Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 1151 - 1200 OF 15414 RESULTS

Coming of Age: Human Genomics and the Cancer–Immune Set Point
Cancer immunology research, ISSN: 23266074 23266066
Christian Hammer; Ira Mellman
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Correlation of Optical Coherence Tomography Angiography of Type 3 Macular Neovascularization With Corresponding Histology
JAMA Ophthalmology, ISSN: 21686173 21686165
Andreas Berlin; Diogo Cabral; Ling Chen; Jeffrey D. Messinger; Chandrakumar Balaratnasingam; Randev Mendis; Daniela Ferrara; K. Bailey Freund; Christine A. Curcio
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Allelic variation in HLA-DRB1 is associated with development of antidrug antibodies in cancer patients treated with atezolizumab that are neutralizing in vitro
Clinical and Translational Science, ISSN: 17528062 17528054
Christian Hammer; Jane Ruppel; Lynn Kamen; Julie Hunkapiller; Ira Mellman; Quarmby
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Massively parallel phenotyping of coding variants in cancer with Perturb-seq
Nature Biotechnology, ISSN: 15461696 10870156
Oana Ursu; James T. Neal; Emily Shea; Pratiksha I. Thakore; Livnat Jerby-Arnon; Lan Nguyen; Danielle Dionne; Celeste Diaz; Julia Bauman; Mariam Mounir Mosaad; Christian Fagre; April Lo; Maria McSharry; Andrew O. Giacomelli; Seav Huong Ly; Orit Rozenblatt-Rosen; William C. Hahn; Andrew J. Aguirre; Alice H. Berger; Aviv Regev; Jesse S. Boehm
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INVESTIGATION OF THE USE OF SERUM BIOMARKERS FOR THE DETECTION OF CARDIAC DISEASE IN MARINE MAMMALS
Journal of Zoo and Wildlife Medicine, ISSN: 10427260
Melissa J. Joblon; Jennifer E. Flower; Laura A. Thompson; Kathleen Biddle; Deborah A. Burt; Tanja S. Zabka; Michael J. Adkesson; Barbie Halaska; Caroline E. C. Goertz; Natalie Rouse; Sion N. Cahoon; Kristen Jetzke; Richard Giovanelli; Allison D. Tuttle
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Assessment of Clinical Response Following Atezolizumab and Bevacizumab Treatment in Patients With Neuroendocrine Tumors A Nonrandomized Clinical Trial
JAMA Oncology, ISSN: 23742445 23742437
Daniel M. Halperin; Suyu Liu; Arvind Dasari; David Fogelman; Priya Bhosale; Armeen Mahvash; Jeannelyn S. Estrella; Laura Rubin; Ajaykumar C. Morani; Mark Knafl; Tim A. Overeem; Szu-Chin Fu; Luisa M. Solis; Edwin R. Parra Cuentas; Anuj Verma; Honglei Chen; Swati Gite; Priya Subashchandrabose; Shannon Dervin; Katja Schulze; Darbonne; Cindy Yun; Ignacio I. Wistuba; P. Andrew Futreal; Scott E. Woodman; James C. Yao
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Molecular classification of hormone-sensitive and castration-resistant prostate cancer, using nonnegative matrix factorization molecular subtyping of primary and metastatic specimens
Prostate, ISSN: 10970045 02704137
Kobe Yuen; Ben Tran; Angelyn Anton; Habib Hamidi; Anthony J. Costello; Niall M. Corcoran; Nathan Lawrentschuk; Natalie Rainey; Marie C. G. Semira; Peter Gibbs; Sanjeev Mariathasan; Shahneen Sandhu; Edward E. Kadel III
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Theragnostic significance of tumor-infiltrating lymphocytes and Ki67 in BRAFV600-mutant metastatic melanoma (BRIM-3 trial)
Current Problems in Cancer, ISSN: 01470272
Paul B. Googe; Stamatios Theocharis; Alexandros Pergaris; Haocheng Li; Yibing Yan; Edward McKenna; Stergios J. Moschos
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Assessment of Clinical Response Following Atezolizumab and Bevacizumab Treatment in Patients With Neuroendocrine Tumors A Nonrandomized Clinical Trial
JAMA Oncology, ISSN: 23742445 23742437
Daniel M. Halperin; Suyu Liu; Arvind Dasari; David Fogelman; Priya Bhosale; Armeen Mahvash; Jeannelyn S. Estrella; Laura Rubin; Ajaykumar C. Morani; Mark Knafl; Tim A. Overeem; Szu-Chin Fu; Luisa M. Solis; Edwin R. Parra Cuentas; Anuj Verma; Hong-Lei Chen; Swati Gite; Priya Subashchandrabose; Shannon Dervin; Katja Schulze; Darbonne; Cindy Yun; Ignacio I. Wistuba; P. Andrew Futreal; Scott E. Woodman; James C. Yao
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Fostering a diverse regional community of physician-scientist trainees
Journal of the National Medical Association, ISSN: 19434693 00279684
Mark E. Pepin; J. Paige Souder; Alice N. Weaver; Robin G. Lorenz; Talene Yacoubian; Randy L. Seay
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Endoplasmic reticulum stress activates human IRE1α through reversible assembly of inactive dimers into small oligomers
eLife, ISSN: 2050084X
Vladislav Belyy; Iratxe Zuazo-Gaztelu; Andrew Alamban; Avi Ashkenazi; Peter Walter
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Absorption, Distribution, Metabolism, and Excretion of Therapeutic Proteins: Current Industry Practices and Future Perspectives
Drug Metabolism and Disposition, ISSN: 1521009X 00909556
Jayaprakasam Bolleddula; Kevin Brady; Gerard Bruin; Anthony J. Lee; Jennifer A. Martin; Markus Walles; Keyang Xu; Tong-Yuan Yang; Xiaochun Zhu; Hongbin Yu
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A Cross Company Perspective on the Assessment of Therapeutic Protein Biotransformation
Drug Metabolism and Disposition, ISSN: 1521009X 00909556
Markus Walles; Michael Berna; Wenying Jian; Simon Hauri; Shawna Hengel; Lloyd King; John C. Tran; Cong Wei; Keyang Xu; Xiaochun Zhu
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Degrader-antibody conjugates
Chemical Society Reviews, ISSN: 14604744
Peter Dragovich
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Establishment of baseline profiles of 50 bile acids in preclinical toxicity species: A comprehensive assessment of translational differences and study design considerations for biomarker development
Toxicology and Applied Pharmacology, ISSN: 10960333 0041008X
Dewakar Sangaraju; Paula Katavolos; Xiaorong Liang; Carolina Chou; Tanja S. Zabka; Brian J. Dean; Jonathan M. Maher
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Establishment of baseline profiles of 50 bile acids in preclinical toxicity species: A comprehensive assessment of translational differences and study design considerations for biomarker development
Toxicology and Applied Pharmacology, ISSN: 0041008X
Dewakar Sangaraju; Paula Katavolos; Xiaorong Liang; Carolina Chou; Tanja S. Zabka; Brian J. Dean; Jonathan M. Maher
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Challenges in the structure determination of a dimeric impurity found during development of GDC-0326
Journal of Pharmaceutical and Biomedical Analysis, ISSN: 07317085
Nathaniel Segraves; Stefan G. Koenig; Jeffrey Stults; Shengli Ma; Antonio G. DiPasquale; Sarah J. Robinson; David J. Russell
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Challenges in the structure determination of a dimeric impurity found during development of GDC-0326
Journal of Pharmaceutical and Biomedical Analysis, ISSN: 1873264X 07317085
Nathaniel Segraves; Stefan G. Koenig; Jeffrey Stults; Shengli Ma; Antonio G. DiPasquale; Sarah J. Robinson; David J. Russell
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Degrader-antibody conjugates
Chemical Society Reviews, ISSN: 14604744 03060012
Peter Dragovich
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Evaluating human genetic support for hypothesized metabolic disease genes
Cell Metabolism, ISSN: 19327420 15504131
Peter Dornbos; Preeti Singh; Dong-Keun Jang; Anubha Mahajan; Sudha B. Biddinger; Jerome I Rotter; Mark I. McCarthy; Jason Flannick
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A saturation mutagenesis screen uncovers resistant and sensitizing secondary KRAS mutations to clinical KRASG12C inhibitors
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 10916490
Siyu Feng; Marinella G. Callow; Jean-Philippe Fortin; Zia Khan; David Bray; Michael Costa; Zhen Shi; Weiru Wang; Marie Evangelista
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A saturation mutagenesis screen uncovers resistant and sensitizing secondary KRAS mutations to clinical KRASG12C inhibitors
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 10916490 00278424
Siyu Feng; Marinella G. Callow; Jean-Philippe Fortin; Zia Khan; David Bray; Michael Costa; Shi; Weiru Wang; Marie Evangelista
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A saturation mutagenesis screen uncovers resistant and sensitizing secondary KRAS mutations to clinical KRASG12C inhibitors
Proceedings of the National Academy of Sciences of the United States of America,
Siyu Feng; Marinella G. Callow; Jean-Philippe Fortin; Zia Khan; David Bray; Michael Costa; Zhen Shi; Weiru Wang; Marie Evangelista
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High-efficiency nonviral CRISPR/Cas9-mediated gene editing of human T cells using plasmid donor DNA
Journal of Experimental Medicine, ISSN: 15409538
Soyoung A. Oh; Kate Senger; Shravan Madireddi; Ilseyar Akhmetzyanova; Isabel E. Ishizuka; Somayeh S. Tarighat; Jerry H. Lo; David Shaw; Benjamin Haley; Sascha Rutz
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Generation of a Porcine Antibody Fab Fragment Using Protein Engineering to Facilitate the Evaluation of Ocular Sustained Delivery Technology
Molecular Pharmaceutics, ISSN: 15438392 15438384
Robert F. Kelley; Devin B. Tesar; Yue Wang; Nick Agard; Patrick Holder; Joyce Chan; Laetitia Comps-Agrar; Judit Horvath; Joshua Horvath; Susan R. Crowell
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High-efficiency nonviral CRISPR/Cas9-mediated gene editing of human T cells using plasmid donor DNA
Journal of Experimental Medicine, ISSN: 15409538 00221007
Soyoung A. Oh; Kate Senger; Shravan Madireddi; Ilseyar Akhmetzyanova; Isabel E. Ishizuka; Somayeh S. Tarighat; Jerry H. Lo; David Shaw; Benjamin Haley; Sascha Rutz
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Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation
Nature Genetics, ISSN: 15461718 10614036
Anubha Mahajan; Cassandra N Spracklen; Weihua Zhang; Maggie C. Y. Ng; Lauren E. Petty; Hidetoshi Kitajima; Grace Zhuo Yu; Sina Rüeger; Leo Speidel; Young Jin Kim; Momoko Horikoshi; Josep M. Mercader; Daniel Taliun; Sanghoon Moon; Soo-Heon Kwak; Neil R. Robertson; N. William Rayner; Marie Loh; Bong-Jo Kim; Joshua Chiou; Irene Miguel-Escalada; Kuang Lin; Fiona Bragg; Michael Preuss; Fumihiko Takeuchi; Jana Nano; Xiuqing Guo; Amel Lamri; Masahiro Nakatochi; Robert A Scott; Jung-Jin Lee; Alicia Huerta-Chagoya; Mariaelisa Graff; Jin-Fang Chai; Esteban J. Parra; Jie Yao; Lawrence F Bielak; Yasuharu Tabara; Yang Hai; Valgerdur Steinthorsdottir; James Cook; Mart Kals; Niels Grarup; Ellen Schmidt; Ian Pan; Tamar Sofer; Matthias Wuttke; Chloe Sarnowski; Christian Gieger; Darryl Nousome; Stella Trompet; Jirong Long; Meng Sun; Lin Tong; Wei-Min Chen; Meraj Ahmad; Raymond Noordam; Victor J. Y. Lim; Claudia H. T. Tam; Yoonjung Yoonie Joo; Chien-Hsiun Chen; Laura Raffield; Cecile Lecoeur; Bram P. Prins; Aude Nicolas; Lisa R. Yanek; Guanjie Chen; Richard A. Jensen; Salman M Tajuddin; Edmond Kato Kabagambe; Ping An; Anny H. Xiang; Hyeok Sun Choi; Brian E. Cade; Jingyi Tan; Jack Flanagan; Fernando Abaitua; Linda S. Adair; Adebowale A Adeyemo; Carlos A. Aguilar-Salinas; Masato Akiyama; Sonia S. Anand; Alain Bertoni; Zheng Bian; Jette Bork-Jensen; Ivan Brandslund; Jennifer A Brody; Chad M. Brummett; Thomas A. Buchanan; Mickaël Canouil; Juliana C. N. Chan; Li-Ching Chang; Miao-Li Chee; Ji Chen; Shyh-Huei Chen; Yuan-Tsong Chen; Zhengming Chen; Lee-Ming Chuang; Mary Cushman; Swapan K. Das; H Janaka de Silva; George Dedoussis; Latchezar M. Dimitrov; Ayo P Doumatey; Shufa Du; Qing Duan; Kai-Uwe Eckardt; Leslie S. Emery; Daniel S. Evans; Michele K Evans; Krista Fischer; James S. Floyd; Ian Ford; Myriam Fornage; Oscar H. Franco; Timothy M. Frayling; Barry I. Freedman; Christian Fuchsberger; Pauline Genter; Hertzel C. Gerstein; Vilmantas Giedraitis; Clicerio Gonzalez-Villalpando; Maria Elena González-Villalpando; Mark O Goodarzi; Penny Gordon-Larsen; David Gorkin; Myron Gross; Yu Guo; Sophie Hackinger; Sohee Han; Andrew T. Hattersley; Christian Herder; Annie-Green Howard; Willa A. Hsueh; Mengna Huang; Wei Huang; Yi-Jen Hung; Mi Yeong Hwang; Chii-Min Hwu; Sahoko Ichihara; M Arfan Ikram; Martin Ingelsson; Md Tariqul Islam; Masato Isono; Hye-Mi Jang; Farzana Jasmine; Guozhi Jiang; Jost B Jonas; Marit E. Jørgensen; Torben Jørgensen; Yoichiro Kamatani; Fouad R. Kandeel; Anuradhani Kasturiratne; Tomohiro Katsuya; Varinderpal Kaur; Takahisa Kawaguchi; Jacob M. Keaton; Abel N. Kho; Chiea Chuen Khor; Muhammad G. Kibriya; Duk-Hwan Kim; Katsuhiko Kohara; Jennifer Kriebel; Florian Kronenberg; Johanna Kuusisto; Kristi Läll; Leslie A. Lange; Myung-Shik Lee; Nanette R. Lee; Aaron Leong; Liming Li; Yun Li; Ruifang Li-Gao; Symen Ligthart; Cecilia M. Lindgren; Allan Linneberg; Ching-Ti Liu; Jianjun Liu; Adam E. Locke; Tin Louie; Jian’an Luan; Andrea O. Luk; Xi Luo; Jun Lv; Valeriya Lyssenko; Vasiliki Mamakou; K. Radha Mani; Thomas Meitinger; Andres Metspalu; Andrew Morris; Girish Nadkarni; Jerry L. Nadler; Michael A. Nalls; Uma Nayak; Suraj S. Nongmaithem; Ioanna Ntalla; Yukinori Okada; Lorena Orozco; Sanjey R. Patel; Mark A. Pereira; Annette Peters; Fraser J. Pirie; Bianca Porneala; Gauri Prasad; Sebastian Preissl; Laura J. Rasmussen-Torvik; Alex Reiner; Michael Roden; Rebecca Rohde; Kathryn Roll; Charumathi Sabanayagam; Maike Sander; Kevin Sandow; Naveed Sattar; Sebastian Schönherr; Claudia Schurmann; Mohammad Shahriar; Jinxiu Shi; Dong Mun Shin; Daniel Shriner; Jennifer A. Smith; Wing Yee So; Alena Stančáková; Adrienne Stilp; Konstantin Strauch; Ken Suzuki; Atsushi Takahashi; Kent D. Taylor; Barbara Thorand; Gudmar Thorleifsson; Unnur Thorsteinsdottir; Brian Tomlinson; Jason M. Torres; Fuu-Jen Tsai; Jaakko Tuomilehto; Teresa Tusié-Luna; Miriam S. Udler; Adan Valladares-Salgado; Rob M van Dam; Jan B. van Klinken; Rohit Varma; Marijana Vujkovic; Niels Wacher-Rodarte; Eleanor Wheeler; Eric A. Whitsel; Ananda R. Wickremasinghe; Ko Willems van Dijk; Daniel R. Witte; Chittaranjan S Yajnik; Ken Yamamoto; Toshimasa Yamauchi; Loic Yengo; Kyungheon Yoon; Canqing Yu; Jian-Min Yuan; Salim Yusuf; Liang Zhang; Wei Zheng; Sina Rüeger; Pietro della Briotta Parolo; Yoonjung Yoonie Joo; M. Geoffrey Hayes; Leslie J. Raffel; Michiya Igase; Eli Ipp; Susan Redline; Yoon Shin Cho; Lars Lind; Michael A. Province; Craig L. Hanis; Patricia A Peyser; Erik Ingelsson; Alan B. Zonderman; Bruce M. Psaty; Ya Xing Wang; Charles Rotimi; Diane M Becker; Fumihiko Matsuda; Yongmei Liu; Eleftheria Zeggini; Mitsuhiro Yokota; Stephen S. Rich; Charles Kooperberg; James S. Pankow; James C. Engert; Yii-Der Ida Chen; Philippe Froguel; James G. Wilson; Wayne H. H. Sheu; Sharon L.R. Kardia; Jer-Yuarn Wu; M. Geoffrey Hayes; Ronald C. W. Ma; Tien-Yin Wong; Leif Groop; Dennis Mook-Kanamori; Giriraj Ratan Chandak; Francis S Collins; Dwaipayan Bharadwaj; Guillaume Pare; Michèle M. Sale; Habibul Ahsan; Ayesha A. Motala; Xiao-Ou Shu; Kyong-Soo Park; J Wouter Jukema; Miguel Cruz; Roberta Mckean-Cowdin; Harald Grallert; Ching-Yu Cheng; Erwin P Bottinger; Abbas Dehghan; E-Shyong Tai; Josée Dupuis; Norihiro Kato; Markku Laakso; Anna Köttgen; Woon-Puay Koh; Colin Palmer; Simin Liu; Goncalo R. Abecasis; Jaspal S Kooner; Ruth J. F. Loos; Kari E. North; Christopher A. Haiman; Jose C. Florez; Danish Saleheen; Torben Hansen; Oluf Pedersen; Reedik Mägi; Claudia Langenberg; Nicholas J Wareham; Shiro Maeda; Takashi Kadowaki; Juyoung Lee; Iona Y Millwood; Robin G. Walters; Kari Stefansson; Simon R. Myers; Jorge Ferrer; Kyle J. Gaulton; James B. Meigs; Karen L. Mohlke; Anna L. Gloyn; Donald W. Bowden; Jennifer E. Below; John C Chambers; Xueling Sim; Michael Boehnke; Jerome I. Rotter; Mark I. McCarthy; Andrew P. Morris
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RIP1 post-translational modifications
Biochemical Journal, ISSN: 02646021
Eugene Varfolomeev; Domagoj Vucic
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2021 White Paper on Recent Issues in Bioanalysis: Mass Spec of Proteins, Extracellular Vesicles, CRISPR, Chiral Assays, Oligos;
Bioanalysis, ISSN: 17576199 17576180
Surinder Kaur; Stephen C. Alley; Matthew Szapacs; Amanda Wilson; Eugene Ciccimaro; Dian Su; Neil Henderson; Lin-Zhi Chen; Fabio Garofolo; Shawna Hengel; Wenying Jian; John Kellie; Anita Lee; John T. Mehl; Joe Palandra; Haibo Qiu; Natasha Savoie; Diaa Shakleya; Ludovicus Staelens; Hiroshi Sugimoto; Giane Sumner; Jan Welink; Robert Wheller; Xue; Jianing Zeng; Jinhui Zhang; Huiyu Zhou; Jian Wang; Scott Summerfield; Lieve Dillen; Ragu Ramanathan; Mike Baratta; Arindam Dasgupta; Anna Edmison; Luca Ferrari; Sally Fischer; Daniela Fraier; Sam Haidar; Kathrin Heermeier; Christopher James; Allena Ji; Lina Luo; Gustavo Mendes Lima Santos; Noah Post; Anton I Rosenbaum; Sune Sporring; Sekhar Surapaneni; Stephen Vinter; Katty Wan; Eric Woolf; Olga Kavetska; Seongeun Cho; Elham Kossary; Sandra Prior; Mohsen Rajabi Abhari; Catherine Soo; Yow-Ming C. Wang; Abbas Bandukwala; Elana Cherry; Isabelle Cludts; Soma Ghosh; Shirley Hopper; Akiko Ishii-Watabe; Susan Kirshner; Kevin Maher; Kimberly Maxfield; Joao Pedras-Vasconcelos; Yoshiro Saito; Dean Smith; Therese Solstad; Verthelyi; Meenu Wadhwa; Leslie Wagner; Günter Waxenecker; Haoheng Yan; Lucia Zhang
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RIP1 post-translational modifications
Biochemical Journal, ISSN: 14708728 02646021
Eugene Varfolomeev; Domagoj Vucic
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Nonclinical Pharmacokinetics and Pharmacodynamics Characterization of Anti-CD79b/CD3 T Cell-Dependent Bispecific Antibody Using a Surrogate Molecule: A Potential Therapeutic Agent for B Cell Malignancies
Pharmaceutics, ISSN: 19994923
Rajbharan Yadav; Siddharth Sukumaran; Tanja S. Zabka; Jinze Li; Amy Oldendorp; Gary Morrow; Arthur Reyes; Melissa Cheu; Jessica Li; Jeffrey J. Wallin; Siao Tsai; Laura Sun; Peiyin Wang; Diego Ellerman; Christoph Spiess; Andrew G. Polson; Stefanich; Amrita Kamath; Meric A. Ovacik
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A Fit-for-Purpose Method to Measure Circulating Levels of the mRNA Component of a Liposomal-Formulated Individualized Neoantigen-Specific Therapy for Cancer
AAPS Journal, ISSN: 15507416
Sebastián Guelman; Ying Zhou; Ann Brady; Kun Peng
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Plasma-Based Measurements of Tumor Heterogeneity Correlate with Clinical Outcomes in Metastatic Colorectal Cancer
Cancers, ISSN: 20726694
Stephanie J. Yaung; Christine Ju; Sandeep Gattam; Alan Nicholas; Nicolas Sommer; Bendell; Herbert Hurwitz; John J. Lee; Fergal Casey; Richard Price; John F. Palma
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Astegolimab, an anti-ST2, in chronic obstructive pulmonary disease (COPD-ST2OP): a phase 2a, placebo-controlled trial
The Lancet Respiratory Medicine, ISSN: 22132619 22132600
Ahmed J Yousuf; Seid Mohammed; Liesl Carr; Mohammadali Yavari Ramsheh; Claudia Micieli; Vijay Mistry; Kairobi Haldar; Adam K. A. Wright; Petr Novotny; Sarah Parker; Sarah Glover; Joanne Finch; Niamh Quann; Cassandra L Brookes; Rachel Hobson; Wadah Ibrahim; Richard J Russell; Catherine John; Michele A. Grimbaldeston; David F. Choy; Dorothy Cheung; Michael Steiner; Neil J Greening; Chris E. Brightling
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Tumor Growth Inhibition-Overall Survival (TGI-OS) Model for Subgroup Analysis Based on Post-Randomization Factors: Application for Anti-drug Antibody (ADA) Subgroup Analysis of Atezolizumab in the IMpower150 Study
AAPS Journal, ISSN: 15507416
Yoshida; Phyllis Chan; Mathilde Marchand; Rong Zhang; Benjamin Wu; Ballinger; Nitzan Sternheim; Jin; Rene Bruno
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Pre- and post-treatment blood-based genomic landscape of patients with ROS1 or NTRK fusion-positive solid tumours treated with entrectinib
Molecular Oncology, ISSN: 18780261 15747891
Rafal Dziadziuszko; Tiffany Hung; Kun Wang; Voleak Choeurng; Alexander Drilon; Robert C Doebele; Fabrice Barlesi; Charlie Wu; Lucas Dennis; Skoletsky; Ryan Woodhouse; Meijuan Li; Ching-Wei Chang; Brian Simmons; Todd Riehl; Wilson
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Global intercompany assessment of ICIEF platform comparability for the characterization of therapeutic proteins
Electrophoresis, ISSN: 15222683 01730835
Seth Madren; Will McElroy; Kristin Schultz-Kuszak; Boris Boumajny; Yao Shu; Sabine Sautter; Helen C. Zhao; Abby Schadock-Hewitt; Chris M. Chumsae; Nancy Ball; Xiaoying Zhang; Kimberly Rish; Shukui Zhang; Christine Wurm; Sumin Cai; Scott P. Bauer; Cinzia Stella; Laura Zheng; Brian Roper; David A. Michels; Gang Wu; Bostjan Kocjan; Matej Birk; Simon Erik Erdmann; Xiaoping He; Brad Whittaker; Yvonne Song; Hannah Barrett; Kevin Strozyk; Ye Jing; Long Huang; Vishal Mhatre; Paul McLean; Tiantian Yu; Huijuan Yang; Minna Mattila
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Phase I and scintigraphy studies to evaluate safety, tolerability, pharmacokinetics, and lung deposition of inhaled GDC-0214 in healthy volunteers
Clinical and Translational Science, ISSN: 17528062 17528054
Rui Zhu; Hubert Chen; Joshua Galanter; Gaohong She; Fang Cai; Matthew Durk; Yixuan Zou; Liuxi Chen; Jane R. Kenny; Shweta Vadhavkar; Simon Warren; Glyn Taylor; Olivia Hwang; Avi Eliahu; Chris Wynne; Ryan Owen
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Quantitative systems pharmacology model-based investigation of adverse gastrointestinal events associated with prolonged treatment with PI3-kinase inhibitors
CPT: Pharmacometrics and Systems Pharmacology, ISSN: 21638306
Kapil Gadkar; Christina M. Friedrich; Vincent Hurez; Maria-Luisa Ruiz; Leslie Dickmann; Mohit Kumar Jolly; Leah Schutt; Jin Jin; Joseph A. Ware; Ramanujan
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Safety and Clinical Activity of Atezolizumab Plus Ipilimumab in Locally Advanced or Metastatic Non–Small Cell Lung Cancer: Results From a Phase 1b Trial
Clinical Lung Cancer, ISSN: 19380690 15257304
Wong; Todd M. Bauer; Michael S. Gordon; Fabiola Bene-Tchaleu; Jing Zhu; Xiaosong Zhang; Edward Cha
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Double-layer sign in neovascular age-related macular degeneration – do we treat?
Acta Ophthalmologica, ISSN: 17553768 1755375X
Andreas Berlin; Ling Chen; Jeffrey D. Messinger; Daniela Ferrara; K. Bailey Freund; Christine A. Curcio
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In-vitro characterization of ranibizumab release from the Port Delivery System
Journal of Controlled Release, ISSN: 18734995 01683659
Stefan T. Yohe; Katie F. Maass; Judit Horvath; Jennifer Rea; Giulio Barteselli; Shrirang Ranade
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Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation
Nature Genetics, ISSN: 15461718 10614036
Anubha Mahajan; Cassandra N Spracklen; Weihua Zhang; Maggie C. Y. Ng; Lauren E. Petty; Hidetoshi Kitajima; Grace Zhuo Yu; Sina Rüeger; Leo Speidel; Young Jin Kim; Momoko Horikoshi; Josep M. Mercader; Daniel Taliun; Sanghoon Moon; Soo-Heon Kwak; Neil R. Robertson; N. William Rayner; Marie Loh; Bong-Jo Kim; Joshua Chiou; Irene Miguel-Escalada; Kuang Lin; Fiona Bragg; Michael Preuss; Fumihiko Takeuchi; Jana Nano; Xiuqing Guo; Amel Lamri; Masahiro Nakatochi; Robert A Scott; Jung-Jin Lee; Alicia Huerta-Chagoya; Mariaelisa Graff; Jin-Fang Chai; Esteban J. Parra; Jie Yao; Lawrence F Bielak; Yasuharu Tabara; Yang Hai; Valgerdur Steinthorsdottir; James Cook; Mart Kals; Niels Grarup; Ellen Schmidt; Ian Pan; Tamar Sofer; Matthias Wuttke; Chloe Sarnowski; Christian Gieger; Darryl Nousome; Stella Trompet; Jirong Long; Meng Sun; Lin Tong; Wei-Min Chen; Meraj Ahmad; Raymond Noordam; Victor J. Y. Lim; Claudia H. T. Tam; Yoonjung Yoonie Joo; Chien-Hsiun Chen; Laura Raffield; Cecile Lecoeur; Bram P. Prins; Aude Nicolas; Lisa Yanek; Guanjie Chen; Richard A. Jensen; Salman M Tajuddin; Edmond Kato Kabagambe; Ping An; Anny H. Xiang; Hyeok Sun Choi; Brian E. Cade; Jingyi Tan; Jack Flanagan; Fernando Abaitua; Linda S. Adair; Adebowale A Adeyemo; Carlos A. Aguilar-Salinas; Masato Akiyama; Sonia S. Anand; Alain Bertoni; Zheng Bian; Jette Bork-Jensen; Ivan Brandslund; Jennifer A Brody; Chad M. Brummett; Thomas A. Buchanan; Mickaël Canouil; Juliana C. N. Chan; Li-Ching Chang; Miao-Li Chee; Ji Chen; Shyh-Huei Chen; Yuan-Tsong Chen; Zhengming Chen; Lee-Ming Chuang; Mary Cushman; Swapan K. Das; H Janaka de Silva; George Dedoussis; Latchezar M. Dimitrov; Ayo P Doumatey; Shufa Du; Qing Duan; Kai-Uwe Eckardt; Leslie S. Emery; Daniel S. Evans; Michele K Evans; Krista Fischer; James S. Floyd; Ian Ford; Myriam Fornage; Oscar H. Franco; Timothy M. Frayling; Barry I. Freedman; Christian Fuchsberger; Pauline Genter; Hertzel C. Gerstein; Vilmantas Giedraitis; Clicerio Gonzalez-Villalpando; Maria Elena González-Villalpando; Mark O Goodarzi; Penny Gordon-Larsen; David Gorkin; Myron Gross; Yu Guo; Sophie Hackinger; Sohee Han; Andrew T. Hattersley; Christian Herder; Annie-Green Howard; Willa A. Hsueh; Mengna Huang; Wei Huang; Yi-Jen Hung; Mi Yeong Hwang; Chii-Min Hwu; Sahoko Ichihara; M Arfan Ikram; Martin Ingelsson; Md Tariqul Islam; Masato Isono; Hye-Mi Jang; Farzana Jasmine; Guozhi Jiang; Jost B Jonas; Marit E. Jørgensen; Torben Jørgensen; Yoichiro Kamatani; Fouad R. Kandeel; Anuradhani Kasturiratne; Tomohiro Katsuya; Varinderpal Kaur; Takahisa Kawaguchi; Jacob M. Keaton; Abel N. Kho; Chiea Chuen Khor; Muhammad G. Kibriya; Duk-Hwan Kim; Katsuhiko Kohara; Jennifer Kriebel; Florian Kronenberg; Johanna Kuusisto; Kristi Läll; Leslie A. Lange; Myung-Shik Lee; Nanette R. Lee; Aaron Leong; Liming Li; Yun Li; Ruifang Li-Gao; Symen Ligthart; Cecilia M. Lindgren; Allan Linneberg; Ching-Ti Liu; Jianjun Liu; Adam E. Locke; Tin Louie; Jian’an Luan; Andrea O. Luk; Xi Luo; Jun Lv; Valeriya Lyssenko; Vasiliki Mamakou; K. Radha Mani; Thomas Meitinger; Andres Metspalu; Andrew Morris; Girish Nadkarni; Jerry L. Nadler; Michael A. Nalls; Uma Nayak; Suraj S. Nongmaithem; Ioanna Ntalla; Cecilia M. Lindgren; Lorena Orozco; Sanjey R. Patel; Mark A. Pereira; Annette Peters; Fraser J. Pirie; Bianca Porneala; Gauri Prasad; Sebastian Preissl; Laura J. Rasmussen-Torvik; Alex Reiner; Michael Roden; Rebecca Rohde; Kathryn Roll; Charumathi Sabanayagam; Maike Sander; Kevin Sandow; Naveed Sattar; Sebastian Schönherr; Claudia Schurmann; Mohammad Shahriar; Jinxiu Shi; Dong Mun Shin; Daniel Shriner; Jennifer A. Smith; Wing Yee So; Alena Stančáková; Adrienne Stilp; Konstantin Strauch; Ken Suzuki; Atsushi Takahashi; Kent D. Taylor; Barbara Thorand; Gudmar Thorleifsson; Unnur Thorsteinsdottir; Brian Tomlinson; Jason M. Torres; Fuu-Jen Tsai; Jaakko Tuomilehto; Teresa Tusié-Luna; Miriam S. Udler; Adan Valladares-Salgado; Rob M van Dam; Jan B. van Klinken; Rohit Varma; Marijana Vujkovic; Niels Wacher-Rodarte; Eleanor Wheeler; Eric A. Whitsel; Ananda R. Wickremasinghe; Ko Willems van Dijk; Daniel R. Witte; Chittaranjan S Yajnik; Ken Yamamoto; Toshimasa Yamauchi; Loic Yengo; Kyungheon Yoon; Canqing Yu; Jian-Min Yuan; Salim Yusuf; Liang Zhang; Wei Zheng; Sina Rüeger; Pietro della Briotta Parolo; M. Geoffrey Hayes; Leslie J. Raffel; Michiya Igase; Eli Ipp; Susan Redline; Yoon Shin Cho; Lars Lind; Michael A. Province; Craig L. Hanis; Patricia A Peyser; Erik Ingelsson; Alan B. Zonderman; Bruce M. Psaty; Ya Xing Wang; Charles Rotimi; Diane M Becker; Fumihiko Matsuda; Yongmei Liu; Eleftheria Zeggini; Mitsuhiro Yokota; Stephen S. Rich; Charles Kooperberg; James S. Pankow; James C. Engert; Yii-Der Ida Chen; Philippe Froguel; James G. Wilson; Wayne H. H. Sheu; Sharon L.R. Kardia; Jer-Yuarn Wu; M. Geoffrey Hayes; Ronald C. W. Ma; Tien-Yin Wong; Leif Groop; Dennis Mook-Kanamori; Giriraj Ratan Chandak; Francis S Collins; Dwaipayan Bharadwaj; Guillaume Pare; Michèle M. Sale; Habibul Ahsan; Ayesha A. Motala; Xiao-Ou Shu; Kyong-Soo Park; J Wouter Jukema; Miguel Cruz; Roberta Mckean-Cowdin; Harald Grallert; Ching-Yu Cheng; Erwin P Bottinger; Abbas Dehghan; E-Shyong Tai; Josée Dupuis; Norihiro Kato; Markku Laakso; Anna Köttgen; Woon-Puay Koh; Colin Palmer; Simin Liu; Goncalo R. Abecasis; Jaspal S Kooner; Ruth J. F. Loos; Kari E. North; Christopher A. Haiman; Jose C. Florez; Danish Saleheen; Torben Hansen; Oluf Pedersen; Reedik Mägi; Claudia Langenberg; Nicholas J Wareham; Shiro Maeda; Takashi Kadowaki; Juyoung Lee; Iona Y Millwood; Robin G. Walters; Kari Stefansson; Simon R. Myers; Jorge Ferrer; Kyle J. Gaulton; James B. Meigs; Karen L. Mohlke; Anna L. Gloyn; Donald W. Bowden; Jennifer E. Below; John C Chambers; Xueling Sim; Michael Boehnke; Jerome I. Rotter; Mark I. McCarthy; Andrew P. Morris
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Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation
Nature Genetics, ISSN: 10614036
Anubha Mahajan; Cassandra N Spracklen; Weihua Zhang; Maggie C. Y. Ng; Lauren E. Petty; Hidetoshi Kitajima; Grace Zhuo Yu; Sina Rüeger; Leo Speidel; Young Jin Kim; Momoko Horikoshi; Josep M. Mercader; Daniel Taliun; Sanghoon Moon; Soo-Heon Kwak; Neil R. Robertson; N. William Rayner; Marie Loh; Bong-Jo Kim; Joshua Chiou; Irene Miguel-Escalada; Kuang Lin; Fiona Bragg; Michael Preuss; Fumihiko Takeuchi; Jana Nano; Xiuqing Guo; Amel Lamri; Masahiro Nakatochi; Robert A Scott; Jung-Jin Lee; Alicia Huerta-Chagoya; Mariaelisa Graff; Jin-Fang Chai; Esteban J. Parra; Jie Yao; Lawrence F Bielak; Yasuharu Tabara; Yang Hai; Valgerdur Steinthorsdottir; James Cook; Mart Kals; Niels Grarup; Ellen Schmidt; Ian Pan; Tamar Sofer; Matthias Wuttke; Chloe Sarnowski; Christian Gieger; Darryl Nousome; Stella Trompet; Jirong Long; Meng Sun; Lin Tong; Wei-Min Chen; Meraj Ahmad; Raymond Noordam; Victor J. Y. Lim; Claudia H. T. Tam; Yoonjung Yoonie Joo; Chien-Hsiun Chen; Laura Raffield; Cecile Lecoeur; Bram P. Prins; Aude Nicolas; Lisa R. Yanek; Guanjie Chen; Richard A. Jensen; Salman M Tajuddin; Edmond Kato Kabagambe; Ping An; Anny H. Xiang; Hyeok Sun Choi; Brian E. Cade; Jingyi Tan; Jack Flanagan; Fernando Abaitua; Linda S. Adair; Adebowale A Adeyemo; Carlos A. Aguilar-Salinas; Masato Akiyama; Sonia S. Anand; Alain Bertoni; Zheng Bian; Jette Bork-Jensen; Ivan Brandslund; Jennifer A Brody; Chad M. Brummett; Thomas A. Buchanan; Mickaël Canouil; Juliana C. N. Chan; Li-Ching Chang; Miao-Li Chee; Ji Chen; Shyh-Huei Chen; Yuan-Tsong Chen; Zhengming Chen; Lee-Ming Chuang; Mary Cushman; Swapan K. Das; H Janaka de Silva; George Dedoussis; Latchezar M. Dimitrov; Ayo P Doumatey; Shufa Du; Qing Duan; Kai-Uwe Eckardt; Leslie S. Emery; Daniel S. Evans; Michele K Evans; Krista Fischer; James S. Floyd; Ian Ford; Myriam Fornage; Oscar H. Franco; Timothy M. Frayling; Barry I. Freedman; Christian Fuchsberger; Pauline Genter; Hertzel C. Gerstein; Vilmantas Giedraitis; Clicerio Gonzalez-Villalpando; Maria Elena González-Villalpando; Mark O Goodarzi; Penny Gordon-Larsen; David Gorkin; Myron Gross; Yu Guo; Sophie Hackinger; Sohee Han; Andrew T. Hattersley; Christian Herder; Annie-Green Howard; Willa Hsueh; Mengna Huang; Wei Huang; Yi-Jen Hung; Mi Yeong Hwang; Chii-Min Hwu; Sahoko Ichihara; M Arfan Ikram; Martin Ingelsson; Md Tariqul Islam; Masato Isono; Hye-Mi Jang; Farzana Jasmine; Guozhi Jiang; Jost B Jonas; Marit E. Jørgensen; Torben Jørgensen; Yoichiro Kamatani; Fouad R. Kandeel; Anuradhani Kasturiratne; Tomohiro Katsuya; Varinderpal Kaur; Takahisa Kawaguchi; Jacob M. Keaton; Abel N. Kho; Chiea Chuen Khor; Muhammad G. Kibriya; Duk-Hwan Kim; Katsuhiko Kohara; Jennifer Kriebel; Florian Kronenberg; Johanna Kuusisto; Kristi Läll; Leslie A. Lange; Myung-Shik Lee; Nanette R. Lee; Aaron Leong; Liming Li; Yun Li; Ruifang Li-Gao; Symen Ligthart; Cecilia M. Lindgren; Allan Linneberg; Ching-Ti Liu; Jianjun Liu; Adam E. Locke; Tin Louie; Jian’an Luan; Andrea O. Luk; Xi Luo; Jun Lv; Valeriya Lyssenko; Vasiliki Mamakou; K. Radha Mani; Thomas Meitinger; Andres Metspalu; Andrew Morris; Girish Nadkarni; Jerry L. Nadler; Michael A. Nalls; Uma Nayak; Suraj S. Nongmaithem; Ioanna Ntalla; Yukinori Okada; Lorena Orozco; Sanjey R. Patel; Mark A. Pereira; Annette Peters; Fraser J. Pirie; Bianca Porneala; Gauri Prasad; Sebastian Preissl; Laura J. Rasmussen-Torvik; Alex Reiner; Michael Roden; Rebecca Rohde; Kathryn Roll; Charumathi Sabanayagam; Maike Sander; Kevin Sandow; Naveed Sattar; Sebastian Schönherr; Claudia Schurmann; Mohammad Shahriar; Jinxiu Shi; Dong Mun Shin; Daniel Shriner; Jennifer A. Smith; Wing Yee So; Alena Stančáková; Adrienne Stilp; Konstantin Strauch; Ken Suzuki; Atsushi Takahashi; Kent D. Taylor; Barbara Thorand; Gudmar Thorleifsson; Unnur Thorsteinsdottir; Brian Tomlinson; Jason M. Torres; Fuu-Jen Tsai; Jaakko Tuomilehto; Teresa Tusié-Luna; Miriam S. Udler; Adan Valladares-Salgado; Rob M van Dam; Jan B. van Klinken; Rohit Varma; Marijana Vujkovic; Niels Wacher-Rodarte; Eleanor Wheeler; Eric A. Whitsel; Ananda R. Wickremasinghe; Ko Willems van Dijk; Daniel R. Witte; Chittaranjan S Yajnik; Ken Yamamoto; Toshimasa Yamauchi; Loic Yengo; Kyungheon Yoon; Canqing Yu; Jian-Min Yuan; Salim Yusuf; Liang Zhang; Wei Zheng; Sina Rüeger; Pietro della Briotta Parolo; Yoonjung Yoonie Joo; M. Geoffrey Hayes; Leslie J. Raffel; Michiya Igase; Eli Ipp; Susan Redline; Yoon Shin Cho; Lars Lind; Michael A. Province; Craig L. Hanis; Patricia A Peyser; Erik Ingelsson; Alan B. Zonderman; Bruce M. Psaty; Ya Xing Wang; Charles Rotimi; Diane M. Becker; Fumihiko Matsuda; Yongmei Liu; Eleftheria Zeggini; Mitsuhiro Yokota; Stephen S. Rich; Charles Kooperberg; James S. Pankow; James C. Engert; Yii-Der Ida Chen; Philippe Froguel; James G. Wilson; Wayne H. H. Sheu; Sharon L.R. Kardia; Jer-Yuarn Wu; M. Geoffrey Hayes; Ronald C. W. Ma; Tien-Yin Wong; Leif Groop; Dennis Mook-Kanamori; Giriraj Ratan Chandak; Francis S Collins; Dwaipayan Bharadwaj; Guillaume Pare; Michèle M. Sale; Habibul Ahsan; Ayesha A. Motala; Xiao-Ou Shu; Kyong-Soo Park; J Wouter Jukema; Miguel Cruz; Roberta Mckean-Cowdin; Harald Grallert; Ching-Yu Cheng; Erwin P Bottinger; Abbas Dehghan; E-Shyong Tai; Josée Dupuis; Norihiro Kato; Markku Laakso; Anna Köttgen; Woon-Puay Koh; Colin Palmer; Simin Liu; Goncalo R. Abecasis; Jaspal S Kooner; Ruth J. F. Loos; Kari E. North; Christopher A. Haiman; Jose C. Florez; Danish Saleheen; Torben Hansen; Oluf Pedersen; Reedik Mägi; Claudia Langenberg; Nicholas J Wareham; Shiro Maeda; Takashi Kadowaki; Juyoung Lee; Iona Y Millwood; Robin G. Walters; Kari Stefansson; Simon R. Myers; Jorge Ferrer; Kyle J. Gaulton; James B. Meigs; Karen L. Mohlke; Anna L. Gloyn; Donald W. Bowden; Jennifer E. Below; John C Chambers; Xueling Sim; Michael Boehnke; Jerome I. Rotter; Mark I. McCarthy; Andrew P. Morris
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Pertuzumab Plus Trastuzumab for Treatment-Refractory HER2-Amplified Metastatic Colorectal Cancer: Comparison of the MyPathway Trial With a Real-World External Control Arm
JCO Clinical Cancer Informatics,
Yusuke Narita; Takuya Yoshimoto; Tomoyuki Namai; Takashi Asakawa; Satoe Kawakami; Craig Gower-Page; Reyes-Rivera; Arisha Patel; Yoshiaki Nakamura
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Cobimetinib in Pediatric and Young Adult Patients with Relapsed or Refractory Solid Tumors (iMATRIX-cobi): A Multicenter, Phase I/II Study
Targeted Oncology, ISSN: 17762596
Tanya Trippett; Helen Toledano; Quentin Campbell Hewson; Arnauld Verschuur; Anne-Marie Langevin; Isabelle Aerts; Lisa Howell; Soledad Gallego; Claudia Rossig; Amy Smith; Darshak Patel; Leonardo R. Pereira; Sravanthi Cheeti; Luna Musib; Katherine E. Hutchinson; Clare Devlin; Ronald Bernardi; Birgit Geoerger
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Implant Insertion Procedure of the Port Delivery System With Ranibizumab: Overview and Clinical Pearls
Ophthalmic Surgery Lasers and Imaging Retina, ISSN: 23258179 23258160
Dante Joseph Pieramici; Mark R. Wieland; Jay M. Stewart; Robert T. Chang; Shamika Gune; Varun Malhotra; Giulio Barteselli; Carl C. Awh
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Conjunctiva and Tenon’s Capsule Handling in the Port Delivery System with Ranibizumab Implant Insertion Procedure: Surgical Pearls
Ophthalmic Surgery Lasers and Imaging Retina, ISSN: 23258179 23258160
Jordan M. Graff; Veeral S. Sheth; Robert T. Chang; Alicia R. Menezes; Giulio Barteselli; Varun Malhotra
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Refill-Exchange Procedure of the Port Delivery System With Ranibizumab: Overview and Clinical Trial Experience
Ophthalmic Surgery Lasers and Imaging Retina, ISSN: 23258179 23258160
Arshad M. Khanani; Jordan M. Graff; Dennis Marcus; Charles C. Wykoff; Chirag D. Jhaveri; Giulio Barteselli; Varun Malhotra; Alicia R. Menezes; Natalia F. Callaway
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Tocilizumab in patients hospitalised with COVID-19 pneumonia: Efficacy, safety, viral clearance, and antibody response from a randomised controlled trial (COVACTA)
EClinicalMedicine, ISSN: 25895370
Ivan O. Rosas; Norbert Bräu; Michael Waters; Ronaldo C. Go; Atul Malhotra; Bradley D. Hunter; Sanjay Bhagani; Daniel Skiest; Sinisa Savic; Ivor S. Douglas; Julia Garcia-Diaz; Mariam S. Aziz; Nichola Cooper; Taryn Youngstein; Lorenzo Del Sorbo; David J. De La Zerda; Andrew Ustianowski; Antonio Cubillo Gracian; Kevin G. Blyth; Jordi Carratalà; Bruno François; Thomas Benfield; Derrick Haslem; Paolo Bonfanti; Cor H. van der Leest; Nidhi Rohatgi; Lothar Wiese; Charles Edouard Luyt; Rebecca N. Bauer; Fang Cai; Ivan T. Lee; Balpreet Matharu; Louis Metcalf; Steffen Wildum; Emily Graham; Larry Tsai; Bao
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