Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 11051 - 11100 OF 15217 RESULTS

Analysis of Smoothened as a candidate gene for human holoprosencephaly
Gene Function and Disease, ISSN: 14387506
Jeffrey E. Ming; Bennie Jeng; Frederic J. De Sauvage; Maximilian Muenke
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Quantifying β-sheet stability by phage display
Journal of Molecular Biology, ISSN: 00222836
Mark D. Distefano; Zhong; Andrea G Cochran
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Role of vascular endothelial growth factor in physiologic and pathologic angiogenesis: therapeutic implications.
Seminars in Oncology, ISSN: 00937754
Napoleone Ferrara
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The product development continuum: the evolution and application of the concept of comparability.
Developments in Biologicals, ISSN: 14246074
Robert L. Garnick
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Detection of minute virus of mice using real time quantitative PCR in assessment of virus clearance during the purification of mammalian cell substrate derived biotherapeutics
Biologicals, ISSN: 10451056
Dejin Zhan; Margaret Roy; Christine Valera; Jesse Cardenas; Vennari; Janice W. Chen; Shengjiang Liu
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Challenges with current technology for the detection, measurement and characterization of antibodies against biological therapeutics.
Developments in Biologicals, ISSN: 14246074
Mire-Sluis
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Regulation of Apo2L/tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in thyroid carcinoma cells
American Journal of Pathology, ISSN: 00029440
Vassiliki Poulaki; Constantine S. Mitsiades; Vassiliki Kotoula; Sophia Tseleni-Balafouta; Avi Ashkenazi; Demetrios A. Koutras; Nicholas Mitsiades
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From characterization of antibodies to prediction of immunogenicity.
Developments in Biologicals, ISSN: 14246074
Koren
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In vivo regulation of plasminogen function by plasma carboxypeptidase B
Journal of Clinical Investigation, ISSN: 00219738
Carmen M. Swaisgood; Schmitt; Dan L. Eaton; Edward F. Plow
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A minimized M13 coat protein defines the requirements for assembly into the bacteriophage particle
Journal of Molecular Biology, ISSN: 00222836
Tomer A. Roth; Gregory A. Weiss; Eigenbrot; Sachdev S. Sidhu
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Sequence plasticity in the antigen-binding site of a therapeutic anti-Her2 antibody
Journal of Molecular Biology, ISSN: 00222836
Gerstner; Paul J. Carter; Henry B. Lowman
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MAGI-1: A widely expressed, alternatively spliced tight junction protein
Experimental Cell Research, ISSN: 00144827
Richard Laura; Ross; Koeppen; Lasky
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Cardiotrophin-1 and urocortin cause protection by the same pathway and hypertrophy via distinct pathways in cardiac myocytes
Cytokine, ISSN: 10434666
Julia Railson; Zhihong Liao; Bhawanjit K. Brar; Joanna C. Buddle; Diane Pennica; Anastatis Stephanou; David S. Latchman
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Development of a frozen cell array as a high-throughput approach for cell-based analysis
American Journal of Pathology, ISSN: 00029440
Jean-Philippe Stephan; Silvia Schanz; Anne Wong; Peter Schow; Wai Lee T. Wong
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Inhospital outcome of acute myocardial infarction in patients with prior coronary artery bypass surgery
American Heart Journal, ISSN: 00028703
Verghese Mathew; Bernard Gersh; Hal V. Barron; Nathan R. Every; Alan J. Tiefenbrunn; Paul D. Frederick; Judith A. Malmgren
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A slow release formulation of insulin as a treatment for osteoarthritis
Osteoarthritis and Cartilage, ISSN: 10634584
Liping Cai; Okumu; Cleland; Beresini; Deborah A. Hogue; Lin; Ellen H. Filvaroff
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Measuring patients' trust in their primary care providers
Medical Care Research and Review, ISSN: 10775587
Mark A. Hall; Zheng; Elizabeth Dugan; Fabian Camacho; Kristin E. Kidd; Aneil Mishra; Rajesh Balkrishnan
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Can a small-molecular gadolinium contrast agent be applied successfully with dynamic MRI to quantitatively define brain tumor microvascular responses to angiogenesis inhibition?
Academic Radiology, ISSN: 10766332
Robert C. Brasch; Axel Gossmann; Thomas H. Helbich; Nagato Kuriyama; Timothy P.L. Roberts; David M. Shames; Nicholas Van Bruggen; Michael F. Wendland; Mark A. Israel
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Effects of early treatment with growth hormone on infarct size, survival, and cardiac gene expression after acute myocardial infarction
Growth Hormone and IGF Research, ISSN: 10966374
Hongkui Jin; Renhui Yang; Hsienwie Lu; Annie Ogasawara; Wei Li; Anne Ryan; Franklin V. Peale Jr.; Nicholas F. Paoni
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Epigenetic changes in tumor Fas levels determine immune escape and response to therapy
Cancer Cell, ISSN: 15356108
Heather Maecker; Zhong Yun; Holden T. Maecker; Amato J. Giaccia
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Expression of transgene encoded TGF-β in islets prevents autoimmune diabetes in NOD mice by a local mechanism
Journal of Autoimmunity, ISSN: 08968411
Iqbal S. Grewal; Kate D. Grewal; F. Susan Wong; Hua Wang; Dominic E. Picarella; Charles A. Janeway Jr.; Richard A. Flavell
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Solution structure of a phage-derived peptide antagonist in complex with vascular endothelial growth factor
Journal of Molecular Biology, ISSN: 00222836
Borlan Pan; Bing Li; Russell; Jeffrey Tom; Andrea G Cochran; Wayne J. Fairbrother
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Amino acid determinants of β-hairpin conformation in erythropoeitin receptor agonist peptides derived from a phage display library
Journal of Molecular Biology, ISSN: 00222836
Nicholas J. Skelton; Russell; Frederic J. De Sauvage; Andrea G Cochran
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Structure of a phage display-derived variant of human growth hormone complexed to two copies of the extracellular domain of its receptor: Evidence for strong structural coupling between receptor binding sites
Journal of Molecular Biology, ISSN: 00222836
Celia A. Schiffer; Ultsch; Scott Walsh; Somers; De Vos; Anthony A. Kossiakoff
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Comprehensive functional maps of the antigen-binding site of an anti-ErbB2 antibody obtained with shotgun scanning mutagenesis
Journal of Molecular Biology, ISSN: 00222836
Vajdos; Adams; Timothy N. Breece; Presta; De Vos; Sachdev S. Sidhu
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A mouse model of hepatocellular carcinoma: Ectopic expression of fibroblast growth factor 19 in skeletal muscle of transgenic mice
American Journal of Pathology, ISSN: 00029440
Nicholes; Guillet; Elizabeth Tomlinson; Kenneth J. Hillan; Wright; Gretchen D. Frantz; Thinh Q. Pham; Lisa Dillard-Telm; Siao Ping Tsai; Jean-Philippe Stephan; Stinson; Stewart; French
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VEGF regulates remodeling during permanent anatomic closure of the ductus arteriosus
American Journal of Physiology - Regulatory Integrative and Comparative Physiology, ISSN: 03636119
Ronald I. Clyman; Steven R. Seidner; Hiroki Kajino; Christine Roman; Cameron J. Koch; Napoleone Ferrara; Nahid Waleh; Françoise Mauray; Yao Qi Chen; Elizabeth A. Perkett; Timothy Quinn
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Increased expression of cardiotrophin-1 during ventricular remodeling in hypertensive rats
American Journal of Physiology - Heart and Circulatory Physiology, ISSN: 03636135
Yoshihito Takimoto; Takeshi Aoyama; Yoshitaka Iwanaga; Toshiaki Izumi; Yasuki Kihara; Diane Pennica; Shigetake Sasayama
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Semisolid, self-catalyzed poly(ortho ester)s as controlled-release systems: Protein release and protein stability issues
Journal of Pharmaceutical Sciences, ISSN: 00223549
Marco De Van Weert; Marinus J. Van Steenbergen; Cleland; Jorge Heller; Wim E. Hennink; Daan J. A. Crommelin
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Surface adsorption of recombinant human interferon-γ in lyophilized and spray-lyophilized formulations
Journal of Pharmaceutical Sciences, ISSN: 00223549
Serena D. Webb; Stephen L. Golledge; Cleland; John F. Carpenter; Theodore W. Randolph
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Selected topics in parallel line bioassay.
Developments in Biologicals, ISSN: 14246074
Giltinan
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Characterization and implications of bioassay variation.
Developments in Biologicals, ISSN: 14246074
Michael Ostland
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Vesicle budding from endoplasmic reticulum
Methods in Enzymology, ISSN: 00766879
Yuval Shimoni; Randy Schekman
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Targeting death and decoy receptors of the tumour-necrosis factor superfamily
Nature Reviews Cancer, ISSN: 1474175X
Avi Ashkenazi
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Transgenic mice expressing human fibroblast growth factor-19 display increased metabolic rate and decreased adiposity
Endocrinology, ISSN: 00137227
Elizabeth Tomlinson; Ling Fu; Linu M. John; Hultgren; Huang; Renz; Jean-Philippe Stephan; Siao Ping Tsai; Powell-Braxton; French; Stewart
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Pharmacokinetics of rhuMAb CD18, a recombinant humanised monoclonal antibody fragment to CD18, in normal healthy human volunteers
BioDrugs, ISSN: 11738804
David E. Allison; Steven G. Gourlay; Koren; Miller; Judy Fox
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Prevention of experimental choroidal neovascularization with intravitreal anti-vascular endothelial growth factor antibody fragment
Archives of Ophthalmology, ISSN: 00039950
Magdalena G. Krzystolik; Mehran A. Afshari; Anthony P. Adamis; Jacques Gaudreault; Evangelos S. Gragoudas; Norman Michaud; Wenjun Li; Edward Connolly; Charles A. O'Neill; Joan W. Miller
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Effect of growth hormone therapy on height in children with idiopathic short stature: A meta-analysis
Archives of Pediatrics and Adolescent Medicine, ISSN: 10724710
Beth S. Finkelstein; Thomas F. Imperiale; Theodore Speroff; Ursula Marrero; Deborah J. Radcliffe; Leona Cuttler
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Dynamic contrast-enhanced magnetic resonance imaging as a surrogate marker of tumor response to anti-angiogenic therapy in a xenograft model of glioblastoma multiforme
Journal of Magnetic Resonance Imaging, ISSN: 10531807
Axel Gossmann; Thomas H. Helbich; Nagato Kuriyama; Ostrowitzki; Timothy P.L. Roberts; David M. Shames; Nicholas Van Bruggen; Michael F. Wendland; Mark A. Israel; Robert C. Brasch
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The association of sex and payer status on management and subsequent survival in acute myocardial infarction
Archives of Internal Medicine, ISSN: 00039926
John G. Canto; William J. Rogers; Nisha C. Chandra; William J. French; Hal V. Barron; Paul D. Frederick; Charles Maynard|; Nathan R. Every
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Rituximab in combination with CHOP or fludarabine in low-grade lymphoma
Seminars in Oncology, ISSN: 00937754
Myron S. Czuczman; Alexandra Fallon; Mohr; Stewart; Bernstein; McCarthy; Skipper; Brown; Kena Miller; Diane Wentling; Klippenstein; Loud; Mike K Rock; Benyunes; Grillo-Lopez; Bernstein
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Identification of a novel death domain-containing adaptor molecule for ectodysplasin-A receptor that is mutated in crinkled mice
Current Biology, ISSN: 09609822
Minhong Yan; Zemin Zhang; John B.B. Ridgway; Sarah Schilbach; Wayne J. Fairbrother; Vishva M. Dixit
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VEGF-A has a critical, nonredundant role in angiogenic switching and pancreatic β cell carcinogenesis
Cancer Cell, ISSN: 15356108
Masahiro Inoue; Jeffrey H. Hager; Napoleone Ferrara; Hans-Peter Gerber; Douglas Hanahan
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Large-scale analysis of gene expression profiles.
Briefings in bioinformatics, ISSN: 14675463
Thomas D Wu
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Acute ischemic syndromes: Adjunctive therapy
Cardiology Clinics, ISSN: 07338651
Katherine A. Littrell; Karl B. Kern
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Selective detection of membrane proteins without antibodies: a mass spectrometric version of the Western blot.
Molecular and Cellular Proteomics, ISSN: 15359476
David Arnott; Kishiyama; Luis; Sarah Ludlum; James C. Marsters Jr.; Stults
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Evaluation of a quantitative product-enhanced reverse transcriptase assay to monitor retrovirus in mAb cell-culture
Biologicals, ISSN: 10451056
Kurt Brorson; Yuan Xu; Patrick Swann; Elizabeth Hamilton; Mehnaz Mustafa; Christina De Wit; Lenore A Norling; Kathryn Stein
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A real-time quantitative PCR-based method for the detection and quantification of xenotropic Murine Leukemia Virus (X-MuLV) and its application in evaluation of X-MuLV removal during pharmaceutical protein purification
Process in Safety Science and Technology Part B,
Shi; Qi Chen; Lenore A Norling; Allen S.L. Lau; Sherrie Krejci; Yuan Xu
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Hippocampal dysfunction and behavioral deficit in the water maze in mice: An unresolved issue?
Brain Research Bulletin, ISSN: 03619230
Gerlai; Alexander McNamara; Simon P. Williams; Phillips
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The importance of freezing on lyophilization cycle development
BioPharm, ISSN: 10408304
Thomas W. Patapoff; David E. Overcashier
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