Genentech: Publications

May 15, 2002

Predictors of door-to-balloon delay in primary angioplasty

American Journal of Cardiology, ISSN: 00029149

Brad G. Angeja; C.Michael Gibson; Richard Chin; Paul D. Frederick; Nathan R. Every; Ross; Gregg W Stone; Hal V. Barron

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May 10, 2002

A novel type I cytokine receptor is expressed on monocytes, signals proliferation, and activates STAT-3 and STAT-5

Journal of Biological Chemistry, ISSN: 00219258

Nico Ghilardi; Ji Li; Hongo; Sothy Yi; Austin L. Gurney; Frederic J. De Sauvage

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May 10, 2002

ANGPTL3 stimulates endothelial cell adhesion and migration via integrin αvβ3 and induces blood vessel formation in vivo

Journal of Biological Chemistry, ISSN: 00219258

Camenisch; Pisabarro; Sherman; Joe Kowalski; Mark Nagel; Hass; Xie; Austin L. Gurney; Bodary; Xiao Huan Liang; Clark; Beresini; Napoleone Ferrara; Hans-Peter Gerber

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May 1, 2002

Expression of full-length immunoglobulins in Escherichia coli: Rapid and efficient production of aglycosylated antibodies

Journal of Immunological Methods, ISSN: 00221759

Laura C. Simmons; Dorothea Reilly; Laura Klimowski; T. Shantha Raju; Meng; Paul Sims; Kyu Hong; Robert L. Shields; Lisa A. Damico; Rancatore; Yansura

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May 1, 2002

Psoriasis as a model for T-cell-mediated disease: Immunobiologic and clinical effects of treatment with multiple doses of efalizumab, an anti-CD11a antibody

Archives of Dermatology, ISSN: 0003987X

Alice Gottlieb; James G. Krueger; Knut Wittkowski; Russell L Dedrick; Patricia Walicke; Marvin Garovoy

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May 1, 2002

Prostate stem cell antigen as therapy target: Tissue expression and in vivo efficacy of an immunoconjugate

Cancer Research, ISSN: 00085472

Ross; Spencer; Ilona N. Holcomb; Christine Tan; Hongo; Devaux; Linda Rangell; Gilbert-Andre Keller; Peter Schow; Rita M. Steeves; Robert J. Lutz; Gretchen D. Frantz; Kenneth J. Hillan; Franklin V. Peale Jr.; Tobin; Eberhard; Mark A. Rubin; Lasky; Koeppen

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May 1, 2002

Anti-adhesion antibodies Efalizumab, a humanized anti-CD11a monoclonal antibody

Transplant Immunology, ISSN: 09663274

Russell L Dedrick; Patricia Walicke; Marvin Garovoy

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April 19, 2002

Synergistic induction of tumor antigens by Wnt-1 signaling and retinoic acid revealed by gene expression profiling

Journal of Biological Chemistry, ISSN: 00219258

David A. Tice; Szeto; Soloviev; Bonnee Rubinfeld; Fong; Dugger; Jane Winer; Mickey Williams; David Wieand; Victoria Smith; Ralph H. Schwall; Diane Pennica; Paul G. Polakis

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April 19, 2002

Increases in free, unbound insulin-like growth factor I enhance insulin responsiveness in human hepatoma G2 cells in culture

Journal of Biological Chemistry, ISSN: 00219258

Keiji Sakai; Henry B. Lowman; David R. Clemmons

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April 19, 2002

The forkhead transcription factor AFX activates apoptosis by induction of the BCL-6 transcriptional repressor

Journal of Biological Chemistry, ISSN: 00219258

Tracy Tzu-Ling Tang; Dowbenko; Amanda Jackson; Lisa Toney; Lewin; Alexander Dent; Lasky

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April 15, 2002

Fusion of two distinct peptide exosite inhibitors of Factor VIIa

Biochemical Journal, ISSN: 02646021

Roberge; Peek; Daniel Kirchhofer; Dennis; Lazarus

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April 15, 2002

On the variability of covariate adjustment: Experience with Koch's method for evaluating the absolute difference in proportions in randomized clinical trials

Controlled Clinical Trials, ISSN: 01972456

Emmanuel Lesaffre; Kris Bogaerts; Xin Li; Bluhmki

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April 12, 2002

The Erbin PDZ domain binds with high affinity and specificity to the carboxyl termini of δ-catenin and ARVCF

Journal of Biological Chemistry, ISSN: 00219258

Richard Laura; Andrea S. Witt; Heike A. Held; Gerstner; Deshayes; Michael F. T. Koehler; Kenneth S. Kosik; Sachdev S. Sidhu; Lasky

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April 9, 2002

Lavage and nipple aspiration of breast ductal fluids: A source of biomarkers for environmental mutagenesis

Environmental and Molecular Mutagenesis, ISSN: 08936692

Pam Klein; Julia A. Lawrence

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April 9, 2002

Cardiotrophin-1 (CT-1) can protect the adult heart from injury when added both prior to ischaemia and at reperfusion

Cardiovascular Research, ISSN: 00086363

Zhihong Liao; Bhawanjit K. Brar; Qing Cai; Anastatis Stephanou; O'Leary; Diane Pennica; Derek M Yellon; David S. Latchman

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April 6, 2002

Exaggerated hypotensive effect of vascular endothelial growth factor in spontaneously hypertensive rats

Hypertension, ISSN: 0194911X

Renhui Yang; Annie Ogasawara; Zioncheck; Zhen Ren; Guo-Wei He; Geralyn G. Deguzman; Nicolas Pelletier; Shen; Bunting; Hongkui Jin

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April 5, 2002

SMAC negatively regulates the anti-apoptotic activity of melanoma inhibitor of apoptosis (ML-IAP)

Journal of Biological Chemistry, ISSN: 00219258

Domagoj Vucic; Deshayes; Heidi J. A. Wallweber; Pisabarro; Saloumeh Kadkhodayan; Wayne J. Fairbrother; Vishva M. Dixit

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April 5, 2002

A dominant-negative p65 PAK peptide inhibits angiogenesis

Circulation Research, ISSN: 00097330

William B. Kiosses; John Hood; Suya Yang; Mary E. Gerritsen; David A. Cheresh; Nazilla Alderson; Martin Alexander Schwartz

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April 3, 2002

Biotransformation reactions of five-membered aromatic heterocyclic rings

Chemical Research in Toxicology, ISSN: 0893228X

Deepak Dalvie; Amit S. Kalgutkar; S. Cyrus Khojasteh; R. Scott Obach; John O'Donnell

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April 1, 2002

Recombinant protein expression for therapeutic applications

Current Opinion in Biotechnology, ISSN: 09581669

Dana C. Andersen; Lynne Krummen

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March 31, 2002

Progress in understanding the structure-activity relationships of P-glycoprotein

Advanced Drug Delivery Reviews, ISSN: 0169409X

Terry R Stouch; Gudmundsson

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March 29, 2002

AKT/PKB phosphorylation of p21Cip/WAF1 enhances protein stability of p21Cip/WAF1 and promotes cell survival

Journal of Biological Chemistry, ISSN: 00219258

Ying Li; Dowbenko; Lasky

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March 25, 2002

A human antibody that inhibits factor IX/IXa function potently inhibits arterial thrombosis without increasing bleeding

Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN: 10795642

Refino; Surinc Er Jeet; Leo Deguzman; Bunting; Daniel Kirchhofer

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March 25, 2002

Inhibitors of protein-protein interactions

Expert Opinion on Therapeutic Patents, ISSN: 13543776

Denise A. Ockey; Thomas Gadek

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March 15, 2002

Identification of a novel homotypic interaction motif required for the phosphorylation of receptor-interacting protein (RIP) by RIP3

Journal of Biological Chemistry, ISSN: 00219258

Xiaoqing Sun; Jianping Yin; Melissa A. Starovasnik; Wayne J. Fairbrother; Vishva M. Dixit

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March 8, 2002

Characterization of endocrine gland-derived vascular endothelial growth factor signaling in adrenal cortex capillary endothelial cells

Journal of Biological Chemistry, ISSN: 00219258

Rui Lin; Jennifer Lecouter; Joe Kowalski; Napoleone Ferrara

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March 7, 2002

1H, 13C, and 15N resonance assignment of the vascular endothelial growth factor receptor-binding domain in complex with a receptor-blocking peptide [5]

Journal of Biomolecular NMR, ISSN: 09252738

Borlan Pan; Wayne J. Fairbrother

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March 7, 2002

Methylbenzene chemistry on zeolite HBeta: Multiple insights into methanol-to-olefin catalysis

Journal of Physical Chemistry B, ISSN: 10895647

Alain Sassi; Mark A. Wildman; Hee Jung Ahn; Paritosh Prasad; John B. Nicholas; James F. Haw

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March 5, 2002

Chemometric evaluation of on-line high-pressure liquid chromatography in mammalian cell cultures: Analysis of amino acids and glucose

Biotechnology and Bioengineering, ISSN: 00063592

Tina M. Larson; Martin Gawlitzek; Heather Evans; Urs Albers; Cacia

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March 5, 2002

Expression profiling of a human cell line model of prostatic cancer reveals a direct involvement of interferon signaling in prostate tumor progression

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Shou; Robert Soriano; Simon W. Hayward; Gerald R. Cunha; P. Mickey Williams; Gao

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March 1, 2002

Cardiac dysfunction in the trastuzumab clinical trials experience

Journal of Clinical Oncology, ISSN: 0732183X

Andrew Seidman; Clifford Hudis; Mary Kathryn Pierri; Steven Shak; Virginia Paton; Ashby; Maureen Murphy; Stanford J. Stewart; Deborah Keefe

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March 1, 2002

Microcirculation down under

Trends in Pharmacological Sciences, ISSN: 01656147

Tailoi Chan-Ling; Mary E. Gerritsen; Caryl E Hill; Paul Kubes; Michael Perry

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February 22, 2002

Activation of the Wnt pathway interferes with serum response element-driven transcription of immediate early genes

Journal of Biological Chemistry, ISSN: 00219258

David A. Tice; Soloviev; Paul G. Polakis

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February 15, 2002

The core membrane fusion complex governs the probability of synaptic vesicle fusion but not transmitter release kinetics

Journal of Neuroscience, ISSN: 02706474

Finley; Sejal M. Patel; Daniel V. Madison; Richard H. Scheller

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February 15, 2002

Vascular endothelial-junctional adhesion molecule (VE-JAM)/JAM 2 interacts with T, NK, and dendritic cells through JAM 3

Journal of Immunology, ISSN: 00221767

Tony W. Liang; Chiu; Austin L. Gurney; Aiko Sidle; Daniel B. Tumas; Peter Schow; Foster; Toni Klassen; Kathryn Dennis; Richard A. Demarco; Thinh Q. Pham; Gretchen D. Frantz; Sherman Fong

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February 15, 2002

Bacterial toxins as tools for mucosal vaccination

Drug Discovery Today, ISSN: 13596446

Mrsny; Daugherty; Marian McKee; David FitzGerald

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February 15, 2002

Vascular endothelial-junctional adhesion molecule (VE-JAM)/JAM 2 interacts with T, NK, and dendritic cells through JAM 3

Journal of Immunology, ISSN: 00221767

Tony W. Liang; Chiu; Austin L. Gurney; Aiko Sidle; Daniel B. Tumas; Peter Schow; Foster; Toni Klassen; Kathryn Dennis; Richard A. Demarco; Thinh Q. Pham; Gretchen D. Frantz; Fong

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February 11, 2002

Cold elicits the simultaneous induction of fatty acid synthesis and β-oxidation in murine brown adipose tissue: Prediction from differential gene expression and confirmation in vivo

FASEB Journal, ISSN: 08926638

Xing Xian; Lewin; William F. Forrest; Adams

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February 8, 2002

Generation of an LFA-1 antagonist by the transfer of the ICAM-1 immunoregulatory epitope to a small molecule

Science, ISSN: 00368075

Thomas Gadek; Burdick; Robert S. McDowell; Mark S. Stanley; James C. Marsters Jr.; Kenneth J. Paris; David A. Oare; Mark E. Reynolds; Ladner; Kimberly Zioncheck; Wyne P. Lee; Gribling; Dennis; Nicholas J. Skelton; Daniel B. Tumas; Clark; Keating; Beresini; Tilley; Presta; Bodary

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February 5, 2002

Stable "zeta" peptides that act as potent antagonists of the high-affinity IgE receptor

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Nakamura; Mark E. Reynolds; Chen; Melissa A. Starovasnik; Henry B. Lowman

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February 5, 2002

Surface-tension-confined microfluidics

Langmuir, ISSN: 07437463

Philippe Lam; Kenneth J. Wynne; Gary E. Wnek

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February 5, 2002