Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 11401 - 11450 OF 15217 RESULTS

September 4, 2000

Statistical analysis of the long-term effects of recombinant human deoxyribonuclease on pulmonary function in cystic fibrosis patients

Journal of Biopharmaceutical Statistics, ISSN: 10543406

John J. Chen; Scott Hamilton

September 2, 2000

Wnt signaling and cancer

Genes and Development, ISSN: 08909369

Paul G. Polakis

September 1, 2000

A comparison of different methods to determine the end of exponential growth in CHO cell cultures for optimization of scale-up

Biotechnology Progress, ISSN: 87567938

Schoenherr; Stapp; Thomas Ryll

September 1, 2000

The interaction of neuropilin-1 in vascular endothelial growth factor and its receptor Flt-1

Journal of Biological Chemistry, ISSN: 00219258

Fuh; Garcia; De Vos

September 1, 2000

Efficient phage display of polypeptides fused to the carboxy-terminus of the M13 gene-3 minor coat protein

FEBS Letters, ISSN: 00145793

Fuh; Sachdev S. Sidhu

September 1, 2000

Ternary complex between placental lactogen and the extracellular domain of the prolactin receptor

Nature Structural Biology, ISSN: 10728368

Patricia A. Elkins; Hans W. Christinger; Yael Sandowski; Edna Sakal; Arieh Gertler; De Vos; Anthony A. Kossiakoff

August 26, 2000

Antibody binding regions on human nerve growth factor identified by homolog- and alanine-scanning mutagenesis

Hybridoma, ISSN: 0272457X

Hongo; Laramee; Urfer; David L. Shelton; Restivo; Michael D Sadick; Galloway; Chu; Winslow

August 25, 2000

Smoothened activates Gα(i)-mediated signaling in frog melanophores

Journal of Biological Chemistry, ISSN: 00219258

Dianne L. DeCamp; Teresa M. Thompson; Frederic J. De Sauvage; Michael R. Lerner

August 20, 2000

Performance of small-scale CHO perfusion cultures using an acoustic cell filtration device for cell retention: Characterization of separation efficiency and impact of perfusion on product quality

Biotechnology and Bioengineering, ISSN: 00063592

Thomas Ryll; George Dutina; Arthur Reyes; Jane Gunson; Lynne Krummen; Etcheverry

August 18, 2000

Vitronectin receptor antagonists: Purine-based peptidomimetics

Angewandte Chemie - International Edition, ISSN: 14337851

Peyman; Gourvest; Thomas Gadek; Knolle

August 18, 2000

Enzyme mechanisms for polycyclic triterpene formation

Angewandte Chemie - International Edition, ISSN: 14337851

K. Ulrich Wendt; Georg E. Schulz; Elias J. Corey; David R. Liu

August 15, 2000

VEGF regulates cell behavior during vasculogenesis

Developmental Biology, ISSN: 00121606

Christopher J. Drake; Amanda LaRue; Napoleone Ferrara; Charles D. Little

August 11, 2000

The 3' UTR of human MnSOD mRNA hybridizes to a small cytoplasmic RNA and inhibits gene expression

Biochemical and Biophysical Research Communications, ISSN: 0006291X

Joseph J. Stuart; Levente A. Egry; Grace H.W. Wong; Roger L. Kaspar

August 2, 2000

Genetic studies in idiopathic short stature

Current Opinion in Pediatrics, ISSN: 10408703

Kenneth M. Attie

August 1, 2000

Rapid mapping of protein functional epitopes by combinatorial alanine scanning

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Gregory A. Weiss; Colin K. Watanabe; Zhong; Goddard; Sachdev S. Sidhu

August 1, 2000

Electrophoretic methods for the analysis of N-linked oligosaccharides

Analytical Biochemistry, ISSN: 00032697

T. Shantha Raju

August 1, 2000

FIZZ1, a novel cysteine-rich secreted protein associated with pulmonary inflammation, defines a new gene family

EMBO Journal, ISSN: 02614189

Ilona N. Holcomb; Rhona C. Kabakoff; Betty Chan; Thad Baker; Austin L. Gurney; William J. Henzel; Nelson; Henry B. Lowman; Wright; Nicholas J. Skelton; Gretchen D. Frantz; Daniel B. Tumas; Franklin V. Peale Jr.; David L. Shelton; Hébert

August 1, 2000

A repressor sequence in the juxtamembrane domain of Flt-1 (VEGFR-1) constitutively inhibits vascular endothelial growth factor-dependent phosphatidylinositol 3'-kinase activation and endothelial cell migration

EMBO Journal, ISSN: 02614189

Hendrik Gille; Joe Kowalski; Lanlan Yu; Helen Chen; Pisabarro; Terri Davis-Smyth; Napoleone Ferrara

August 1, 2000

Analysis of glycoconjugates: II. Electrophoresis

Analytical Biochemistry, ISSN: 00032697

T. Shantha Raju

July 28, 2000

Identification and cloning of two histone fold motif-containing subunits of HeLa DNA polymerase ε

Journal of Biological Chemistry, ISSN: 00219258

Ying Li; Zachary F. Pursell; Stuart Linn

July 27, 2000

Fringe is a glycosyltransferase that modifies Notch

Nature, ISSN: 00280836

Daniel J. Moloney; Vladislav M. Panin; Stuart H. Johnston; Jihua Chen; Li Shao; Richa Wilson; Yang Wang; Pamela Stanley; Kenneth D. Irvine; Robert S. Haltiwanger; Thomas F. Vogt

July 15, 2000

Increased binding activity at an antioxidant-responsive element in the metallothionein-1 promoter and rapid induction of metallothionein-1 and -2 in response to cerebral ischemia and reperfusion

Journal of Neuroscience, ISSN: 02706474

Menno Van Lookeren Campagne; Harold Thibodeaux; Nicholas Van Bruggen; Cairns; David G Lowe

July 14, 2000

Analysis of PDZ domain-ligand interactions using carboxyl-terminal phage display

Journal of Biological Chemistry, ISSN: 00219258

Fuh; Pisabarro; Ying Li; Quan; Lasky; Sachdev S. Sidhu

July 14, 2000

Interaction of the tumor suppressor PTEN/MMAC with a PDZ domain of MAGI3, a novel membrane-associated guanylate kinase

Journal of Biological Chemistry, ISSN: 00219258

Yan Wu; Dowbenko; Spencer; Richard Laura; James Lee; Qimin Gu; Lasky

July 5, 2000

Purification of plasmid DNA by tangential flow filtration

Biotechnology and Bioengineering, ISSN: 00063592

David W. Kahn; Michelle D. Butler; Darien L. Cohen; Margaret Gordon; Jeanne Kahn; Winkler

July 3, 2000

Sustained release of recombinant human insulin-like growth factor-I for treatment of diabetes

Journal of Controlled Release, ISSN: 01683659

Lam; Duenas; Daugherty; Nancy Levin; Cleland

July 3, 2000

The apoptotic signaling pathway activated by Toll-like receptor-2

EMBO Journal, ISSN: 02614189

Antonios O. Aliprantis; Ruey-Bing Yang; David S. Weiss; Godowski; Arturo Zychlinsky

July 1, 2000

Broad specificity of GDNF family receptors GFRα1 and GFRα2 for GDNF and NTN in neurons and transfected cells

Journal of Neuroscience Research, ISSN: 03604012

Li-Chong Wang; Shih; Hongo; Devaux; Mary Hynes

June 30, 2000

Design evolution of artificial M13 coat proteins

Journal of Molecular Biology, ISSN: 00222836

Gregory A. Weiss; Sachdev S. Sidhu

June 30, 2000

Modulation of tight junction function by G protein-coupled events

Advanced Drug Delivery Reviews, ISSN: 0169409X

Ann M. Hopkins; Dinxi Li; Mrsny; Shaun V. Walsh; Asma Nusrat

June 28, 2000

Development and qualification of a novel virus removal filter for cell culture applications

Biotechnology Progress, ISSN: 87567938

Shengjiang Liu; Mark Carroll; Raquel Iverson; Christine Valera; Vennari; Kimberly Turco; Robert Piper; Robert Kiss; Herbert Lutz

June 28, 2000

Prevalence, clinical characteristics, and mortality among patients with myocardial infarction presenting without chest pain

JAMA - Journal of the American Medical Association, ISSN: 00987484

John G. Canto; Michael G. Shlipak; William J. Rogers; Judith A. Malmgren; Paul D. Frederick; Costas Lambrew; Joseph P. Ornato; Hal V. Barron; Calarina I. Kiefe

June 27, 2000

The tissue factor region that interacts with substrates factor IX and factor X

Biochemistry, ISSN: 00062960

Daniel Kirchhofer; Michael T. Lipari; Paul Moran; Eigenbrot; Robert F. Kelley

June 20, 2000

Ammonium alters N-glycan structures of recombinant TNFR-IgG: Degradative versus biosynthetic mechanisms

Biotechnology and Bioengineering, ISSN: 00063592

Martin Gawlitzek; Thomas Ryll; James A. Lofgren; Mary B. Sliwkowski

June 10, 2000

A phase II study of two HIV type 1 envelope vaccines, comparing their immunogenicity in populations at risk for acquiring HIV type 1 infection

AIDS Research and Human Retroviruses, ISSN: 08892229

M. Juliana McElrath; Lawrence Corey; David Montefiori; Mark Wolff; David Schwartz; Michael C. Keefer; Robert Belshe; Barney S. Graham; Matthews; Peter Wright; Geoffrey Gorse; Raphael Dolin; Berman; Francis; A-M. Duliege; Dani P. Bolognesi; Donald M. Stablein; Nzeera Ketter; Patricia Fast

June 6, 2000

Cockroach diuretic hormones: Characterization of a calcitonin-like peptide in insects

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Kenji Furuya; Richard J. Milchak; Kathleen M. Schegg; Jinrui Zhang; Stephen S. Tobe; Geoffrey M. Coast; David A. Schooley

June 5, 2000

VEGF nuclear accumulation correlates with phenotypical changes in endothelial cells

Journal of Cell Science, ISSN: 00219533

Wenlu Li; Gilbert-Andre Keller

June 1, 2000

Interaction of the TNF homologues BLyS and APRIL with the TNF receptor homologues BCMA and TACI

Current Biology, ISSN: 09609822

Scot A. Marsters; Minhong Yan; Pitti; Philip E. Haas; Vishva M. Dixit; Avi Ashkenazi

June 1, 2000

Immunopolymerase chain reaction using real-time polymerase chain reaction for detection

Analytical Biochemistry, ISSN: 00032697

Paul Sims; Vasser; Wai Lee T. Wong; P. Mickey Williams; Meng

June 1, 2000

Variations on ligand-receptor complexes

Nature Structural Biology, ISSN: 10728368

Wiesmann; De Vos

June 1, 2000

ABRF-98SEQ: Evaluation of peptide sequencing at high sensitivity

Journal of Biomolecular Techniques, ISSN: 15240215 19434731

William J. Henzel; Arie Admon; Steve A. Carr; Gary Davis; Karen De Jongh; William Lane; Michael Rohd; Laurey Steinke

June 1, 2000

Overexpression of Math1 induces robust production of extra hair cells in postnatal rat inner ears

Nature Neuroscience, ISSN: 10976256

Zheng; Gao

May 25, 2000

The volume of primary angioplasty procedures and survival after acute myocardial infarction

New England Journal of Medicine, ISSN: 00284793

John G. Canto; Nathan R. Every; David J. Magid; William J. Rogers; Judith A. Malmgren; Paul D. Frederick; William J. French; Alan J. Tiefenbrunn; Vijay K. Misra; Calarina I. Kiefe; Hal V. Barron

May 16, 2000

Evidence for the involvement of histidine A(12) in the aggregation and precipitation of human relaxin induced by metal-catalyzed oxidation

Biochemistry, ISSN: 00062960

Mehrnaz Khossravi; Steven J. Shire; Ronald T. Borchardt

May 15, 2000

Radiation and the Apo2L/TRAIL apoptotic pathway preferentially inhibit the colonization of premalignant human breast cells overexpressing cyclin D1

Cancer Research, ISSN: 00085472

Qun Zhou; Paula Fukushima; William DeGraff; James B. Mitchell; Maryalice Stetler-Stevenson; Avi Ashkenazi; Patricia S. Steeg

May 15, 2000

Stability and interactions of recombinant human nerve growth factor in different biological matrices: In vitro and in vivo studies

Drug Metabolism and Disposition, ISSN: 00909556

Cindy B. Nguyen; Szonyi; Michael D Sadick; Hotaling; José-Luis Mendoza-Ramírez; Escandon

May 15, 2000

Tissue disposition and pharmacokinetics of recombinant human nerve growth factor after acute and chronic subcutaneous administration in monkeys

Drug Metabolism and Disposition, ISSN: 00909556

Cindy B. Nguyen; Louise A. Harris; Szonyi; Sharon A. Baughman; Victoria Hale; Noel Dybdal; Michael D Sadick; Escandon

May 15, 2000

Structural basis of the Axin-adenomatous polyposis coli interaction

EMBO Journal, ISSN: 02614189

Katharine Eklof Spink; Paul G. Polakis; William I. Weis

May 15, 2000

Pharmacokinetics, tissue distribution, metabolism, and excretion of celecoxib in rats

Drug Metabolism and Disposition, ISSN: 00909556

Susan K. Paulson; Ji Y. Zhang; Alan P. Breau; Jeremy D. Hribar; Norman W. K. Liu; Susan M. Jessen; Yvette M. Lawal; J. Nita Cogburn; Christopher J. Gresk; Charles S. Markos; Timothy J. Maziasz; Grant L. Schoenhard; Earl G. Burton

May 11, 2000

Growth factors: Formation of endothelial cell networks

Nature, ISSN: 00280836

Gabriel Helmlinger; Mitsuhiro Endo; Napoleone Ferrara; Lynn Hlatky; Rakesh K. Jain

Join Our Team

The little things we do every day add up to big breakthroughs. Making a difference in the lives of millions starts when you make a change in yours.

Two Scientists Walk Into a Bar

Two Scientists Walk Into a Bar

Listen to our podcast, where researchers talk about their work answering the toughest questions in human biology.