Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 11451 - 11500 OF 16739 RESULTS

January 1, 2007

Synthetic antibodies as therapeutics

Expert Opinion on Biological Therapy, ISSN: 14712598

Fuh

January 1, 2007

Endpoints for agents that slow tumor growth

Contemporary Clinical Trials, ISSN: 15517144

Ron X. Yu; Holmgren

January 1, 2007

Cell culture process development: Advances in process engineering

Biotechnology Progress, ISSN: 87567938

Carole Heath; Robert Kiss

January 1, 2007

Moisture-induced aggregation of lyophilized DNA and its prevention

Pharmaceutical Research, ISSN: 07248741 1573904X

Vikas Sharma; Klibanov

January 1, 2007

Rapid removal of N-linked oligosaccharides using microwave assisted enzyme catalyzed deglycosylation

International Journal of Mass Spectrometry, ISSN: 13873806

Wendy N. Sandoval; Arellano; David Arnott; Helga Raab; Richard L. Vandlen; Jennie R. Lill

January 1, 2007

Adenoviral expression of XIAP antisense RNA induces apoptosis in glioma cells and suppresses the growth of xenografts in nude mice

Gene Therapy, ISSN: 14765462 09697128

Naumann; Bähr; Wolburg; Altenberend; Wick; Liston; Avi Ashkenazi; Michael Weller

January 1, 2007

Medication costs: The role physicians play with their senior patients

Journal of the American Geriatrics Society, ISSN: 00028614 15325415

Mary Sue Beran; Marianne Laouri; Marika Suttorp; Robert Brook

January 1, 2007

An interferon signature in the peripheral blood of dermatomyositis patients is associated with disease activity

Molecular Medicine, ISSN: 10761551

Emily C. Baechler; Jason W. Bauer; Catherine A. Slattery; Ward Ortmann; Karl J. Espe; Jill Novitzke; Steven R. Ytterberg; Peter K. Gregersen; Timothy W. Behrens; Ann M. Reed

January 1, 2007

Imaging tumors with an albumin-binding Fab, a novel tumor-targeting agent

Cancer Research, ISSN: 00085472

Dennis; Hongkui Jin; Dugger; Renhui Yang; Leanne McFarland; Annie Ogasawara; Simon P. Williams; Mary J. Cole; Ross; Ralph H. Schwall

January 1, 2007

Postnatal induction of transforming growth factor β signaling in fibroblasts of mice recapitulates clinical, histologic, and biochemical features of scleroderma

Arthritis and Rheumatism, ISSN: 00043591

Sonali Sonnylal; Christopher P. Denton; Bing Zheng; Douglas R. Keene; Ruming He; Henry P. Adams; Carolyn S. VanPelt; Yong J. Geng; Jenny M. Deng; Richard R. Behringer; Benoit De Crombrugghe

January 1, 2007

Streptolysin O enhances keratinocyte migration and proliferation and promotes skin organ culture wound healing in vitro

Wound Repair and Regeneration, ISSN: 10671927 1524475X

Marjana Tomic-Canic; Stephen W. Mamber; Olivera Stojadinovic; Brian Lee; Nadezda Radoja; John McMichael

January 1, 2007

Inflammasome adaptors and sensors: Intracellular regulators of infection and inflammation

Nature Reviews Immunology, ISSN: 14741733

Sanjeev Mariathasan; Denise M. Monack

January 1, 2007

Ubiquitination screen using protein microarrays for comprehensive identification of Rsp5 substrates in yeast

Molecular Systems Biology, ISSN: 17444292 17444292

Ronish Gupta; Bart Kus; Christopher Fladd; James Wasmuth; Raffi Tonikian; Sachdev S. Sidhu; Nevan J. Krogan; John Parkinson; Daniela Rotin

January 1, 2007

Is Hydroxocobalamin Safe and Effective for Smoke Inhalation? Searching for Guidance in the Haze

Annals of Emergency Medicine, ISSN: 01960644

Andrew R. Erdman

January 1, 2007

Natural Killer or Dendritic: What's in a Name?

Immunity, ISSN: 10747613

Hergen Spits; Lewis L. Lanier

January 1, 2007

Protein NMR Spectroscopy

Protein NMR Spectroscopy,

John Cavanagh; Wayne J. Fairbrother; Arthur G. Palmer III; Nicholas J. Skelton; Mark Rance

January 1, 2007

The Hh signaling pathway in cancer.

Bulletin et mémoires de l'Académie royale de médecine de Belgique, ISSN: 03778231

Frederic J. De Sauvage

January 1, 2007

Ranibizumab for Predominantly Classic Neovascular Age-related Macular Degeneration: Subgroup Analysis of First-year ANCHOR Results

American Journal of Ophthalmology, ISSN: 00029394

Peter K. Kaiser; David M. Brown; Kang Zhang; Henry L. Hudson; Frank G. Holz; Howard Shapiro; Susan Schneider; Nisha R. Acharya

January 1, 2007

Human-derived clotting agent avoids immunogenicity

Managed Care, ISSN: 10623388

Thomas Morrow

January 1, 2007

On the determination of the time delay in reaching the steady state drug concentration in the organ compared to plasma

Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549

Leonid M. Berezhkovskiy

January 1, 2007

Risk factors associated with persistent airflow limitation in severe or difficult-to-treat asthma: Insights from the TENOR study

Chest, ISSN: 00123692

June H. Lee; Tmirah Haselkorn; Larry Borish; Lawrence Rasouliyan; Bradley E. Chipps; Sally E. Wenzel

January 1, 2007

Should clinical complications affect USDA pain categories? C is correct.

Lab Animal, ISSN: 00937355

Gail T. Colbern; Lisa Heath

January 1, 2007

Cryoablation for atrial flutter requires no anesthesia

Managed Care, ISSN: 10623388

Thomas Morrow

January 1, 2007

A self-developed prechemotherapy education checklist.

Clinical journal of oncology nursing, ISSN: 10921095

Peggy S Mueller; Catherine A Glennon

January 1, 2007

A naturally occurring truncated β3 integrin in tumor cells: Native anti-integrin involved in tumor cell motility

Cancer Biology and Therapy, ISSN: 15558576 15384047

Rongxian Jin; Mohit Trikha; Yinlong Cai; David Grignon; Kenneth V. Honn

January 1, 2007

Angiographic and Optical Coherence Tomographic Results of the MARINA Study of Ranibizumab in Neovascular Age-Related Macular Degeneration

Ophthalmology, ISSN: 01616420

Peter K. Kaiser; Barbara A. Blodi; Howard Shapiro; Nisha R. Acharya

January 1, 2007

Gene expression microarray improves prediction of breast cancer outcomes

Managed Care, ISSN: 10623388

Thomas Morrow

January 1, 2007

Risk Factors For Rate of Decline in Forced Expiratory Volume in One Second in Children and Adolescents with Cystic Fibrosis

Journal of Pediatrics, ISSN: 00223476

Michael W. Konstan; Morgan; Butler; David J. Pasta; Marcia L. Craib; Stefanie J. Silva; Dennis C. Stokes; Mary Ellen Wohl; Wagener; Warren E. Regelmann; Charles A. Johnson

January 1, 2007

Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion

Nature Cell Biology, ISSN: 14657392

Katarina Wolf; Yi I. Wu; Yueying Liu; Jörg Geiger; Eric Tam; Christopher Overall; M. Sharon Stack; Peter Friedl

January 1, 2007

The effect of cosolutes on the isomerization of aspartic acid residues and conformational stability in a monoclonal antibody

Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549

Aditya A. Wakankar; Jun Liu; David Vandervelde; Y. John Wang; Steven J. Shire; Ronald T. Borchardt

January 1, 2007

Implications of pharmacogenomics in the current and future treatment of asthma

Journal of Managed Care Pharmacy, ISSN: 10834087

Thomas Morrow

January 1, 2007

Lack of augmentation of tumor spectrum or severity in dual heterozygous Men1 and Rb1 knockout mice

Oncogene, ISSN: 14765594 09509232

Loffler; Biondi; Gartside; Serewko-Auret; Duncan; Tonks; Mould; Waring; Muller; Kay; Hayward

January 1, 2007

Progressive Fibrosis in Nonalcoholic Steatohepatitis: Association With Altered Regeneration and a Ductular Reaction

Gastroenterology, ISSN: 00165085

Michelle M. Richardson; Julie R. Jonsson; Elizabeth E. Powell; Elizabeth M. Brunt; Brent A. Neuschwander-Tetri; Prithi S. Bhathal; John B. Dixon; Martin D. Weltman; Herbert Tilg; Alexander R. Moschen; David M. Purdie; Anthony J. Demetris; Andrew D. Clouston

January 1, 2007

Cox regression methods for two-stage randomization designs

Biometrics, ISSN: 15410420 0006341X

Yuliya Lokhnygina; Jeffrey D. Helterbrand

January 1, 2007

Fluid support worsens outcome and negates the benefit of protective antigen-directed monoclonal antibody in a lethal toxin-infused rat Bacillus anthracis shock model

Critical Care Medicine, ISSN: 00903493

Kevin Sherer; Yan Li; Xizhong Cui; Xuemei Li; Mani Subramanian; Mike Laird; Mahtab Moayeri; Stephen H. Leppla; Yvonne Fitz; Junwu Su; Peter Q. Eichacker

January 1, 2007

ADDRESS (ADministration of DRotrecogin alfa [activated] in Early stage Severe Sepsis) long-term follow-up: One-year safety and efficacy evaluation

Critical Care Medicine, ISSN: 00903493

Pierre-Francois Laterre; Edward Abraham; Jonathan M. Janes; Benjamin L. Trzaskoma; Nancy L. Correll; Frank V. Booth

January 1, 2007

Strategies for successful lyophilization process scale-up

American Pharmaceutical Review, ISSN: 10998012

Samir Sane; Chung C. Hsu

January 1, 2007

A phase II, randomized, doubleblind, parallelgroup, placebocontrolled oral food challenge trial of Xolair (omalizumab) in peanut allergy

Journal of Allergy and Clinical Immunology, ISSN: 00916749

Hugh A. Sampson; Donald Y.M. Leung; A. Wesley Burks; Gideon Lack; Sami L. Bahna; Stacie M. Jones; Dennis A. Wong

January 1, 2007

Validation of analytical procedures and physical methods

Validation of Pharmaceutical Processes, Third Edition,

Hélène Gazzano-Santoro; Broughton; Dieter Schmalzing

December 25, 2006

Cardiotrophin-1 defends the liver against ischemia-reperfusion injury and mediates the protective effect of ischemic preconditioning

Journal of Experimental Medicine, ISSN: 00221007 00221007

Maria Iñiguez; Carmen Berasain; Eduardo Martinez-Ansó; Matilde Bustos; Puri Fortes; Diane Pennica; Matias A. Avila; Jesús Prieto

December 21, 2006

Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis

Nature, ISSN: 14764687 00280836

John B.B. Ridgway; Gu Zhang; Yan Wu; Scott Stawicki; Wei-Ching Liang; Yvan Chanthery; Joe Kowalski; Ryan J. Watts; Christopher Callahan; Ian Kasman; Mallika Singh; May Chien; Christine Tan; Hongo; Frederic J. De Sauvage; Greg D. Plowman; Minhong Yan

December 15, 2006

Inhibition of carcinoma cell-derived VEGF reduces inflammatory characteristics in xenograft carcinoma

International Journal of Cancer, ISSN: 00207136 10970215

Alexei V. Salnikov; Nils-Erik Heldin; Linda B. Stuhr; Helge Wiig; Hans-Peter Gerber; Rolf K. Reed; Kristofer Rubin

December 13, 2006

Making antibodies in bacteria

Making and Using Antibodies: A Practical Handbook,

Frederic A. Fellouse; Sachdev S. Sidhu

December 5, 2006

An exclusion mechanism in ion exchange chromatography

Biotechnology and Bioengineering, ISSN: 00063592 10970290

Chithkala Harinarayan; Jay Mueller; Anders Ljunglöf; Fahrner; James M. Van Alstine; Van Reis

December 1, 2006

Concluding summary: Proceedings of the AAPS Biotec Open Forum on "Aggregation of Protein Therapeutics"

AAPS Journal, ISSN: 15507416

Steven J. Shire; Cromwell; Jun Liu

December 1, 2006

Sustained benefit in rheumatoid arthritis following one course of rituximab: Improvements in physical function over 2 years

Rheumatology, ISSN: 14620324 14620332

Vibeke Strand; Balbir-Gurman; Karel Pavelka; Paul Emery; Nicole F. Li; Ming Yin; Lehane; Sunil Agarwal

December 1, 2006

Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling

Molecular and Cellular Proteomics, ISSN: 15359476

Pierre-Olivier Angrand; Inmaculada Segura; Pamela Völkel; Sonja Ghidelli; Rebecca Terry; Miro Brajenovic; Kristina Vintersten; Rüdiger Klein; Giulio Superti-Furga; Gerard Drewes; Bernhard Kuster; Tewis Bouwmeester; Amparo Acker-Palmer

December 1, 2006

Genetics of autoimmune diseases - Disorders of immune homeostasis

Nature Reviews Genetics, ISSN: 14710056 14710064

Peter K. Gregersen; Timothy W. Behrens

December 1, 2006

Glucuronidation in the chimpanzee (Pan troglodytes): Studies with acetaminophen, oestradiol and morphine

Xenobiotica, ISSN: 00498254 13665928

Harvey Wong; James E. Grace Jr.; Matthew Wright; Browning; Grossman; Bai; David D. Christ

December 1, 2006

Enhanced half-life of genetically engineered human IgG1 antibodies in a humanized FcRn mouse model: Potential application in humorally mediated autoimmune disease

International Immunology, ISSN: 09538178 14602377

Stefka B. Petkova; Shreeram Akilesh; Thomas J. Sproule; Gregory J. Christianson; Hana Al Khabbaz; Aaron C. Brown; Presta; Meng; Derry C. Roopenian

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