Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 11901 - 11950 OF 15566 RESULTS

January 1, 2000

Ligand-binding sites in Ig-like domains of receptor tyrosine kinases

Journal of Molecular Medicine, ISSN: 09462716

Wiesmann; Yves A. Muller; De Vos

January 1, 2000

The impact of recombinant human growth hormone treatment during chronic renal insufficiency on renal transplant recipients

Journal of Pediatrics, ISSN: 00223476

Richard N. Fine; E. Kenneth Sullivan; Joyce Kuntze; Sandra L. Blethen; Edward C. Kohaut

January 1, 2000

Choice of microcentrifuge tubes influences T cell proliferation assay

BioTechniques, ISSN: 07366205

Wei; Mrsny; Blumberg; Fried; Andreas D. Christ

January 1, 2000

New approaches to antigen delivery

Critical Reviews in Therapeutic Drug Carrier Systems, ISSN: 07434863

David FitzGerald; Mrsny

January 1, 2000

Identification of a receptor for BLyS demonstrates a crucial role in humoral immunity

Nature Immunology, ISSN: 15292908

Minhong Yan; Scot A. Marsters; Iqbal S. Grewal; Hua Wang; Avi Ashkenazi; Vishva M. Dixit

January 1, 2000

Endothelial dysfunction, hemodynamic forces, and atherogenesis

Annals of the New York Academy of Sciences, ISSN: 00778923

Gimbrone Jr.; James N. Topper; Tobi Nagel; Keith R. Anderson; Guillermo Garcia-Cardeña

January 1, 2000

Mobilization of vitamin A stores in rats after administration of 2,3,7,8-tetrachlorodibenzo-p-dioxin: A kinetic analysis

Toxicological Sciences, ISSN: 10966080

Sean K. Kelley; Charlotte B. Nilsson; Michael H. Green; Joanne Balmer Green; Helen Håkansson

January 1, 2000

Measurement of the acid-labile subunit of the insulin-like growth factor binding protein complex in human serum: A comparison of four immunoassays

Journal of Endocrinology, ISSN: 00220795

Baxter; Svejkar; Khosravi; Bennett; Hardman; Senese; Mistry; Walton; Quarmby

January 1, 2000

Can retinoic acid ameliorate the physiologic and morphologic effects of elastase instillation in the rat?

Chest, ISSN: 00123692

Tepper; Juergen Pfeifer; Melinda C. Aldrich; Daniel B. Tumas; Jeffrey Kern; Eric Hoffman; Geoffrey McLennan; Dallas M. Hyde

January 1, 2000

Stimulation of osteoclast differentiation in vitro by mouse oncostatin M, leukaemia inhibitory factor, cardiotrophin-1 and interleukin 6: Synergy with dexamethasone

Cytokine, ISSN: 10434666

Richards; Langdon; Paula Deschamps; Diane Pennica; Stephen G. Shaughnessy

January 1, 2000

Thrombopoietin in the thrombocytopenic term and preterm newborn

Pediatrics, ISSN: 00314005

Timothy S. E. Albert; Meng; Paul Simms; Robert L. Cohen; Roderic H. Phibbs

January 1, 2000

Mutational analysis of the major coat protein of M13 identifies residues that control protein display

Protein Science, ISSN: 09618368

Gregory A. Weiss; James A. Wells; Sachdev S. Sidhu

January 1, 2000

Species-specific variation in glycosylation of Igc: Evidence for the species-specific sialylation and branch-specific galactosylation and importance for engineering recombinant glycoprotein therapeutics

Glycobiology, ISSN: 09596658

T. Shantha Raju; Briggs; Steve M. Borge; Andrew J.S. Jones

January 1, 2000

Integrin αIIbβ3 and ανβ3 inhibition reduces neointima after porcine coronary angioplasty

Heart, ISSN: 13556037

Chico; Gunn; Arnold; Sherron L. Bullens; Michael T. Lipari; Bunting; Cumberland; Crossman

January 1, 2000

Uncoupling protein homologs: Emerging views of physiological function

Journal of Nutrition, ISSN: 00223166

Adams

January 1, 2000

Alteplase as an alternative to urokinase

Journal of Vascular and Interventional Radiology, ISSN: 10510443

Charles P. Semba; Curtis W. Bakal; Karim A. Calis; Gerald E. Grubbs; David W. Hunter; Terence A. S. Matalon; Timothy P. Murphy; David Stump; Steven Thomas; David L. Warner

January 1, 2000

The rtPA (Alteplase) 0- to 6-hour acute stroke trial, part A (A0276g): Results of a double-blind, placebo-controlled, multicenter study

Stroke, ISSN: 00392499

Wayne M. Clark; Gregory W. Albers; Kenneth Madden; Scott Hamilton

January 1, 2000

Use of rhDNase therapy and costs of respiratory-related care in patients with cystic fibrosis

Annals of Pharmacotherapy, ISSN: 10600280

Daniel A. Ollendorf; Lisa J. McGarry; Marc Watrous; Gerry Oster

January 1, 2000

Recombination events between the p47-phox gene and its highly homologous pseudogenes are the main cause of autosomal recessive chronic granulomatous disease

Blood, ISSN: 00064971

Joachim Roesler; John T. Curnutte; Julie Rae; David Barrett; Pablo Patino; Stephen J. Chanock; Agnes Goerlach

January 1, 2000

Genomic structure of the human p47-phox (NCF1) gene

Blood Cells, Molecules, and Diseases, ISSN: 10799796

Stephen J. Chanock; Joachim Roesler; Shixing Zhan; Penelope J. Hopkins; Pauline L. Lee; David Barrett; Barbara Christensen; John T. Curnutte; Agnes Görlach

January 1, 2000

Body mass index (BMI) in Turner syndrome before and during growth hormone (GH) therapy

International Journal of Obesity, ISSN: 03070565

Blackett; Amy Chen Rundle; James W. Frane; Sandra L. Blethen

January 1, 2000

Effects of administration of a single dose of a humanized monoclonal antibody to CD11a on the immunobiology and clinical activity of psoriasis

Journal of the American Academy of Dermatology, ISSN: 01909622

Alice Gottlieb; James G. Krueger; Ross Bright; Mark Ling; Mark Lebwohl; Sewon Kang; Steve Feldman; Mary Spellman; Knut Wittkowski; Hans D. Ochs; Paula Jardieu; Bauer; Mark White; Russell L Dedrick; Marvin Garovoy

January 1, 2000

Induction of an angiogenic phenotype in endometriotic stromal cell cultures by interleukin-1β

Molecular Human Reproduction, ISSN: 13609947

Dan I. Lebovic; Frauke Bentzien; Victor A. Chao; Evelyn N. Garrett; Meng; Robert N. Taylor

January 1, 2000

Validation of excised bovine nasal mucosa as in vitro model to study drug transport and metabolic pathways in nasal epithelium

Journal of Pharmaceutical Sciences, ISSN: 00223549

M. Christiane Schmidt; Daniel Simmen; Monika Hilbe; Peter Boderke; Günter Ditzinger; Jürgen Sandow; Steffen Lang; Rubas; Hans P. Merkle

January 1, 2000

Fast probabilistic analysis of sequence function using scoring matrices

Bioinformatics, ISSN: 13674803

Thomas D Wu; Craig G. Nevill-Manning; Douglas L. Brutlag

January 1, 2000

Mammalian-cell-produced neurturin (NTN) is more potent than purified Escherichia coli-produced NTN

Experimental Neurology, ISSN: 00144886

Michael R. Hoane; Kamal D. Puri; Lei Xu; Paul F. Stabila; Hongmei Zhao; Amit G. Gulwadi; Phillips; Devaux; Mark D. Lindner; Weng Tao

January 1, 2000

Estimation in a Cox proportional hazards cure model

Biometrics, ISSN: 0006341X

Sy; Jeremy M.G. Taylor

January 1, 2000

Identification and regulation of receptor tyrosine kinases Rse and Mer and their ligand Gas6 in testicular somatic cells

Journal of Andrology, ISSN: 01963635

Michael C. W. Chan; Mather; Glynis McCray; Will M. Lee

January 1, 2000

Use of phage display for the generation of human antibodies that neutralize factor IXa function

Blood Coagulation and Fibrinolysis, ISSN: 09575235

Shelley Suggett; Daniel Kirchhofer; Hass; Michael T. Lipari; Paul Moran; Nagel; Judice; Kurt A. Schroeder; Jeffrey Tom; Henry B. Lowman; Adams; Dan L. Eaton; Devaux

January 1, 2000

Substrate-assisted catalysis: Molecular basis and biological significance

Protein Science, ISSN: 09618368

William Dall'Acqua; Paul J. Carter

January 1, 2000

Web Alert. Apoptosis.

Chemistry and Biology, ISSN: 10745521

Eric W. Humke

January 1, 2000

WECHE: A novel hematopoietic regulatory factor

Immunity, ISSN: 10747613

Osamu Ohneda; Kinuko Ohneda; Hisayuki Nomiyama; Zhong Zheng; Steven A. Gold; Fumio Arai; Takeshi Miyamoto; Bruce E. Taillon; Richard A. McIndoe; Richard A. Shimkets; Lewin; Toshio Suda; Lasky

January 1, 2000

Targeting genes and proteins in the analysis of learning and memory: Caveats and future directions

Reviews in the Neurosciences, ISSN: 03341763

Gerlai

January 1, 2000

Putting the pieces together: contribution of fluorescence polarization assays to small molecule lead optimization

Proceedings of SPIE - The International Society for Optical Engineering, ISSN: 0277786X

Keating; James C. Marsters Jr.; Beresini; Ladner; Kimberly Zioncheck; Clark; Arellano; Bodary

January 1, 2000

The 2.0 Å structure of bovine interferon-γ; assessment of the structural differences between species

Acta Crystallographica Section D: Biological Crystallography, ISSN: 09074449

Michael Randal; Anthony A. Kossiakoff

January 1, 2000

The glial cell line-derived neurotrophic factor family receptor components are differentially regulated within sensory neurons after nerve injury

Journal of Neuroscience, ISSN: 02706474

David L. H. Bennett; Timothy J. Boucher; Armanini; Kris Poulsen; Gregory J. Michael; John V. Priestley; Phillips; McMahon; David L. Shelton

January 1, 2000

The importance of growth hormone replacement therapy for bone mass in young adults with growth hormone deficiency

Journal of Pediatric Endocrinology and Metabolism, ISSN: 0334018X

Kenneth M. Attie

January 1, 2000

A reversed-phase HPLC assay for plasminogen activators

Journal of Liquid Chromatography and Related Technologies, ISSN: 10826076

Yuan Xu; Cacia

January 1, 2000

APO2L/TRAIL expression in human brain tumors

Acta Neuropathologica, ISSN: 00016322

Mitsutoshi Nakamura; Johannes Rieger; Michael Weller; Jin Kim; Paul Kleihues; Hiroko Ohgaki

January 1, 2000

Growth hormone safety update from the National Cooperative Growth Study

Journal of Pediatric Endocrinology and Metabolism, ISSN: 0334018X

Thomas J. Maneatis; Joyce Baptista; Connelly; Sandra L. Blethen

January 1, 2000

Role of the distal half of the c-Mpl intracellular domain in control of platelet production by thrombopoietin in vivo

Molecular and Cellular Biology, ISSN: 02707306

Shiuh-Ming Luoh; Stefanich; Gregg Solar; Hope Steinmetz; Michael T. Lipari; Tamara I. Pestina; Carl W. Jackson; Frederic J. De Sauvage

January 1, 2000

Concomitant over-expression of vascular endothelial growth factor and its receptors in pancreatic cancer

International Journal of Cancer, ISSN: 00207136

Jun Itakura; Toshiyuki Ishiwata; Shen; Marko Kornmann; Murray Korc

January 1, 2000

Analysis of PTCH/SMO/SHH pathway genes in medulloblastoma

Genes Chromosomes and Cancer, ISSN: 10452257

Russell H. Zurawel; Cory Allen; Sharon Chiappa; Walter Cato; Jaclyn Biegel; Philip Cogen; Frederic J. De Sauvage; Corey Raffel

January 1, 2000

Angiography of fluoresceinated anti-vascular endothelial growth factor antibody and dextrans in experimental choroidal neovascularization

Archives of Ophthalmology, ISSN: 00039950

Michael J. Tolentino; Deeba Husain; Panagiotis Theodosiadis; Evangelos S. Gragoudas; Edward Connolly; Jeanne Kahn; Cleland; Anthony P. Adamis; R. Andrew Cuthbertson; Joan W. Miller

January 1, 2000

The seven-transmembrane receptor Smoothened cell-autonomously induces multiple ventral cell types

Nature Neuroscience, ISSN: 10976256

Mary Hynes; Weilan Ye; Kevin Wang; Donna Stone; Maximilien Murone; Frederic J. De Sauvage; Rosenthal

January 1, 2000

The nucleoskeleton: Go EAST, young man

Nature Cell Biology, ISSN: 14657392

Lasky

January 1, 2000

Clonidine for smoking cessation.

Cochrane database of systematic reviews (Online : Update Software), ISSN: 1469493X

Steven G. Gourlay; Stead; Neal L. Benowitz

January 1, 2000

Gene expression profiling in an in vitro model of angiogenesis

American Journal of Pathology, ISSN: 00029440

Jeanne Kahn; Fuad Mehraban; Gladys S. Ingle; Xiaohua Xin; Juliet E. Bryant; Gordon A. Vehar; Schoenfeld; Grimaldi; Franklin V. Peale Jr.; Aparna Draksharapu; Lewin; Mary E. Gerritsen

January 1, 2000

Toll-like receptor 2-mediated NF-κB activation requires a Rac I-dependent pathway

Nature Immunology, ISSN: 15292908

Laurence Arbibe; Jean-Paul Mira; Nicole Teusch; Lois Kline; Mausumee Guha; Nigel Mackman; Godowski; Richard J. Ulevitch; Ulla G. Knaus

January 1, 2000

Pharmacokinetics and pharmacodynamics of tenecteplase: Results from a phase II study in patients with acute myocardial infarction

Journal of Clinical Pharmacology, ISSN: 00912700

Modi; Fox; Fong-Wong Clow; Tanswell; Christopher P. Cannon; Frans Van De Werf; Eugene Braunwald

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