Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 11201 - 11250 OF 15217 RESULTS

Selection and characterization of a new class of peptide exosite inhibitors of coagulation factor VIIa
Biochemistry, ISSN: 00062960
Dennis; Roberge; Quan; Lazarus
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The factor VII zymogen structure reveals reregistration of β strands during activation
Structure, ISSN: 09692126
Eigenbrot; Daniel Kirchhofer; Dennis; Santell; Lazarus; Jennifer Stamos; Ultsch
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Cardiotrophin-1 can protect cardiac myocytes from injury when added both prior to simulated ischaemia and at reoxygenation
Cardiovascular Research, ISSN: 00086363
Bhawanjit K. Brar; Anastatis Stephanou; Zhihong Liao; O'Leary; Diane Pennica; Derek M Yellon; David S. Latchman
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TACI-ligand interactions are required for T cell activation and collagen-induced arthritis in mice
Nature Immunology, ISSN: 15292908
Hua Wang; Scot A. Marsters; Thad Baker; Betty Chan; Wyne P. Lee; Ling Fu; Daniel B. Tumas; Minhong Yan; Vishva M. Dixit; Avi Ashkenazi; Iqbal S. Grewal
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Activation and accumulation of B cells in TACI-deficient mice
Nature Immunology, ISSN: 15292908
Minhong Yan; Hua Wang; Betty Chan; Merone Roose-Girma; Sharon Erickson; Thad Baker; Daniel B. Tumas; Iqbal S. Grewal; Vishva M. Dixit
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αvβ3 antagonists based on a central thiophene scaffold
Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X
Peyman; Karl-Heinz Scheunemann; Will; Knolle; Volkmar Wehner; Breipohl; Stilz; Denis Carniato; Ruxer; Gourvest; Auberval; Doucet; Roland Baron; Gaillard; Thomas Gadek; Bodary
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Mapping protein-protein interactions with combinatorial biology methods
Current Opinion in Biotechnology, ISSN: 09581669
Joelle Pelletier; Sachdev S. Sidhu
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Physiological modulation of rabphilin phosphorylation
Journal of Neuroscience, ISSN: 02706474
Davide Foletti; Jeremy T. Blitzer; Richard H. Scheller
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Developmental regulation and specific brain distribution of phosphorabphilin
Journal of Neuroscience, ISSN: 02706474
Davide Foletti; Richard H. Scheller
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A glucose-responsive transcription factor that regulates carbohydrate metabolism in the liver
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Hiromi Yamashita; Makoto Takenoshita; Masaharu Sakurai; Richard K. Bruick; William J. Henzel; Wendy Shillinglaw; David Arnot; Kosaku Uyeda
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Dose schedule of recombinant murine thrombopoietin prior to myelosuppressive and myeloablative therapy in mice
Cancer Chemotherapy and Pharmacology, ISSN: 03445704
Stefanich; Carlson-Zermeno; McEvoy; Mike Reich; Fielder
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Glycoengineering of therapeutic glycoproteins: In vitro galactosylation and sialylation of glycoproteins with terminal N-acetylglucosamine and galactose residues
Biochemistry, ISSN: 00062960
T. Shantha Raju; Briggs; Steven M. Chamow; Winkler; Andrew J.S. Jones
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A Discontinuous SNAP-25 C-terminal Coil Supports Exocytosis
Journal of Biological Chemistry, ISSN: 00219258
Yu A. Chen; Suzie J. Scales; Jagath R. Junutula; Richard H. Scheller
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Three SNARE complexes cooperate to mediate membrane fusion
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Yuanyuan Hua; Richard H. Scheller
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Structure - Function analysis of a phage display-derived peptide that binds to insulin-like growth factor binding protein 1
Biochemistry, ISSN: 00062960
Nicholas J. Skelton; Chen; Dubree; Quan; Jackson; Andrea G Cochran; Zobel; Deshayes; Baca; Pisabarro; Henry B. Lowman
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The general concepts of an equivalence trial, applied to ASSENT-2, a large-scale mortality study comparing two fibrinolytic agents in acute myocardial infarction
European Heart Journal, ISSN: 0195668X
Emmanuel Lesaffre; Bluhmki; Wang-Clow; Berioli; Danays; Fox; Frans Van De Werf
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Physical and functional interactions between Drosophila TRAF2 and Pelle kinase contribute to Dorsal activation
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Baohe Shen; Liu; Edward Y. Skolnik; James L. Manley
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Wrch-1, a novel member of the Rho gene family that is regulated by Wnt-1
Genes and Development, ISSN: 08909369
Weikang Tao; Diane Pennica; Lifeng Xu; Robert F. Kalejta; Arnold J. Levine
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Calcium Regulation of Exocytosis in PC12 Cells
Journal of Biological Chemistry, ISSN: 00219258
Yu A. Chen; Suzie J. Scales; Vikas Duvvuri; Mala Murthy; Sejal M. Patel; Howard Schulman; Richard H. Scheller
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Signaling Pathways Leading to Transcription and Translation Cooperatively Regulate the Transient Increase in Expression of c-Fos Protein
Journal of Biological Chemistry, ISSN: 00219258
Kenji Takeuchi; Sayumi Shibamoto; Kentaro Nagamine; Ichiro Shigemori; Satoshi Omura; Naomi Kitamura; Fumiaki Ito
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Mass spectrometry innovations in drug discovery and development
Pharmaceutical Research, ISSN: 07248741
Damon I. Papac; Shahrokh
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Surface properties, fibrinogen adsorption, and cellular interactions of a novel phosphorylcholine-containing self-assembled monolayer on gold
Langmuir, ISSN: 07437463
Vassiliki A. Tegoulia; Weisun Rao; Anand T. Kalambur; John F. Rabolt; Stuart L. Cooper
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Solvent migration in a paraffin deposit
Fuel, ISSN: 00162361
Cordoba; Schall
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Application of a heat transfer method to determine wax deposition in a hydrocarbon binary mixture
Fuel, ISSN: 00162361
Cordoba; Schall
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Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling
Nature Genetics, ISSN: 10614036
Kui Lin; Honor Hsin; Natasha Libina; Cynthia Kenyon
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Partial molar volume, surface area, and hydration changes for equilibrium unfolding and formation of aggregation transition state: High-pressure and cosolute studies on recombinant human IFN-γ
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Jonathan N. Webb; Serena D. Webb; Cleland; John F. Carpenter; Theodore W. Randolph
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Recognition of 16S rRNA by ribosomal protein S4 from Bacillus stearothermophilus
Biochemistry, ISSN: 00062960
Gerstner; Pak; Draper
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PTEN 2, a Golgi-associated Testis-specific Homologue of the PTEN Tumor Suppressor Lipid Phosphatase
Journal of Biological Chemistry, ISSN: 00219258
Yan Wu; Dowbenko; Pisabarro; Lisa Dillard-Telm; Koeppen; Lasky
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Effects of cardiotrophin-1 (CT-1) in a mouse motor neuron disease
Muscle and Nerve, ISSN: 0148639X
Hiroshi Mitsumoto; Bogdan Klinkosz; Erik P. Pioro; Kazufumi Tsuzaka; Takeo Ishiyama; O'Leary; Diane Pennica
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Early initiation of growth hormone treatment allows age-appropriate estrogen use in Turner's syndrome
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X
Edward O. Reiter; Sandra L. Blethen; Joyce Baptista; Lisa Price
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More than one way to skin a catenin
Cell, ISSN: 00928674
Paul G. Polakis
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A naturally occurring secreted human ErbB3 receptor isoform inhibits heregulin-stimulated activation of ErbB2, ErbB3, and ErbB4
Cancer Research, ISSN: 00085472
Hakjoo Lee; Robert W. Akita; Mark X. Sliwkowski; Nita J. Maihle
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Stimulus properties of 7-OH-DPAT versus auto- and postsynaptic receptor-specific doses of quinpirole
Pharmacology Biochemistry and Behavior, ISSN: 00913057
Christina L. Zuch; Deborah A. Cory-Slechta
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A persistent carbenium ion on the methanol-to-olefin catalyst HSAPO-34: Acetone shows the way
Journal of Physical Chemistry B, ISSN: 10895647
Weiguo Song; John B. Nicholas; James F. Haw
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Lysophosphatidic acid induction of vascular endothelial growth factor expression in human ovarian cancer cells
Journal of the National Cancer Institute, ISSN: 00278874
Yu-Long Hu; Meng-Kian Tee; Edward J. Goetzl; Nelly Auersperg; Gordon B. Mills; Napoleone Ferrara; Robert B. Jaffe
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Overexpression of the retinoic acid-responsive gene Stra6 in human cancers and its synergistic induction by Wnt-1 and retinoic acid
Cancer Research, ISSN: 00085472
Szeto; Wen Jiang; David A. Tice; Bonnee Rubinfeld; Hollingshead; Fong; Dugger; Thinh Q. Pham; Yansura; Wong; J. Christopher Grimaldi; Corpuz; Singh; Gretchen D. Frantz; Devaux; Crowley; Ralph H. Schwall; Eberhard; Rastelli; Paul G. Polakis; Diane Pennica
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Development of poly-(D,L-lactide-coglycolide) microsphere formulations containing recombinant human vascular endothelial growth factor to promote local angiogenesis
Journal of Controlled Release, ISSN: 01683659
Cleland; Duenas; Ann Park; Daugherty; Jeanne Kahn; Joe Kowalski; R. Andrew Cuthbertson
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Tryptophan zippers: Stable, monomeric β-hairpins
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Andrea G Cochran; Nicholas J. Skelton; Melissa A. Starovasnik
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A cardiac myocyte vascular endothelial growth factor paracrine pathway is required to maintain cardiac function
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Frank J. Giordano; Hans-Peter Gerber; Simon P. Williams; Nicholas Vanbruggen; Bunting; Pilar Ruiz-Lozano; Yusu Gu; Anjali K. Nath; Yan Huang; Reed Hickey; Nancy Dalton; Kirk L. Peterson; John Ross Jr.; Kenneth R. Chien; Napoleone Ferrara
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Therapy for 6.5-7.5 years with recombinant insulin-like growth factor I in children with growth hormone insensitivity syndrome: A clinical research center study
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X
Philippe F. Backeljauw; Louis E. Underwood; Miras; Arriazu; Heinrich; Ghizzoni; Sandra L. Blethen; Donaldson; Cleveland; Duncan
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fucosyltransferase1 and H-type complex carbohydrates modulate epithelial cell proliferation during prostatic branching morphogenesis
Developmental Biology, ISSN: 00121606
Paul C. Marker; Jean-Philippe Stephan; James Lee; Bald; Mather; Gerald R. Cunha
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CrkL is an adapter for Wiskott-Aldrich syndrome protein and Syk
Blood, ISSN: 00064971
Atsushi Oda; Hans D. Ochs; Lasky; Spencer; Katsutoshi Ozaki; Mitsuhiro Fujihara; Makoto Handa; Kenji Ikebuchi; Hisami Ikeda
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Chinese hamster ovary (CHO) cells may express six β 4-galactosyltransferases (β4GalTs). Consequences of the loss of functional β4Galt-1, β4GalT-6, or both in CHO glycosylation mutants
Journal of Biological Chemistry, ISSN: 00219258
JaeHoon Lee; Subha Sundaram; Nancy L. Shaper; T. Shantha Raju; Pamela Stanley
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Standard errors for the cox proportional hazards cure model
Mathematical and Computer Modelling, ISSN: 08957177
Sy; Jeremy M.G. Taylor
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Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions [2]
Nature Medicine, ISSN: 10788956
David Lawrence; Shahrokh; Scot A. Marsters; Kirsten Achilles Poon; Danny Shih; Barbara Mounho; Kenneth J. Hillan; Klara Totpal; Laura DeForge; Peter Schow; Jeff Hooley; Steve Sherwood; Roger Pai; Susan Leung; Lolo Khan; Brian Gliniak; Bussiere; Craig A. Smith; Stephen S. Strom; Kelley; Judy Fox; Deborah Thomas; Avi Ashkenazi
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Isotype-dependent inhibition of tumor growth in vivo by monoclonal antibodies to death receptor 4
Journal of Immunology, ISSN: 00221767
Anan Chuntharapai; Dodge; Grimmer; Kurt A. Schroeder; Scot A. Marsters; Koeppen; Avi Ashkenazi; K.Jin Kim
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Rapid method for monitoring galactosylation levels during recombinant antibody production by electrospray mass spectrometry with selective-ion monitoring
Journal of Chromatography A, ISSN: 00219673
Hong Z. Wan; Stacey Kaneshiro; John Frenz; Cacia
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Capillary electrophoresis in the development of recombinant protein biopharmaceuticals
Chromatographia, ISSN: 00095893
Chen; Eleanor Canova-Davis; Anthony B. Chen; Wassim Nashabeh; Timothy Wehr
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Effects of the solution environment on the resolution of recombinant human deoxyribonuclease variants in capillary zone electrophoresis
Chromatographia, ISSN: 00095893
Quan; Eleanor Canova-Davis; Chen; Anthony B. Chen; Wassim Nashabeh; Timothy Wehr
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Capillary electrophoresis in the development of recombinant protein biopharmaceuticals
Chromatographia, ISSN: 00095893
Eleanor Canova-Davis; Chen; Wassim Nashabeh; Timothy Wehr
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