Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 11751 - 11800 OF 15217 RESULTS

April 2, 1999

Expression and characterization of a DNase I-Fc fusion enzyme

Journal of Biological Chemistry, ISSN: 00219258

Dwyer; Arthur Huang; Clark Q. Pan; Lazarus

April 1, 1999

Apoptosis control by death and decoy receptors

Current Opinion in Cell Biology, ISSN: 09550674

Avi Ashkenazi; Vishva M. Dixit

April 1, 1999

Inhibitory effects of combinations of HER-2/neu antibody and chemotherapeutic agents used for treatment of human breast cancers

Oncogene, ISSN: 09509232

Pegram; Sheree Hsu; Gail D. Lewis; Pietras; Malgorzata Beryt; Mark X. Sliwkowski; Daniel Coombs; Deborah L. Baly; Fairooz F. Kabbinavar; Dennis J. Slamon

April 1, 1999

Transcellular uptake mechanisms of the intestinal epithelial barrier - Part one

Pharmaceutical Science and Technology Today, ISSN: 14615347

Daugherty; Mrsny

March 26, 1999

Caspase-9 can be activated without proteolytic processing

Journal of Biological Chemistry, ISSN: 00219258

Henning R. Stennicke; Quinn L. Deveraux; Eric W. Humke; John C. Reed; Vishva M. Dixit; Guy S. Salvesen

March 26, 1999

Binding specificities and affinities of egf domains for ErbB receptors

FEBS Letters, ISSN: 00145793

Jennifer T. Jones; Robert W. Akita; Mark X. Sliwkowski

March 26, 1999

Peroxisome proliferator-activated receptor γ ligands are potent inhibitors of angiogenesis in vitro and in vivo

Journal of Biological Chemistry, ISSN: 00219258

Xiaohua Xin; Suya Yang; Joe Kowalski; Mary E. Gerritsen

March 19, 1999

Slit proteins bind robo receptors and have an evolutionarily conserved role in repulsive axon guidance

Cell, ISSN: 00928674

Katja Brose; Kimberly S. Bland; Hong Wang Kuan; David Arnott; William J. Henzel; Corey S. Goodman; Marc Tessier-Lavigne; Thomas Kidd

March 19, 1999

Biochemical purification of a mammalian slit protein as a positive regulator of sensory axon elongation and branching

Cell, ISSN: 00928674

Hong Wang Kuan; Katja Brose; David Arnott; Thomas Kidd; Corey S. Goodman; William J. Henzel; Marc Tessier-Lavigne

March 16, 1999

Insulin-like growth factor 1 is required for G2 progression in the estradiol-induced mitotic cycle

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Adesanya; Jian Zhou; Samathanam; Powell-Braxton; Carolyn Bondy

March 15, 1999

Immunocytochemical and morphological evidence for intracellular self- repair as an important contributor to mammalian hair cell recovery

Journal of Neuroscience, ISSN: 02706474

Zheng; Gilbert-Andre Keller; Gao

March 9, 1999

Autophosphorylation dependent destabilization of the insulin receptor kinase domain: Tryptophan-1175 reports changes in the catalytic cleft

Biochemistry, ISSN: 00062960

Steven M. Bishop; J. B. Alexander Ross; Ronald A. Kohanski

March 8, 1999

Protein tyrosine phosphatase-PEST regulates focal adhesion disassembly, migration, and cytokinesis in fibroblasts

Journal of Cell Biology, ISSN: 00219525

Alexandre Angers-Loustau; Jean-François Côté; Alain Charest; Dowbenko; Spencer; Lasky; Michel L. Tremblay

March 1, 1999

Mucosal administration of a chimera composed of Pseudomonas exotoxin and the gp120 V3 loop sequence of HIV-1 induces both salivary and serum antibody responses

Vaccine, ISSN: 0264410X

Mrsny; Daugherty; Charlotte M. Fryling; David FitzGerald

March 1, 1999

VEGF is required for growth and survival in neonatal mice

Development (Cambridge), ISSN: 09501991

Hans-Peter Gerber; Kenneth J. Hillan; Anne Ryan; Joe Kowalski; Gilbert-Andre Keller; Linda Rangell; Wright; Freddy Radtke; Michel Aguet; Napoleone Ferrara

March 1, 1999

Platelet activation in patients after an acute coronary syndrome: Results from the TIMI-12 trial

Journal of the American College of Cardiology, ISSN: 07351097

Kenneth A. Ault; Christopher P. Cannon; Jane Mitchell; John McCahan; Russell P. Tracy; Novotny; Reimann; Eugene Braunwald

March 1, 1999

Targeting therapeutic molecules to cell organelles

American Chemical Society, Polymer Preprints, Division of Polymer Chemistry, ISSN: 00323934

Gilbert-Andre Keller

March 1, 1999

ABRF-97 SEQ: Sequencing results of a low-level sample

Journal of Biomolecular Techniques, ISSN: 15240215 19434731

Kathryn Stone; Joseph Fernandez; Arie Admon; William J. Henzel; William Lane; Michael Rohde; Laurey Steinke

February 25, 1999

Identification of a new member of the tumor necrosis factor family and its receptor, a human ortholog of mouse GITR

Current Biology, ISSN: 09609822

Austin L. Gurney; Scot A. Marsters; Arthur Huang; Pitti; Melanie R Mark; Daryl T. Baldwin; Gray; Patrick Dowd; Brush; Sherry Heldens; Peter Schow; Goddard; William I. Wood; Kevin Baker; Godowski; Avi Ashkenazi

February 19, 1999

Exposure of human vascular endothelial cells to sustained hydrostatic pressure stimulates proliferation: Involvement of the α(V) integrins

Circulation Research, ISSN: 00097330

Eric A. Schwartz; Rena Bizios; Marvin S. Medow; Mary E. Gerritsen

February 18, 1999

Effect of growth hormone treatment on adult height of children with idiopathic short stature

New England Journal of Medicine, ISSN: 00284793

Hintz; Kenneth M. Attie; Joyce Baptista; Roche

February 17, 1999

Effects of chronic renal failure and growth hormone on serum levels of insulin-like growth factor-binding protein-4 (IGFBP-4) and IGFBP-5 in children: A report of the southwest pediatric nephrology study group

Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X

David R. Powell; Susan K. Durham; Eileen D. Brewer; James W. Frane; Sandra L. Watkins; Ronald J. Hogg; Subburaman Mohan

February 15, 1999

Spontaneous activation of NADPH oxidase in a cell-free system: Unexpected multiple effects of magnesium ion concentrations

Biochemical Journal, ISSN: 02646021

Andrew R. Cross; Erickson; Beverly A. Ellis; John T. Curnutte

February 15, 1999

Structure of a CXC chemokine-receptor fragment in complex with interleukin-8

Structure, ISSN: 09692126

Nicholas J. Skelton; Quan; Dorothea Reilly; Henry B. Lowman

February 2, 1999

Recombinant human Dnase I (rhDNase) in patients with lupus nephritis

Lupus, ISSN: 09612033

John C. Davis; Manzi; Yarboro; Rairie; McInnes; Averthelyi; Sinicropi; Victoria Hale; Balow; Austin; Boumpas; Klippel

February 1, 1999

Protein identification using 20-minute Edman cycles and sequence mixture analysis

Analytical Biochemistry, ISSN: 00032697

William J. Henzel; Jake Tropea; David Dupont

February 1, 1999

Incorporation of 15N from ammonium into the N-linked oligosaccharides of an immunoadhesin glycoprotein expressed in Chinese hamster ovary cells

Glycobiology, ISSN: 09596658

Martin Gawlitzek; Damon I. Papac; Mary B. Sliwkowski; Thomas Ryll

February 1, 1999

Specification of dopaminergic and serotonergic neurons in the vertebrate CNS

Current Opinion in Neurobiology, ISSN: 09594388

Mary Hynes; Rosenthal

February 1, 1999

The domains of death: Evolution of the apoptosis machinery

Trends in Biochemical Sciences, ISSN: 09680004

Aravind; Vishva M. Dixit; Eugene V. Koonin

February 1, 1999

Analysing hippocampal function in transgenic mice: An ethological perspective

Trends in Neurosciences, ISSN: 01662236

Gerlai; Nicola S. Clayton

January 29, 1999

UCP4, a novel brain-specific mitochondrial protein that reduces membrane potential in mammalian cells

FEBS Letters, ISSN: 00145793

Mao; Yu; Zhong; Wenlu Li; Brush; Steve Sherwood; Adams; Pan

January 28, 1999

Sonic hedgehog signaling by the patched-smoothened receptor complex

Current Biology, ISSN: 09609822

Maximilien Murone; Rosenthal; Frederic J. De Sauvage

January 26, 1999

Factor VIIa's first epidermal growth factor-like domain's role in catalytic activity

Biochemistry, ISSN: 00062960

Jianping Jin; Jinli Chang; Jen-Yea Chang; Robert F. Kelley; Darrel W. Stafford; David L. Straight

January 22, 1999

Developmental expression and co-localization of cyclin G1 and the B' subunits of protein phosphatase 2a in neurons

Molecular Brain Research, ISSN: 0169328X

Menno Van Lookeren Campagne; Koji Okamoto; Carol Prives; Ramanjit Gill

January 22, 1999

Trophic effects of cardiotrophin-1 and interleukin-11 on rat dorsal root ganglion neurons in vitro

Molecular Brain Research, ISSN: 0169328X

Michael Thier; Mark Hall; John K. Heath; Diane Pennica; Joachim Weis

January 20, 1999

A simple, two-component buffer enhances use of chromatofocusing for processing of therapeutic proteins

Biotechnology and Bioengineering, ISSN: 00063592

Kathleen A. Logan; Inger Lagerlund; Steven M. Chamow

January 19, 1999

Oncogenic ras fails to restore an in vivo tumorigenic phenotype in embryonic stem cells lacking vascular endothelial growth factor (VEGF)

Biochemical and Biophysical Research Communications, ISSN: 0006291X

Yu-Ping Shi; Napoleone Ferrara

January 19, 1999

Permissive role of thrombopoietin and granulocyte colony-stimulating factor receptors in hematopoietic cell fate decisions in vivo

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Ruedi Stoffel; Sandra Ziegler; Nico Ghilardi; Birgit Ledermann; Frederic J. De Sauvage; Radek C. Skoda

January 19, 1999

Involvement of regulatory and catalytic subunits of phosphoinositide 3-kinase in NF-κB activation

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Christophe Béraud; William J. Henzel; Patrick A. Baeuerle

January 11, 1999

Molecular analysis of chronic granulomatous disease caused by defects in gp91-phox

Human Mutation, ISSN: 10597794

Pablo Patino; Juan E. Perez; Juan A. Lopez; Antonio Condino-Neto; Anete S. Grumach; Jorge H. Botero; John T. Curnutte; Diana García De Olarte

January 8, 1999

A discrete three-amino acid segment (LVI) at the C-terminal end of kinase-impaired ErbB3 is required for transactivation of ErbB2

Journal of Biological Chemistry, ISSN: 00219258

Gabriele Schaefer; Robert W. Akita; Mark X. Sliwkowski

January 8, 1999

Non-flammable preparative reversed-phase liquid chromatography of recombinant human insulin-like growth factor-I

Journal of Chromatography A, ISSN: 00219673

Fahrner; Philip M. Lester; Gregory S. Blank; David H. Reifsnyder

January 5, 1999

Effect of electric field on liquid chromatographic separation of peptide digests. Combining capillary separation techniques

Journal of Chromatography A, ISSN: 00219673

Alex Apffel; Hongfeng Yin; William S. Hancock; Douglass McManigill; John Frenz; Shiaw-Lin Wu

January 5, 1999

Treatment with growth hormone enhances contractile reserve and intracellular calcium transients in myocytes from rats with postinfarction heart failure

Circulation, ISSN: 00097322

Minori Tajima; Ellen O. Weinberg; Jozef Bartunek; Hongkui Jin; Renhui Yang; Nicholas F. Paoni; Beverly H. Lorell

January 5, 1999

Use of the steric mass action model in ion-exchange chromatographic process development

Journal of Chromatography A, ISSN: 00219673

Harish V. Iyer; Sarah Tapper; Philip M. Lester; Bradley Wolk; Robert Van Reis

January 4, 1999

Boo, a novel negative regulator of cell death, interacts with Apaf-1

EMBO Journal, ISSN: 02614189

Qizhong Song; Yongping Kuang; Vishva M. Dixit; Claudius Vincenz

January 1, 1999

Elastase substrate specificity tailored through substrate-assisted catalysis and phage display

Protein Engineering, ISSN: 02692139

William Dall'Acqua; Cornelia Halin; Maria L. Rodrigues; Paul J. Carter

January 1, 1999

Somatotroph and lactotroph changes in the adenohypophyses of mice with disrupted insulin-like growth factor I gene

Endocrinology, ISSN: 00137227

Lucia Stefaneanu; Powell-Braxton; Wesley B. Won; Varadaraj Chandrashekar; Andrzej Bartke

January 1, 1999

Analytical ultracentrifugation in the pharmaceutical industry

Journal of Pharmaceutical Sciences, ISSN: 00223549

Jun Liu; Steven J. Shire

January 1, 1999

Selective cloning of cell surface proteins involved in organ development: Epithelial glycoprotein is involved in normal epithelial differentiation

Endocrinology, ISSN: 00137227

Jean-Philippe Stephan; Penelope E. Roberts; Bald; James Lee; Qimin Gu; Devaux; Mather

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