Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 11801 - 11850 OF 15217 RESULTS

Effects of Igf1 gene deletion on postnatal growth patterns
Endocrinology, ISSN: 00137227
Jie Wang; Jian Zhou; Powell-Braxton; Carolyn Bondy
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Evidence that insulin-like growth factor I and growth hormone are required for prostate gland development
Endocrinology, ISSN: 00137227
Weifeng Ruan; Powell-Braxton; John J. Kopchick; David Kleinberg
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Estimating effectiveness in an observational study: A case study of dornase alfa in cystic fibrosis
Journal of Pediatrics, ISSN: 00223476
Charles A. Johnson; Butler; Michael W. Konstan; Timothy J. Breen; Morgan
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Capillary electrophoresis sodium dodecyl sulfate nongel sieving analysis of a therapeutic recombinant monoclonal antibody: A biotechnology perspective
Analytical Chemistry, ISSN: 00032700
Glenn Hunt; Wassim Nashabeh
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Heregulin enhances regenerative proliferation in postnatal rat utricular sensory epithelium after ototoxic damage
Journal of Neurocytology, ISSN: 03004864
Zheng; Gretchen D. Frantz; Lewis; Mark X. Sliwkowski; Gao
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VEGF antagonism reduces edema formation and tissue damage after ischemia/reperfusion injury in the mouse brain
Journal of Clinical Investigation, ISSN: 00219738
Nicholas Van Bruggen; Harold Thibodeaux; James T. Palmer; Wyne P. Lee; Ling Fu; Cairns; Daniel B. Tumas; Gerlai; Simon P. Williams; Menno Van Lookeren Campagne; Napoleone Ferrara
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Secondary reduction in the apparent diffusion coefficient of water, increase in cerebral blood volume, and delayed neuronal death after middle cerebral artery occlusion and early reperfusion in the rat
Journal of Cerebral Blood Flow and Metabolism, ISSN: 0271678X
Menno Van Lookeren Campagne; Roger Thomas; Harold Thibodeaux; James T. Palmer; Simon P. Williams; David G Lowe; Nicholas Van Bruggen
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Anti-IgE as novel therapy for the treatment of asthma
Current Opinion in Pulmonary Medicine, ISSN: 10705287
Robert B. Fick Jr.
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RIPs: An emerging family of kinases involved in pro-inflammatory and apoptotic signaling
Cold Spring Harbor Symposia on Quantitative Biology, ISSN: 00917451
Vishva M. Dixit
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Characterization of a candidate Borrella burgdorferi β3-chain integrin ligand identified using a phage display library
Molecular Microbiology, ISSN: 0950382X
Jenifer Coburn; Wambui Chege; Loranne Magoun; Bodary; John M. Leong
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Neuregulin receptor-mediated gene transfer by human epidermal growth factor receptor 2-targeted antibodies and neuregulin-1
Cancer Gene Therapy, ISSN: 09291903
Jeffrey Kern; Robert Wakita; Mark X. Sliwkowski
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Expression of the mucosal vascular addressin, MAdCAM-1, in inflammatory liver disease
Liver, ISSN: 01069543
Kenneth J. Hillan; Kelly E. Hagler; Roderick N. M. MacSween; Anne Ryan; Renz; Chiu; Rod K. Ferrier; George L. Bird; Amar P. Dhillon; Linda D. Ferrell; Sherman Fong
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Intraocular pharmacokinetics and safety of a humanized monoclonal antibody in rabbits after intravitreal administration of a solution or a PLGA microsphere formulation
Toxicological Sciences, ISSN: 10966080
Joyce Mordenti; Karen Thomsen; Vojtech Licko; Lea Berleau; Jeanne Kahn; R. Andrew Cuthbertson; Duenas; Anne Ryan; Cheryl A. Schofield; Terrence W. Berger; Meng; Cleland
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Comparisons of the Intraocular Tissue Distribution, Pharmacokinetics, and Safety of 125I-Labeled Full-Length and Fab Antibodies in Rhesus Monkeys Following Intravitreal Administration
Toxicologic Pathology, ISSN: 01926233
Joyce Mordenti; R. Andrew Cuthbertson; Napoleone Ferrara; Karen Thomsen; Lea Berleau; Vojtech Licko; Philip C. Allen; Celia R. Valverde; Meng; David T.W. Fei; Kathleen M. Fourre; Anne Ryan
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Hypertension and endothelial dysfunction in apolipoprotein E knockout mice
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN: 10795642
Renhui Yang; Powell-Braxton; Annie Ko Ogaoawara; Noel Dybdal; Bunting; Osamu Ohneda; Hongkui Jin
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A common mechanism for recombinant human NGF, BDNF, NT-3, and murine NGF slow unfolding
Protein Science, ISSN: 09618368
Linda R. De Young; Charles H. Schmelzer; Louis E. Burton
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Airway epithelial CFTR mRNA expression in cystic fibrosis patients after repetitive administration of a recombinant adenovirus
Journal of Clinical Investigation, ISSN: 00219738
Ben-Gary Harvey; Philip L. Leopold; Neil R. Hackett; Tina M. Grasso; P. Mickey Williams; Ayly Ling Tucker; Robert J. Kaner; Barbara Ferris; Gonda; Sweeney; Ramachandran Ramalingam; Kovesdi; Steven Shak; Crystal
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Creatine: a review of efficacy and safety.
Journal of the American Pharmaceutical Association (Washington,D.C. : 1996), ISSN: 10865802
Graham; Hatton
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Development of noradrenergic neurons in the zebrafish hindbrain requires BMP, FGF8, and the homeodomain protein soulless/Phox2a
Neuron, ISSN: 08966273
Guo; Brush; Hiroki Teraoka; Goddard; Stephen W. Wilson; Mary C. Mullins; Rosenthal
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Conformational changes in the activation loop of the insulin receptor's kinase domain
Protein Science, ISSN: 09618368
Mark Frankel; Steven M. Bishop; Ararat J. Ablooglu; Yuan-Ping Han; Ronald A. Kohanski
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Chromatography of recombinant proteins.
Developments in biological standardization, ISSN: 03015149
O'Connor
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Kinase Receptor Activation (KIRA): a rapid and accurate alternative to endpoint bioassays.
Developments in biological standardization, ISSN: 03015149
Michael D Sadick
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How much insulin-like growth factor-I (IGF-I) circulates?: impact of standardization on IGF-I assay accuracy.
Developments in biological standardization, ISSN: 03015149
Quarmby; Quan
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Pharmacokinetics of insulin-like growth factor I in hypopituitarism: Correlation with binding proteins
American Journal of Physiology - Endocrinology and Metabolism, ISSN: 01931849
Nelly Mauras; Quarmby; Duane C. Bloedow
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Role of baseline parameters in determining indirect pharmacodynamic responses
Journal of Pharmaceutical Sciences, ISSN: 00223549
Sun; William J. Jusko
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FGF-19, a novel fibroblast growth factor with unique specificity for FGFR4
Cytokine, ISSN: 10434666
Xie; Ilona N. Holcomb; Bethanne Deuel; Patrick Dowd; Arthur Huang; Alicia Vagts; Foster; Jie Liang; Brush; Qimin Gu; Kenneth J. Hillan; Goddard; Austin L. Gurney
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Allergic bronchopulmonary aspergillosis in cystic fibrosis: Reported prevalence, regional distribution, and patient characteristics
Chest, ISSN: 00123692
David E. Geller; Kaplowitz; Michael Light; Andrew A. Colin
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A human antibody that binds to the γ-carboxyglutamic acid domain of factor IX is a potent antithrombotic in vivo
Thrombosis and Haemostasis, ISSN: 03406245
Refino; Jacques Himber; Louis Burcklen; Paul Moran; Peek; Shelley Suggett; Devaux; Daniel Kirchhofer
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Role of vascular endothelial growth factor in the regulation of angiogenesis
Kidney International, ISSN: 00852538
Napoleone Ferrara
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A real time quantitative PCR-based method for the detection and quantification of simian virus 40
Biologicals, ISSN: 10451056
Shi; Jeniffer Ho; Lenore A Norling; Margaret Roy; Yuan Xu
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Real time quantitative PCR as a method to evaluate simian virus 40 removal during pharmaceutical protein purification
Biologicals, ISSN: 10451056
Shi; Lenore A Norling; Allen S.L. Lau; Sherrie Krejci; Alison J. Laney; Yuan Xu
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Functional roles for PECAM-1 (CD31) and VE-cadherin (CD144) in tube assembly and lumen formation in three-dimensional collagen gels
American Journal of Pathology, ISSN: 00029440
Suya Yang; Jennifer Graham; Jeanne Kahn; Eric A. Schwartz; Mary E. Gerritsen
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The biology of human epidermal growth factor receptor 2.
Current Oncology Reports, ISSN: 15233790
Sundaresan; Elicia M. Penuel; Mark X. Sliwkowski
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Development and testing of a thermoluminescence dosemeter for mixed neutron-photon-beta radiation fields
Radiation Protection Dosimetry, ISSN: 01448420
Zummo; Liu
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Inhibitory mechanism of the CXCR4 antagonist T22 against human immunodeficiency virus type 1 infection
Journal of Virology, ISSN: 0022538X
Tsutomu Murakami; Tian-Yuan Zhang; Yoshio Koyanagi; Yuetsu Tanaka; Jin Kim; Yoichi Suzuki; Shigeru Minoguchi; Hirokazu Tamamura; Michinori Waki; Akiyoshi Matsumoto; Nobutaka Fujii; Hisatoshi Shida; James A. Hoxie; Stephen C. Peiper; Naoki Yamamoto
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Commentary: Role of the pathologist in the identification and characterization of therapeutic molecules
Toxicologic Pathology, ISSN: 01926233
Anne Ryan
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Anatomic localization of 24- and 96-h particle retention in canine airways
Journal of Applied Physiology, ISSN: 87507587
Kreyling; Blanchard; Godleski; Haeussermann; Heyder; Hutzler; Schulz; Sweeney; Takenaka; Ziesenis
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Lyophilization of protein formulations in vials: Investigation of the relationship between resistance to vapor flow during primary drying and small-scale product collapse
Journal of Pharmaceutical Sciences, ISSN: 00223549
David E. Overcashier; Thomas W. Patapoff; Chung C. Hsu
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Correlation of CT findings with clinical evaluations in 261 patients with symptomatic bronchiectasis
American Journal of Roentgenology, ISSN: 0361803X
David A. Lynch; John Newell; Valerie Hale; Debra Dyer; Kevin Corkery; Fox; Patricia Gerend; Robert B. Fick Jr.
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Safety and antitumor activity of recombinant soluble Apo2 ligand
Journal of Clinical Investigation, ISSN: 00219738
Avi Ashkenazi; Roger Pai; Fong; Susan Leung; David Lawrence; Scot A. Marsters; Christine Blackie; Ling Chang; Amy E. McMurtrey; Andrea Hebert; Laura DeForge; Iphigenia Koumenis; Lewis; Louise A. Harris; Bussiere; Koeppen; Shahrokh; Ralph H. Schwall
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Triggering cell death: The crystal structure of Apo2L/TRAIL in a complex with death receptor 5
Molecular Cell, ISSN: 10972765
Sarah G. Hymowitz; Hans W. Christinger; Fuh; Ultsch; Mark P. O'Connell; Robert F. Kelley; Avi Ashkenazi; De Vos
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Probing intermolecular backbone H-bonding in serine proteinase-protein inhibitor complexes
Chemistry and Biology, ISSN: 10745521
Wuyuan Lu; Michael Randal; Anthony A. Kossiakoff; Stephen B. H. Kent
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Pharmacokinetics and pharmacodynamics of sibrafiban, an orally administered IIb/IIIa antagonist, in patients with acute coronary syndrome.
Journal of Clinical Pharmacology, ISSN: 00912700
Modi; Novotny; Reimann; Christopher P. Cannon; Braunwauld
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Depletion of eosinophils in mice through the use of antibodies specific for C-C chemokine receptor 3 (CCR3)
Journal of Leukocyte Biology, ISSN: 07415400
Grimaldi; Nai-Xuan Yu; Gabrielle Grunig; Brian W. P. Seymour; Françoise Cottrez; Douglas S. Robinson; Nancy Hosken; Walter G. Ferlin; Xiaoyan Wu; Hortensia Soto; Anne O'Garra; Maureen C. Howard; Coffman
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The effect of growth hormone treatment on stature in Aarskog syndrome
Journal of Pediatric Endocrinology and Metabolism, ISSN: 0334018X
Anna Petryk; Samuel Richten; Judy P. Sy; Sandra L. Blethen
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Transformation by v-Src: Ras-MAPK and PI3K-mTOR mediate parallel pathways
Molecular Biology of the Cell, ISSN: 10591524
Elicia M. Penuel; G. Steven Martin
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Hepatocyte growth factor inhibits amiloride-sensitive Na+ channel function in cystic fibrosis airway epithelium in vitro
Pulmonary Pharmacology and Therapeutics, ISSN: 10945539
Shen; Widdicombe; Mrsny
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A comparison of the national registry of myocardial infarction 2 with the cooperative cardiovascular project
Journal of the American College of Cardiology, ISSN: 07351097
Nathan R. Every; Paul D. Frederick; Michael Robinson; Jonathan Sugarman; Laura J. Bowlby; Hal V. Barron
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Safety assessment of single-bolus administration of TNK tissue- plasminogen activator in acute myocardial infarction: The ASSENT-1 trial
American Heart Journal, ISSN: 00028703
Frans Van De Werf; Christopher P. Cannon; Anne Luyten; Katrijn Houbracken; Carolyn H. McCabe; Berioli; Bluhmki; Hans Sarelin; Wang-Clow; Fox; Eugene Braunwald
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IgE inhibition as a therapy for allergic disease
International Archives of Allergy and Immunology, ISSN: 10182438
Paula Jardieu; Robert B. Fick Jr.
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