Genentech: Publications

November 27, 2003

A New Synthetic Approach to the C Ring of Known as Well as Novel Bryostatin Analogues

Organic Letters, ISSN: 15237060

Paul A. Wender; Michael F. T. Koehler; Martin Sendzik

November 24, 2003

Systematic identification of regulatory proteins critical for T-cell activation

Journal of Biology, ISSN: 14785854 14754924

Peter C. Chu; Jorge Pardo; Haoran Zhao; Connie C. Li; Erlina Pali; Mary M. Shen; Kunbin Qu; Simon X. Yu; Betty Huang; Peiwen Yu; Esteban S. Masuda; Susan M. Molineaux; Frank Kolbinger; Gregorio Aversa; Jan De Vries; Donald G. Payan; X. Charlene Liao

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November 20, 2003

A Novel Targeted T-Cell Modulator, Efalizumab, for Plaque Psoriasis

New England Journal of Medicine, ISSN: 00284793

Mark Lebwohl; Stephen K. Tyring; Tiffani K. Hamilton; Darryl P. Toth; Scott Glazer; Naji H. Tawfik; Patricia Walicke; Wolfgang Dummer; Xiaolin Wang; Marvin Garovoy; David M. Pariser

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November 13, 2003

A rapid cellular FRET assay of polyglutamine aggregation identifies a novel inhibitor

Neuron, ISSN: 08966273

Sonia K. Pollitt; Judit Pallos; Jieya Shao; Urvee A. Desai; Aye Aye K. Ma; Leslie Michels Thompson; J. Lawrence Marsh; Marc I. Diamond

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November 13, 2003

Assembling Polycyclic Bisguanidine Motifs Resembling Batzelladine Alkaloids by Double Tethered Biginelli Condensations

Organic Letters, ISSN: 15237060

Frederick Cohen; Shawn K. Collins; Larry E. Overman

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November 7, 2003

Signaling from FGF Receptors in Development and Disease

Handbook of Cell Signaling,

Monica Kong-Beltran; Daniel J. Donoghue

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November 7, 2003

The Mechanism of NGF Suggested by the NGF-TrkA-D5 Complex

Handbook of Cell Signaling,

De Vos; Wiesmann

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November 7, 2003

Mammalian Brain Morphogenesis and Midline Axon Guidance Require Heparan Sulfate

Science, ISSN: 00368075

Masaru Inatani; Fumitoshi Irie; Andrew Plump; Marc Tessier-Lavigne; Yu Yamaguchi

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November 7, 2003

What Does the Structure of Apo2L/TRAIL Bound to DR5 Tell Us About Death Receptors?

Handbook of Cell Signaling,

Sarah G. Hymowitz; De Vos

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November 7, 2003

The Mechanism of VEGFR Activation Suggested by the Complex of VEGF-flt1-D2

Handbook of Cell Signaling,

Wiesmann; De Vos

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November 7, 2003

Hedgehog Signaling and Embryonic Development

Handbook of Cell Signaling,

Mark Merchant; Weilan Ye; Frederic J. De Sauvage

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November 7, 2003

Non-Receptor Protein Tyrosine Kinases in T-Cell Antigen Receptor Function

Handbook of Cell Signaling,

Kiminori Hasegawa; Shin W. Kang; Chris Chiu; Andrew A. Chan

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November 6, 2003

Confronting the challenges of bioprocess control in an industrial setting

Proceedings of the American Control Conference, ISSN: 07431619

Tina M. Larson

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November 1, 2003

Angiogenesis and bone repair

Drug Discovery Today, ISSN: 13596446

Richard A. D. Carano; Ellen H. Filvaroff

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November 1, 2003

Critical Role of the Complement System in Group B Streptococcus-Induced Tumor Necrosis Factor Alpha Release

Infection and Immunity, ISSN: 00199567

Ofer Levy; Rochelle M. Jean-Jacques; Colette Cywes; Richard B. Sisson; Kol A. Zarember; Godowski; Jennifer L. Christianson; Hilde-Kari Guttormsen; Michael C. Carroll; Anne Nicholson-Weller; Michael R. Wessels

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November 1, 2003

Growth Hormone (GH) Dose-Response in Young Adults with Childhood-Onset GH Deficiency: A Two-Year, Multicenter, Multiple-Dose, Placebo-Controlled Study

Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X

Louis E. Underwood; Kenneth M. Attie; Joyce Baptista

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November 1, 2003

In Vitro Activity of TD-6424 against Staphylococcus aureus

Antimicrobial Agents and Chemotherapy, ISSN: 00664804

John Pace; Kevin M. Krause; Deborah Johnston; Dmitri Debabov; Terry X. Wu; Lesley Farrington; Cassie Lane; Deborah L. Higgins; Burton G. Christensen; J. Kevin Judice; Koné Kaniga

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November 1, 2003

SNAP-25 Ser187 does not mediate phorbol ester enhancement of hippocampal synaptic transmission

Neuropharmacology, ISSN: 00283908

Finley; Richard H. Scheller; Daniel V. Madison

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November 1, 2003

Improved gene transfer selectivity to hepatocarcinoma cells by retrovirus vector displaying single-chain variable fragment antibody against c-Met

Cancer Gene Therapy, ISSN: 09291903

Tuan Huy Nguyen; Nathalie Loux; Ibrahim Dagher; Corinne Vons; Kendall Carey; Pascale Briand; Michelle Hadchouel; Dominique Franco; Jacqueline Jouanneau; Ralph H. Schwall; Anne Weber

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October 28, 2003

A Mutation Causing a Reduced Level of Expression of Six β4-Galactosyltransferase Genes Is the Basis of the Lec19 CHO Glycosylation Mutant

Biochemistry, ISSN: 00062960

JaeHoon Lee; Sung-Hae Park; Subha Sundaram; T. Shantha Raju; Nancy L. Shaper; Pamela Stanley

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October 24, 2003

Near adult heights after growth hormone treatment in patients with idiopathic short stature or idiopathic growth hormone deficiency

Journal of Pediatric Endocrinology and Metabolism, ISSN: 0334018X

J. Paul Frindik; Stephen F. Kemp; Joanne Julius Hunold

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October 24, 2003

Diagnostic growth hormone deficiency testing practices among patients in the NCGS/NCSS databases

Journal of Pediatric Endocrinology and Metabolism, ISSN: 0334018X

Richard A. Levy; Connelly

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October 20, 2003

Generic/matrix evaluation of SV40 clearance by anion exchange chromatography in flow-through mode

Biotechnology and Bioengineering, ISSN: 00063592

Sherrie Curtis; Kitty Lee; Gregory S. Blank; Kurt Brorson; Yuan Xu

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October 15, 2003

Cortical and retinal defects caused by dosage-dependent reductions in VEGF-A paracrine signaling

Developmental Biology, ISSN: 00121606

Jody Haigh; Paula I. Morelli; Holger Gerhardt; Katharina Haigh; John Tsien; Annette Damert; Lucile Miquerol; Ulrich Muhlner; Rüdiger Klein; Napoleone Ferrara; Wagner; Christer Betsholtz; Andras Nagy

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October 10, 2003

A neurexin-related protein, BAM-2, terminates axonal branches in C. elegans

Science, ISSN: 00368075

Antonio Colavita; Marc Tessier-Lavigne

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October 8, 2003

Validity and realiability of patient reported outcomes used in psoriasis: Results from two randomized clinical trials

Health and Quality of Life Outcomes, ISSN: 14777525

Richard Shikiar; Bresnahan; Stephen P. Stone; Christine Thompson; John Y. Koo; Dennis A. Revicki

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October 1, 2003

EG-VEGF and Bv8: A novel family of tissue-selective mediators of angiogenesis, endothelial phenotype, and function

Trends in Cardiovascular Medicine, ISSN: 10501738

Jennifer Lecouter; Napoleone Ferrara

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October 1, 2003

Population pharmacokinetics and pharmacodynamics of enoxaparin in unstable angina and non-ST-segment elevation myocardial infarction

British Journal of Clinical Pharmacology, ISSN: 03065251

Rene Bruno; Pascale Baille; Sylvie Retout; Nicole Vivier; Christine Veyrat-Follet; Ger-Jan Sanderink; Richard C. Becker; Elliott M. Antman

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October 1, 2003

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: A bioinformatics assessment

Genome Research, ISSN: 10889051

Hilary F. Clark; Austin L. Gurney; Evangeline Abaya; Kevin Baker; Daryl T. Baldwin; Brush; Jian Chen; Bernard Chow; Clarissa Chui; Crowley; Bridget Currell; Bethanne Deuel; Patrick Dowd; Dan L. Eaton; Foster; Grimaldi; Qimin Gu; Hass; Sherry Heldens; Arthur Huang; Hok Seon Kim; Laura Klimowski; Yisheng Jin; Stephanie Johnson; James Lee; Lhney Lewis; Dong-Zhou Liao; Melanie R Mark; Edward Robbie; Celina Sanchez; Schoenfeld; Somasekar Seshagiri; Laura C. Simmons; Singh; Victoria Smith; Stinson; Alicia Vagts; Richard L. Vandlen; Colin K. Watanabe; David Wieand; Kathryn Woods; Xie; Yansura; Sothy Yi; Guoying Yu; Jean Q. Yuan; Min Zhang; Zemin Zhang; Goddard; William I. Wood; Godowski

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October 1, 2003

Emerging technologies that overcome biological barriers for therapeutic protein delivery

Expert Opinion on Biological Therapy, ISSN: 14712598

Daugherty; Mrsny

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October 1, 2003

Crystal structures of the benzene and ethanol solvates of neotame

Journal of Chemical Crystallography, ISSN: 10741542

Zedong Dong; Victor G. Young Jr.; Eric Munson; Steve A. Schroeder; Indra Prakash; David J. W. Grant

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September 26, 2003

Comprehensive mutagenesis of the C-terminal domain of the M13 gene-3 minor coat protein: The requirements for assembly into the bacteriophage particle

Journal of Molecular Biology, ISSN: 00222836

Gregory A. Weiss; Tomer A. Roth; Pierre F. Baldi; Sachdev S. Sidhu

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September 19, 2003

Tissue expression, protease specificity, and Kunitz domain functions of hepatocyte growth factor activator inhibitor-1B (HAI-1B), a new splice variant of HAI-1

Journal of Biological Chemistry, ISSN: 00219258

Daniel Kirchhofer; Peek; Wei Li; Jennifer Stamos; Eigenbrot; Saloumeh Kadkhodayan; J. Michael Elliott; Corpuz; Lazarus; Paul Moran

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September 19, 2003

Contributions of CDR3 to VHH domain stability and the design of monobody scaffolds for naive antibody libraries

Journal of Molecular Biology, ISSN: 00222836

Christopher J. Bond; James C. Marsters Jr.; Sachdev S. Sidhu

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September 18, 2003

The function role of GATA-3 in Th1 and Th2 differentiation

Immunologic Research, ISSN: 0257277X

Meixia Zhou; Wenjun Ouyang

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September 15, 2003

Plasmin activates the lymphangiogenic growth factors VEGF-C and VEGF-D

Journal of Experimental Medicine, ISSN: 00221007

Bradley K. McColl; Megan E. Baldwin; Sally Roufail; Craig Freeman; Robert L. Moritz; Pichard J. Simpson; Kari Alitalo; Steven A. Stacker; Marc G. Achen

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September 15, 2003

Genome-wide identification of chromosomal regions of increased tumor expression by transcriptome analysis

Cancer Research, ISSN: 00085472

Yan Zhou; Shiuh-Ming Luoh; Yan Zhang; Colin K. Watanabe; Thomas D Wu; Michael Ostland; William I. Wood; Zemin Zhang

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September 12, 2003

Prostaglandin E2 regulates cell migration via the intracellular activation of the epidermal growth factor receptor

Journal of Biological Chemistry, ISSN: 00219258

F. Gregory Buchanan; Dingzhi Wang; Francesca Bargiacchi; Raymond N. DuBois

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September 5, 2003

The functional binding epitope of a high affinity variant of human growth hormone mapped by shotgun alanine-scanning mutagenesis: Insights into the mechanisms responsible for improved affinity

Journal of Molecular Biology, ISSN: 00222836

Gábor Pál; Anthony A. Kossiakoff; Sachdev S. Sidhu

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September 1, 2003

Bacteriophage that display small molecules

Chemistry and Biology, ISSN: 10745521

Frederic A. Fellouse; Deshayes

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September 1, 2003

ABRF-PRG03: Phosphorylation site determination

Journal of Biomolecular Techniques, ISSN: 15240215 19434731

David Arnott; Mary Ann Gawinowicz; Raymond A. Grant; Thomas A. Neubert; Len C. Packman; Kaye D. Speicher; Kathryn Stone; Christoph W. Turck

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September 1, 2003

Superwarfarin and glass ingestion with prolonged coagulopathy requiring high-dose vitamin K1 therapy

Pharmacotherapy, ISSN: 02770008

Ben T. Tsutaoka; Michael Miller; Stacey M. Fung; Manish M. Patel; Kent R. Olson

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September 1, 2003

An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors

Molecular Cell, ISSN: 10972765

Antony W. Burgess; Hyun-Soo Cho; Eigenbrot; Kathryn M. Ferguson; Thomas P.J. Garrett; Daniel J. Leahy; Mark A. Lemmon; Mark X. Sliwkowski; Colin W. Ward; Shigeyuki Yokoyama

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September 1, 2003

Shedding light on bioscience. Symposium on optical imaging: Applications to biology and medicine

EMBO Reports, ISSN: 1469221X

Mary J. Cole; Melinda Pirity; Anna-Katerina Hadjantonakis

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August 26, 2003

Relation between hospital intra-aortic balloon counterpulsation volume and mortality in acute myocardial infarction complicated by cardiogenic shock

Circulation, ISSN: 00097322

Edmond W. Chen; John G. Canto; Lori Parsons; Eric D. Peterson; Katherine A. Littrell; Nathan R. Every; C.Michael Gibson; Judith S. Hochman; E. Magnus Ohman; Morris Cheeks; Hal V. Barron

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August 15, 2003

Photodetachment of hydrated oxalate dianions in the gas phase, C 2O42-(H2O)n (n-3-40): From solvated clusters to nanodroplet

Journal of Chemical Physics, ISSN: 00219606

Xue-Bin Wang; Xin Yang; John B. Nicholas; Lai-Sheng Wang

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August 12, 2003

Complex with a phage display-derived peptide provides insight into the function of insulin-like growth factor I

Biochemistry, ISSN: 00062960

Schaffer; Deshayes; Nakamura; Sachdev S. Sidhu; Nicholas J. Skelton

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August 11, 2003

Dynamics of cell surface molecules during T cell recognition

Annual Review of Biochemistry, ISSN: 00664154

Mark M. Davis; Michelle Krogsgaard; Johannes B. Huppa; Cenk Sumen; Marco A. Purbhoo; Darrell J. Irvine; Lawren C. Wu; Lauren Ehrlich

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August 8, 2003

The forkhead transcription factor FOXO4 induces the down-regulation of hypoxia-inducible factor 1α by a von Hippel-Lindau protein-independent mechanism

Journal of Biological Chemistry, ISSN: 00219258

Tracy Tzu-Ling Tang; Lasky

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August 8, 2003

Structural insight into how an anti-idiotypic antibody against D3H44 (anti-tissue factor antibody) restores normal coagulation

Journal of Molecular Biology, ISSN: 00222836

Eigenbrot; Meng; Rajeswari Krishnamurthy; Michael T. Lipari; Presta; Devaux; Wong; Paul Moran; Sherron L. Bullens; Daniel Kirchhofer

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