Bruce Miller; Nicholas Lowe; William Shapiro; Charles Hudson; Ross Bright; Mark Ling; Anna Magee; Calvin O. McCall; Toivo Rist; Wolfgang Dummer; Patricia Walicke; Bauer; Mark White; Marvin Garovoy
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Sharing publication-related data and materials: Responsibilities of authorship in the life sciences
Plant Physiology, ISSN: 00320889
Thomas R. Cech; Sean R. Eddy; David Eisenberg; Karen Hersey; Steven H. Holtzman; George H. Poste; Natasha V. Raikhel; Richard H. Scheller; David B. Singer; Mary C. Waltham
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Functional consequences of a gene duplication and fusion event in an arginine kinase
Journal of Experimental Biology, ISSN: 00220949
Deanne M. Compaan; W. Ross Ellington
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Recombinant humanized anti-CD40 monoclonal antibody triggers autologous antibody-dependent cell-mediated cytotoxicity against multiple myeloma cells
British Journal of Haematology, ISSN: 00071048
Toshiaki Hayashi; Treon; Hideshima; Tai; Masaharu Akiyama; Paul Richardson; Chauhan; Iqbal S. Grewal; Anderson
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Anti-angiogenesis: Biology is the foundation for therapy
Drug Discovery Today, ISSN: 13596446
Hans-Peter Gerber
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DNA-dependent acetylation of p53 by the transcription coactivator p300
Journal of Biological Chemistry, ISSN: 00219258
David Dornan; Harumi Shimizu; Neil D. Perkins; Ted R. Hupp
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Extended spectrum of HIV-1 reverse transcriptase mutations in patients receiving multiple nucleoside analog inhibitors
AIDS, ISSN: 02699370
Matthew J. Gonzales; Thomas D Wu; Jonathan Taylor; Ilana Belitskaya; Rami Kantor; Dennis Israelski; Sunwen Chou; Andrew R. Zolopa; W. Jeffrey Fessel; Robert W. Shafer
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Identification of a phosphothionate analogue of lysophosphatidic acid (LPA) as a selective agonist of the LPA3 receptor
Journal of Biological Chemistry, ISSN: 00219258
Yutaka Hasegawa; James R. Erickson; Graham J. Goddard; Shuangxing Yu; Shuying Liu; Kwai Wa Cheng; Astrid Eder; Koji Bandoh; Junken Aoki; Renata Jarosz; Andrew D. Schrier; Kevin R. Lynch; Gordon B. Mills; Xianjun Fang
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Mutation patterns and structural correlates in human immunodeficiency virus type 1 protease following different protease inhibitor treatments
Journal of Virology, ISSN: 0022538X
Thomas D Wu; Celia A. Schiffer; Matthew J. Gonzales; Jonathan Taylor; Rami Kantor; Sunwen Chou; Dennis Israelski; Andrew R. Zolopa; W. Jeffrey Fessel; Robert W. Shafer
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Effects of annealing lyophilized and spray-lyophilized formulations of recombinant human interferon-γ
Journal of Pharmaceutical Sciences, ISSN: 00223549
Serena D. Webb; Cleland; John F. Carpenter; Theodore W. Randolph
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Ethics and the AIDS pandemic in the developing world
Journal of the International Association of Physicians in AIDS Care, ISSN: 15451097 15570886
Mark J. Ahn; Ashraf Grimwood; Heidi Schwarzwald; Allen Herman
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Asparagine deamidation in recombinant human lymphotoxin: Hindrance by three-dimensional structures
Journal of Pharmaceutical Sciences, ISSN: 00223549
Minli Xie; Shahrokh; Miryam Kadkhodayan; William J. Henzel; Powell; Ronald T. Borchardt; Richard L. Schowen
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Caspases signal not only apoptosis but also antigen-induced activation in cells of the immune system
Genes and Development, ISSN: 08909369
Kim Newton; Andreas Strasser
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Tenecteplase: Stability and bioactivity of thawed or diluted solutions used in peripheral thrombolysis
Journal of Vascular and Interventional Radiology, ISSN: 10510443
Charles P. Semba; Weck; Mahmood K Razavi; Lisa Tuomi; Thomas W. Patapoff
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N-benzoyl amino acids as LFA-1/ICAM inhibitors 1: Amino acid structure-activity relationship
Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X
Burdick; Kenneth J. Paris; Kenneth J Weese; Mark S. Stanley; Beresini; Clark; Robert S. McDowell; James C. Marsters Jr.; Thomas Gadek
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The VIVA trial: Vascular endothelial growth factor in ischemia for vascular angiogenesis
Circulation, ISSN: 00097322
Timothy D. Henry; Brian H. Annex; George McKendall; Michael A. Azrin; John J. Lopez; Frank J. Giordano; Shah; James T. Willerson; Raymond L. Benza; Daniel S. Berman; C.Michael Gibson; Alex Bajamonde; Amy Chen Rundle; Jennifer T. Fine; Edward R. McCluskey
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Type-I interferon receptor deficiency reduces lupus-like disease in NZB mice
Journal of Experimental Medicine, ISSN: 00221007
Marie-Laure Santiago-Raber; Roberto Baccala; Katarina M. Haraldsson; Divaker Choubey; Stewart; Dwight H. Kono; Argyrios N. Theofilopoulos
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Nucleic acid capture assay, a new method for direct quantitation of nucleic acids
Nucleic Acids Research, ISSN: 13624962
Siao Ping Tsai; Anne Wong; Elaine Mai; Pamela Chan; Grace Mausisa; Vasser; Jhurani; Mogens H. Jakobsen; Wai Lee T. Wong; Jean-Philippe Stephan
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HIF-1α is essential for myeloid cell-mediated inflammation
Cell, ISSN: 00928674
Thorsten Cramer; Yuji Yamanishi; Björn E. Clausen; Irmgard Förster; Rafal Pawlinski; Nigel Mackman; Volker H. Haase; Rudolf Jaenisch; Maripat Corr; Victor Nizet; Gary S. Firestein; Hans-Peter Gerber; Napoleone Ferrara; Randall S. Johnson
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The endocrine-gland-derived VEGF homologue Bv8 promotes angiogenesis in the testis: Localization of Bv8 receptors to endothelial cells
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Jennifer Lecouter; Rui Lin; Max L. Tejada; Gretchen D. Frantz; Franklin V. Peale Jr.; Kenneth J. Hillan; Napoleone Ferrara
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A crucial role of CD4 T cells as a functional source of CD154 in the initiation of insulin-dependent diabetes mellitus in the non-obese diabetic mouse
International Immunology, ISSN: 09538178
Koji Eshima; Conchi Mora; F. Susan Wong; E. Allison Green; Iqbal S. Grewal; Richard A. Flavell
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A randomized controlled trial evaluating the efficacy and safety of intermittent 3-, 4-, and 5-day cycles of intravenous recombinant human interleukin-2 combined with antiretroviral therapy (ART) versus ART alone in HIV-seropositive patients with 100-300 CD4+ T cells
Clinical Immunology, ISSN: 15216616
Alberdina W. De Boer; Norman Markowitz; H.Clifford Lane; Louis D. Saravolatz; Susan L. Koletar; Haig Donabedian; Carl Yoshizawa; A-M. Duliege; Gwendolyn Fyfe; Ronald T. Mitsuyasu
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Intravenous mouse infection model for studying the pathology of Enterococcus faecalis infections
Infection and Immunity, ISSN: 00199567
Claudia Gentry-Weeks; Monica Estay; Cindy Loui; Dale Baker
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α-1-acid glycoprotein as an independent predictor for treatment effects and a prognostic factor of survival in patients with non-small cell lung cancer treated with docetaxel
Clinical Cancer Research, ISSN: 10780432
Rene Bruno; Robert Olivares; Jocelyne Berille; Philip Chaikin; Nicole Vivier; Luz Hammershaimb; Gerald R. Rhodes; James R. Rigas
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Selective cyclin-dependent kinase 2/cyclin A antagonists that differ from ATP site inhibitors block tumor growth
Cancer Research, ISSN: 00085472
Nerissa Mendoza; Fong; James C. Marsters Jr.; Koeppen; Ralph H. Schwall; Dineli Wickramasinghe
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Origins of PDZ domain ligand specificity. Structure determination and mutagenesis of the erbin PDZ domain
Journal of Biological Chemistry, ISSN: 00219258
Nicholas J. Skelton; Michael F. T. Koehler; Zobel; Wai Lee T. Wong; Sherry Yeh; Pisabarro; Jianping Yin; Lasky; Sachdev S. Sidhu
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High-throughput protein sequencing
Analytical Chemistry, ISSN: 00032700
Victoria Pham; Jake Tropea; Suzy Wong; James Quach; William J. Henzel
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Inhibition of human papilloma virus E2 DNA binding protein by covalently linked polyamides
Nucleic Acids Research, ISSN: 03051048
Thomas D. Schaal; William Mallet; Dustin McMinn; Nam V. Nguyen; Michelle M. Sopko; Sam John; Bhavin S. Parekh
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Angiogenesis-independent endothelial protection of liver: Role of VEGFR-1
Science, ISSN: 00368075
Jennifer Lecouter; Dirk R. Moritz; Bing Li; Gail L. Phillips; Xiao Huan Liang; Hans-Peter Gerber; Kenneth J. Hillan; Napoleone Ferrara
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Mutations in the exocyst component Sec5 disrupt neuronal membrane traffic, but neurotransmitter release persists
Neuron, ISSN: 08966273
Mala Murthy; Dan Garza; Richard H. Scheller; Thomas L. Schwarz
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A profile hidden Markov model for signal peptides generated by HMMER
Bioinformatics, ISSN: 13674803
Zemin Zhang; William I. Wood
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