Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 11601 - 11650 OF 15217 RESULTS

Pharmacokinetics and pharmacodynamics of tenecteplase: Results from a phase II study in patients with acute myocardial infarction
Journal of Clinical Pharmacology, ISSN: 00912700
Modi; Fox; Fong-Wong Clow; Tanswell; Christopher P. Cannon; Frans Van De Werf; Eugene Braunwald
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Mice lacking α-synuclein display functional deficits in the nigrostriatal dopamine system
Neuron, ISSN: 08966273
Asa Abeliovich; Yvonne Schmitz; Isabel Fariñas; Choi-Lundberg; Ho; Pablo E. Castillo; Natasha Shinsky; Jose Manuel Garcia-Verdugo; Armanini; Anne Ryan; Mary Hynes; Phillips; David Sulzer; Rosenthal
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Purification of yeast mitochondrial Hsp60.
Methods in Molecular Biology, ISSN: 10643745
Yves Dubaquié; Renate Looser; Sabine Rospert
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Drug information in industry versus academia: A pharmacy resident's perspective of a sample case
Therapeutic Innovation and Regulatory Science, ISSN: 21684790
Graham; David A. Graves; Barry Grobman; Gary M. Mccart; Candy Tsourounis
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Comparison of the rates of deamidation, diketopiperazine formation, and oxidation in recombinant human vascular endothelial growth factor and model peptides
AAPS PharmSci, ISSN: 15221059
Chimanlall Goolcharran; Andrew J.S. Jones; Ronald T. Borchardt; Cleland; Rodney Keck
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Characterization of huJAM: Evidence for involvement in cell-cell contact and tight junction regulation
American Journal of Physiology - Cell Physiology, ISSN: 03636143
Tony W. Liang; Richard A. Demarco; Mrsny; Austin L. Gurney; Gray; Jeff Hooley; Holly L. Aaron; Arthur Huang; Toni Klassen; Daniel B. Tumas; Fong
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Expression of activated CDC42 induces T cell apoptosis in thymus and peripheral lymph organs via different pathways
Oncogene, ISSN: 09509232
Songqing Na; Baiyong Li; Iqbal S. Grewal; Hervé Enslen; Roger J. Davis; Jeffrey H. Hanke; Richard A. Flavell
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Treatment of allergic asthma with monoclonal anti-IgE antibody
New England Journal of Medicine, ISSN: 00284793
Henry Milgrom; Robert B. Fick Jr.; John Q. Su; Reimann; Robert K. Bush; Marc Watrous; W. James Metzger
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Baculovirus-based genetic screen for antiapoptotic genes identifies a novel IAP
Journal of Biological Chemistry, ISSN: 00219258
Somasekar Seshagiri; Domagoj Vucic; James Lee; Vishva M. Dixit
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Functional interaction between Gα(z) and Rap1GAP suggests a novel form of cellular cross-talk
Journal of Biological Chemistry, ISSN: 00219258
Jingwei Meng; Jennifer L. Glick; Paul G. Polakis; Patrick J. Casey
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Autosomal recessive chronic granulomatous disease caused by novel mutations in NCF-2, the gene encoding the p67-phox component of phagocyte NADPH oxidase
Human Genetics, ISSN: 03406717
Noack; Julie Rae; Andrew R. Cross; José Muñoz; Siham Salmen; José A. Mendoza; Nineth Rossi; John T. Curnutte; Heyworth
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Overexpression of thioredoxin h leads to enhanced activity of starch debranching enzyme (pullulanase) in barley grain
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Myeong-Je Cho; Joshua H. Wong; Corina Marx; Jiang; Peggy G. Lemaux; Bob B. Buchanan
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Development of bivalent (B/E) vaccines able to neutralize CCR5-dependent viruses from the United States and Thailand
Virology, ISSN: 00426822
Berman; Wei Huang; Riddle; Gray; Wrin; Vennari; Johnson; Michael Klaussen; Prashad; Christiane Köhne; Christina De Wit; Timothy Gregory
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Chapter 3.1.10 Targeting genes associated with mammalian behavior: past mistakes and future solutions
Techniques in the Behavioral and Neural Sciences, ISSN: 09210709
Gerlai
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Preface. Behavioral neurogenetics: the new synthesis
Techniques in the Behavioral and Neural Sciences, ISSN: 09210709
Wim E. Crusio; Gerlai
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Characterization of the human Suppressor of fused, a negative regulator of the zinc-finger transcription factor Gli
Journal of Cell Science, ISSN: 00219533
Donna Stone; Maximilien Murone; Shiuh-Ming Luoh; Weilan Ye; Armanini; Austin L. Gurney; Phillips; Brush; Goddard; Frederic J. De Sauvage; Rosenthal
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Clinical applications of angiogenic growth factors and their inhibitors
Nature Medicine, ISSN: 10788956
Napoleone Ferrara; Kari Alitalo
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Chapter 3.2.7 Protein targeting in the functional analysis of EphA receptors: the use of immunoadhesins
Techniques in the Behavioral and Neural Sciences, ISSN: 09210709
Gerlai; Natasha Shinsky; Shih; P. Mickey Williams; Jane Winer; Armanini; Paul Moran; Cairns; Winslow; Gao; Phillips
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Activation of microglia reveals a non-proteolytic cytokine function for tissue plasminogen activator in the central nervous system
Journal of Cell Science, ISSN: 00219533
Andrew D. Rogove; Chia-Jen Siao; Keyt; Sidney Strickland; Stella E. Tsirka
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Recovery of severe sciatica
Spine, ISSN: 03622436
Federico Balagué; Margareta Nordin; Ali Sheikhzadeh; Anne-Catherine Echegoyen; Helena Brisby; Henri Marcel Hoogewoud; Pam Fredman; Mary Louise Skovron
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Chapter 2.2.4 Application of real-time RT-PCR for quantification of gene expression
Techniques in the Behavioral and Neural Sciences, ISSN: 09210709
Jane Winer; Natasha Shinsky; Gerlai; P. Mickey Williams
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Chapter 4.1 Ethological approaches in behavioral neurogenetic research
Techniques in the Behavioral and Neural Sciences, ISSN: 09210709
Gerlai
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Chapter 3.2.6 The use of immunoadhesins in neurobiology
Techniques in the Behavioral and Neural Sciences, ISSN: 09210709
David L. Shelton
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Control of apoptosis signaling by Apo2 ligand
Recent Progress in Hormone Research, ISSN: 00799963
Scot A. Marsters; Pitti; James P. Sheridan; Avi Ashkenazi
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Smaug, a novel and conserved protein, contributes to repression of nanos mRNA translation in vitro
RNA, ISSN: 13558382
Craig A. Smibert; Yung S. Lie; Wendy Shillinglaw; William J. Henzel; Paul M. Macdonald
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Prolonging cell-free protein synthesis with a novel ATP regeneration system
Biotechnology and Bioengineering, ISSN: 00063592
Dong-Myung Kim; James R. Swartz
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Chapter 2.1.8 Mutagenesis in zebra fish: studying the brain dopamine systems
Techniques in the Behavioral and Neural Sciences, ISSN: 09210709
Guo; Wolfgang Driever; Rosenthal
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Role of oestrogen therapy in the management of short stature in Turner syndrome
Acta Paediatrica, International Journal of Paediatrics, Supplement, ISSN: 08035326
Chernausek; Kenneth M. Attie
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Recombinant tissue-type plasminogen activator (Alteplase) for ischemic stroke 3 to 5 hours after symptom onset the ATLANTIS study: A randomized controlled trial
JAMA - Journal of the American Medical Association, ISSN: 00987484
Wayne M. Clark; Stanley Wissman; Gregory W. Albers; Jack H. Jhamandas; Kenneth Madden; Scott Hamilton
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Secretion of glycosylation site mutants can be rescued by the signal/pro sequence of tissue plasminogen activator
Journal of Cellular Biochemistry, ISSN: 07302312
Christiane Köhne; Johnson; Sabrina Tom; Peers; Richard L. Gehant; Hotaling; Dave Brousseau; Thomas Ryll; Judy Fox; Steven M. Chamow; Berman
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Validation of a rat pheochromocytoma (PC12)-based cell survival assay for determining biological potency of recombinant human nerve growth factor
Journal of Pharmaceutical and Biomedical Analysis, ISSN: 07317085
Hélène Gazzano-Santoro; Chen; Barbara Casto; Chu; Ellen Gilkerson; Mukku; Eleanor Canova-Davis; Claire Kotts
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Napsin A, a member of the aspartic protease family, is abundantly expressed in normal lung and kidney tissue and is expressed in lung adenocarcinomas
FEBS Letters, ISSN: 00145793
Yoshiko Chuman; Ann-Charlotte Bergman; Takayuki Ueno; Shin'Ichi Saito; Kazuyasu Sakaguchi; Ayodele A. Alaiya; Bo Franzén; Tomas Bergman; David Arnott; Gert Auer; Ettore Appella; Hans Jörnvall; Stig Linder
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Hedgehog signal transduction: From flies to vertebrates
Experimental Cell Research, ISSN: 00144827
Maximilien Murone; Rosenthal; Frederic J. De Sauvage
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Establishing equivalence by showing that a specified percentage of the effect of the active control over placebo is maintained
Journal of Biopharmaceutical Statistics, ISSN: 10543406
Holmgren
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RIP2 is a Raf1-activated mitogen-activated protein kinase kinase
Journal of Biological Chemistry, ISSN: 00219258
Tony A. Navas; Daryl T. Baldwin; Stewart
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Locoregional Apo2L/TRAIL eradicates intracranial human malignant glioma xenografts in athymic mice in the absence of neurotoxicity
Biochemical and Biophysical Research Communications, ISSN: 0006291X
Wilfried Roth; Stefan Isenmann; Ulrike Naumann; Sebastian Kügler; Mathias Bähr; Johannes Dichgans; Avi Ashkenazi; Michael Weller
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Early use of ACE inhibitors in the treatment of acute myocardial infarction in the united states: Experience from the National Registry of Myocardial Infarction 2
American Journal of Cardiology, ISSN: 00029149
Andrew D. Michaels; Charles Maynard|; Nathan R. Every; Hal V. Barron
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Equivalence trials in SLE research: Issues to consider
Lupus, ISSN: 09612033
Mimi Y. Kim; Jill P. Buyon; Michelle Petri; Mary Louise Skovron; Roy E. Shore
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Putting two and two together: Crystal structure of the FGF-receptor complex
Structure, ISSN: 09692126
Wiesmann; De Vos
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Carbohydrate analysis of a chimeric recombinant monoclonal antibody by capillary electrophoresis with laser-induced fluorescence detection
Analytical Chemistry, ISSN: 00032700
Stacey; Wassim Nashabeh
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Vascular endothelial growth factor governs endothelial nitric-oxide synthase expression via a KDR/Flk-1 receptor and a protein kinase C signaling pathway
Journal of Biological Chemistry, ISSN: 00219258
Shen; David Y. Lee; Zioncheck
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Electrophysiological and antiarrhythmic effects of the atrial selective 5-HT4 receptor antagonist RS-100302 in experimental atrial flutter and fibrillation
Circulation, ISSN: 00097322
Marc M. Rahme; Bruno Cotter; Elisabeth Leistad; Manish K. Wadhwa; Rajendra Mohabir; Anthony P. D. W. Ford; Richard M. Eglen; Gregory K. Feld
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Selection and analysis of an optimized Anti-VEGF antibody: Crystal structure of an affinity-matured Fab in complex with antigen
Journal of Molecular Biology, ISSN: 00222836
Chen; Wiesmann; Fuh; Bing Li; Hans W. Christinger; McKay; De Vos; Henry B. Lowman
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Engineering Chinese hamster ovary cells to maximize sialic acid content of recombinant glycoproteins
Nature Biotechnology, ISSN: 10870156
Weikert; Damon I. Papac; Briggs; Cowfer; Sabrina Tom; Martin Gawlitzek; James A. Lofgren; Mehta; Chisholm; Modi; Stephen M. Eppler; Carroll; Steven M. Chamow; Peers; Berman; Lynne Krummen
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Regulation of learning by EphA receptors: A protein targeting study
Journal of Neuroscience, ISSN: 02706474
Gerlai; Natasha Shinsky; Shih; P. Mickey Williams; Jane Winer; Armanini; Cairns; Winslow; Gao; Phillips
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Weight-adjusted dosing of TNK-tissue plasminogen activator and its relation to angiographic outcomes in the thrombolysis in myocardial infarction 10B trial
American Journal of Cardiology, ISSN: 00029149
C.Michael Gibson; Christopher P. Cannon; Sabina A. Murphy; A.A. Jennifer Adgey; Marc J. Schweiger; Rafael F. Sequeira; Gilles Grollier; Fox; Berioli; W.Douglas Weaver; Frans Van De Werf; Eugene Braunwald
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Solution structure of the VEGF-binding domain of Flt-1: Comparison of its free and bound states
Journal of Molecular Biology, ISSN: 00222836
Melissa A. Starovasnik; Hans W. Christinger; Wiesmann; Mark Champe; De Vos; Nicholas J. Skelton
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Biologic effects of heregulin/neu differentiation factor on normal and malignant human breast and ovarian epithelial cells
Oncogene, ISSN: 09509232
Zuleima Aguilar; Robert W. Akita; Richard S. Finn; B. Lillian Ramos; Pegram; Fairooz F. Kabbinavar; Pietras; Paul Pisacane; Mark X. Sliwkowski; Dennis J. Slamon
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Evidence for a protective role of metallothionein-1 in focal cerebral ischemia
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Menno Van Lookeren Campagne; Harold Thibodeaux; Nicholas Van Bruggen; Cairns; Gerlai; James T. Palmer; Simon P. Williams; David G Lowe
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Performance comparison of Protein A affinity-chromatography sorbents for purifying recombinant monoclonal antibodies
Biotechnology and Applied Biochemistry, ISSN: 08854513
Fahrner; Duncan H. Whitney; Vanderlaan; Gregory S. Blank
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