Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 12001 - 12050 OF 15570 RESULTS

Biologic effects of heregulin/neu differentiation factor on normal and malignant human breast and ovarian epithelial cells
Oncogene, ISSN: 09509232
Zuleima Aguilar; Robert W. Akita; Richard S. Finn; B. Lillian Ramos; Pegram; Fairooz F. Kabbinavar; Pietras; Paul Pisacane; Mark X. Sliwkowski; Dennis J. Slamon
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Evidence for a protective role of metallothionein-1 in focal cerebral ischemia
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Menno Van Lookeren Campagne; Harold Thibodeaux; Nicholas Van Bruggen; Cairns; Gerlai; James T. Palmer; Simon P. Williams; David G Lowe
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Progressive cardiac dysfunction and fibrosis in the cardiomyopathic hamster and effects of growth hormone and angiotensin-converting enzyme inhibition
Circulation, ISSN: 00097322
Tsutomu Ryoke; Yusu Gu; Lan Mao; Minoru Hongo; Ross Clark; Kirk L. Peterson; John Ross Jr.
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Kinetics and thermodynamics of dimer formation and dissociation for a recombinant humanized monoclonal antibody to vascular endothelial growth factor
Biochemistry, ISSN: 00062960
Jamie M. R. Moore; Thomas W. Patapoff; Cromwell
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Performance comparison of Protein A affinity-chromatography sorbents for purifying recombinant monoclonal antibodies
Biotechnology and Applied Biochemistry, ISSN: 08854513
Fahrner; Duncan H. Whitney; Vanderlaan; Gregory S. Blank
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Susceptibility of rhDNase I to glycation in the dry-powder state
Analytical Chemistry, ISSN: 00032700
Quan; Sylvia Wu; Nancy Dasovich; Chung C. Hsu; Thomas W. Patapoff; Eleanor Canova-Davis
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The S. pombe zfs1 gene is required to prevent septation if mitotic progression is inhibited
Journal of Cell Science, ISSN: 00219533
Nicola Beltraminelli; Maximilien Murone; Viesturs Simanis
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Searching for FLASH domains
Nature, ISSN: 00280836
Eugene V. Koonin; Aravind; Kay Hofmann; Jurg Tschopp; Vishva M. Dixit
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Investigation of recombinant human insulin-like growth factor type I in thymus regeneration in the acute stage of experimental FIV infection in juvenile cats
AIDS Research and Human Retroviruses, ISSN: 08892229
Jennifer C. Woo; Gregg A. Dean; Alora Lavoy; Ross Clark; Peter F. Moore
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Expanded bed protein A affinity chromatography of a recombinant humanized monoclonal antibody: Process development, operation, and comparison with a packed bed method
Journal of Biotechnology, ISSN: 01681656
Fahrner; Gregory S. Blank; Gerardo Zapata
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Quantitative competitive reverse transcription-PCR as a method to evaluate retrovirus removal during chromatography procedures
Journal of Biotechnology, ISSN: 01681656
Allen S.L. Lau; Yolanda S. Lie; Lenore A Norling; Sernatinger; Dinowitz; Christos J. Petropoulos; Yuan Xu
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Analysis of bone age data from National Cooperative Growth Study substudy VII
Pediatrics, ISSN: 00314005
Stephen F. Kemp; Judy P. Sy
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Patterns of medical practice in cystic fibrosis: Part II. Use of therapies
Pediatric Pulmonology, ISSN: 87556863
Michael W. Konstan; Butler; Daniel V. Schidlow; Morgan; Joanne R. Julius; Charles A. Johnson
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Growth hormone stimulation test results as predictors of recombinant human growth hormone treatment outcomes: Preliminary analysis of the National Cooperative Growth Study database
Pediatrics, ISSN: 00314005
George M. Bright; Joanne R. Julius; John Lima; Sandra L. Blethen
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Patterns of medical practice in cystic fibrosis: Part I. Evaluation and monitoring of health status of patients
Pediatric Pulmonology, ISSN: 87556863
Michael W. Konstan; Butler; Daniel V. Schidlow; Morgan; Joanne R. Julius; Charles A. Johnson
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Epidemiologic study of cystic fibrosis: Design and implementation of a prospective, multicenter, observational study of patients with cystic fibrosis in the U.S. and Canada
Pediatric Pulmonology, ISSN: 87556863
Morgan; Butler; Charles A. Johnson; Andrew A. Colin; Stacey C. FitzSimmons; David E. Geller; Michael W. Konstan; Michael Light; Harvey R. Rabin; Warren E. Regelmann; Daniel V. Schidlow; Dennis C. Stokes; Mary Ellen Wohl; Kaplowitz; Matthew M. Wyatt; Scott Stryker
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Knock-out of the neural death effector domain protein PEA-15 demonstrates that its expression protects astrocytes from TNFα-induced apoptosis
Journal of Neuroscience, ISSN: 02706474
Daniel Kitsberg; Etienne Formstecher; Mireille Fauquet; Miroslav Kubes; Jocelyne Cordier; Brigitte Canton; Pan; Malvyne Rolli; Jacques Glowinski; Hervé Chneiweiss
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Antibody phage libraries for the next generation of tumor targeting radioimmunotherapeutics
Clinical Cancer Research, ISSN: 10780432
Sally J. DeNardo; Gerald L. DeNardo; David G. DeNardo; Cheng-Yi Xiong; Xu-Bao Shi; Michelle D. Winthrop; Linda A. Kroger; Paul J. Carter
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Molecular characterization of autosomal recessive chronic granulomatous disease caused by a defect of the nicotinamide adenine dinucleotide phosphate (reduced form) oxidase component p67-phox
Blood, ISSN: 00064971
Pablo Patino; Julie Rae; Noack; Erickson; Jiabing Ding; Diana García De Olarte; John T. Curnutte
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Cleavage of automodified poly(ADP-ribose) polymerase during apoptosis. Evidence for involvement of caspase-7
Journal of Biological Chemistry, ISSN: 00219258
Marc Germain; El Bachir Affar; Damien D'Amours; Vishva M. Dixit; Guy S. Salvesen; Guy G. Poirier
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Adult height in growth hormone deficiency: Historical perspective and examples from the National Cooperative Growth Study
Pediatrics, ISSN: 00314005
J. Paul Frindik; Joyce Baptista
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Regular monitoring of bone age is useful in children treated with growth hormone
Pediatrics, ISSN: 00314005
Francine Ratner Kaufman; Judy P. Sy
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Combined use of growth hormone and gonadotropin-releasing hormone analogues: The National Cooperative Growth Study experience
Pediatrics, ISSN: 00314005
Brenda Kohn; Joanne R. Julius; Sandra L. Blethen
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Regional differences in the developing cerebral cortex revealed by ephrin-A5 expression
Cerebral Cortex, ISSN: 10473211
Katrin Mackarehtschian; Camilla K. Lau; Caras; Susan K. McConnell
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Caspase activation: The induced-proximity model
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Guy S. Salvesen; Vishva M. Dixit
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Molecular and biological properties of vascular endothelial growth factor
Journal of Molecular Medicine, ISSN: 09462716
Napoleone Ferrara
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CD40-CD40 ligand costimulation is required for generating antiviral CD4 T cell responses but is dispensable for CD8 T cell responses
Journal of Immunology, ISSN: 00221767
Jason K. Whitmire; Richard A. Flavell; Iqbal S. Grewal; Christian P. Larsen; Thomas C. Pearson; Rafi Ahmed
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Analyzing mixtures of amino acids and carbohydrates using bi-modal integrated amperometric detection
Journal of Chromatography B: Biomedical Sciences and Applications, ISSN: 13872273
Petr Jandik; Alan P. Clarke; Nebojsa Avdalovic; Dana C. Andersen; Cacia
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The nonclassical class I molecule CD1d associates with the novel CD8 ligand gp180 on intestinal epithelial cells
Journal of Biological Chemistry, ISSN: 00219258
Nicola A. Campbell; Hyun S. Kim; Blumberg; Lloyd Mayer
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The use of a porous graphitic carbon column for desalting hydrophilic peptides prior to matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
Analytical Biochemistry, ISSN: 00032697
Chin; Damon I. Papac
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Crystal structure of nerve growth factor in complex with the ligand- binding domain of the TrkA receptor
Nature, ISSN: 00280836
Christian Wlesmann; Ultsch; Bass; De Vos
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Nonclinical studies addressing the mechanism of action of trastuzumab (Herceptin)
Seminars in Oncology, ISSN: 00937754
Mark X. Sliwkowski; Julie A. Lofgren; Gail D. Lewis; Hotaling; Brian M. Fendly; Judy Fox
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Overview of the trastuzumab (Herceptin) anti-HER2 monoclonal antibody clinical program in HER2-overexpressing metastatic breast cancer
Seminars in Oncology, ISSN: 00937754
Steven Shak
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Multicolor immunofluorescence and flow cytometry utilizing cascade blue to purify murine hematopoietic stem cells from fetal liver and bone marrow
Communications in Clinical Cytometry, ISSN: 01964763
Christopher J. Donahue; Christopher Fennie; Ricardo Villacorta; Hank La; Lasky; Osamu Ohneda
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New cases of pseudomonas aeruginosa: Treatment and outcomes
Pediatric Pulmonology, ISSN: 87556863
Wagener; Butler; Harvey R. Rabin; Warren E. Regelmann; Charles A. Johnson
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A novel mutation in the CYBB gene resulting in an unexpected pattern of exon skipping and chronic granulomatous disease
Biochimica et Biophysica Acta - Molecular Basis of Disease, ISSN: 09254439
Noack; Heyworth; John T. Curnutte; Julie Rae; Andrew R. Cross
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Use of acidic and basic pH and calcium ion addition in the capillary zone electrophoretic characterization of recombinant human deoxyribonuclease, a complex phosphoglycoprotein
Journal of Chromatography A, ISSN: 00219673
Chantal Felten; Quan; Chen; Eleanor Canova-Davis; McNerney; Wolfgang K. Goetzinger; Karger
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Phosphopeptide analysis by on-line immobilized metal-ion affinity chromatography-capillary electrophoresis-electrospray ionization mass spectrometry
Journal of Chromatography A, ISSN: 00219673
Ping Cao; Stults
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Genetic variation in susceptibility to endocrine disruption by estrogen in mice
Science, ISSN: 00368075
Jimmy L. Spearow; Paul Doemeny; Robyn Sera; Rachael Leffler; Marylynn Barkley
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Selection for improved subtiligases by phage display
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Shane Atwell; James A. Wells
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Distribution and function of the adhesion molecule BEN during rat development
Developmental Biology, ISSN: 00121606
Jean-Philippe Stephan; Bald; Penelope E. Roberts; James Lee; Qimin Gu; Mather
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Activation of human neutrophil NADPH oxidase by phosphatidic acid or diacylglycerol in a cell-free system. Activity of diacylglycerol is dependent on its conversion to phosphatidic acid
Journal of Biological Chemistry, ISSN: 00219258
Erickson; Paola Langel-Peveri; Alexis E. Traynor-Kaplan; Heyworth; John T. Curnutte
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Endothelial-monocyte activating polypeptide II, a novel antitumor cytokine that suppresses primary and metastatic tumor growth and induces apoptosis in growing endothelial cells
Journal of Experimental Medicine, ISSN: 00221007
Margaret A. Schwarz; Jessica Kandel; Jerold Brett; Jun Li; Joanne Hayward; Roderich E. Schwarz; Olivier Chappey; Jean-Luc Wautier; John Chabot; Paul Lo Gerfo; David Stern
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Diagnosis and Treatment of Equine Cushing's Disease
Compendium on Continuing Education for the Practicing Veterinarian, ISSN: 01931903
Michel Levy; Janice E. Sojka; Noel Dybdal
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Gene expression analysis by transcript profiling coupled to a gene database query
Nature Biotechnology, ISSN: 10870156
Richard A. Shimkets; David G Lowe; Julie Tsu-Ning Tai; Sehl; Hongkui Jin; Renhui Yang; Paul F. Predki; Bonnie E. G. Rothberg; Michael T. Murtha; Matthew E. Roth; Suresh G. Shenoy; Andreas Windemuth; John W. Simpson; Jan F. Simons; Michael P. Daley; Steven A. Gold; Michael P. McKenna; Kenneth J. Hillan; Gregory T. Went; Jonathan M. Rothberg
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Anaerobic degradation of ethylbenzene and toluene in denitrifying strain EbN1 proceeds via independent substrate-induced pathways
Journal of Molecular Microbiology and Biotechnology, ISSN: 14641801
Kathleen M. Champion; Karsten Zengler; Ralf Rabus
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Constitutive expression of VEGF, VEGFR-1, and VEGFR-2 in normal eyes
Investigative Ophthalmology and Visual Science, ISSN: 01460404
Ivana K. Kim; Anne Ryan; Richard Rohan; Shiro Amano; Stephanie Agular; Joan W. Miller; Anthony P. Adamis
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Multiple Ras effector pathways contribute to G1 cell cycle progression
Journal of Biological Chemistry, ISSN: 00219258
Hendrik Gille; Julian Downward
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Cell activation and apoptosis by bacterial lipoproteins through Toll- like receptor-2
Science, ISSN: 00368075
Antonios O. Aliprantis; Ruey-Bing Yang; Melanie R Mark; Shelly Suggett; Devaux; Justin D. Radolf; Gary R. Klimpel; Godowski; Arturo Zychlinsky
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Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors
Science, ISSN: 00368075
Hans D. Brightbill; Daniel H. Libraty; Stephan R. Krutzik; Ruey-Bing Yang; John T. Belisle; Joshua R. Bleharski; Michael Maitland; Michael V. Norgard; Scott E. Plevy; Stephen T. Smale; Patrick J. Brennan; Bloom; Godowski; Robert L. Modlin
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