Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 11851 - 11900 OF 16124 RESULTS

A phase II study of thalidomide in advanced metastatic renal cell carcinoma
Investigational New Drugs, ISSN: 01676997
David R. Minor; Dana Monroe; Lisa A. Damico; Meng; Uma Suryadevara; Laurence Elias
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Phosphorylation and regulation of β-catenin by casein kinase Iε
Journal of Biochemistry, ISSN: 0021924X
Sakanaka
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Premenstrual dysphoric disorder is there an economic burden of Illness?
Medical Care, ISSN: 00257079
Chawla; Ralph Swindle; Stacey Long; Sean Kennedy; Barbara Sternfeld
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Solid–phase synthesis of dual α4β1#x03B1;4β7 integrin antagonists: Two scaffolds with overlapping pharmacophores
Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X
Georgette M. Castanedo; Fredrick C. Sailes; Dubree; John B. Nicholas; Lisa D. Caris; Clark; Keating; Beresini; Chiu; Fong; James C. Marsters Jr.; Jackson; Daniel P. Sutherlin
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Albumin affinity tags increase peptide half-life in vivo
Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X
Michael F. T. Koehler; Zobel; Beresini; Lisa D. Caris; Dan Combs; Paasch; Lazarus
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Solid–phase synthesis of dual α4β1#x03B1;4β7 integrin antagonists: Two scaffolds with overlapping pharmacophores
Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X
Georgette M. Castanedo; Fredrick C. Sailes; Dubree; John B. Nicholas; Lisa D. Caris; Clark; Keating; Beresini; Chiu; Sherman Fong; James C. Marsters Jr.; Jackson; Daniel P. Sutherlin
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Evaluation of HER-2/neu expression in prostatic adenocarcinoma: A request for a standardized, organ specific methodology
Cancer, ISSN: 0008543X
Katya M. Sanchez; Christopher J. Sweeney; Robert Mass; Michael O. Koch; George J. Eckert; William A. Geary; Lee Ann Baldridge; Shaobo Zhang; John N. Eble; Liang Cheng
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Distinct antigenic features of linear epitopes at the N-terminus and C-terminus of 65 kDa glutamic acid decarboxylase (GAD65): Implications for autoantigen modification during pathogenesis
Clinical and Experimental Immunology, ISSN: 00099104
Al-Bukhari; Radford; Bouras; Davenport; Trigwell; Bottazzo; Lai; Schwartz; Tighe; Todd
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Inhibition of ligand-mediated HER2 activation in androgen-independent prostate cancer
Cancer Research, ISSN: 00085472
Nerissa Mendoza; Gail L. Phillips; Johnny Silva; Ralph H. Schwall; Dineli Wickramasinghe
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Suppression of antibody production by TNF-related apoptosis-inducing ligand (TRAIL)
Cellular Immunology, ISSN: 00088749
Nobuhiko Kayagaki; Noriko Yamaguchi; Masaaki Abe; Sachiko Hirose; Toshikazu Shirai; Ko Okumura; Hideo Yagita
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VEGF and the quest for tumour angiogenesis factors
Nature Reviews Cancer, ISSN: 1474175X
Napoleone Ferrara
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Zmpste24 deficiency in mice causes spontaneous bone fractures, muscle weakness, and a prelamin A processing defect
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Martin O. Bergo; Bryant Gavino; Ross; Walter K. Schmidt; Christine Hong; Lonnie V. Kendall; Andreas Mohr; Margarita Meta; Harry Genant; Yebin Jiang; Erik R. Wisner; Nicholas Van Bruggen; Richard A. D. Carano; Susan Michaelis; Stephen M. Griffey; Stephen G. Young
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BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-κB2
Immunity, ISSN: 10747613
Nobuhiko Kayagaki; Minhong Yan; Dhaya Seshasayee; Hua Wang; Wyne P. Lee; French; Iqbal S. Grewal; Andrea G Cochran; Nathaniel C. Gordon; Jianping Yin; Melissa A. Starovasnik; Vishva M. Dixit
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The pharmacokinetic and pharmacodynamic characteristics of a long-acting growth hormone (GH) preparation (Nutropin Depot) in GH-deficient adults
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X
David Cook; Beverly M. K. Biller; Mary Lee Vance; Andrew R. Hoffman; Lawrence S. Phillips; Kathleen M. Ford; Benziger; Illeperuma; Sandra L. Blethen; Kenneth M. Attie; Dao; Reimann; Fielder
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Initial clinical results of tenecteplase (TNK) in catheter-directed thrombolytic therapy
Journal of Endovascular Therapy, ISSN: 15266028
Mahmood K Razavi; Humberto Wong; Stephen T. Kee; Daniel Y. Sze; Charles P. Semba; Michael D. Dake
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Albumin binding as a general strategy for improving the pharmacokinetics of proteins
Journal of Biological Chemistry, ISSN: 00219258
Dennis; Min Zhang; Meng; Miryam Kadkhodayan; Daniel Kirchhofer; Dan Combs; Lisa A. Damico
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Dissecting the oncogenic potential of Gli2: Deletion of an NH2-terminal fragment alters skin tumor phenotype
Cancer Research, ISSN: 00085472
Hong Sheng; Sara Goich; Aiqin Wang; Marina Grachtchouk; Lori Lowe; Rong Mo; Kui Lin; Frederic J. De Sauvage; Hiroshi Sasaki; Chi-chung Hui; Andrzej A. Dlugosz
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Theoretical and experimental investigation of the effect of proton transfer on the 27AI MAS NMR line shapes of zeolite-adsorbate complexes: An independent measure of solid acid strength
Journal of the American Chemical Society, ISSN: 00027863
Justin O. Ehresmann; Wei Wang; Bruno Herreros; Donat-Pierre Luigi; Venkatraman; Weiguo Song; John B. Nicholas; James F. Haw
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Molecular forms of NGF in human and rat neuropathic tissues: Decreased NGF precursor-like immunoreactivity in human diabetic skin
Journal of the Peripheral Nervous System, ISSN: 10859489
Yiangos Yiangou; Paul Facer; Sinicropi; Timothy J. Boucher; David L. H. Bennett; McMahon; Anand
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Proteomics in mixtures: Study results of ABRF-PRG02
Journal of Biomolecular Techniques, ISSN: 15240215 19434731
David Arnott; Mary Ann Gawinowicz; Raymond A. Grant; William Lane; Len C. Packman; Kaye D. Speicher; Kathryn Stone
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Challenging artificial genetic systems: Thymidine analogs with 5-position sulfur functionality
Nucleic Acids Research, ISSN: 03051048
Heike A. Held; Steven A. Benner
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Stanniocalcin 1 alters muscle and bone structure and function in transgenic mice
Endocrinology, ISSN: 00137227
Ellen H. Filvaroff; Guillet; Constance Zlot; Bao; Gladys S. Ingle; Hope Steinmetz; Hoeffel; Bunting; Ross; Richard A. D. Carano; Powell-Braxton; Graham F. Wagner; Eckert; Mary E. Gerritsen; French
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Effect of glycine on pH changes and protein stability during freeze-thawing in phosphate buffer systems
Journal of Pharmaceutical Sciences, ISSN: 00223549
Katherine A. Pikal-Cleland; Cleland; Thomas J. Anchordoquy; John F. Carpenter
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Endocrine gland-derived VEGF and the emerging hypothesis of organ-specific regulation of angiogenesis
Nature Medicine, ISSN: 10788956
Jennifer Lecouter; Rui Lin; Napoleone Ferrara
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The relationship of intracoronary stent placement following thrombolytic therapy to tissue level perfusion
Journal of Thrombosis and Thrombolysis, ISSN: 09295305
C.Michael Gibson; Frisch; Sabina A. Murphy; Steven G. Gourlay; Raymond J. Gibbons; Kenneth W. Baran; Michel Nguyen; Sebastian T. Palmeri; Hal V. Barron
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Efficient gene transduction to cultured hepatocytes by HIV-1 derived lentiviral vector
Transplantation Proceedings, ISSN: 00411345
Ohashi; Park; Ralph H. Schwall; Kay
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Sustained delivery of human growth hormone from a novel gel system: SABER™
Biomaterials, ISSN: 01429612
Okumu; Dao; Fielder; Noel Dybdal; Brooks; Samir Sane; Cleland
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Performance of a novel Viresolve NFR virus filter
Biotechnology Progress, ISSN: 87567938
Helene Brough; Chris Antoniou; Jeffrey Carter; Jocelyn Jakubik; Yuan Xu; Herbert Lutz
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Determination of residual moisture in lyophilized protein pharmaceuticals using a rapid and non-invasive method: Near infrared spectroscopy
PDA Journal of Pharmaceutical Science and Technology, ISSN: 10797440
Tanya P. Lin; Chung C. Hsu
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A target-mediated model to describe the pharmacokinetics and hemodynamic effects of recombinant human vascular endothelial growth factor in humans
Clinical Pharmacology and Therapeutics, ISSN: 00099236
Stephen M. Eppler; Dan Combs; Timothy D. Henry; John J. Lopez; Stephen G. Ellis; Joo-Hee Yi; Brian H. Annex; Edward R. McCluskey; Zioncheck
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Identification of a region within the ErbB2/HER2 intracellular domain that is necessary for ligand-independent association
Journal of Biological Chemistry, ISSN: 00219258
Elicia M. Penuel; Robert W. Akita; Mark X. Sliwkowski
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A direct role of the homeodomain proteins Phox2a/2b in noradrenaline neurotransmitter identity determination
Journal of Neurochemistry, ISSN: 00223042
Hyemyung Seo; Seok Jong Hong; Guo; Hee-Sun Kim; Chun-Hyung Kim; Dong-Youn Hwang; Ole Isacson; Rosenthal; Kwang-Soo Kim
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Amisyn, a novel syntaxin-binding protein that may regulate SNARE complex assembly
Journal of Biological Chemistry, ISSN: 00219258
Suzie J. Scales; Boris A. Hesser; Esteban S. Masuda; Richard H. Scheller
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Selective α4β7 integrin antagonists and their potential as antiinflammatory agents
Journal of Medicinal Chemistry, ISSN: 00222623
Dubree; Dean R. Artis; Georgette M. Castanedo; James C. Marsters Jr.; Daniel P. Sutherlin; Lisa D. Caris; Clark; Keating; Beresini; Chiu; Fong; Henry B. Lowman; Nicholas J. Skelton; Jackson
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Selective α4β7 integrin antagonists and their potential as antiinflammatory agents
Journal of Medicinal Chemistry, ISSN: 00222623
Dubree; Dean R. Artis; Georgette M. Castanedo; James C. Marsters Jr.; Daniel P. Sutherlin; Lisa D. Caris; Clark; Keating; Beresini; Chiu; Sherman Fong; Henry B. Lowman; Nicholas J. Skelton; Jackson
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Lack of fucose on human IgG1 N-linked oligosaccharide improves binding to human FcγRIII and antibody-dependent cellular toxicity
Journal of Biological Chemistry, ISSN: 00219258
Robert L. Shields; Lai; Rodney Keck; O'Connell; Kyu Hong; Meng; Weikert; Presta
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Vascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnover
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
John Street; Bao; Leo Deguzman; Bunting; Franklin V. Peale Jr.; Napoleone Ferrara; Hope Steinmetz; Hoeffel; Cleland; Daugherty; Nicholas Van Bruggen; H. Paul Redmond; Richard A. D. Carano; Ellen H. Filvaroff
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Casein kinase 1: A Wnt'er of disconnect
Current Biology, ISSN: 09609822
Paul G. Polakis
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Truncated, inactive N-acetylglucosaminyltransferase III (GlcNAc-TIII) induces neurological and other traits absent in mice that lack GlcNAc-TIII
Journal of Biological Chemistry, ISSN: 00219258
Riddhi Bhattacharyya; Mantu Bhaumik; T. Shantha Raju; Pamela Stanley
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Effects on quality of life of combined trastuzumab and chemotherapy in women with metastatic breast cancer
Journal of Clinical Oncology, ISSN: 0732183X
David Osoba; Dennis J. Slamon; Michael Burchmore; Maureen Murphy
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Three-dimensional structure of the amino-terminal domain of syntaxin 6, a SNAP-25 C homolog
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Kira M. S. Misura; Jason Bock; Lino C. Gonzalez Jr.; Richard H. Scheller; William I. Weis
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Regulation of endothelial cell proliferation and apoptosis by cyclic pressure
Annals of Biomedical Engineering, ISSN: 00906964
Hainsworth Y. Shin; Mary E. Gerritsen; Rena Bizios
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A risk model derived from the National Registry of Myocardial Infarction 2 database for predicting mortality after coronary artery bypass grafting during acute myocardial infarction
American Journal of Cardiology, ISSN: 00029149
Jonathan G Zaroff; Dante G DiTommaso; Hal V. Barron
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Synthesis of the heptamethylbenzenium cation in zeolite-β: In situ NMR and theory
Catalysis Letters, ISSN: 1011372X
Weiguo Song; John B. Nicholas; Alain Sassi; James F. Haw
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Validation of large-scale chromatographic processes, Part 2: Results from the case study of neuleze capture on Macroprep High-S
BioPharm, ISSN: 10408304
Timothy N. Breece; Ellen Gilkerson; Charles H. Schmelzer
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Quantitative evaluation of proteins in one- and two-dimensional polyacrylamide gels using a fluorescent stain
Electrophoresis, ISSN: 01730835
Julie C. Nishihara; Kathleen M. Champion
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VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism
Nature, ISSN: 00280836
Hans-Peter Gerber; Ajay K. Malik; Gregg Solar; Sherman; Xiao Huan Liang; Meng; Kyu Hong; James C. Marsters Jr.; Napoleone Ferrara
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KDR (VEGF receptor 2) is the major mediator for the hypotensive effect of VEGF
Hypertension, ISSN: 0194911X
Bing Li; Annie Ogasawara; Renhui Yang; Wei Wei; Guo-Wei He; Zioncheck; Bunting; De Vos; Hongkui Jin
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Alpha 4 integrin antagonists
Current Pharmaceutical Design, ISSN: 13816128
Jackson
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Structure, function, and activation of coagulation factor VII
Current Protein and Peptide Science, ISSN: 13892037
Eigenbrot
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